BIOGRAPHY AND RESEARCH INTERESTS
ZFIN ID: ZDB-PERS-121011-1
Kwong, E.M.L., Ho, J.C.H., Lau, M.C.C., You, M.S., Jiang, Y.J., Tse, W.K.F. (2017) Restoration of polr1c in early embryogenesis rescues the Type 3 Treacher Collins Syndrome facial malformation phenotype in zebrafish. The American journal of pathology. 188(2):336-342
Lai, K.P., Li, J.W., Hsu, C.H., You, M.S., Chan, T.F., Tse, W.K.F., Jiang, Y.J. (2017) Comparative transcriptomic characterization of a new mib mutant allele, mibnn2002, in zebrafish.. Gene. 642:51-57
Fong, H.C., Ho, J.C., Cheung, A.H., Lai, K.P., Tse, W.K. (2016) Developmental toxicity of the common UV filter, benophenone-2, in zebrafish embryos. Chemosphere. 164:413-420
Lau, M.C., Kwong, E.M., Lai, K.P., Li, J.W., Ho, J.C., Chan, T.F., Wong, C.K., Jiang, Y.J., Tse, W.K. (2016) Pathogenesis of POLR1C-dependent type 3 treacher Collins syndrome revealed by a zebrafish model. Biochimica et biophysica acta. Molecular basis of disease. 1862(6):1147-58
Hsu, C.H., Lin, J.S., Lai, K.P., Li, J.W., Chan, T.F., You, M.S., Tse, W.K., Jiang, Y.J. (2015) A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect.. Scientific Reports. 5:10673
Kamel, G., Hoyos, T., Rochard, L., Dougherty, M., Tse, W., Shubinets, V., Grimaldi, M., and Liao, E.C. (2013) Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis. Developmental Biology. 381(2):423-33
Tse, W.K., Eisenhaber, B., Ho, S.H., Ng, Q., Eisenhaber, F., and Jiang, Y.J. (2009) Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development. BMC Genomics. 10:637
KP. Lai, JW. Li, J. Ge, TF. Chan, WKF. Tse*, CKC. Wong, Transcriptomic analysis reveals specific osmoregulatory adaptive responses in gill mitochondria-rich cells and pavement cells of the Japanese eel. BMC Genomics. 2015. 16: 1072.
WKF. Tse*, J. Sun, H. Zhang, KP. Lai, J. Gu, AYS. Law, BHY. Yeung, SC. Chow, J. Qiu, CKC. Wong. Data for transcriptomic and iTRAQ proteomic analysis of Anguilla japonica gills in response to osmotic stress. Data Brief. 2015. 3: 120-125.
J. Gu, JW. Li, WKF. Tse, TF. Chan, KP. Lai, CKC. Wong. Transcriptomic responses of corpuscle of Stannius gland of Japanese eels (Anguilla japonica) to Changes in Water Salinity. Sci Report. 2015. 5: 9836.
KP. Lai, JW. Li, S. Yuan, JMY. Chiu, SY. A. Tse, K. Lau, S. Lok, DWT. Au, WKF. Tse, CKC. Wong, TF. Chan, RYC. Kong, RSS. Wu. Tissue-specific transcriptome assemblies of the marine medaka Oryzias melastigma and comparative analysis with the freshwater medaka Oryzias latipes. BMC Genomics. 2015. 16: 135.
WKF. Tse*, J. Sun, H. Zhang, KP. Lai, J Gu, J. Qiu, CKC. Wong. iTRAQ-based quantitative proteomic analysis reveals acute hypo-osmotic responsive proteins in the gills of the Japanese eel (Anguilla japonica). J Proteomics. 2014. 105: 133-143.
WKF. Tse*, J. Sun, H. Zhang, AYS. Law, BHY. Yeung, SC. Chow, J. Qiu, CKC. Wong. Transcriptomic and iTRAQ proteomic approaches reveal novel short-term hyperosmotic stress responsive proteins in the gill of the Japanese eel (Anguilla japonica). J Proteomics. 2013. 89: 81-94.
KP. Lai, AYS. Law, MCC. Lau, Y. Takei, WKF. Tse*, CKC. Wong. Osmotic stress transcription factor 1b (Ostf1b) promotes migration properties with the modulation of Epithelial Mesenchymal Transition (EMT) phenotype in human embryonic kidney cell. Int J Biochem Cell Biol. 2013. 45: 1921-1926.
SC. Chow, WKF. Tse, and CKC. Wong. Dexamethasone (DEX) induces Osmotic stress transcription factor 1 (Ostf1) through the Akt-GSK3β pathway in freshwater Japanese eel gill cell cultures. BiO. 2013. 2: 487-491.
WKF. Tse*, SC. Chow, and CKC. Wong. Eel Osmotic Stress Transcriptional Factor 1 (Ostf1) is highly expressed in gill mitochondria-rich cells, where ERK phosphorylated. Front Zool. 2012. 9: 3.
WKF. Tse*, KP. Lai, and Y. Takei. Medaka Osmotic stress transcription factor 1b (Ostf1b/ TSC22D3-2) triggers hyperosmotic responses of different ion transporters in medaka gill and human embryonic kidney cells via the JNK signalling pathway. Int J Biochem Cell Biol. 2011. 43: 1764-1775.
WKF. Tse*, SC. Chow, KP. Lai, DWT. Au, and CKC. Wong. Modulation of ion transporter expression in gill mitochondrion-rich cells of eels acclimated to low-Na+ or -Cl– freshwater. J Exp Zool A. 2011. 315: 385-393.
WKF. Tse*, and CKC. Wong. nbce1 and H+-atpase mRNA expression are stimulated in the mitochondria-rich cells of freshwater acclimating Japanese eels (Anguilla japonica). Can J Zool. 2011. 89: 348-355.
WKF. Tse, SC. Chow, and CKC. Wong. The cloning of eel osmotic stress transcription factor and the regulation of its expression in primary gill cell culture. J Exp Biol. 2008. 211: 1964-68.
WKF. Tse, DWT. Au, and CKC. Wong. Effect of osmotic shrinkage and hormones on the expression of Na+/H+ exchanger-1, Na+/K+/2Cl- cotransporter and Na+/K+-ATPase in gill pavement cells of freshwater adapted Japanese eel, Anguilla japonica. J Exp Biol. 2007. 210: 2113-20.
WKF. Tse, DWT. Au, and CKC. Wong. Characterization of ion channel and transporter mRNA expressions in isolated gill chloride and pavement cells of seawater acclimating eels. Biochem Biophys Res Commun. 2006. 346: 1181-90.
MS. Yang, WKF. Tse, LC. Yu, KM. Li, NK. Mak, and RC. Gupta. Energy and redox states in the C6 glioma cells following acute exposure to Zn, Se+4 and Se+6 and the correlation with apoptosis. Toxicology Mech Method. 2006. 16: 13-19.