ZFIN ID: ZDB-PERS-120509-1
Lowe, Martin
Email: martin.lowe@manchester.ac.uk
URL: http://www.ls.manchester.ac.uk/research/researchgroups/cellorganisationanddynamics/people/?alias=lowem
Affiliation: Lowe Lab
Address: Faculty of Life Sciences University of Manchester Michael Smith Building Oxford Road Manchester M13 9PT UK
Country: UK
Phone: 0044 161 275 5387
Fax: 0044 161 275 5082


De Leo, E., Elmonem, M.A., Berlingerio, S.P., Berquez, M., Festa, B.P., Raso, R., Bellomo, F., Starborg, T., Janssen, M.J., Abbaszadeh, Z., Cairoli, S., Goffredo, B.M., Masereeuw, R., Devuyst, O., Lowe, M., Levtchenko, E., Luciani, A., Emma, F., Rega, L.R. (2020) Cell-Based Phenotypic Drug Screening Identifies Luteolin as Candidate Therapeutic for Nephropathic Cystinosis. Journal of the American Society of Nephrology : JASN. 31(7):1522-1537
Preston, R., Naylor, R.W., Stewart, G., Bierzynska, A., Saleem, M.A., Lowe, M., Lennon, R. (2019) A role for OCRL in glomerular function and disease. Pediatric nephrology (Berlin, Germany). 35(4):641-648
Vaz, F.M., McDermott, J.H., Alders, M., Wortmann, S.B., Kölker, S., Pras-Raves, M.L., Vervaart, M.A.T., van Lenthe, H., Luyf, A.C.M., Elfrink, H.L., Metcalfe, K., Cuvertino, S., Clayton, P.E., Yarwood, R., Lowe, M.P., Lovell, S., Rogers, R.C., Deciphering Developmental Disorders Study, van Kampen, A.H.C., Ruiter, J.P.N., Wanders, R.J.A., Ferdinandusse, S., van Weeghel, M., Engelen, M., Banka, S. (2019) Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia. Brain : a journal of neurology. 142(11):3382-3397
Mondin, V.E., Ben El Kadhi, K., Cauvin, C., Jackson-Crawford, A., Bélanger, E., Decelle, B., Salomon, R., Lowe, M., Echard, A., Carréno, S. (2019) PTEN reduces endosomal PtdIns(4,5)P2 in a phosphatase-independent manner via a PLC pathway. The Journal of cell biology. 218(7):2198-2214
Elmonem, M.A., Berlingerio, S.P., van den Heuvel, L.P., de Witte, P.A., Lowe, M., Levtchenko, E.N. (2018) Genetic Renal Diseases: The Emerging Role of Zebrafish Models. Cells. 7(9)
Elmonem, M.A., Khalil, R., Khodaparast, L., Khodaparast, L., Arcolino, F.O., Morgan, J., Pastore, A., Tylzanowski, P., Ny, A., Lowe, M., de Witte, P.A., Baelde, H.J., van den Heuvel, L.P., Levtchenko, E. (2017) Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction. Scientific Reports. 7:42583
De Leo, M.G., Staiano, L., Vicinanza, M., Luciani, A., Carissimo, A., Mutarelli, M., Di Campli, A., Polishchuk, E., Di Tullio, G., Morra, V., Levtchenko, E., Oltrabella, F., Starborg, T., Santoro, M., di Bernardo, D., Devuyst, O., Lowe, M., Medina, D.L., Ballabio, A., De Matteis, M.A. (2016) Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL. Nature cell biology. 18:839-50
Oltrabella, F., Pietka, G., Ramirez, I.B., Mironov, A., Starborg, T., Drummond, I.A., Hinchliffe, K.A., Lowe, M. (2015) The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule. PLoS Genetics. 11:e1005058
Mehta, Z.B., Pietka, G., and Lowe, M. (2014) The Cellular and Physiological Functions of the Lowe Syndrome Protein OCRL1. Traffic (Copenhagen, Denmark). 15(5):471-487
Jones, D.R., Ramirez, I.B., Lowe, M., and Divecha, N. (2013) Measurement of phosphoinositides in the zebrafish Danio rerio. Nature Protocols. 8(6):1058-1072
Coon, B.G., Hernandez, V., Madhivanan, K., Mukherjee, D., Hanna, C.B., Ramirez, I.B., Lowe, M., Beales, P.L., and Aguilar, R.C. (2012) The Lowe Syndrome Protein OCRL1 is Involved in Primary Cilia Assembly. Human molecular genetics. 21(8):1835-1847
Ramirez, I.B., Pietka, G., Jones, D.R., Divecha, N., Aliam, A., Baraban, S.C., Hurlstone, A.F., and Lowe, M. (2012) Impaired Neural Development in a Zebrafish Model for Lowe Syndrome. Human molecular genetics. 21(8):1744-1759