ZFIN Person: So, Juhoon

ZFIN ID: ZDB-PERS-110209-6

So, Juhoon

Email:	juhoon@pitt.edu
URL:
Affiliation:	Shin Lab
Address:	University of Pittsburgh 3501 5th Ave. #5063 Pittsburgh, PA 15260 USA
Country:	United States
Phone:
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Rizvi, F., Lee, Y.R., Diaz-Aragon, R., Bawa, P.S., So, J., Florentino, R.M., Wu, S., Sarjoo, A., Truong, E., Smith, A.R., Wang, F., Everton, E., Ostrowska, A., Jung, K., Tam, Y., Muramatsu, H., Pardi, N., Weissman, D., Soto-Gutierrez, A., Shin, D., Gouon-Evans, V. (2023) VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis. Cell Stem Cell. 30(12):1640-1657.e8

Kim, M., So, J., Shin, D. (2023) PPARα activation promotes liver progenitor cell-mediated liver regeneration by suppressing YAP signaling in zebrafish. Scientific Reports. 13:1831218312

Glessner, J.T., Ningappa, M.B., Ngo, K.A., Zahid, M., So, J., Higgs, B.W., Sleiman, P.M.A., Narayanan, T., Ranganathan, S., March, M., Prasadan, K., Vaccaro, C., Reyes-Mugica, M., Velazquez, J., Salgado, C.M., Ebrahimkhani, M.R., Schmitt, L., Rajasundaram, D., Paul, M., Pellegrino, R., Gittes, G.K., Li, D., Wang, X., Billings, J., Squires, R., Ashokkumar, C., Sharif, K., Kelly, D., Dhawan, A., Horslen, S., Lo, C.W., Shin, D., Subramaniam, S., Hakonarson, H., Sindhi, R. (2023) Biliary atresia is associated with polygenic susceptibility in ciliogenesis and planar polarity effector genes. Journal of hepatology. 79(6):1385-1395

Lee, S.H., So, J., Shin, D. (2023) Hepatocyte-to-cholangiocyte conversion occurs through transdifferentiation independently of proliferation in zebrafish. Hepatology (Baltimore, Md.). 77(4):1198-1210

Pozo-Morales, M., Garteizgogeascoa, I., Perazzolo, C., So, J., Shin, D., Singh, S.P. (2022) In vivo imaging of calcium dynamics in zebrafish hepatocytes. Hepatology (Baltimore, Md.). 77(3):789-801

Jung, K., Kim, M., So, J., Lee, S.H., Ko, S., Shin, D. (2020) Farnesoid X receptor activation impairs liver progenitor cell-mediated liver regeneration via the PTEN-PI3K-AKT-mTOR axis in zebrafish. Hepatology (Baltimore, Md.). 74(1):397-410

Min, J., Ningappa, M., So, J., Shin, D., Sindhi, R., Subramaniam, S. (2020) Systems Analysis of Biliary Atresia Through Integration of High-Throughput Biological Data. Frontiers in Physiology. 11:966

So, J., Kim, M., Lee, S.H., Ko, S., Lee, D.A., Park, H., Azuma, M., Parsons, M.J., Prober, D., Shin, D. (2020) Attenuating the EGFR-ERK-SOX9 axis promotes liver progenitor cell-mediated liver regeneration in zebrafish. Hepatology (Baltimore, Md.). 73(4):1494-1508

So, J., Khaliq, M., Evason, K., Ninov, N., Martin, B.L., Stainier, D.Y.R., Shin, D. (2017) Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity. Hepatology (Baltimore, Md.). 67(6):2352-2366

Zhao, X., Lorent, K., Wilkins, B., Marchione, D.M., Gillespie, K., Waisbourd-Zinman, O., So, J., Koo, K.A., Shin, D., Porter, J.R., Wells, R.G., Blair, I., Pack, M. (2016) Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish. Hepatology (Baltimore, Md.). 64(3):894-907

Ko, S., Choi, T.Y., Russell, J.O., So, J., Monga, S.P., Shin, D. (2016) Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration. Journal of hepatology. 64(2):316-25

Khaliq, M., Choi, T.Y., So, J., Shin, D. (2015) Id2a is required for hepatic outgrowth during liver development in zebrafish. Mechanisms of Development. 138 Pt 3:399-414

Ningappa, M., So, J., Glessner, J., Ashokkumar, C., Ranganathan, S., Min, J., Higgs, B.W., Sun, Q., Haberman, K., Schmitt, L., Vilarinho, S., Mistry, P.K., Vockley, G., Dhawan, A., Gittes, G.K., Hakonarson, H., Jaffe, R., Subramaniam, S., Shin, D., Sindhi, R. (2015) The Role of ARF6 in Biliary Atresia. PLoS One. 10:e0138381

Baek, Y.Y., Lee, D.K., So, J.H., Kim, C.H., Jeoung, D., Lee, H., Choe, J., Won, M.H., Ha, K.S., Kwon, Y.G., Kim, Y.M. (2015) The tetrapeptide Arg-Leu-Tyr-Glu inhibits VEGF-induced angiogenesis. Biochemical and Biophysical Research Communications. 463(4):532-7

Choi, T.Y., Khaliq, M., Ko, S., So, J., Shin, D. (2015) Hepatocyte-specific Ablation in Zebrafish to Study Biliary-driven Liver Regeneration. Journal of visualized experiments : JoVE. (99):e52785

Delgado, E.R., Yang, J., So, J., Leimgruber, S., Kahn, M., Ishitani, T., Shin, D., Wilson, G.M., Monga, S.P. (2014) Identification and Characterization of a Novel Small-Molecule Inhibitor of beta-Catenin Signaling. The American journal of pathology. 184(7):2111-22

Lee, S.H., So, J.H., Kim, H.T., Choi, J.H., Lee, M.S., Choi, S.Y., Kim, C.H., Kim, M.J. (2014) Angiopoietin-like 3 regulates hepatocyte proliferation and lipid metabolism in zebrafish. Biochemical and Biophysical Research Communications. 446:1237-42

So, J., Martin, B.L., Kimelman, D., and Shin, D. (2013) Wnt/beta-catenin signaling cell-autonomously converts non-hepatic endodermal cells to a liver fate. Biology Open. 2(1):30-36

NON-ZEBRAFISH PUBLICATIONS