ZFIN ID: ZDB-PERS-100823-12
Liu, Jiandong
Email: jiandong_liu@med.unc.edu
Affiliation: Jiandong Liu Lab
Address: Assistant Professor Department of Pathology and Laboratory Medicine McAllister Heart Institute University of North Carolina at Chapel Hill 3312C MBRB CB #7126, 111 Mason Farm Road Chapel Hill, NC 27599-7126
Phone: (919) 962-0326
Fax: (919) 843-2063


Peng, X., Lai, K.S., She, P., Kang, J., Wang, T., Li, G., Zhou, Y., Sun, J., Jin, D., Xu, X., Liao, L., Liu, J., Lee, E., Poss, K.D., Zhong, T.P. (2020) Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration. Journal of molecular cell biology. 13(1):41-58
Battista, N.A., Douglas, D.R., Lane, A.N., Samsa, L.A., Liu, J., Miller, L.A. (2019) Vortex Dynamics in Trabeculated Embryonic Ventricles. Journal of cardiovascular development and disease. 6(1)
Chrispell, J.D., Dong, E., Osawa, S., Liu, J., Cameron, D.J., Weiss, E.R. (2018) Grk1b and Grk7a Both Contribute to the Recovery of the Isolated Cone Photoresponse in Larval Zebrafish. Investigative ophthalmology & visual science. 59:5116-5124
Fleming, N.D., Samsa, L.A., Hassel, D., Qian, L., Liu, J. (2018) Rapamycin attenuates pathological hypertrophy caused by an absence of trabecular formation. Scientific Reports. 8:8584
Brown, D., Samsa, L.A., Ito, C., Ma, H., Batres, K., Arnaout, R., Qian, L., Liu, J. (2017) Neuregulin-1 is essential for nerve plexus formation during cardiac maturation. Journal of Cellular and Molecular Medicine. 22(3):2007-2017
Battista, N.A., Lane, A.N., Liu, J., Miller, L.A. (2017) Fluid dynamics in heart development: effects of hematocrit and trabeculation. Mathematical medicine and biology : a journal of the IMA. 35(4):493-516
Haskell, G.T., Jensen, B.C., Samsa, L.A., Marchuk, D., Huang, W., Skrzynia, C., Tilley, C., Seifert, B.A., Rivera-Muñoz, E.A., Koller, B., Wilhelmsen, K.C., Liu, J., Alhosaini, H., Weck, K.E., Evans, J.P., Berg, J.S. (2017) Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease. Circulation. Cardiovascular genetics. 10(3):e001443
Samsa, L.A., Ito, C.E., Brown, D.R., Qian, L., Liu, J. (2016) IgG-Containing Isoforms of Neuregulin-1 Are Dispensable for Cardiac Trabeculation in Zebrafish. PLoS One. 11:e0166734
Mouillesseaux, K.P., Wiley, D.S., Saunders, L.M., Wylie, L.A., Kushner, E.J., Chong, D.C., Citrin, K.M., Barber, A.T., Park, Y., Kim, J.D., Samsa, L.A., Kim, J., Liu, J., Jin, S.W., Bautch, V.L. (2016) Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6.. Nature communications. 7:13247
Brown, D.R., Samsa, L.A., Qian, L., Liu, J. (2016) Advances in the Study of Heart Development and Disease Using Zebrafish. Journal of cardiovascular development and disease. 3(2)
Samsa, L.A., Fleming, N., Magness, S., Qian, L., Liu, J. (2016) Isolation and Characterization of Single Cells from Zebrafish Embryos. Journal of visualized experiments : JoVE. (109)
Samsa, L.A., Givens, C., Tzima, E., Stainier, D.Y., Qian, L., Liu, J. (2015) Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish. Development (Cambridge, England). 142:4080-91
Zou, J., Tran, D., Baalbaki, M., Tang, L.F., Poon, A., Pelonero, A., Titus, E.W., Yuan, C., Shi, C., Patchava, S., Halper, E., Garg, J., Movsesyan, I., Yin, C., Wu, R., Wilsbacher, L.D., Liu, J., Hager, R.L., Coughlin, S., Jinek, M., Pullinger, C.R., Kane, J.P., Hart, D.O., Kwok, P.Y., Deo, R.C. (2015) An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin. eLIFE. 4:e09406
Staudt, D.W., Liu, J., Thorn, K.S., Stuurman, N., Liebling, M., and Stainier, D.Y. (2014) High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation. Development (Cambridge, England). 141(3):585-593
Samsa, L.A., Yang, B., Liu, J. (2013) Embryonic cardiac chamber maturation: Trabeculation, conduction, and cardiomyocyte proliferation.. American journal of medical genetics. Part C, Seminars in medical genetics. 163C(3):157-68
Liu, J., and Stainier, D.Y. (2012) Zebrafish in the study of early cardiac development. Circulation research. 110(6):870-874
Liu, J., Bressan, M., Hassel, D., Huisken, J., Staudt, D., Kikuchi, K., Poss, K.D., Mikawa, T., and Stainier, D.Y. (2010) A dual role for ErbB2 signaling in cardiac trabeculation. Development (Cambridge, England). 137(22):3867-3875

Liu Z., Wang L., Welch J., Ma H., Zhou Y., Vaseghi H.R., Yu S., Wall J.B., Alimohamadi S., Zheng M., Yin C., Shen W., Prins J., Liu J#., Qian L#. (2017). Single cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte. Nature. 551:100–104. (# co-correspondence).

Zhou Y., Wang L., Liu Z., Alimohamadi S., Liu J., Qian L. (2017). Comparative gene expression analyses reveal distinct molecular signature between induced cardiomyocytes and induced pluripotent stem cell-derived cardiomyocytes. Cell Reports. 20:3014-3024.

Liu Z., Chen O., Wall J., Zheng M., Zhou Y., Wang L., Vaseghi H., Qian L., Liu J. (2017). Systematic comparison of 2A peptides for cloning multi-genes in a polycistronic vector. Sci Rep. 7, 2193 DOI:10.1038/s41598-017-02460-2.
Vaseghi H., Liu J., Qian L. (2017). Molecular barriers to direct cardiac reprogramming. Protein & Cell. 8:724-734.

Kechele D.O., Dunworth W.P., Tricot C.E., Wetzel-Strong S.E., Li M., Ma H., Liu J., Caron K.M. (2016). Endothelial restoration of receptor activity-modifying protein 2 is sufficient to rescue lethality, but survivors develop dilated cardiomyopathy. Hypertension. 68:667-777

Ma H., Yin C., Zhang Y., Qian L., Liu J. (2016). ErbB2 is required for cardiomyocyte in murine neonatal hearts. Gene. 592:325-330.

Vaseghi H., Zhou Y., Wang L., Yin C., Liu J., Qian L. (2016). Generation of an inducible fibroblast cell line for studying direct cardiac reprogramming. Genesis. 54:398-406.

Ma H., Liu J., Qian L. (2016). Fat for Fostering: Regenerating Injured Heart Using Local Adipose Tissue. EBioMedicine. 7:25-26.

Liu Z., Chen O., Zheng M., Wang L., Zhou Y., Yin C., Liu J., Qian L. (2016). Re-patterning of H3K27me3, H3K4me3 and DNA methylation during fibroblast conversion into induced cardiomyocytes. Stem Cell Research. 16:507-518.

Zhou Y., Wang L., Vaseghi H.R., Liu Z., Lu R., Alimohamadi S., Yin C., Fu J., Wang G.G., Liu J., Qian L. (2016). Bmi1 is a key epigenetic barrier to direct cardiac reprogramming. Cell Stem Cell. 18:382–395.

Wang L., Liu Z., Yin C., Zhou Y., Liu J. Qian L. (2015). Improved generation of induced cardiomyocytes using a polycistronic construct expressing optimal ratio of Gata4, Mef2c and Tbx5. J Vis Exp. (105), e53426, doi:10.3791/53426.

Ma H., Wang L., Yin C., Liu J#., Qian L#. (2015). In vivo cardiac reprogramming using an optimal single polycistronic construct. Cardiovasc Res. 108:217-219. (# co-correspondence).

Guo C., Deng Y., Liu J., Qian L. (2015). Cardiomyocyte-specific role of miR-24 in promoting cell survival. J Cell Mol Med. 19:103-112.

Wang L., Liu Z., Yin C., Asfour H., Chen OM., Li Y., Bursac N., Liu J., Qian L. (2015). Stoichiometry of Gata4, Mef2c, and Tbx5 Influences the Efficiency and Quality of Induced Cardiac Myocyte Reprogramming. Circ Res. 116:237-244.

Vogler G., Liu J., Iafe T.W., Migh E., Mihály J., Bodmer R. (2014). Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis. J Cell Biol. 206:909-922.