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Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-100120-1
Özhan, Günes
Email: gunes.ozhan@ibg.org.tr
URL: http://www.ibg.deu.edu.tr/research/research-programmes/stem-cells-development-homeostasis/gunes-ozhan-laboratory/
Affiliation: Özhan Lab
Address: Izmir International Biomedicine and Genome Institute (iBG-izmir) Dokuz Eylül University 35340 Balcova-Izmir, Turkey
Country: Germany
Phone: 0090 232 412 6562
Fax: 0090 232 412 6509
Orcid ID:


BIOGRAPHY AND RESEARCH INTERESTS
2015-curr. Associate Professor-Group Leader, Dokuz Eylül University, Izmir International Biomedicine and Genome Institute, Izmir, Turkey
2014-2015 Assistant Professor-Group Leader, Dokuz Eylül University, Izmir International Biomedicine and Genome Institute, Izmir, Turkey
2009-2013 Postdoctoral fellow, Weidinger Lab, Biotechnology Center & Center for Regenerative Therapies, University of Technology Dresden, Dresden, Germany
2005-2009 Ph.D. Developmental Biology, Max Planck Institute for Developmental Biology, Tubingen, Germany
2003-2005 M.Sc. Molecular Biology, International Max Planck Research School for Molecular Biology, Gottingen, Germany
1999-2003 B.Sc. (with High Honors) Molecular Biology and Genetics, Department of Molecular Biology and Genetics, Middle East Technical University, Ankara, Turkey

Research Interests:
Zebrafish embryonic development
Wnt signaling
Zebrafish organ regeneration


PUBLICATIONS
Özhan, G., Weidinger, G. (2015) Wnt/β-catenin signaling in heart regeneration. Cell regeneration (London, England). 4:3
Kizil, C., Küchler, B., Yan, J.J., Özhan, G., Moro, E., Argenton, F., Brand, M., Weidinger, G., Antos, C.L. (2014) Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization. Development (Cambridge, England). 141:3529-39
Wehner, D., Cizelsky, W., Vasudevaro, M.D., Özhan, G., Haase, C., Kagermeier-Schenk, B., Röder, A., Dorsky, R.I., Moro, E., Argenton, F., Kühl, M., and Weidinger, G. (2014) Wnt/β-Catenin Signaling Defines Organizing Centers that Orchestrate Growth and Differentiation of the Regenerating Zebrafish Caudal Fin. Cell Reports. 6(3):467-481
Luz, M., Spannl-Müller, S., Özhan, G., Kagermeier-Schenk, B., Rhinn, M., Weidinger, G., and Brand, M. (2014) Dynamic Association with Donor Cell Filopodia and Lipid-Modification Are Essential Features of Wnt8a during Patterning of the Zebrafish Neuroectoderm. PLoS One. 9(1):e84922
Özhan, G., Sezgin, E., Wehner, D., Pfister, A.S., Kühl, S.J., Kagermeier-Schenk, B., Kühl, M., Schwille, P., and Weidinger, G. (2013) Lypd6 Enhances Wnt/beta-Catenin Signaling by Promoting Lrp6 Phosphorylation in Raft Plasma Membrane Domains. Developmental Cell. 26(4):331-345
Thieme, S., Gyárfás, T., Richter, C., Özhan, G., Fu, J., Alexopulou, D., Muders, M.H., Michalk, I., Jakob, C., Dahl, A., Klink, B., Bandola, J., Bachmann, M., Schröck, E., Buchholz, F., Stewart, A.F., Weidinger, G., Anastassiadis, K., and Brenner, S. (2013) The histone demethylase UTX regulates stem cell migration and hematopoiesis. Blood. 121(13):2462-2473
Moro, E., Özhan, G., Mongera, A., Beis, D., Wierzbicki, C., Young, R.M., Bournele, D., Domenichini, A., Valdivia, L.E., Lum, L., Chen, C., Amatruda, J.F., Tiso, N., Weidinger, G., and Argenton, F. (2012) In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains. Developmental Biology. 366(2):327-340
Kagermeier-Schenk, B., Wehner, D., Ozhan-Kizil, G., Yamamoto, H., Li, J., Kirchner, K., Hoffmann, C., Stern, P., Kikuchi, A., Schambony, A., and Weidinger, G. (2011) Waif1/5T4 Inhibits Wnt/β-Catenin Signaling and Activates Noncanonical Wnt Pathways by Modifying LRP6 Subcellular Localization. Developmental Cell. 21(6):1129-43

NON-ZEBRAFISH PUBLICATIONS
Gunes Ozhan and Gilbert Weidinger (2014) Wnt Signaling in Development and Disease: Molecular Mechanisms and Biological Functions Restoring Tissue Homeostasis: Wnt Signaling in Tissue Regeneration After Acute Injury.

Ozhan-Kizil G, Havemann J, Gerberding M. (2009) Germ cells in the crustacean Parhyale hawaiensis depend on Vasa protein for their maintenance but not for their formation. Dev Biol.327(1):230-9.