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ZFIN ID: ZDB-PERS-091202-7
Miller, Adam
Email: acmiller@uoneuro.uoregon.edu
URL: http://millerlab.brainbuild.org/
Affiliation: Adam C Miller Lab
Address: Institute of Neuroscience 1425 E 13th Ave Huestis 214 Eugene, OR 97403-1254
Country: United States
Phone: 541.346.4523
Orcid ID: 0000-0001-7519-3677

The human brain is estimated to contain more connections between neurons than the Milky Way has stars! In the Miller lab we are interested in understanding the molecular and activity-based logic of how neural circuits wire together and produce behavior. We study genes, synapses, neural circuits, and behavior, and how they all come together in the zebrafish. We use zebrafish as a model, first because its obviously the best, and also because to solve the big problems of how circuits of a brain are created zebrafish offers the forward and reverse genetic techniques, the cellular and neural activity imaging, and the behavioral accessibility needed to construct a systematic understanding of the complex wiring steps required to make a functional brain.

Bremer, J., Marsden, K.C., Miller, A., Granato, M. (2019) The ubiquitin ligase PHR promotes directional regrowth of spinal zebrafish axons. Communications biology. 2:195
Marsh, A.J., Michel, J.C., Adke, A.P., Heckman, E.L., Miller, A.C. (2017) Asymmetry of an Intracellular Scaffold at Vertebrate Electrical Synapses. Current biology : CB. 27:3561-3567.e4
Miller, A.C., Whitebirch, A.C., Shah, A.N., Marsden, K.C., Granato, M., O'Brien, J., Moens, C.B. (2017) A genetic basis for molecular asymmetry at vertebrate electrical synapses. eLIFE. 6:e25364
Shah, A.N., Davey, C.F., Whitebirch, A.C., Miller, A.C., Moens, C.B. (2016) Rapid Reverse Genetic Screening Using CRISPR in Zebrafish. Zebrafish. 13:152-3
Shah, A.N., Moens, C.B., Miller, A.C. (2016) Targeted candidate gene screens using CRISPR/Cas9 technology. Methods in cell biology. 135:89-106
Shah, A.N., Davey, C.F., Whitebirch, A.C., Miller, A.C., Moens, C.B. (2015) Rapid reverse genetic screening using CRISPR in zebrafish. Nature Methods. 12(6):535-40
Miller, A.C., Voelker, L.H., Shah, A.N., Moens, C.B. (2015) Neurobeachin Is Required Postsynaptically for Electrical and Chemical Synapse Formation. Current biology : CB. 25(1):16-28
Miller, A.C., Obholzer, N.D., Shah, A.N., Megason, S.G., and Moens, C.B. (2013) RNA-seq based mapping and candidate identification of mutations from forward genetic screens. Genome research. 23(4):679-686