ZFIN ID: ZDB-PERS-080909-4
Kindt, Katie
Email: katie.kindt@nih.gov
URL: http://www.nidcd.nih.gov/research/scientists/Pages/Katie-Kindt.aspx
Affiliation: Kindt Lab
Address: National Institute on Deafness and Other Communication Disorders National Institutes of Health Porter Neuroscience Research Center 35A Convent Drive 1D 933 Bethesda, MD 20892 (US Postal Service) Bethesda, MD 20814 (FedEx, UPS, etc) Voice: 301-443-2626 Email: katie.kindt@nih.gov
Country: United States
Phone: 301-443-2626
Fax:
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Kindt, K.S., Akturk, A., Jarysta, A., Day, M., Beirl, A., Flonard, M., Tarchini, B. (2021) EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia. Nature communications. 12:2861
Sheets, L., Holmgren, M., Kindt, K.S. (2021) How Zebrafish Can Drive the Future of Genetic-based Hearing and Balance Research. Journal of the Association for Research in Otolaryngology : JARO. 22(3):215-235
Hudson, A.M., Lockard, G.M., Namjoshi, O.A., Wilson, J.W., Kindt, K.S., Blough, B.E., Coffin, A.B. (2020) Berbamine Analogs Exhibit Differential Protective Effects From Aminoglycoside-Induced Hair Cell Death. Frontiers in Cellular Neuroscience. 14:234
Wong, H.C., Zhang, Q., Beirl, A.J., Petralia, R.S., Wang, Y.X., Kindt, K. (2019) Synaptic mitochondria regulate hair-cell synapse size and function. eLIFE. 8:
Manchanda, A., Chatterjee, P., Bonventre, J.A., Haggard, D.E., Kindt, K.S., Tanguay, R.L., Johnson, C.P. (2019) Otoferlin Depletion Results in Abnormal Synaptic Ribbons and Altered Intracellular Calcium Levels in Zebrafish. Scientific Reports. 9:14273
Lukasz, D., Kindt, K.S. (2018) In Vivo Calcium Imaging of Lateral-line Hair Cells in Larval Zebrafish. Journal of visualized experiments : JoVE. (141):
Angueyra, J.M., Kindt, K.S. (2018) Leveraging Zebrafish to Study Retinal Degenerations. Frontiers in cell and developmental biology. 6:110
Kindt, K.S., Sheets, L. (2018) Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish. Frontiers in cell and developmental biology. 6:114
Matern, M.S., Beirl, A., Ogawa, Y., Song, Y., Paladugu, N., Kindt, K.S., Hertzano, R. (2018) Corrigendum: Transcriptomic Profiling of Zebrafish Hair Cells Using RiboTag. Frontiers in cell and developmental biology. 6:84
Matern, M.S., Beirl, A., Ogawa, Y., Song, Y., Paladugu, N., Kindt, K.S., Hertzano, R. (2018) Transcriptomic Profiling of Zebrafish Hair Cells Using RiboTag. Frontiers in cell and developmental biology. 6:47
Ji, Y.R., Warrier, S., Jiang, T., Wu, D.K., Kindt, K. (2018) Directional selectivity of afferent neurons in zebrafish neuromasts is regulated by Emx2 in presynaptic hair cells. eLIFE. 7
Zhang, Q., Li, S., Wong, H.C., He, X.J., Beirl, A., Petralia, R.S., Wang, Y.X., Kindt, K.S. (2018) Synaptically silent sensory hair cells in zebrafish are recruited after damage. Nature communications. 9:1388
Imtiaz, A., Belyantseva, I.A., Beirl, A.J., Fenollar-Ferrer, C., Bashir, R., Bukhari, I., Bouzid, A., Shaukat, U., Azaiez, H., Booth, K.T., Kahrizi, K., Najmabadi, H., Maqsood, A., Wilson, E.A., Fitzgerald, T.S., Tlili, A., Olszewski, R., Lund, M., Chaudhry, T., Rehman, A.U., Starost, M.F., Waryah, A.M., Hoa, M., Dong, L., Morell, R.J., Smith, R.J.H., Riazuddin, S., Masmoudi, S., Kindt, K., Naz, S., Friedman, T.B. (2017) CDC14A Phosphatase is Essential for Hearing and Male Fertility in Mouse and Human. Human molecular genetics. 27(5):780-798
Graydon, C.W., Manor, U., Kindt, K.S. (2017) In Vivo Ribbon Mobility and Turnover of Ribeye at Zebrafish Hair Cell Synapses. Scientific Reports. 7:7467
Sheets, L., He, X.J., Olt, J., Schreck, M., Petralia, R.S., Wang, Y.X., Zhang, Q., Beirl, A., Nicolson, T., Marcotti, W., Trapani, J.G., Kindt, K.S. (2017) Enlargement of ribbons in zebrafish hair cells increases calcium currents, but disrupts afferent spontaneous activity and timing of stimulus onset. The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(26):6299-6313
Jiang, T., Kindt, K., Wu, D.K. (2017) Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells. eLIFE. 6
Pei, W., Xu, L., Varshney, G.K., Carrington, B., Bishop, K., Jones, M., Huang, S.C., Idol, J., Pretorius, P.R., Beirl, A., Schimmenti, L.A., Kindt, K.S., Sood, R., Burgess, S.M. (2016) Additive reductions in zebrafish PRPS1 activity result in a spectrum of deficiencies modeling several human PRPS1-associated diseases. Scientific Reports. 6:29946
Zhang, Q.X., He, X.J., Wong, H.C., Kindt, K.S. (2016) Functional calcium imaging in zebrafish lateral-line hair cells. Methods in cell biology. 133:229-252
Maeda, R., Kindt, K.S., Mo, W., Morgan, C.P., Erickson, T., Zhao, H., Clemens-Grisham, R., Barr-Gillespie, P.G., Nicolson, T. (2014) Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2. Proceedings of the National Academy of Sciences of the United States of America. 111(35):12907-12
Grisham, R.C., Kindt, K., Finger-Baier, K., Schmid, B., and Nicolson, T. (2013) Mutations in ap1b1 Cause Mistargeting of the Na(+)/K(+)-ATPase Pump in Sensory Hair Cells. PLoS One. 8(4):e60866
Sheets, L., Kindt, K.S., and Nicolson, T. (2012) Presynaptic CaV1.3 Channels Regulate Synaptic Ribbon Size and Are Required for Synaptic Maintenance in Sensory Hair Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(48):17273-17286
Kindt, K.S., Finch, G., and Nicolson, T. (2012) Kinocilia mediate mechanosensitivity in developing zebrafish hair cells. Developmental Cell. 23(2):329-341

NON-ZEBRAFISH PUBLICATIONS
Kindt K, Quast K, Giles A, Hendrey D, Nicastro I, Rankin C, Schafer W., Dopamine Mediates Context-Dependent Modulation of Sensory Plasticity in C. elegans,
Neuron, 2007 55(4): 662-76.

Kindt K*, Viswanath V*, Macpherson L, Quast K, Hu H, Patapoutian A, Schafer WR. Caenorhabditis elegans TRPA-1 functions in mechanosensation, Nat Neurosci., 2007 10: 568-77.

Fr�kj�r-Jensen C, Kindt KS, Rex KA, Suzuki H, Melnik Martinez K, Schafer WR. Effects of Voltage-Gated Calcium Channel Subunit Genes on Calcium Influx in Cultured C. elegans Mechanosensory Neurons. Journal of Neurobiology, 2006 66: 1125-1139.

Sanyal S, Wintle RF, Kindt KS, Nuttley WM, Arvan R, Fitzmaurice P, Bigras E, Merz D, Hebert TE, van der Kooy D, Schafer WR, Culotti JG.and Van Tol, H. Dopamine modulates the plasticity of mechanosensory responses in C. elegans The EMBO Journal, 2004 23: 473�482

Kindt KS*, Tam T*, Whiteman S, Schafer WR. Serotonin promotes G(o)-dependent neuronal migration in Caenorhabditis elegans. Curr Biol., 2002. 12:1738-47.

Hartsel SC, Baas B, Bauer E, Foree LT Jr, Kindt K, Preis H, Scott A, Kwong EH, Ramaswamy M, Wasan KM. Heat-induced superaggregation of amphotericin B modifies its interaction with serum proteins and lipoproteins and stimulation of TNF-alpha. J Pharm Sci., 2001. 90:124-33.

Baas B, Kindt K, Scott A, Scott J, Mikulecky P, Hartsel SC. Activity and kinetics of dissociation and transfer of amphotericin B from a novel delivery form. AAPS PharmSci., 1999. 1: E10.