ZFIN ID: ZDB-PERS-080111-2
Goudarzi, Mehdi
Email: mgoudarzi@fas.harvard.edu
URL: http://labs.mcb.harvard.edu/schier/
Affiliation:
Address: The Biological Labs 16 Divinity Ave Cambridge, MA 02138
Country:
Phone: +1 857 242 8466
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ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS
Born 24 of March 1980, Married

Post doc (May 2014- )
Alex Schier's Lab, Harvard University, Cambridge, MA, USA

Education:
PhD in Cell Biology, "Summa cum Laude" (2007-2013)
Erez Raz Lab, Muenster University, Germany

MSc/PhD program in Molecular Biology (2006-2007)
GZMB, George August university of Goettingen, Goettingen, Germany

PhD student in Bioinformatics
(Left this program to join IMPRS-GPMOLBIO program) (2004-2006)
Institute of Biochemistry and Biophysics (IBB), Tehran University, Tehran, Iran

MSc in Cell and Molecular Biology (2002-2004)
Biology Department, Faculty of Science, Tehran University, Tehran, Iran

BSc in Microbiology (1998-2002)
Biology department, Faculty of Science, Isfahan University, Isfahan, Iran

Awards:
* Leopoldina Postdoctoral fellowship (2014)
* MTZ®-MPI-Award, Max-Planck institute for Molecular Biomedicine, Münster (2012)
* Travel grant for EMBO workshop on " Biophysical Mechanisms of Development", Oeiras, Portugal (2011)
* Max-planck fellowship, IMPRS, GPMOLBIO, Goettingen (2006-2007)
* Exemption from 2 years essential military service for 2nd rank in the seventh Biology Olympiad of Iranian undergraduate students (2001)

PhD Project:
Investigation of the molecular mechanisms through which, Dead End protein (Dnd) controls motility and survival of primordial germ cells in developing zebrafish embryos.


Research Interests:
- Chromatin biology of development
- Non-Protein-coding RNAs in development
- Systems biology


PUBLICATIONS
Goudarzi, M., Berg, K., Pieper, L.M., Schier, A.F. (2019) Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility. eLIFE. 8:
Gross-Thebing, T., Yigit, S., Pfeiffer, J., Reichman-Fried, M., Bandemer, J., Ruckert, C., Rathmer, C., Goudarzi, M., Stehling, M., Tarbashevich, K., Seggewiss, J., Raz, E. (2017) The Vertebrate Protein Dead End Maintains Primordial Germ Cell Fate by Inhibiting Somatic Differentiation. Developmental Cell. 43:704-715.e5
Goudarzi, M., Strate, I., Paksa, A., Lagendijk, A.K., Bakkers, J., and Raz, E. (2013) On the robustness of germ cell migration and microRNA-mediated regulation of chemokine signaling. Nature Genetics. 45(11):1264-1265
Goudarzi, M., Banisch, T.U., Mobin, M.B., Maghelli, N., Tarbashevich, K., Strate, I., van den Berg, J., Blaser, H., Bandemer, S., Paluch, E., Bakkers, J., Toli-Nørrelykke, I.M., and Raz, E. (2012) Identification and Regulation of a Molecular Module for Bleb-Based Cell Motility. Developmental Cell. 23(1):210-218
Slanchev, K., Stebler, J., Goudarzi, M., Cojocaru, V., Weidinger, G., and Raz, E. (2009) Control of Dead end localization and activity – Implications for the function of the protein in antagonizing miRNA function. Mechanisms of Development. 126(3-4):270-277

NON-ZEBRAFISH PUBLICATIONS
Goudarzi M, Raz E: "This paper is interesting as it provides new insights concerning the complex nature of cellular..." Evaluation of: [Feng Y et al. Live imaging of innate immune cell sensing of transformed cells in zebrafish larvae: parallels between tumor initiation and wound inflammation. PLoS Biol. 2010; 8(12):e1000562; doi: 10.1371/journal.pbio.1000562]. Faculty of 1000, 18 Feb 2011. F1000.com/7787956