ZFIN Person: Haffner, Christof

ZFIN ID: ZDB-PERS-070412-1

ZFIN ID: ZDB-PERS-070412-1

Haffner, Christof

Email:	chaffner@med.uni-muenchen.de
URL:	http://haass.web.med.uni-muenchen.de/Research/Junior_Research_Groups/Haffner_Group/index.html
Affiliation:	Haffner Lab
Address:	Department of Biochemistry Ludwig-Maximilians-University Schillerstrasse 44 Muenchen, D-80336 Germany
Country:	Germany
Phone:	(+49) 089 218075-484
Fax:	(+49) 089 218075-415
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

Regulation of the Nodal signaling pathway

PUBLICATIONS

Dettmer, U., Kuhn, P.H., Abou-Ajram, C., Lichtenthaler, S.F., Krueger, M., Kremmer, E., Haass, C., and Haffner, C. (2010) Transmembrane Protein 147 (TMEM147) Is a Novel Component of the Nicalin-NOMO Protein Complex. The Journal of biological chemistry. 285(34):26174-26181

Haffner, C., and Haass, C. (2006) Cellular Functions of gamma-Secretase-Related Proteins. Neuro-degenerative Diseases. 3(4-5):284-289

NON-ZEBRAFISH PUBLICATIONS
Haffner C., Dettmer U., Weiler T. and Haass C. (2007) The Nicastrin-like
Protein Nicalin Regulates Assembly and
Stability of the Nicalin-Nodal Modulator (NOMO) Membrane Protein Complex. J.
Biol. Chem.. 282 (14): 10632-10638

Krawitz, P., Haffner, C., Fluhrer, R., Steiner, H., Schmid, B., and Haass,
C. (2005) Differential localization and identification of a critical
aspartate suggest non-redundant proteolytic functions of the presenlin in
homologues SPPL2b and SPPL3. J. Biol. Chem.. 280(47):39515-39523

Haffner, C., and Haass, C. (2004) The Biochemical and Genetic Odyssey to the
Function of a Nicastrin-Like Protein. Neurodegener. Dis.. 1(4-5):192-195

Haffner, C., Frauli, M., Topp, S., Irmler, M., Hofmann, K., Regula, J.T.,
Bally-Cuif, L., and Haass, C. (2004) Nicalin and its binding partner Nomo
are novel Nodal signaling antagonists. EMBO J.. 23(15):3041-3050