ZFIN ID: ZDB-PERS-060425-1
Ellett, Felix
Email: fellett@mgh.harvard.edu
URL: http://https://www.linkedin.com/in/felix-ellett-693274b9
Affiliation:
Address: Massachusetts General Hospital BioMEMS Resource Center Room 1407, Building 114, 16th Street Charlestown, MA. 02129 USA
Country:
Phone: +1 6177243209
Fax:
Orcid ID: 0000-0003-4941-4346


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Loynes, C.A., Lee, J.A., Robertson, A.L., Steel, M.J., Ellett, F., Feng, Y., Levy, B.D., Whyte, M.K.B., Renshaw, S.A. (2018) PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo.. Science advances. 4:eaar8320
Ellett, F., Pazhakh, V., Pase, L., Benard, E.L., Weerasinghe, H., Azabdaftari, D., Alasmari, S., Andrianopoulos, A., Lieschke, G.J. (2018) Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo. PLoS pathogens. 14:e1007063
Ellett, F., Irimia, D. (2017) Microstructured Devices for Optimized Microinjection and Imaging of Zebrafish Larvae. Journal of visualized experiments : JoVE. (130)
Ellett, F., Irimia, D. (2017) Microstructured Surface Arrays for Injection of Zebrafish Larvae. Zebrafish. 14(2):140-145
Bhuiyan, M.S., Ellett, F., Murray, G.L., Kostoulias, X., Cerqueira, G.M., Schulze, K.E., Mahamad Maifiah, M.H., Li, J., Creek, D.J., Lieschke, G.J., Peleg, A.Y. (2016) Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis. Proc. Natl. Acad. Sci. USA. 113(34):9599-604
Ellett, F., Elks, P.M., Robertson, A.L., Ogryzko, N.V., Renshaw, S.A. (2015) Defining the phenotype of neutrophils following reverse migration in zebrafish. Journal of Leukocyte Biology. 98(6):975-81
Keatinge, M., Bui, H., Menke, A., Chen, Y.C., Sokol, A.M., Bai, Q., Ellett, F., Da Costa, M., Burke, D., Gegg, M., Trollope, L., Payne, T., McTighe, A., Mortiboys, H., de Jager, S., Nuthhall, H., Kuo, M.S., Fleming, A., Schapira, A.H., Renshaw, S.A., Highley, J.R., Chacinska, A., Panula, P., Burton, E.A., O'Neill, M.J., Bandmann, O. (2015) Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death. Human molecular genetics. 24(23):6640-52
Okuda, K.S., Misa, J.P., Oehlers, S.H., Hall, C.J., Ellett, F., Alasmari, S., Lieschke, G.J., Crosier, K.E., Crosier, P.S., Astin, J.W. (2015) A zebrafish model of inflammatory lymphangiogenesis. Biology Open. 4(10):1270-80
Pagán, A.J., Yang, C.T., Cameron, J., Swaim, L.E., Ellett, F., Lieschke, G.J., Ramakrishnan, L. (2015) Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment. Cell Host & Microbe. 18:15-26
Hall, C.J., Boyle, R.H., Astin, J.W., Flores, M.V., Oehlers, S.H., Sanderson, L.E., Ellett, F., Lieschke, G.J., Crosier, K.E., and Crosier, P.S. (2013) Immunoresponsive Gene 1 Augments Bactericidal Activity of Macrophage-Lineage Cells by Regulating β-Oxidation-Dependent Mitochondrial ROS Production. Cell Metabolism. 18(2):265-278
Svahn, A.J., Graeber, M.B., Ellett, F., Lieschke, G.J., Rinkwitz, S., Bennett, M.R., and Becker, T.S. (2013) Development of ramified microglia from early macrophages in the zebrafish optic tectum. Developmental Neurobiology. 73(1):60-71
Palha, N., Guivel-Benhassine, F., Briolat, V., Lutfalla, G., Sourisseau, M., Ellett, F., Wang, C.H., Lieschke, G.J., Herbomel, P., Schwartz, O., and Levraud, J.P. (2013) Real-time whole-body visualization of chikungunya virus infection and host interferon response in zebrafish. PLoS pathogens. 9(9):e1003619
Pase, L., Layton, J.E., Wittmann, C., Ellett, F., Nowell, C.J., Reyes-Aldasoro, C.C., Varma, S., Rogers, K.L., Hall, C.J., Keightley, M.C., Crosier, P.S., Grabher, C., Heath, J.K., Renshaw, S.A., and Lieschke, G.J. (2012) Neutrophil-Delivered Myeloperoxidase Dampens the Hydrogen Peroxide Burst after Tissue Wounding in Zebrafish. Current biology : CB. 22(19):1818-1824
Goldshmit, Y., Matteo, R., Sztal, T., Ellett, F., Frisca, F., Moreno, K., Crombie, D., Lieschke, G.J., Currie, P.D., Sabbadini, R.A., and Pebay, A. (2012) Blockage of Lysophosphatidic Acid Signaling Improves Spinal Cord Injury Outcomes. The American journal of pathology. 181(3):978-992
Benard, E.L., van der Sar, A.M., Ellett, F., Lieschke, G.J., Spaink, H.P., and Meijer, A.H. (2012) Infection of zebrafish embryos with intracellular bacterial pathogens. Journal of visualized experiments : JoVE. (61)
Dworkin, S., Darido, C., Georgy, S.R., Wilanowski, T., Srivastava, S., Ellett, F., Pase, L., Han, Y., Meng, A., Heath, J.K., Lieschke, G.J., and Jane, S.M. (2012) Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways. Development (Cambridge, England). 139(3):525-536
Ellett, F., and Lieschke, G.J. (2012) Computational quantification of fluorescent leukocyte numbers in zebrafish embryos. Methods in enzymology. 506:425-435
Fang, L., Green, S.R., Baek, J.S., Lee, S.H., Ellett, F., Deer, E., Lieschke, G.J., Witztum, J.L., Tsimikas, S., and Miller, Y.I. (2011) In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish. J. Clin. Invest.. 121(12):4861-9
Ellett, F., Pase, L., Hayman, J.W., Andrianopoulos, A., and Lieschke, G.J. (2011) mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish. Blood. 117(4):e49-e56
Ellett, F., and Lieschke, G.J. (2010) Zebrafish as a model for vertebrate hematopoiesis. Current opinion in pharmacology. 10(5):563--570
Ellett, F., Kile, B.T., and Lieschke, G.J. (2009) The role of the ETS factor erg in zebrafish vasculogenesis. Mechanisms of Development. 126(3-4):220-229

NON-ZEBRAFISH PUBLICATIONS