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Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-060424-2
Bonan, Carla Denise
Email: bonan@portoweb.com.br
URL:
Affiliation:
Address: Faculdade de Biociências Pontifícia Universidade Católica do Rio Grande do Sul Porto Alegre, Brazil
Country:
Phone: 55 51 3320 3545/ ext 4158
Fax: 55 513320 3512
Orcid ID:


BIOGRAPHY AND RESEARCH INTERESTS
Zebrafish is an emerging vertebrate model used in many different studies, such as developmental biology, genetics, neurochemistry and toxicology. ATP is a ubiquitous molecule that exerts several actions on CNS. Besides the energetic role, this nucleotide can act on purinergic signaling as neurotransmitter or co-transmitter, released with different molecules, like dopamine, serotonine and acetylcholine. ATP acts on specific P2 receptors, subdivided in two classes: ionotropic P2X receptors and metabotropic P2Y receptors. Inactivation of ATP signal is perfomed by cell-surface enzymes, named ectonucleotidases. The NTPDase family (nucleoside triphosphate diphosphohydrolase) cleaves tri and diphosphonucleosides into monophosphonucleosides, and an ecto-5'-nucleotidase is able to cleave AMP until the neuromodulator adenosine. Adenosine can trigger on inhibitory A1 and A3 and on facilitatory A2A and A2B receptors. Our laboratory investigates ectonucleotidase activities and purinergic signaling in central nervous system of zebrafish. The relationship between purinergic and cholinergic neurotransmission is also our research fields.


PUBLICATIONS
Cruz, F.F., Pereira, T.C.B., Altenhofen, S., da Costa, K.M., Bogo, M.R., Bonan, C.D., Morrone, F.B. (2019) Characterization of the adenosinergic system in a zebrafish embryo radiotherapy model. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 224:108572
Altenhofen, S., Nabinger, D.D., Bitencourt, P.E.R., Bonan, C.D. (2019) Dichlorvos alters morphology and behavior in zebrafish (Danio rerio) larvae. Environmental pollution (Barking, Essex : 1987). 245:1117-1123
da Rocha, A.M., Kist, L.W., Almeida, E.A., Silva, D.G.H., Bonan, C.D., Altenhofen, S., Kaufmann, C.G., Bogo, M.R., Barros, D.M., Oliveira, S., Geraldo, V., Lacerda, R.G., Ferlauto, A.S., Ladeira, L.O., Monserrat, J.M. (2018) Neurotoxicity in zebrafish exposed to carbon nanotubes: Effects on neurotransmitters levels and antioxidant system. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 218:30-35
Macchi, F.S., Pissinate, K., Villela, A.D., Abbadi, B.L., Rodrigues-Junior, V., Nabinger, D.D., Altenhofen, S., Sperotto, N., da Silva Dadda, A., Subtil, F.T., de Freitas, T.F., Erhart Rauber, A.P., Borsoi, A.F., Bonan, C.D., Bizarro, C.V., Basso, L.A., Santos, D.S., Machado, P. (2018) 1H-Benzo[d]imidazoles and 3,4-dihydroquinazolin-4-ones: Design, synthesis and antitubercular activity. European Journal of Medicinal Chemistry. 155:153-164
Rico, E.P., Rosemberg, D.B., Berteli, J.F.A., da Silveira Langoni, A., Souto, A.A., Bogo, M.R., Bonan, C.D., Souza, D.O. (2017) Adenosine deaminase activity and gene expression patterns are altered after chronic ethanol exposure in zebrafish brain. Neurotoxicology and teratology. 65:14-18
Nabinger, D.D., Altenhofen, S., Bitencourt, P.E.R., Nery, L.R., Leite, C.E., Vianna, M.R.M.R., Bonan, C.D. (2017) Nickel exposure alters behavioral parameters in larval and adult zebrafish. The Science of the total environment. 624:1623-1633
Bridi, D., Altenhofen, S., Gonzalez, J.B., Reolon, G.K., Bonan, C.D. (2017) Glyphosate and Roundup® alter morphology and behavior in zebrafish.. Toxicology. 392:32-39
Altenhofen, S., Nabinger, D.D., Wiprich, M.T., Pereira, T.C.B., Bogo, M.R., Bonan, C.D. (2017) Tebuconazole alters morphological, behavioral and neurochemical parameters in larvae and adult zebrafish (Danio rerio). Chemosphere. 180:483-490
Zimmermann, F.F., Gaspary, K.V., Siebel, A.M., Leite, C.E., Kist, L.W., Bogo, M.R., Bonan, C.D. (2017) Analysis of Extracellular Nucleotide Metabolism in Adult Zebrafish After Embryological Exposure to Valproic Acid. Molecular neurobiology. 54(5):3542-3553
Altenhofen, S., Nabinger, D.D., Pereira, T.C.B., Leite, C.E., Bogo, M.R., Bonan, C.D. (2017) Manganese(II) Chloride Alters Nucleotide and Nucleoside Catabolism in Zebrafish (Danio rerio) Adult Brain. Molecular neurobiology. 55(5):3866-3874
Martinelli, L.K.B., Rotta, M., Villela, A.D., Rodrigues-Junior, V.S., Abbadi, B.L., Trindade, R.V., Petersen, G.O., Danesi, G.M., Nery, L.R., Pauli, I., Campos, M.M., Bonan, C.D., de Souza, O.N., Basso, L.A., Santos, D.S. (2017) Functional, thermodynamics, structural and biological studies of in silico-identified inhibitors of Mycobacterium tuberculosis enoyl-ACP(CoA) reductase enzyme. Scientific Reports. 7:46696
Cruz, F.F., Leite, C.E., Kist, L.W., de Oliveira, G.M., Bogo, M.R., Bonan, C.D., Campos, M.M., Morrone, F.B. (2017) Effects of caffeine on behavioral and inflammatory changes elicited by copper in zebrafish larvae: Role of adenosine receptors. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 194:28-36
Rambo, C.L., Mocelin, R., Marcon, M., Villanova, D., Koakoski, G., de Abreu, M.S., Oliveira, T.A., Barcellos, L.J., Piato, A.L., Bonan, C.D. (2017) Gender differences in aggression and cortisol levels in zebrafish subjected to unpredictable chronic stress. Physiology & behavior. 171:50-54
Altenhofen, S., Wiprich, M.T., Nery, L.R., Leite, C.E., Vianna, M.R., Bonan, C.D. (2017) Manganese(II) chloride alters behavioral and neurochemical parameters in larvae and adult zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 182:172-183
Zimmermann, F.F., Gaspary, K.V., Siebel, A.M., Bonan, C.D. (2016) Oxytocin reversed MK-801-induced social interaction and aggression deficits in zebrafish. Behavioural brain research. 311:368-74
da Silva Acosta, D., Danielle, N.M., Altenhofen, S., Luzardo, M.D., da Costa, P.G., Bianchini, A., Bonan, C.D., da Silva, R.S., Dafre, A.L. (2016) Copper at low levels impairs memory of adult zebrafish (Danio rerio) and affects swimming performance of larvae. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 185-186:122-30
Capiotti, K.M., Siebel, A.M., Kist, L.W., Bogo, M.R., Bonan, C.D., Da Silva, R.S. (2016) Hyperglycemia alters E-NTPDases, ecto-5'-nucleotidase, and ectosolic and cytosolic adenosine deaminase activities and expression from encephala of adult zebrafish (Danio rerio). Purinergic signalling. 12(2):211-20
Zimmermann, F.F., Altenhofen, S., Kist, L.W., Leite, C.E., Bogo, M.R., Cognato, G.P., Bonan, C.D. (2016) Unpredictable Chronic Stress Alters Adenosine Metabolism in Zebrafish Brain. Molecular neurobiology. 53(4):2518-28
Pissinate, K., Villela, A.D., Rodrigues-Junior, V., Giacobbo, B.C., Grams, E.S., Abbadi, B.L., Trindade, R.V., Roesler Nery, L., Bonan, C.D., Back, D.F., Campos, M.M., Basso, L.A., Santos, D.S., Machado, P. (2016) 2-(Quinolin-4-yloxy)acetamides Are Active against Drug-Susceptible and Drug-Resistant Mycobacterium tuberculosis Strains. ACS Medicinal Chemistry Letters. 7:235-9
Giacomini, A.C., Abreu, M.S., Giacomini, L.V., Siebel, A.M., Zimerman, F.F., Rambo, C.L., Mocelin, R., Bonan, C.D., Piato, A.L., Barcellos, L.J. (2016) Fluoxetine and diazepam acutely modulate stress induced-behavior. Behavioural brain research. 296:301-10
da Rosa, J.G., Koakoski, G., Piato, A.L., Bogo, M.R., Bonan, C.D., Barcellos, L.J. (2016) Impaired brain StAR and HSP70 gene expression in zebrafish exposed to Methyl-Parathion based insecticide. Journal of toxicology and environmental health. Part A. 79(1):1-7
Vuaden, F.C., Savio, L.E., Rico, E.P., Mussulini, B.H., Rosemberg, D.B., de Oliveira, D.L., Bogo, M.R., Bonan, C.D., Wyse, A.T. (2016) Methionine Exposure Alters Glutamate Uptake and Adenine Nucleotide Hydrolysis in the Zebrafish Brain. Molecular neurobiology. 53(1):200-9
Abreu, M.S., Giacomini, A.C., Gusso, D., Rosa, J.G., Koakoski, G., Kalichak, F., Idalêncio, R., Oliveira, T.A., Barcellos, H.H., Bonan, C.D., Barcellos, L.J. (2016) Acute exposure to waterborne psychoactive drugs attract zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 179:37-43
da Silva, R.B., Siebel, A.M., Bonan, C.D. (2015) The role of purinergic and dopaminergic systems on MK-801-induced antidepressant effects in zebrafish. Pharmacology, biochemistry, and behavior. 139 Pt B:149-57
Nazario, L.R., Antonioli, R., Capiotti, K.M., Hallak, J.E., Zuardi, A.W., Crippa, J.A., Bonan, C.D., da Silva, R.S. (2015) Reprint of "Caffeine protects against memory loss induced by high and non-anxiolytic dose of cannabidiol in adult zebrafish (Danio rerio)". Pharmacology, biochemistry, and behavior. 139(Pt B):134-140
Seibt, K.J., da Luz Oliveira, R., Bogo, M.R., Senger, M.R., Bonan, C.D. (2015) Investigation into effects of antipsychotics on ectonucleotidase and adenosine deaminase in zebrafish brain. Fish physiology and biochemistry. 41(6):1383-92
Siebel, A.M., Menezes, F.P., da Costa Schaefer, I., Petersen, B.D., Bonan, C.D. (2015) Rapamycin suppresses PTZ-induced seizures at different developmental stages of zebrafish. Pharmacology, biochemistry, and behavior. 139 Pt B:163-8
Zimmermann, F.F., Gaspary, K.V., Leite, C.E., De Paula Cognato, G., Bonan, C.D. (2015) Embryological exposure to valproic acid induces social interaction deficits in zebrafish (Danio rerio): A developmental behavior analysis. Neurotoxicology and teratology. 52(Pt A):36-41
Schaefer, I.C., Siebel, A.M., Piato, A.L., Bonan, C.D., Vianna, M.R., Lara, D.R. (2015) The side-by-side exploratory test: a simple automated protocol for the evaluation of adult zebrafish behavior simultaneously with social interaction. Behavioural pharmacology. 26(7 Spec No):691-6
Menezes, F.P., Kist, L.W., Bogo, M.R., Bonan, C.D., Da Silva, R.S. (2015) Evaluation of Age-Dependent Response to NMDA Receptor Antagonism in Zebrafish. Zebrafish. 12(2):137-43
Siebel, A.M., Menezes, F.P., Capiotti, K.M., Kist, L.W., Schaefer, I.D., Frantz, J.Z., Bogo, M.R., Da Silva, R.S., Bonan, C.D. (2015) Role of Adenosine Signaling on Pentylenetetrazole-Induced Seizures in Zebrafish. Zebrafish. 12(2):127-36
Bortolotto, J.W., Melo, G.M., Cognato, G.D., Vianna, M.R., Bonan, C.D. (2015) Modulation of adenosine signaling prevents scopolamine-induced cognitive impairment in zebrafish. Neurobiology of learning and memory. 118:113-9
Nery, L.R., Eltz, N.S., Hackman, C., Fonseca, R., Altenhofen, S., Guerra, H.N., Freitas, V.M., Bonan, C.D., Vianna, M.R. (2014) Brain Intraventricular Injection of Amyloid-β in Zebrafish Embryo Impairs Cognition and Increases Tau Phosphorylation, Effects Reversed by Lithium. PLoS One. 9:e105862
Siebel, A.M., Vianna, M.R., Bonan, C.D. (2014) Pharmacological and Toxicological effects of lithium in zebrafish. ACS Chemical Neuroscience. 5(6):468-76
Bortolotto, J.W., Cognato, G.P., Christoff, R.R., Roesler, L.N., Leite, C.E., Kist, L.W., Bogo, M.R., Vianna, M.R., Bonan, C.D. (2014) Long-term exposure to paraquat alters behavioral parameters and dopamine levels in adult zebrafish (danio rerio). Zebrafish. 11:142-53
Leite, C.E., de Oliveira Maboni, L., Cruz, F.F., Rosemberg, D.B., Zimmermann, F.F., Pereira, T.C., Bogo, M.R., Bonan, C.D., Campos, M.M., Morrone, F.B., and Battastini, A.M. (2013) Involvement of purinergic system in inflammation and toxicity induced by copper in zebrafish larvae. Toxicology and applied pharmacology. 272(3):681-9
Savio, L.E., Vuaden, F.C., Kist, L.W., Pereira, T.C., Rosemberg, D.B., Bogo, M.R., Bonan, C.D., and Wyse, A.T. (2013) Proline-induced changes in acetylcholinesterase activity and gene expression in zebrafish brain: Reversal by antipsychotic drugs. Neuroscience. 250:121-8
Cruz, F.F., Leite, C.E., Pereira, T.C., Bogo, M.R., Bonan, C.D., Battastini, A.M., Campos, M.M., and Morrone, F.B. (2013) Assessment of mercury chloride-induced toxicity and the relevance of P2X7 receptor activation in zebrafish larvae. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 158(3):159-64
Pagnussat, N., Piato, A.L., Schaefer, I.C., Blank, M., Tamborski, A.R., Guerim, L.D., Bonan, C.D., Vianna, M.R., and Lara, D.R. (2013) One for All and All for One: The Importance of Shoaling on Behavioral and Stress Responses in Zebrafish. Zebrafish. 10(3):338-42
Siebel, A.M., Piato, A.L., Schaefer, I.C., Nery, L.R., Bogo, M.R., and Bonan, C.D. (2013) Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish. Pharmacology, biochemistry, and behavior. 104:20-26
Capiotti, K.M., Fazenda, L., Nazario, L.R., Menezes, F.P., Kist, L.W., Bogo, M.R., Da Silva, R.S., Wyse, A.T., and Bonan, C.D. (2013) Arginine exposure alters ectonucleotidase activities and morphology of zebrafish larvae (Danio rerio). International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 31(1):75-81
Dal Forno, G.O., Kist, L.W., de Azevedo, M.B., Fritsch, R.S., Pereira, T.C., Britto, R.S., Guterres, S.S., Külkamp-Guerreiro, I.C., Bonan, C.D., Monserrat, J.M., and Bogo, M.R. (2013) Intraperitoneal Exposure to Nano/Microparticles of Fullerene (C60) Increases Acetylcholinesterase Activity and Lipid Peroxidation in Adult Zebrafish (Danio rerio) Brain. BioMed Research International. 2013:623789
Savio, L.E., Vuaden, F.C., Rosemberg, D.B., Bogo, M.R., Bonan, C.D., and Wyse, A.T. (2012) Long-term proline exposure alters nucleotide catabolism and ectonucleotidase gene expression in zebrafish brain. Metabolic Brain Disease. 27(4):69-75
Cognato, G.P., Bortolotto, J.W., Blazina, A.R., Christoff, R.R., Lara, D.R., Vianna, M.R., and Bonan, C.D. (2012) Y-Maze Memory Task in Zebrafish (Danio rerio): The Role of Glutamatergic and Cholinergic Systems on the Acquisition and Consolidation Periods. Neurobiology of learning and memory. 98(4):321-328
Vuaden, F.C., Savio, L.E., Piato, A.L., Pereira, T.C., Vianna, M.R., Bogo, M.R., Bonan, C.D., and Wyse, A.T. (2012) Long-Term Methionine Exposure Induces Memory Impairment on Inhibitory Avoidance Task and Alters Acetylcholinesterase Activity and Expression in Zebrafish (Danio rerio). Neurochemical research. 37(7):1545-1553
Seibt, K.J., Oliveira, R., Rosemberg, D.B., Savio, L.E., Scherer, E.B., Schmitz, F., Wyse, A.T., and Bonan, C.D. (2012) MK-801 alters Na+, K+-ATPase activity and oxidative status in zebrafish brain: reversal by antipsychotic drugs. Journal of neural transmission (Vienna, Austria : 1996). 119(6):661-667
Pereira, V.M., Bortolotto, J.W., Kist, L.W., Azevedo, M.B., Fritsch, R.S., Oliveira, R.D., Pereira, T.C., Bonan, C.D., Vianna, M.R., and Bogo, M.R. (2012) Endosulfan exposure inhibits brain AChE activity and impairs swimming performance in adult zebrafish (Danio rerio). Neurotoxicology. 33(3):469-475
Baldissarelli, L.A., Capiotti, K.M., Bogo, M.R., Ghisleni, G., and Bonan, C.D. (2012) Arsenic alters behavioral parameters and brain ectonucleotidases activities in zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 155(4):566-572
Savio, L.E., Vuaden, F.C., Piato, A.L., Bonan, C.D., and Wyse, A.T. (2012) Behavioral changes induced by long-term proline exposure are reversed by antipsychotics in zebrafish. Progress in neuro-psychopharmacology & biological psychiatry. 36(2):258-63
Leite, C.E., da Cruz Teixeira, A., Cruz, F.F., Concatto, S.C., Amaral, J.H., Bonan, C.D., Campos, M.M., Morrone, F.B., and Battastini, A.M. (2012) Analytical method for determination of nitric oxide in zebrafish larvae: Toxicological and pharmacological applications. Analytical biochemistry. 421(2):534-540
Ghisleni, G., Capiotti, K.M., Da Silva, R.S., Oses, J.P., Piato, A.L., Soares, V., Bogo, M.R., and Bonan, C.D. (2012) The role of CRH in behavioral responses to acute restraint stress in zebrafish. Progress in neuro-psychopharmacology & biological psychiatry. 36(1):176-82
Rico, E.P., Rosemberg, D.B., Langoni, A.D., Souto, A.A., Dias, R.D., Bogo, M.R., Bonan, C.D., and Souza, D.O. (2011) Chronic ethanol treatment alters purine nucleotide hydrolysis and nucleotidase gene expression pattern in zebrafish brain. Neurotoxicology. 32(6):871-8
Siebel, A.M., Piato, A.L., Capiotti, K.M., Seibt, K.J., Bogo, M.R., and Bonan, C.D. (2011) PTZ-induced seizures inhibit adenosine deamination in adult zebrafish brain membranes. Brain research bulletin. 86(5-6):385-9
Oliveira, R.D., Seibt, K.J., Rico, E.P., Bogo, M.R., and Bonan, C.D. (2011) Inhibitory effect of lithium on nucleotide hydrolysis and acetylcholinesterase activity in zebrafish (Danio rerio) brain. Neurotoxicology and teratology. 33(6):651-7
Rico, E.P., Rosemberg, D.B., Seibt, K.J., Capiotti, K.M., Da Silva, R.S., and Bonan, C.D. (2011) Zebrafish neurotransmitter systems as potential pharmacological and toxicological targets. Neurotoxicology and teratology. 33(6):608-17
Capiotti, K.M., Menezes, F.P., Nazario, L.R., Pohlmann, J.B., Oliveira, G.M., Fazenda, L., Bogo, M.R., Bonan, C.D., and Da Silva, R.S. (2011) Early exposure to caffeine affects gene expression of adenosine receptors, DARPP-32 and BDNF without affecting sensibility and morphology of developing zebrafish (Danio rerio). Neurotoxicology and teratology. 33(6):680-5
Seibt, K.J., Piato, A.L., da Luz Oliveira, R., Capiotti, K.M., Vianna, M.R., and Bonan, C.D. (2011) Antipsychotic drugs reverse MK-801-induced cognitive and social interaction deficits in zebrafish (Danio rerio). Behavioural brain research. 224(1):135-139
Piato, A.L., Rosemberg, D.B., Capiotti, K.M., Siebel, A.M., Herrmann, A.P., Ghisleni, G., Vianna, M.R., Bogo, M.R., Lara, D.R., and Bonan, C.D. (2011) Acute Restraint Stress in Zebrafish: Behavioral Parameters and Purinergic Signaling. Neurochemical research. 36(10):1876-86
Sant'anna, M.C., de Matas Soares, V., Seibt, K.J., Ghisleni, G., Rico, E.P., Rosemberg, D.B., de Oliveira, J.R., Schröder, N., Bonan, C.D., and Bogo, M.R. (2011) Iron exposure modifies acetylcholinesterase activity in zebrafish (Danio rerio) tissues: distinct susceptibility of tissues to iron overload. Fish physiology and biochemistry. 37(3):573-81
Gebauer, D.L., Pagnussat, N., Piato, A.L., Schaefer, I.C., Bonan, C.D., and Lara, D.R. (2011) Effects of anxiolytics in zebrafish: Similarities and differences between benzodiazepines, buspirone and ethanol. Pharmacology, biochemistry, and behavior. 99(3):480-6
Senger, M.R., Seibt, K.J., Ghisleni, G.C., Dias, R.D., Bogo, M.R., and Bonan, C.D. (2011) Aluminum exposure alters behavioral parameters and increases acetylcholinesterase activity in zebrafish (Danio rerio) brain. Cell biology and toxicology. 27(3):199-205
Rosemberg, D.B., Rico, E.P., Mussulini, B.H., Piato, A.L., Calcagnotto, M.E., Bonan, C.D., Dias, R.D., Blaser, R.E., Souza, D.O., and de Oliveira, D.L. (2011) Differences in spatio-temporal behavior of zebrafish in the open tank paradigm after a short-period confinement into dark and bright environments. PLoS One. 6(5):e19397
Piato, A.L., Capiotti, K.M., Tamborski, A.R., Oses, J.P., Barcellos, L.J., Bogo, M.R., Lara, D.R., Vianna, M.R., and Bonan, C.D. (2011) Unpredictable chronic stress model in Zebrafish (Danio rerio): Behavioral and physiological responses. Progress in neuro-psychopharmacology & biological psychiatry. 35(2):561-567
Pereira, T.C., Rico, E.P., Rosemberg, D.B., Schirmer, H., Dias, R.D., Souto, A.A., Bonan, C.D., and Bogo, M.R. (2011) Zebrafish as a model organism to evaluate drugs potentially able to modulate sirtuin expression. Zebrafish. 8(1):9-16
Richetti, S.K., Blank, M., Capiotti, K.M., Piato, A.L., Bogo, M.R., Vianna, M.R., and Bonan, C.D. (2011) Quercetin and rutin prevent scopolamine-induced memory impairment in zebrafish. Behavioural brain research. 217(1):10-15
Kist, L.W., Piato, A.L., da Rosa, J.G., Koakoski, G., Barcellos, L.J., Yunes, J.S., Bonan, C.D., and Bogo, M.R. (2011) Acute Exposure to Microcystin-Producing Cyanobacterium Microcystis aeruginosa Alters Adult Zebrafish (Danio rerio) Swimming Performance Parameters. Journal of Toxicology. 2011:280304
Richetti, S.K., Rosemberg, D.B., Ventura-Lima, J., Monserrat, J.M., Bogo, M.R., and Bonan, C.D. (2011) Acetylcholinesterase activity and antioxidant capacity of zebrafish brain is altered by heavy metal exposure. Neurotoxicology. 32(1):116-122
Seibt, K.J., Oliveira, R.D., Zimmermann, F.F., Capiotti, K.M., Bogo, M.R., Ghisleni, G., and Bonan, C.D. (2010) Antipsychotic drugs prevent the motor hyperactivity induced by psychotomimetic MK-801 in zebrafish (Danio rerio). Behavioural brain research. 214(2):417-422
Rosemberg, D.B., da Rocha, R.F., Rico, E.P., Zanotto-Filho, A., Dias, R.D., Bogo, M.R., Bonan, C.D., Moreira, J.C., Klamt, F., and Souza, D.O. (2010) Taurine prevents enhancement of acetylcholinesterase activity induced by acute ethanol exposure and decreases the level of markers of oxidative stress in zebrafish brain. Neuroscience. 171(3):683-692
Rosemberg, D.B., Kist, L.W., Etchart, R.J., Rico, E.P., Langoni, A.S., Dias, R.D., Bogo, M.R., Bonan, C.D., and Souza, D.O. (2010) Evidence that acute taurine treatment alters extracellular AMP hydrolysis and adenosine deaminase activity in zebrafish brain membranes. Neuroscience letters. 481(2):105-109
Senger, M.R., Rosemberg, D.B., Seibt, K.J., Dias, R.D., Bogo, M.R., and Bonan, C.D. (2010) Influence of mercury chloride on adenosine deaminase activity and gene expression in zebrafish (Danio rerio) brain. Neurotoxicology. 31(3):291-296
Siebel, A.M., Rico, E.P., Capiotti, K.M., Piato, A.L., Cusinato, C.T., Franco, T.M., Bogo, M.R., and Bonan, C.D. (2010) In vitro effects of antiepileptic drugs on acetylcholinesterase and ectonucleotidase activities in zebrafish (Danio rerio) brain. Toxicology in vitro : an international journal published in association with BIBRA. 24(4):1279-1284
Rico, E.P., de Oliveira, D.L., Rosemberg, D.B., Mussulini, B.H., Bonan, C.D., Dias, R.D., Wofchuk, S., Souza, D.O., and Bogo, M.R. (2010) Expression and functional analysis of Na(+)-dependent glutamate transporters from zebrafish brain. Brain research bulletin. 81(4-5):517-523
Rosemberg, D.B., Rico, E.P., Langoni, A.S., Spinelli, J.T., Pereira, T.C., Dias, R.D., Souza, D.O., Bonan, C.D., and Bogo, M.R. (2010) NTPDase family in zebrafish: Nucleotide hydrolysis, molecular identification and gene expression profiles in brain, liver and heart. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 155(3):230-240
Seibt, K.J., Oliveira Rda, L., Rico, E.P., Dias, R.D., Bogo, M.R., and Bonan, C.D. (2009) Typical and atypical antipsychotics alter acetylcholinesterase activity and ache expression in zebrafish (Danio rerio) brain. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 150(1):10-15
Seibt, K.J., Oliveira, R.D., Rico, E.P., Dias, R.D., Bogo, M.R., and Bonan, C.D. (2009) Antipsychotic drugs inhibit nucleotide hydrolysis in zebrafish (Danio rerio) brain membranes. Toxicology in vitro : an international journal published in association with BIBRA. 23(1):78-82
Rosemberg, D.B., Rico, E.P., Senger, M.R., Dias, R.D., Bogo, M.R., Bonan, C.D., and Souza, D.O. (2008) Kinetic characterization of adenosine deaminase activity in zebrafish (Danio rerio) brain. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 151(1):96-101
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