ZFIN ID: ZDB-PERS-031106-3
Bussmann, Jeroen
Email: j.bussmann@chem.leidenuniv.nl
URL: http://www.universiteitleiden.nl/medewerkers/jeroen-bussmann
Affiliation: Bussmann Lab
Address: Faculty of Science, Leiden Institute of Chemistry, Soft Matter Chemistry Gorlaeus Laboratories Einsteinweg 55 2333 CC Leiden roomnumber HB338
Country:
Phone: +31 (0)71 527 4239
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ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Verwilligen, R.A.F., Mulder, L., Araújo, P.M., Carneiro, M., Bussmann, J., Hoekstra, M., Van Eck, M. (2023) Zebrafish as outgroup model to study evolution of scavenger receptor class B type I functions. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1868(6):159308
Bi, D., Unthan, D.M., Hu, L., Bussmann, J., Remaut, K., Barz, M., Zhang, H. (2023) Polysarcosine-based lipid formulations for intracranial delivery of mRNA. Journal of controlled release : official journal of the Controlled Release Society. 356:1-13
Arias-Alpizar, G., Papadopoulou, P., Rios, X., Pulagam, K.R., Moradi, M.A., Pattipeiluhu, R., Bussmann, J., Sommerdijk, N., Llop, J., Kros, A., Campbell, F. (2022) Phase-separated Liposomes Hijack Endogenous Lipoprotein Transport and Metabolism Pathways to Target Subsets of Endothelial Cells in vivo. Advanced Healthcare Materials. 12(10):e2202709
He, Y., Bi, D., Plantinga, J.A., Molema, G., Bussmann, J., Kamps, J.A.A.M. (2022) Development of a Combined Lipid-Based Nanoparticle Formulation for Enhanced siRNA Delivery to Vascular Endothelial Cells. Pharmaceutics. 14(10):
Giselbrecht, J., Pinnapireddy, S.R., Alioglu, F., Sami, H., Sedding, D., Erdmann, F., Janich, C., Schulz-Siegmund, M., Ogris, M., Bakowsky, U., Langner, A., Bussmann, J., Wölk, C. (2022) Investigating 3R In Vivo Approaches for Bio-Distribution and Efficacy Evaluation of Nucleic Acid Nanocarriers: Studies on Peptide-Mimicking Ionizable Lipid. Small (Weinheim an der Bergstrasse, Germany). 18(18):e2107768
Zhang, H., Bussmann, J., Huhnke, F.H., Devoldere, J., Minnaert, A.K., Jiskoot, W., Serwane, F., Spatz, J., Röding, M., De Smedt, S.C., Braeckmans, K., Remaut, K. (2021) Together is Better: mRNA Co-Encapsulation in Lipoplexes is Required to Obtain Ratiometric Co-Delivery and Protein Expression on the Single Cell Level. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(4):e2102072
Huisman, Y., Uphoff, K., Berger, M., Dobrindt, U., Schelhaas, M., Zobel, T., Bussmann, J., van Impel, A., Schulte-Merker, S. (2021) Meningeal lymphatic endothelial cells fulfill scavenger endothelial cell function and cooperate with microglia in waste removal from the brain. Glia. 70(1):35-49
Arias-Alpizar, G., Koch, B., Hamelmann, N.M., Neustrup, M.A., Paulusse, J.M.J., Jiskoot, W., Kros, A., Bussmann, J. (2021) Stabilin-1 is required for the endothelial clearance of small anionic nanoparticles. Nanomedicine : nanotechnology, biology, and medicine. 34:102395
Verwilligen, R.A.F., Bussmann, J., Van Eck, M. (2020) Zebrafish atherosclerosis: Experimental definitions and difficulties. Atherosclerosis.
Saez Talens, V., Arias-Alpizar, G., Makurat, D.M.M., Davis, J., Bussmann, J., Kros, A., Kieltyka, R.E. (2020) Stab2-Mediated Clearance of Supramolecular Polymer Nanoparticles in Zebrafish Embryos. Biomacromolecules. 21(3):1060-1068
Sieber, S., Grossen, P., Bussmann, J., Campbell, F., Kros, A., Witzigmann, D., Huwyler, J. (2019) Zebrafish as a Preclinical In Vivo Screening Model for Nanomedicines. Advanced drug delivery reviews. 151-152:152-168
Askes, S.H.C., Bossert, N., Bussmann, J., Talens, V.S., Meijer, M.S., Kieltyka, R.E., Kros, A., Bonnet, S., Heinrich, D. (2018) Dynamics of dual-fluorescent polymersomes with durable integrity in living cancer cells and zebrafish embryos. Biomaterials. 168:54-63
Tu, J., Bussmann, J., Du, G., Gao, Y., Bouwstra, J.A., Kros, A. (2018) Lipid Bilayer-Coated Mesoporous Silica Nanoparticles Carrying Bovine Hemoglobin towards an Erythrocyte Mimic. International journal of pharmaceutics. 543(1-2):169-178
Campbell, F., Bos, F.L., Sieber, S., Arias-Alpizar, G., Koch, B.E., Huwyler, J., Kros, A., Bussmann, J. (2018) Directing Nanoparticle Biodistribution Through Evasion and Exploitation of Stab2-Dependent Nanoparticle Uptake. ACS nano. 12(3):2138-2150
Sugden, W.W., Meissner, R., Aegerter-Wilmsen, T., Tsaryk, R., Leonard, E.V., Bussmann, J., Hamm, M.J., Herzog, W., Jin, Y., Jakobsson, L., Denz, C., Siekmann, A.F. (2017) Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues. Nature cell biology. 19(6):653-665
Tulotta, C., Stefanescu, C., Beletkaia, E., Bussmann, J., Tarbashevich, K., Schmidt, T., Snaar-Jagalska, B.E. (2016) Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model. Disease models & mechanisms. 9(2):141-53
Harrison, M.R., Bussmann, J., Huang, Y., Zhao, L., Osorio, A., Burns, C.G., Burns, C.E., Sucov, H.M., Siekmann, A.F., Lien, C.L. (2015) Chemokine-guided angiogenesis directs coronary vasculature formation in zebrafish. Developmental Cell. 33:442-54
Bussmann, J., Raz, E. (2015) Chemokine-guided cell migration and motility in zebrafish development. The EMBO journal. 34(10):1309-1318
Hermkens, D.M., van Impel, A., Urasaki, A., Bussmann, J., Duckers, H.J., Schulte-Merker, S. (2015) Sox7 controls arterial specification in conjunction with hey2 and efnb2 function. Development (Cambridge, England). 142(9):1695-704
Xu, C., Hasan, S.S., Schmidt, I., Rocha, S.F., Pitulescu, M.E., Bussmann, J., Meyen, D., Raz, E., Adams, R.H., Siekmann, A.F. (2014) Arteries are formed by vein-derived endothelial tip cells. Nature communications. 5:5758
Huitema, L.F., Apschner, A., Logister, I., Spoorendonk, K.M., Bussmann, J., Hammond, C.L., and Schulte-Merker, S. (2012) Entpd5 is essential for skeletal mineralization and regulates phosphate homeostasis in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 109(52):21372-21377
Bussmann, J., and Schulte-Merker, S. (2011) Rapid BAC selection for tol2-mediated transgenesis in zebrafish. Development (Cambridge, England). 138(19):4327-32
Bussmann, J., Wolfe, S.A., and Siekmann, A.F. (2011) Arterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signaling. Development (Cambridge, England). 138(9):1717-1726
Geudens, I., Herpers, R., Hermans, K., Segura, I., Ruiz de Almodovar, C., Bussmann, J., De Smet, F., Vandevelde, W., Hogan, B.M., Siekmann, A., Claes, F., Moore, J.C., Pistocchi, A.S., Loges, S., Mazzone, M., Mariggi, G., Bruyere, F., Cotelli, F., Kerjaschki, D., Noel, A., Foidart, J.M., Gerhardt, H., Ny, A., Langenberg, T., Lawson, N.D., Duckers, H.J., Schulte-Merker, S., Carmeliet, P., and Dewerchin, M. (2010) Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish. Arterioscler. Thromb. Vasc. Biol.. 30(9):1695-1702
Bussmann, J., Bos, F.L., Urasaki, A., Kawakami, K., Duckers, H.J., and Schulte-Merker, S. (2010) Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk. Development (Cambridge, England). 137(16):2653-2657
van Rooijen, E., Voest, E.E., Logister, I., Bussmann, J., Korving, J., van Eeden, F.J., Giles, R.H., and Schulte-Merker, S. (2010) von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish. Disease models & mechanisms. 3(5-6):343-353
Hogan, B.M., Bos, F.L., Bussmann, J., Witte, M., Chi, N.C., Duckers, H.J., and Schulte-Merker, S. (2009) ccbe1 is required for embryonic lymphangiogenesis and venous sprouting. Nature Genetics. 41(4):396-398
Hogan, B.M., Bussmann, J., Wolburg, H., and Schulte-Merker, S. (2008) ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish. Human molecular genetics. 17(16):2424-2432
Bussmann, J., Lawson, N., Zon, L., Schulte-Merker, S., and Zebrafish Nomenclature Committee. (2008) Zebrafish VEGF receptors: a guideline to nomenclature. PLoS Genetics. 4(5):e1000064
Smith, K.A., Chocron, S., von der Hardt, S., de Pater, E., Soufan, A., Bussmann, J., Schulte-Merker, S., Hammerschmidt, M., and Bakkers, J. (2008) Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Developmental Cell. 14(2):287-297
Bussmann, J., Bakkers, J., and Schulte-Merker, S. (2007) Early Endocardial Morphogenesis Requires Scl/Tal1. PLoS Genetics. 3(8):e140
Besser, J., Bagowski, C.P., Salas-Vidal, E., van Hemert, M.J., Bussmann, J., and Spaink, H.P. (2007) Expression analysis of the family of 14-3-3 proteins in zebrafish development. Gene expression patterns : GEP. 7(4):511-520
Meijer, A.H., Verbeek, F.J., Salas-Vidal, E., Corredor-Adámez, M., Bussman, J., van der Sar, A.M., Otto, G.W., Geisler, R., and Spaink, H.P. (2005) Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection. Molecular immunology. 42(10):1185-1203
Danilova, N., Bussmann, J., Jekosch, K., and Steiner, L.A. (2005) The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z. Nature immunology. 6(3):295-302
Bussmann, J. (2003) Heart development in zebrafish : the traffic jam mutation. Scriptie Wageningen Universiteit. :40p

NON-ZEBRAFISH PUBLICATIONS