ZFIN Person: Paffett-Lugassy, Noelle

ZFIN ID: ZDB-PERS-020717-16

Paffett-Lugassy, Noelle

Email:	lugassy@enders.tch.harvard.edu
URL:
Affiliation:	The Zon Lab and also: Burns Lab
Address:	Howard Hughes Medical Institute Children's Hospital Boston Division of Hematology/Oncology 300 Longwood Avenue, Karp 8 Boston, MA 02115 USA
Country:
Phone:	(617) 919-2075
Fax:	(617) 730-0222
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Paffett-Lugassy, N., Novikov, N., Jeffrey, S., Abrial, M., Guner-Ataman, B., Sakthivel, S., Burns, C.E., Burns, C.G. (2017) Unique developmental trajectories and genetic regulation of ventricular and outflow tract progenitors in the zebrafish second heart field. Development (Cambridge, England). 144(24):4616-4624

Abrial, M., Paffett-Lugassy, N., Jeffrey, S., Jordan, D., O'Loughlin, E., Frederick, C.J., Burns, C.G., Burns, C.E. (2017) TGF-β Signaling Is Necessary and Sufficient for Pharyngeal Arch Artery Angioblast Formation. Cell Reports. 20:973-983

Jahangiri, L., Sharpe, M., Novikov, N., González-Rosa, J.M., Borikova, A., Nevis, K., Paffett-Lugassy, N., Zhao, L., Adams, M., Guner-Ataman, B., Burns, C.E., Burns, C.G. (2016) The AP-1 transcription factor component Fosl2 potentiates the rate of myocardial differentiation from the zebrafish second heart field. Development (Cambridge, England). 143:113-22

Paffett-Lugassy, N., Singh, R., Nevis, K.R., Guner-Ataman, B., O'Loughlin, E., Jahangiri, L., Harvey, R.P., Burns, C.G., and Burns, C.E. (2013) Heart field origin of great vessel precursors relies on nkx2.5-mediated vasculogenesis. Nature cell biology. 15(11):1362-1369

Guner-Ataman, B., Paffett-Lugassy, N., Adams, M.S., Nevis, K.R., Jahangiri, L., Obregon, P., Kikuchi, K., Poss, K.D., Burns, C.E., and Burns, C.G. (2013) Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function. Development (Cambridge, England). 140(6):1353-1363

Paffett-Lugassy, N., Hsia, N., Fraenkel, P.G., Paw, B., Leschinsky, I., Barut, B., Bahary, N., Caro, J., Handin, R., and Zon, L.I. (2007) Functional conservation of erythropoietin signaling in zebrafish. Blood. 110(7):2718-2726

Weber, G.J., Choe, S.E., Dooley, K.A., Paffett-Lugassy, N.N., Zhou, Y., and Zon, L.I. (2005) Mutant-specific gene programs in the zebrafish. Blood. 106(2):521-530

Paffett-Lugassy, N.N., and Zon, L.I. (2005) Analysis of hematopoietic development in the zebrafish. Methods in molecular medicine. 105:171-198

Ransom, D.G., Bahary, N., Niss, K., Traver, D., Burns, C., Trede, N.S., Paffett-Lugassy, N., Saganic, W.J., Lim, C.A., Hersey, C., Zhou, Y., Barut, B.A., Lin, S., Kingsley, P.D., Palis, J., Orkin, S.H., and Zon, L.I. (2004) The Zebrafish moonshine Gene Encodes Transcriptional Intermediary Factor 1gamma, an Essential Regulator of Hematopoiesis. PLoS Biology. 2(8):E237

Davidson, A.J., Dooley, K., Schmidt, B., Paffett-Lugassy, N., White, N., Walderich, B., Odenthal, J., Maischein, H.M., Schulte-Merker, S., Nüsslein-Volhard, C., Thisse, C., Thisse, B., and Zon, L.I. (2001) Functional genomics and mutagenesis screening in the zebrafish identifies genes required for hematopoietic stem cell development. Blood. 98(11):1888

NON-ZEBRAFISH PUBLICATIONS