ZFIN ID: ZDB-PERS-020128-2
King Heiden, Tisha
Email: king-hei.tish@uwlax.edu
Affiliation: King Heiden Lab
Address: Assistant Professor University of Wisconsin La Crosse Department of Biology UWL River Studies Center 3028 Cowley Hall La Crosse, WI 54601 USA
Country: United States
Phone: 608.785.6463

I am intersted in the physiological effects of chronic exposure to endocrine disrupting chemicals on the reproductive success of fishes. Specifically, I am studying the mechanisms by which 2,3,7,8-TCDD alters female reproductive function, using zebrafish as a model organ system.

Baker, T.R., King-Heiden, T.C., Peterson, R.E., Heideman, W. (2014) Dioxin induction of transgenerational inheritance of disease in zebrafish. Molecular and Cellular Endocrinology. 398(1-2):36-41
Wiecinski, P., Metz, K.M., King Heiden, T.C., Louis, K., Mangham, A., Hamers, R.J., Heideman, W., Peterson, R.E., and Pedersen, J.A. (2013) Toxicity of Oxidatively Degraded Quantum Dots. Environmental science & technology. 47(16):9132-9
King Heiden, T.C., Spitsbergen, J., Heideman, W., and Peterson, R.E. (2009) Persistent Adverse Effects on Health and Reproduction Caused by Exposure of Zebrafish to 2,3,7,8-Tetrachlorodibenzo-p-dioxin During Early Development and Gonad Differentiation. Toxicological sciences : an official journal of the Society of Toxicology. 109(1):75-87
Heiden, T.C., Struble, C.A., Rise, M.L., Hessner, M.J., Hutz, R.J., and Carvan, M.J. 3rd. (2008) Molecular targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) within the zebrafish ovary: Insights into TCDD-induced endocrine disruption and reproductive toxicity. Reproductive toxicology (Elmsford, N.Y.). 25(1):47-57
King Heiden, T.C., Dengler, E., Kao, W.J., Heideman, W., and Peterson, R.E. (2007) Developmental toxicity of low generation PAMAM dendrimers in zebrafish. Toxicology and applied pharmacology. 225(1):70-79
King Heiden, T., Carvan, M.J., 3rd, and Hutz, R.J. (2006) Inhibition of Follicular Development, Vitellogenesis and Serum 17{beta} Estradiol Concentrations in Zebrafish Following Chronic, Sublethal Dietary Exposure to 2,3,7,8,-Tetrachlorodibenzo-p-dioxin. Toxicological sciences : an official journal of the Society of Toxicology. 90(2):490-499
Heiden, T.K., Hutz, R.J., and Carvan, M.J. 3rd. (2005) Accumulation, tissue distribution, and maternal transfer of dietary 2,3,7,8,-tetrachlorodibenzo-p-dioxin: impacts on reproductive success of zebrafish. Toxicological sciences : an official journal of the Society of Toxicology. 87(2):497-507

Hutz, RJ, MJ Carvan III, MG Baldridge, LK Conely, and TC King Heiden. 2006. Environmental toxicants and effects on female reproductive function, Review. Trends in Repro. Biol. 2:1-11.

King Heiden, TC, A Neal Haines, C Manire, J Lombardi, and TJ Koob. 2005. Ultrastructure and permeability of the egg capsule of the bonnethead shark, Sphyrna tiburo. J. Exp. Zool. 303A(7):577-589.