ZFIN ID: ZDB-PERS-010221-5
Verkade, Heather
Email: heather.verkade@unimelb.edu.au
URL:
Affiliation: Verkade Laboratory
Address: Department of Biochemistry and Molecular Biology Building 181, Level 3 West University of Melbourne VIC 3010 Australia
Country: Australia
Phone: +61 3 8344 8997
Fax: +61 3 9348 1421
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS
Collaborative projects in using the zebrafish model to understand problems in areas of biochemistry, molecular biology and cell biology.
Signaling in health and disease
Cellular architecture in health and disease.

Improving outcomes in higher education.
University students' approaches to reading and interpreting the literature.
University students' approaches to interpreting and presenting data.


PUBLICATIONS
Chüeh, A.C., Advani, G., Foroutan, M., Smith, J., Ng, N., Nandurkar, H., Lio, D.S., Zhu, H.J., Chong, Y.P., Verkade, H., Fujita, D.J., Bjorge, J., Basheer, F., Lim, J.P., Luk, I., Dhillon, A., Sakthianandeswaren, A., Mouradov, D., Sieber, O., Hollande, F., Mariadason, J.M., Cheng, H.C. (2021) CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation. Oncogene. 40(17):3015-3029
Yip, E., Giousoh, A., Fung, C., Wilding, B., Prakash, M.D., Williams, C., Verkade, H., Bryson-Richardson, R.J., Bird, P.I. (2018) A transgenic zebrafish model of hepatocyte function in human Z α1-antitrypsin deficiency. Biological chemistry. 400(12):1603-1616
Miles, L.B., Mizoguchi, T., Kikuchi, Y., Verkade, H. (2017) A role for planar cell polarity during early endoderm morphogenesis. Biology Open. 6:531-539
Gurevich, D.B., Nguyen, P.D., Siegel, A.L., Ehrlich, O.V., Sonntag, C., Phan, J.M., Berger, S., Ratnayake, D., Hersey, L., Berger, J., Verkade, H., Hall, T.E., Currie, P.D. (2016) Asymmetric division of clonal muscle stem cells coordinates muscle regeneration in vivo. Science (New York, N.Y.). 353(6295):aad9969
Giousoh, A., Vaz, R., Bryson-Richardson, R.J., Whisstock, J.C., Verkade, H., Bird, P.I. (2015) Bone morphogenetic protein/retinoic acid inducible neural-specific protein (brinp) expression during Danio rerio development. Gene expression patterns : GEP. 18(1-2):37-43
Jeffery, J., Neyt, C., Moore, W., Paterson, S., Bower, N.I., Chenevix-Trench, G., Verkade, H., Hogan, B.M., Khanna, K.K. (2015) Cep55 regulates embryonic growth and development by promoting Akt stability in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(5):1999-2009
Miles, L.B., Verkade, H. (2014) TA-Cloning Vectors for Rapid and Cheap Cloning of Zebrafish Transgenesis Constructs. Zebrafish. 11:281-282
Markmiller, S., Cloonan, N., Lardelli, R.M., Doggett, K., Keightley, M.C., Boglev, Y., Trotter, A.J., Ng, A.Y., Wilkins, S.J., Verkade, H., Ober, E.A., Field, H.A., Grimmond, S.M., Lieschke, G.J., Stainier, D.Y., and Heath, J.K. (2014) Minor class splicing shapes the zebrafish transcriptome during development. Proceedings of the National Academy of Sciences of the United States of America. 111(8):3062-3067
Lancman, J.J., Zvenigorodsky, N., Gates, K.P., Zhang, D., Solomon, K., Humphrey, R.K., Kuo, T., Setiawan, L., Verkade, H., Chi, Y.I., Jhala, U.S., Wright, C.V., Stainier, D.Y., and Dong, P.D. (2013) Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb. Development (Cambridge, England). 140(13):2669-2679
Koltowska, K., Apitz, H., Stamataki, D., Hirst, E.M., Verkade, H., Salecker, I., and Ober, E.A. (2013) Ssrp1a controls organogenesis by promoting cell cycle progression and RNA synthesis. Development (Cambridge, England). 140(9):1912-8
Boglev, Y., Badrock, A.P., Trotter, A.J., Du, Q., Richardson, E.J., Parslow, A.C., Markmiller, S.J., Hall, N.E., de Jong-Curtain, T.A., Ng, A.Y., Verkade, H., Ober, E.A., Field, H.A., Shin, D., Shin, C.H., Hannan, K.M., Hannan, R.D., Pearson, R.B., Kim, S.H., Ess, K.C., Lieschke, G.J., Stainier, D.Y., and Heath, J.K. (2013) Autophagy induction is a tor- and tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis. PLoS Genetics. 9(2):e1002379
Schaub, M., Nussbaum, J., Verkade, H., Ober, E.A., Stainier, D.Y., and Sakaguchi, T.F. (2012) Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. Developmental Biology. 363(1):128-137
Curado, S., Ober, E.A., Walsh, S., Cortes-Hernandez, P., Verkade, H., Koehler, C.M., and Stainier, D.Y. (2010) The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model. Disease models & mechanisms. 3(7-8):486-495
de Jong-Curtain, T.A., Parslow, A.C., Trotter, A.J., Hall, N.E., Verkade, H., Tabone, T., Christie, E.L., Crowhurst, M.O., Layton, J.E., Shepherd, I.T., Nixon, S.J., Parton, R.G., Zon, L.I., Stainier, D.Y., Lieschke, G.J., and Heath, J.K. (2009) Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. Gastroenterology. 136(3):902-911
Osborne, N., Brand-Arzamendi, K., Ober, E.A., Jin, S.W., Verkade, H., Holtzman, N.G., Yelon, D., and Stainier, D.Y. (2008) The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish. Current biology : CB. 18(23):1882-1888
Munson, C., Huisken, J., Bit-Avragim, N., Kuo, T., Dong, P.D., Ober, E.A., Verkade, H., Abdelilah-Seyfried, S., and Stainier, D.Y. (2008) Regulation of neurocoel morphogenesis by Pard6gammab. Developmental Biology. 324(1):41-54
Noël, E.S., Casal-Sueiro, A., Busch-Nentwich, E., Verkade, H., Dong, P.D., Stemple, D.L., and Ober, E.A. (2008) Organ-specific requirements for Hdac1 in liver and pancreas formation. Developmental Biology. 322(2):237-250
Mizoguchi, T., Verkade, H., Heath, J.K., Kuroiwa, A., and Kikuchi, Y. (2008) Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation. Development (Cambridge, England). 135(15):2521-2529
Shin, C.H., Chung, W.S., Hong, S.K., Ober, E.A., Verkade, H., Field, H.A., Huisken, J., and Stainier, D.Y. (2008) Multiple roles for Med12 in vertebrate endoderm development. Developmental Biology. 317(2):467-479
Wilkins, S.J., Yoong, S., Verkade, H., Mizoguchi, T., Plowman, S.J., Hancock, J.F., Kikuchi, Y., Heath, J.K., and Perkins, A.C. (2008) Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation. Developmental Biology. 314(1):12-22
Verkade, H., and Heath, J.K. (2008) Wnt signaling mediates diverse developmental processes in zebrafish. Methods in molecular biology (Clifton, N.J.). 469:225-251
Hogan, B.M., Verkade, H., Lieschke, G.J., and Heath, J.K. (2008) Manipulation of gene expression during zebrafish embryonic development using transient approaches. Methods in molecular biology (Clifton, N.J.). 469:273-300
Jin, S.W., Herzog, W., Santoro, M.M., Mitchell, T.S., Frantsve, J., Jungblut, B., Beis, D., Scott, I.C., D'Amico, L.A., Ober, E.A., Verkade, H., Field, H.A., Chi, N.C., Wehman, A.M., Baier, H., and Stainier, D.Y. (2007) A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. Developmental Biology. 307(1):29-42
Ober, E.A., Verkade, H., Field, H.A., and Stainier, D.Y. (2006) Mesodermal Wnt2b signalling positively regulates liver specification. Nature. 442(7103):688-691
Beis, D., Bartman, T., Jin, S.W., Scott, I.C., D'Amico, L.A., Ober, E.A., Verkade, H., Frantsve, J., Field, H.A., Wehman, A., Baier, H., Tallafuss, A., Bally-Cuif, L., Chen, J.N., Stainier, D.Y., and Jungblut, B. (2005) Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development (Cambridge, England). 132(18):4193-4204
Kikuchi, Y., Verkade, H., Reiter, J.F., Kim, C.H., Chitnis, A.B., Kuroiwa, A., and Stainier, D.Y. (2004) Notch signaling can regulate endoderm formation in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 229(4):756-762
Loosli, F., Staub, W., Finger-Baier, K.C., Ober, E.A., Verkade, H., Wittbrodt, J., and Baier, H. (2003) Loss of eyes in zebrafish caused by mutation of chokh/rx3. EMBO reports. 4(9):894-899
Reiter, J.F., Verkade, H., and Stainier, D.Y.R. (2001) Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5. Developmental Biology. 234(2):330-338

NON-ZEBRAFISH PUBLICATIONS
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