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ZFIN ID:
ZDB-PERS-001127-5
Sidi, Samuel
Email:
Samuel_Sidi@dfci.harvard.edu
URL:
Affiliation:
Sidi Lab
Address:
Department of Pediatric Oncology Dana-Farber Cancer Institute Harvard Medical School Mayer Building 630 44 Binney Street Boston, MA 02115 USA
Country:
United States
Phone:
Fax:
ORCID ID:
BIOGRAPHY AND RESEARCH INTERESTS
PUBLICATIONS
Li, Y., Shah, R.B., Sarti, S., Belcher, A.L., Lee, B.J., Gorbatenko, A., Nemati, F., Yu, H., Stanley, Z., Rahman, M., Shao, Z., Silva, J.M., Zha, S., Sidi, S. (2023) A noncanonical IRAK4-IRAK1 pathway counters DNA damage-induced apoptosis independently of TLR/IL-1R signaling. Science signaling. 16:eadh3449eadh3449
Shah, R.B., Kernan, J.L., van Hoogstraten, A., Ando, K., Li, Y., Belcher, A.L., Mininger, I., Bussenault, A.M., Raman, R., Ramanagoudr-Bhojappa, R., Huang, T.T., D'Andrea, A.D., Chandrasekharappa, S.C., Aggarwal, A.K., Thompson, R., Sidi, S. (2021) FANCI functions as a repair/apoptosis switch in response to DNA crosslinks. Developmental Cell. 56:2207-2222.e7
Liu, P.H., Sidi, S. (2019) Targeting the Innate Immune Kinase IRAK1 in Radioresistant Cancer: Double-Edged Sword or One-Two Punch?. Frontiers in oncology. 9:1174
Liu, P.H., Shah, R.B., Li, Y., Arora, A., Ung, P.M., Raman, R., Gorbatenko, A., Kozono, S., Zhou, X.Z., Brechin, V., Barbaro, J.M., Thompson, R., White, R.M., Aguirre-Ghiso, J.A., Heymach, J.V., Lu, K.P., Silva, J.M., Panageas, K.S., Schlessinger, A., Maki, R.G., Skinner, H.D., de Stanchina, E., Sidi, S. (2019) An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy. Nature cell biology. 21(2):203-213
Ando, K., Parsons, M.J., Shah, R.B., Charendoff, C.I., Paris, S.L., Liu, P.H., Fassio, S.R., Rohrman, B.A., Thompson, R., Oberst, A., Sidi, S., Bouchier-Hayes, L. (2017) NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus. The Journal of cell biology. 216:1795-1810
Chen, C.C., Kennedy, R.D., Sidi, S., Look, A.T., and D'Andrea, A.D. (2009) CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors. Molecular Cancer. 8:24
Sidi, S., Sanda, T., Kennedy, R.D., Hagen, A.T., Jette, C.A., Hoffmans, R., Pascual, J., Imamura, S., Kishi, S., Amatruda, J.F., Kanki, J.P., Green, D.R., D'Andrea, A.A., and Look, A.T. (2008) Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3. Cell. 133(5):864-877
Obholzer, N., Wolfson, S., Trapani, J.G., Mo, W., Nechiporuk, A., Busch-Nentwich, E., Seiler, C., Sidi, S., Söllner, C., Duncan, R.N., Boehland, A., and Nicolson, T. (2008) Vesicular glutamate transporter 3 is required for synaptic transmission in zebrafish hair cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(9):2110-2118
Geisler, R., Rauch, G.J., Geiger-Rudolph, S., Albrecht, A., van Bebber, F., Berger, A., Busch-Nentwich, E., Dahm, R., Dekens, M.P., Dooley, C., Elli, A.F.,Gehring, I., Geiger, H., Geisler, M., Glaser, S., Holley, S., Huber, M., Kerr, A., Kirn, A., Knirsch, M., Konantz, M., Kuchler, A.M., Maderspacher, F., Neuhauss, S.C., Nicolson, T., Ober, E.A., Praeg, E., Ray, R., Rentzsch, B., Rick, J.M., Rief, E., Schauerte, H.E., Schepp, C.P., Schonberger, U., Schonthaler, H.B., Seiler, C., Sidi, S., Söllner, C., Wehner, A., Weiler, C., Nüsslein-Volhard, C. (2007) Large-scale mapping of mutations affecting zebrafish development. BMC Genomics. 8(1):11
Sidi, S., and Look, A.T. (2005) Small molecules thwart crash and burn. Nature Chemical Biology. 1(7):351-353
Shin, J.B., Adams, D., Paukert, M., Siba, M., Sidi, S., Levin, M., Gillespie, P.G., and Grunder, S. (2005) Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells. Proceedings of the National Academy of Sciences of the United States of America. 102(35):12572-12577
Seiler, C., Ben-David, O., Sidi, S., Hendrich, O., Rusch, A., Burnside, B., Avraham, K.B., and Nicolson, T. (2004) Myosin VI is required for structural integrity of the apical surface of sensory hair cells in zebrafish. Developmental Biology. 272(2):328-338
Sidi, S., and Rosa, F.M. (2004) Mechanotransduction of hemodynamic forces regulates organogenesis. Medecine sciences : M/S. 20(5):557-561
Paukert, M., Sidi, S., Russell, C., Siba, M., Wilson, S.W., Nicolson, T., and Grunder, S. (2004) A family of acid-sensing ion channels (ASICs) from the zebrafish: Widespread expression in the central nervous system suggests a conserved role in neuronal communication. The Journal of biological chemistry. 279(18):18783-18791
Sidi, S., Busch-Nentwich, E., Friedrich, R., Schoenberger, U., and Nicolson, T. (2004) gemini encodes a zebrafish L-type calcium channel that localizes at sensory hair cell ribbon synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(17):4213-4223
Concha, M.L., Russell, C., Regan, J.C., Tawk, M., Sidi, S., Gilmour, D.T., Kapsimali, M., Sumoy, L., Goldstone, K., Amaya, E., Kimelman, D., Nicolson, T., Gründer, S., Gomperts, M., Clarke, J.D.W., and Wilson, S.W. (2003) Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality. Neuron. 39(3):423-438
Sidi, S., Friedrich, R.W., and Nicolson, T. (2003) NompC TRP channel required for vertebrate sensory hair cell mechanotransduction. Science (New York, N.Y.). 301(5629):96-99
Sidi, S., Goutel, C., Peyriéras, N., and Rosa, F.M. (2003) Maternal induction of ventral fate by zebrafish radar. Proceedings of the National Academy of Sciences of the United States of America. 100(6):3315-3320
Willot, V., Mathieu, J., Lu, Y., Schmid, B., Sidi, S., Yan, Y.-L., Postlethwait, J.H., Mullins, M., Rosa, F., and Peyriéras, N. (2002) Cooperative action of ADMP- and BMP-mediated pathways in regulating cell fates in the zebrafish gastrula. Developmental Biology. 241(1):59-78
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