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General Information
ZIRC
ZFIN ID: ZDB-LAB-990225-6
Moens Lab
PI/Director: Moens, Cecilia
Contact Person: Madill, Sue
Email: smadill@fhcrc.org
URL: http://labs.fhcrc.org/moens/
Address: Howard Hughes Medical Institute Division of Basic Science Fred Hutchinson Cancer Research Center P.O. Box 19024 1100 Fairview Avenue North Seattle, WA 98109-1024 USA
Country: United States
Phone: (206) 667-4342
Fax: (206) 667-3308
Line Designation: fh


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show first 50 of 153 genomic features


STATEMENT OF RESEARCH INTERESTS
(Alternate URL: http://www.hhmi.org/research/investigators/moens.html)

The Moens lab studies four fundamental questions in developmental biology. The first is how a planar epithelium, the neural plate, folds and then cavitates to form the neural tube, the second is how this apparently homogeneous neuroepithelium becomes patterned along its anterior-posterior axis into segments with distinct molecular and neuroanatomical identities, the third is how morphological boundaries form between these segmental domains, and the last is how cells move in a directed way through this complex patterned environment. We address all four questions in the context of the developing zebrafish hindbrain, which has a distinct and well-characterized anterior-posterior polarity divided into morphological segments called rhombomeres, and in which stereotyped migrations occur that position neurons in their functionally relevant contexts. We use the zebrafish as a model system because all four processes, which take place in the first five weeks of human development, occur in rapid sequence during the first two days of zebrafish development. The zebrafish is also optically transparent, externally developing embryo that is exquisitely accessible to embryological manipulation and live imaging. The availability of mutants generated through forward and reverse genetic approaches makes it possible for us to identify the genes and the genetic pathways that regulate these important events in the development of the vertebrate brain.


LAB MEMBERS
Pan, Luyuan Post-Doc Davey, Chrystal Graduate Student Helde, Kathryn Research Staff
Phelps, Ian Research Staff Rhodes, Sean Fish Facility Staff Ma, Taylur Technical Staff
Morgan, John Technical Staff Madill, Sue Administrative Staff Rabena, Yuri
Tjaden, Anja


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Navajas Acedo, J., Voas, M.G., Alexander, R., Woolley, T., Unruh, J.R., Li, H., Moens, C., Piotrowski, T. (2019) PCP and Wnt pathway components act in parallel during zebrafish mechanosensory hair cell orientation. Nature communications. 10:3993
Mathewson, A.W., Berman, D., Moens, C.B. (2019) Microtubules are required for the maintenance of planar cell polarity in monociliated floorplate cells. Developmental Biology. 452(1):21-33
Poudel, K.R., Roh-Johnson, M., Su, A., Ho, T., Mathsyaraja, H., Anderson, S., Grady, W.M., Moens, C.B., Conacci-Sorrell, M., Eisenman, R.N., Bai, J. (2018) Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis. Developmental Cell. 45:738-752.e6
Kidwell, C.U., Su, C.Y., Hibi, M., Moens, C.B. (2018) Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum. Developmental Biology. 438(1):44-56
Raghupathy, R.K., Zhang, X., Liu, F., Alhasani, R.H., Biswas, L., Akhtar, S., Pan, L., Moens, C.B., Li, W., Liu, M., Kennedy, B.N., Shu, X. (2017) Rpgrip1 is required for rod outer segment development and ciliary protein trafficking in zebrafish. Scientific Reports. 7:16881
Roh-Johnson, M., Shah, A.N., Stonick, J.A., Poudel, K.R., Kargl, J., Yang, G.H., di Martino, J., Hernandez, R.E., Gast, C.E., Zarour, L.R., Antoku, S., Houghton, A.M., Bravo-Cordero, J.J., Wong, M.H., Condeelis, J., Moens, C.B. (2017) Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo. Developmental Cell. 43:549-562.e6
Barsh, G.R., Isabella, A.J., Moens, C.B. (2017) Vagus Motor Neuron Topographic Map Determined by Parallel Mechanisms of hox5 Expression and Time of Axon Initiation. Current biology : CB. 27(24):3812-3825.e3
Stainier, D.Y.R., Raz, E., Lawson, N.D., Ekker, S.C., Burdine, R.D., Eisen, J.S., Ingham, P.W., Schulte-Merker, S., Yelon, D., Weinstein, B.M., Mullins, M.C., Wilson, S.W., Ramakrishnan, L., Amacher, S.L., Neuhauss, S.C.F., Meng, A., Mochizuki, N., Panula, P., Moens, C.B. (2017) Guidelines for morpholino use in zebrafish. PLoS Genetics. 13:e1007000
Van De Weghe, J.C., Rusterholz, T.D.S., Latour, B., Grout, M.E., Aldinger, K.A., Shaheen, R., Dempsey, J.C., Maddirevula, S., Cheng, Y.H., Phelps, I.G., Gesemann, M., Goel, H., Birk, O.S., Alanzi, T., Rawashdeh, R., Khan, A.O., Bamshad, M.J., Nickerson, D.A., Neuhauss, S.C.F., Dobyns, W.B., Alkuraya, F.S., Roepman, R., Bachmann-Gagescu, R., Doherty, D. (2017) Mutations in ARMC9, which Encodes a Basal Body Protein, Cause Joubert Syndrome in Humans and Ciliopathy Phenotypes in Zebrafish. American journal of human genetics. 101(1):23-36
Miller, A.C., Whitebirch, A.C., Shah, A.N., Marsden, K.C., Granato, M., O'Brien, J., Moens, C.B. (2017) A genetic basis for molecular asymmetry at vertebrate electrical synapses. eLIFE. 6:e25364
Rossi, A., Gauvrit, S., Marass, M., Pan, L., Moens, C.B., Stainier, D.Y. (2016) Regulation of Vegf signaling by natural and synthetic ligands. Blood. 128(19):2359-2366
Anderson, S., Poudel, K.R., Roh-Johnson, M., Brabletz, T., Yu, M., Borenstein-Auerbach, N., Grady, W.N., Bai, J., Moens, C.B., Eisenman, R.N., Conacci-Sorrell, M. (2016) MYC-nick promotes cell migration by inducing fascin expression and Cdc42 activation. Proceedings of the National Academy of Sciences of the United States of America. 113(37):E5481-90
Stawicki, T.M., Hernandez, L., Esterberg, R., Linbo, T., Owens, K.N., Shah, A.N., Thapa, N., Roberts, B., Moens, C.B., Rubel, E.W., Raible, D.W. (2016) Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish. G3 (Bethesda). 6(7):2225-35
Liu, L., Pan, L., Li, K., Zhang, Y., Zhu, Z., Sun, Y. (2016) Zebrafish Health Conditions in the China Zebrafish Resource Center and 20 Major Chinese Zebrafish Laboratories. Zebrafish. 13 Suppl 1:S8-S18
Shah, A.N., Davey, C.F., Whitebirch, A.C., Miller, A.C., Moens, C.B. (2016) Rapid Reverse Genetic Screening Using CRISPR in Zebrafish. Zebrafish. 13:152-3
Berg, R.D., Levitte, S., O'Sullivan, M.P., O'Leary, S.M., Cambier, C.J., Cameron, J., Takaki, K.K., Moens, C.B., Tobin, D.M., Keane, J., Ramakrishnan, L. (2016) Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration. Cell. 165:139-152
Davey, C.F., Mathewson, A.W., Moens, C.B. (2016) PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration. PLoS Genetics. 12:e1005934
Shah, A.N., Moens, C.B., Miller, A.C. (2016) Targeted candidate gene screens using CRISPR/Cas9 technology. Methods in cell biology. 135:89-106
Bachmann-Gagescu, R., Dona, M., Hetterschijt, L., Tonnaer, E., Peters, T., de Vrieze, E., Mans, D.A., van Beersum, S.E., Phelps, I.G., Arts, H.H., Keunen, J.E., Ueffing, M., Roepman, R., Boldt, K., Doherty, D., Moens, C.B., Neuhauss, S.C., Kremer, H., van Wijk, E. (2015) The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking. PLoS Genetics. 11:e1005575
Kuan, Y.S., Roberson, S., Akitake, C.M., Fortuno, L., Gamse, J., Moens, C., Halpern, M.E. (2015) Distinct requirements for Wntless in habenular development. Developmental Biology. 406(2):117-28
Li-Villarreal, N., Forbes, M.M., Loza, A.J., Chen, J., Ma, T., Helde, K., Moens, C.B., Shin, J., Sawada, A., Hindes, A.E., Dubrulle, J., Schier, A.F., Longmore, G.D., Marlow, F.L., Solnica-Krezel, L. (2015) Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development (Cambridge, England). 142(15):2704-18
Wheway, G., Schmidts, M., Mans, D.A., Szymanska, K., Nguyen, T.M., Racher, H., Phelps, I.G., Toedt, G., Kennedy, J., Wunderlich, K.A., Sorusch, N., Abdelhamed, Z.A., Natarajan, S., Herridge, W., van Reeuwijk, J., Horn, N., Boldt, K., Parry, D.A., Letteboer, S.J., Roosing, S., Adams, M., Bell, S.M., Bond, J., Higgins, J., Morrison, E.E., Tomlinson, D.C., Slaats, G.G., van Dam, T.J., Huang, L., Kessler, K., Giessl, A., Logan, C.V., Boyle, E.A., Shendure, J., Anazi, S., Aldahmesh, M., Al Hazzaa, S., Hegele, R.A., Ober, C., Frosk, P., Mhanni, A.A., Chodirker, B.N., Chudley, A.E., Lamont, R., Bernier, F.P., Beaulieu, C.L., Gordon, P., Pon, R.T., Donahue, C., Barkovich, A.J., Wolf, L., Toomes, C., Thiel, C.T., Boycott, K.M., McKibbin, M., Inglehearn, C.F., Stewart, F., Omran, H., Huynen, M.A., Sergouniotis, P.I., Alkuraya, F.S., Parboosingh, J.S., Innes, A.M., Willoughby, C.E., Giles, R.H., Webster, A.R., Ueffing, M., Blacque, O., Gleeson, J.G., Wolfrum, U., Beales, P.L., Gibson, T., Doherty, D., Mitchison, H.M., Roepman, R., Johnson, C.A. (2015) An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nature cell biology. 17:1074-87
Shah, A.N., Davey, C.F., Whitebirch, A.C., Miller, A.C., Moens, C.B. (2015) Rapid reverse genetic screening using CRISPR in zebrafish. Nature Methods. 12(6):535-40
Xie, X., Pan, L., Sun, Y. (2015) Growing with the world: rapid development of the zebrafish research in China and the China Zebrafish Resource Center. Science China. Life sciences. 58:396-9
Pan, L., Shah, A.N., Phelps, I.G., Doherty, D., Johnson, E.A., Moens, C.B. (2015) Rapid identification and recovery of ENU-induced mutations with next-generation sequencing and Paired-End Low-Error analysis. BMC Genomics. 16:83
Miller, A.C., Voelker, L.H., Shah, A.N., Moens, C.B. (2015) Neurobeachin Is Required Postsynaptically for Electrical and Chemical Synapse Formation. Current biology : CB. 25(1):16-28
Blasky, A.J., Pan, L., Moens, C.B., Appel, B. (2014) Pard3 regulates contact between neural crest cells and the timing of Schwann cell differentiation but is not essential for neural crest migration or myelination. Developmental dynamics : an official publication of the American Association of Anatomists. 243(12):1511-23
Quillien, A., Moore, J.C., Shin, M., Siekmann, A.F., Smith, T., Pan, L., Moens, C.B., Parsons, M.J., Lawson, N.D. (2014) Distinct Notch signaling outputs pattern the developing arterial system. Development (Cambridge, England). 141:1544-52
Su, C.Y., Kemp, H.A., and Moens, C.B. (2014) Cerebellar development in the absence of Gbx function in zebrafish. Developmental Biology. 386(1):181-90
Zigman, M., Laumann-Lipp, N., Titus, T., Postlethwait, J., and Moens, C.B. (2014) Hoxb1b controls oriented cell division, cell shape and microtubule dynamics in neural tube morphogenesis. Development (Cambridge, England). 141(3):639-649
Delaurier, A., Huycke, T.R., Nichols, J.T., Swartz, M.E., Larsen, A., Walker, C., Dowd, J., Pan, L., Moens, C.B., and Kimmel, C.B. (2014) Role of mef2ca in developmental buffering of the zebrafish larval hyoid dermal skeleton. Developmental Biology. 385(2):189-99
Tuz, K., Bachmann-Gagescu, R., O'Day, D.R., Hua, K., Isabella, C.R., Phelps, I.G., Stolarski, A.E., O'Roak, B.J., Dempsey, J.C., Lourenco, C., Alswaid, A., Bönnemann, C.G., Medne, L., Nampoothiri, S., Stark, Z., Leventer, R.J., Topçu, M., Cansu, A., Jagadeesh, S., Done, S., Ishak, G.E., Glass, I.A., Shendure, J., Neuhauss, S.C., Haldeman-Englert, C.R., Doherty, D., and Ferland, R.J. (2014) Mutations in CSPP1 cause primary cilia abnormalities and Joubert syndrome with or without Jeune asphyxiating thoracic dystrophy. American journal of human genetics. 94(1):62-72
Wang, Y., Pan, L., Moens, C.B., and Appel, B. (2014) Notch3 establishes brain vascular integrity by regulating pericyte number. Development (Cambridge, England). 141(2):307-317
Lenkowski, J.R., Qin, Z., Sifuentes, C.J., Thummel, R., Soto, C.M., Moens, C.B., Raymond, P.A.. (2013) Retinal regeneration in adult zebrafish requires regulation of TGFβ signaling. Glia. 61(10):1687-1697
Alunni, A., Krecsmarik, M., Bosco, A., Galant, S., Pan, L., Moens, C.B., and Bally-Cuif, L. (2013) Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium. Development (Cambridge, England). 140(16):3335-47
Pietri, T., Roman, A.C., Guyon, N., Romano, S.A., Washbourne, P., Moens, C.B., de Polavieja, G.G., and Sumbre, G. (2013) The first mecp2-null zebrafish model shows altered motor behaviors. Frontiers in neural circuits. 7:118
Nichols, J.T., Pan, L., Moens, C.B., and Kimmel, C.B. (2013) barx1 represses joints and promotes cartilage in the craniofacial skeleton. Development (Cambridge, England). 140(13):2765-2775
Hewamadduma, C.A., Grierson, A.J., Ma, T.P., Pan, L., Moens, C.B., Ingham, P.W., Ramesh, T., and Shaw, P.J. (2013) Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish. Human molecular genetics. 22(12):2376-86
Miller, A.C., Obholzer, N.D., Shah, A.N., Megason, S.G., and Moens, C.B. (2013) RNA-seq based mapping and candidate identification of mutations from forward genetic screens. Genome research. 23(4):679-686
Choe, C.P., Collazo, A., Trinh, L.A., Pan, L., Moens, C.B., and Crump, J.G. (2013) Wnt-Dependent Epithelial Transitions Drive Pharyngeal Pouch Formation. Developmental Cell. 24(3):296-309
Fior, R., Maxwell, A.A., Ma, T.P., Vezzaro, A., Moens, C.B., Amacher, S.L., Lewis, J., and Saúde, L. (2012) The differentiation and movement of presomitic mesoderm progenitor cells are controlled by Mesogenin 1. Development (Cambridge, England). 139(24):4656-4665
Hinits, Y., Pan, L., Walker, C., Dowd, J., Moens, C.B., and Hughes, S.M. (2012) Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation. Developmental Biology. 369(2):199-210
Manfroid, I., Ghaye, A., Naye, F., Detry, N., Palm, S., Pan, L., Ma, T.P., Huang, W., Rovira, M., Martial, J.A., Parsons, M.J., Moens, C.B., Voz, M.L., and Peers, B. (2012) Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration. Developmental Biology. 366(2):268-278
Du, S., Draper, B.W., Mione, M., Moens, C.B., and Bruce, A.E. (2012) Differential regulation of epiboly initiation and progression by zebrafish Eomesodermin A. Developmental Biology. 362(1):11-23
Cheung, I.D., Bagnat, M., Ma, T.P., Datta, A., Evason, K., Moore, J.C., Lawson, N.D., Mostov, K.E., Moens, C.B., and Stainier, D.Y. (2012) Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. Developmental Biology. 361(1):68-78
Delous, M., Yin, C., Shin, D., Ninov, N., Debrito Carten, J., Pan, L., Ma, T.P., Farber, S.A., Moens, C.B., and Stainier, D.Y. (2012) sox9b Is a Key Regulator of Pancreaticobiliary Ductal System Development. PLoS Genetics. 8(6):e1002754
De Rienzo, G., Bishop, J.A., Mao, Y., Pan, L., Ma, T.P., Moens, C.B., Tsai, L.H., and Sive, H. (2011) Disc1 regulates both β-catenin-mediated and noncanonical Wnt signaling during vertebrate embryogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25(12):4184-97
Bachmann-Gagescu, R., Phelps, I.G., Stearns, G., Link, B.A., Brockerhoff, S.E., Moens, C.B., and Doherty, D. (2011) The Ciliopathy Gene cc2d2a controls Zebrafish Photoreceptor Outer Segment Development Through a Role in Rab8-dependent Vesicle Trafficking. Human molecular genetics. 20(20):4041-55
Hinits, Y., Williams, V.C., Sweetman, D., Donn, T.M., Ma, T.P., Moens, C.B., and Hughes, S.M. (2011) Defective cranial skeletal development, larval lethality and haploinsufficiency in Myod mutant zebrafish. Developmental Biology. 358(1):102-12
Banerjee, S., Gordon, L., Donn, T.M., Berti, C., Moens, C.B., Burden, S.J., and Granato, M. (2011) A novel role for MuSK and non-canonical Wnt signaling during segmental neural crest cell migration. Development (Cambridge, England). 138(15):3287-3296
Huang, H.Y., Houwing, S., Kaaij, L.J., Meppelink, A., Redl, S., Gauci, S., Vos, H., Draper, B.W., Moens, C.B., Burgering, B.M., Ladurner, P., Krijgsveld, J., Berezikov, E., and Ketting, R.F. (2011) Tdrd1 acts as a molecular scaffold for Piwi proteins and piRNA targets in zebrafish. The EMBO journal. 30(16):3298-308
Taylor, R.W., Qi, J.Y., Talaga, A.K., Ma, T.P., Pan, L., Bartholomew, C.R., Klionsky, D.J., Moens, C.B., and Gamse, J.T. (2011) Asymmetric inhibition of ulk2 causes left-right differences in habenular neuropil formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(27):9869-9878
Walsh, G.S., Grant, P.K., Morgan, J.A., and Moens, C.B. (2011) Planar polarity pathway and Nance-Horan syndrome-like 1b have essential cell-autonomous functions in neuronal migration. Development (Cambridge, England). 138(14):3033-3042
Mapp, O.M., Walsh, G.S., Moens, C.B., Tada, M., and Prince, V.E. (2011) Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity. Development (Cambridge, England). 138(10):2121-2132
Zigman, M., Trinh, L.A., Fraser, S.E., and Moens, C.B. (2011) Zebrafish Neural Tube Morphogenesis Requires Scribble-Dependent Oriented Cell Divisions. Current biology : CB. 21(1):79-86
Grant, P.K., and Moens, C.B. (2010) The neuroepithelial basement membrane serves as a boundary and a substrate for neuron migration in the zebrafish hindbrain. Neural Development. 5:9
Tobin, D.M., Vary, J.C. Jr, Ray, J.P., Walsh, G.S., Dunstan, S.J., Bang, N.D., Hagge, D.A., Khadge, S., King, M.C., Hawn, T.R., Moens, C.B., and Ramakrishnan, L. (2010) The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans. Cell. 140(5):717-730
Davey, C., Tallafuss, A., and Washbourne, P. (2010) Differential expression of neuroligin genes in the nervous system of zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 239(2):703-714
Feng, L., Hernandez, R.E., Waxman, J.S., Yelon, D., and Moens, C.B. (2010) Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism. Developmental Biology. 338(1):1-14
Moens, C.B. and ZFIN Staff (2009) Curation of TILLING Database Links. ZFIN Direct Data Submission.
Boon, K.L., Xiao, S., McWhorter, M.L., Donn, T., Wolf-Saxon, E., Bohnsack, M.T., Moens, C.B., and Beattie, C.E. (2009) Zebrafish survival motor neuron Mutants Exhibit Presynaptic Neuromuscular Junction Defects. Human molecular genetics. 18(19):3615-3625
Maves, L., Tyler, A., Moens, C.B., and Tapscott, S.J. (2009) Pbx acts with Hand2 in early myocardial differentiation. Developmental Biology. 333(2):409-418
Monk, K.R., Naylor, S.G., Glenn, T.D., Mercurio, S., Perlin, J.R., Dominguez, C., Moens, C.B., and Talbot, W.S. (2009) A G protein-coupled receptor is essential for Schwann cells to initiate myelination. Science (New York, N.Y.). 325(5946):1402-1405
Kemp, H.A., Carmany-Rampey, A., and Moens, C. (2009) Generating chimeric zebrafish embryos by transplantation. Journal of visualized experiments : JoVE. (29)
Draper, B.W., and Moens, C.B. (2009) A high-throughput method for zebrafish sperm cryopreservation and in vitro fertilization. Journal of visualized experiments : JoVE. (29)
Walker, C., Walsh, G.S., and Moens, C. (2009) Making gynogenetic diploid zebrafish by early pressure. Journal of visualized experiments : JoVE. (28)
Kemp, H.A., Cooke, J.E., and Moens, C.B. (2009) EphA4 and EfnB2a maintain rhombomere coherence by independently regulating intercalation of progenitor cells in the zebrafish neural keel. Developmental Biology. 327(2):313-326
Gorden, N.T., Arts, H.H., Parisi, M.A., Coene, K.L., Letteboer, S.J., van Beersum, S.E., Mans, D.A., Hikida, A., Eckert, M., Knutzen, D., Alswaid, A.F., Ozyurek, H., Dibooglu, S., Otto, E.A., Liu, Y., Davis, E.E., Hutter, C.M., Bammler, T.K., Farin, F.M., Dorschner, M., Topçu, M., Zackai, E.H., Rosenthal, P., Owens, K.N., Katsanis, N., Vincent, J.B., Hildebrandt, F., Rubel, E.W., Raible, D.W., Knoers, N.V., Chance, P.F., Roepman, R., Moens, C.B., Glass, I.A., and Doherty, D. (2008) CC2D2A Is Mutated in Joubert Syndrome and Interacts with the Ciliopathy-Associated Basal Body Protein CEP290. American journal of human genetics. 83(5):559-571
Moens, C.B., Donn, T.M., Wolf-Saxon, E.R., and Ma, T.P. (2008) Reverse genetics in zebrafish by TILLING. Briefings in functional genomics & proteomics. 7(6):454-459
Stickney, H.L., Imai, Y., Draper, B., Moens, C. and Talbot, W.S. (2007) Zebrafish bmp4 functions during late gastrulation to specify ventroposterior cell fates. Developmental Biology. 310(1):71-84
Maves, L., Waskiewicz, A.J., Paul, B., Cao, Y., Tyler, A., Moens, C.B., and Tapscott, S.J. (2007) Pbx homeodomain proteins direct Myod activity to promote fast-muscle differentiation. Development (Cambridge, England). 134(18):3371-3382
French, C.R., Erickson, T., Callander, D., Berry, K.M., Koss, R., Hagey, D.W., Stout, J., Wuennenberg-Stapleton, K., Ngai, J., Moens, C.B., and Waskiewicz, A.J. (2007) Pbx homeodomain proteins pattern both the zebrafish retina and tectum. BMC Developmental Biology. 7(1):85
Draper, B.W., McCallum, C.M., and Moens, C.B. (2007) nanos1 is required to maintain oocyte production in adult zebrafish. Developmental Biology. 305(2):589-598
Houwing, S., Kamminga, L.M., Berezikov, E., Cronembold, D., Girard, A., van den Elst, H., Filippov, D.V., Blaser, H., Raz, E., Moens, C.B., Plasterk, R.H., Hannon, G.J., Draper, B.W., and Ketting, R.F. (2007) A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell. 129(1):69-82
Kuan, Y.S., Yu, H.H., Moens, C.B., and Halpern, M.E. (2007) Neuropilin asymmetry mediates a left-right difference in habenular connectivity. Development (Cambridge, England). 134(5):857-865
Erickson, T., Scholpp, S., Brand, M., Moens, C.B., and Waskiewicz, A. Jan (2007) Pbx proteins cooperate with Engrailed to pattern the midbrain-hindbrain and diencephalic-mesencephalic boundaries. Developmental Biology. 301(2):504-517
Hernandez, R.E., Putzke, A.P., Myers, J.P., Margaretha, L., and Moens, C.B. (2007) Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development. Development (Cambridge, England). 134(1):177-187
Moens, C.B., Draper, B.W., Donn, T., Mullenberg, J., and Wolf-Saxon, E. (2006) Submission and curation of data from a tilling mutagenesis screen. ZFIN Direct Data Submission.
Carmany-Rampey, A., and Moens, C.B. (2006) Modern mosaic analysis in the zebrafish. Methods (San Diego, Calif.). 39(3):228-238
Moens, C.B., and Selleri, L. (2006) Hox cofactors in vertebrate development. Developmental Biology. 291(2):193-206
Cooper, K.L., Armstrong, J., and Moens, C.B. (2005) Zebrafish foggy/spt5 is required for migration of facial branchiomotor neurons but not for their survival. Developmental dynamics : an official publication of the American Association of Anatomists. 234(3):651-658
Yu, H.H., and Moens, C.B. (2005) Semaphorin signaling guides cranial neural crest cell migration in zebrafish. Developmental Biology. 280(2):373-385
Cooke, J.E., Kemp, H.A., and Moens, C.B. (2005) EphA4 Is Required for Cell Adhesion and Rhombomere-Boundary Formation in the Zebrafish. Current biology : CB. 15(6):536-542
Hernandez, R.E., Rikhof, H.A., Bachmann, R., and Moens, C.B. (2004) vhnf1 integrates global RA patterning and local FGF signals to direct posterior hindbrain development in zebrafish. Development (Cambridge, England). 131(18):4511-4520
Yu, H.H., Houart, C., and Moens, C.B. (2004) Cloning and embryonic expression of zebrafish neuropilin genes. Gene expression patterns : GEP. 4(4):371-378
Draper, B.W., McCallum, C.M., Stout, J.L., Slade, A.J., and Moens, C.B. (2004) A high-throughput method for identifying N-ethyl-N-nitrosourea (ENU)-induced point mutations in zebrafish. The Zebrafish: Genetics, Genomics and Informatics, 2nd ed., Methods Cell Biol.. 77:91-112
Cooper, K.L., Leisenring, W.M., and Moens, C.B. (2003) Autonomous and nonautonomous functions for Hox/Pbx in branchiomotor neuron development. Developmental Biology. 253(2):200-213
Waskiewicz, A.J., Rikhof, H.A., and Moens, C.B. (2002) Eliminating zebrafish Pbx proteins reveals a hindbrain ground state. Developmental Cell. 3(5):723-733
Cooke, J.E. and Moens, C.B. (2002) Boundary formation in the hindbrain: Eph only it were simple. Trends in neurosciences. 25(5):260-267
Moens, C.B. and Prince, V.E. (2002) Constructing the hindbrain: Insights from the zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 224(1):1-17
Waskiewicz, A.J., Rikhof, H.A., Hernandez, R.E., and Moens, C.B. (2001) Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning. Development (Cambridge, England). 128(21):4139-4151
Gray, M., Moens, C.B., Amacher, S.L., Eisen, J.S., and Beattie, C.E. (2001) Zebrafish deadly seven functions in neurogenesis. Developmental Biology. 237(2):306-323
Kimmel, C.B., Miller, C.T., and Moens, C.B. (2001) Specification and morphogenesis of the zebrafish larval head skeleton. Developmental Biology. 233(2):239-257
Moens, C.B., Pöpperl, H., Waskiewicz, A., and Rikhof, H. (2001) Genetic control of hindbrain patterning in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15(5):A714
Cooke, J.E., Moens, C.B., Roth, L.W., Durbin, L., Shiomi, K., Brennan, C., Kimmel, C.B., Wilson, S.W., and Holder, N. (2001) Eph signalling functions downstream of Val to regulate cell sorting and boundary formation in the caudal hindbrain. Development (Cambridge, England). 128(4):571-580
Pöpperl, H., Rikhof, H., Chang, H., Haffter, P., Kimmel, C.B., and Moens, C.B. (2000) lazarus is a novel pbx gene that globally mediates Hox gene function in zebrafish. Molecular Cell. 6(2):255-267
Lekven, A.C., Helde, K.A., Thorpe, C.J., Rooke, R. and Moon, R.T. (2000) Reverse genetics in zebrafish. Physiological Genomics. 2:37-48
Sloop, K.W., Meier, B.C., Bridwell, J.L., Parker, G.E., Schiller, A.M., and Rhodes, S.J. (1999) Differential activation of pituitary hormone genes by human Lhx3 isoforms with distinct DNA binding properties. Molecular endocrinology (Baltimore, Md.). 13(12):2212-2225
Moens, C.B. and Fritz, A. (1999) Techniques in neural development. In The Zebrafish: Biology. H.W. Detrich, L.I. Zon, and M. Westerfield, eds. Methods Cell Biol.. 59:253-272
Ungar, A.R., Helde, K.A., and Moon, R.T. (1998) Production of androgenetic haploids in zebrafish with ultraviolet light. Molecular marine biology and biotechnology. 7:320-326
Moens, C.B., Cordes, S.P., Giorgianni, M.W., Barsh, G.S., and Kimmel, C.B, (1998) Equivalence in the genetic control of hindbrain segmentation in fish and mouse. Development (Cambridge, England). 125:381-391
Prince, V.E., Moens, C.B., Kimmel, C.B., and Ho, R.K. (1998) Zebrafish hox genes: expression in the hindbrain region of wild-type and mutants of the segmentation gene valentino. Development (Cambridge, England). 125:393-406
Chandrasekhar, A., Moens, C.B., Warren, J.T., Kimmel, C.B., and Kuwada, J.Y. (1997) Development of branchiomotor neurons in zebrafish. Development (Cambridge, England). 124(13):2633-2644
Schier, A.F., Neuhauss, S.C.F., Helde, K.A., Talbot, W.S., and Driever, W. (1997) The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development (Cambridge, England). 124(2):327-342
Moens, C.B., Yan, Y.L., Appel, B., Force, A.G., and Kimmel, C.B. (1996) valentino, a zebrafish gene required for normal hindbrain segmentation. Development (Cambridge, England). 122:3981-3990
Helde, K.A. (1995) Determinants of cell fate during zebrafish embryogenesis. Ph.D. Thesis.
Wilson, E.T., Cretekos, C.J., and Helde, K.A. (1995) Cell mixing during early epiboly in the zebrafish embryo. Developmental genetics. 17:6-15
Helde, K.A., Wilson, E.T., Cretekos, C.J., and Grunwald, D.J. (1994) Contribution of early cells to the fate map of the zebrafish gastrula. Science (New York, N.Y.). 265:517-520
Helde, K.A. and Grunwald, D.J. (1993) The DVR-1 (Vg1) transcript of zebrafish is maternally supplied and distributed throughout the embryo. Developmental Biology. 159:418-426
Wilson, E.T., Helde, K.A., and Grunwald, D.J. (1993) Something's fishy here--Rethinking cell movements and cell fate in the zebrafish embryo. Trends in genetics : TIG. 9:348-352
Helde, K. and Grunwald, D. (1992) The origin of cell diversity in zebrafish. Journal of cellular biochemistry. 16F:92