ZFIN Lab: Dirk Meyer Lab

ZFIN ID: ZDB-LAB-981215-1

Dirk Meyer Lab

PI/Director:	Meyer, Dirk
Co-PI / Senior Researcher:	Kimmel, Robin
Contact Person:	Meyer, Dirk
Email:	dirk.meyer@uibk.ac.at
URL:	http://www.uibk.ac.at/molbiol/
Address:	Institute of Molecular Biology Leopold-Franzens-University Innsbruck Technikerstr. 25 6020 Innsbruck Austria
Country:	Austria
Phone:	0043-(0)512-507-51410
Fax:	0043-(0)512-507-51499
Line Designation:	ml

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 32 genomic features

STATEMENT OF RESEARCH INTERESTS

Mesoderm formation and patterning, Pancreas development and regeneration.

LAB MEMBERS

Arkhipova, Valeriya Post-Doc	Fischer, Patrick Post-Doc	Wilfinger, Armin Post-Doc
Krautgasser, Claudia Graduate Student	Lorincz, Réka Graduate Student	Schmitner, Nicole Graduate Student
Tufegdzic, Dzenana Fish Facility Staff	Töchterle, Sonja Technical Staff	Baldemair, Caroline Administrative Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Graber, M., Nägele, F., Röhrs, B.T., Hirsch, J., Pölzl, L., Moriggl, B., Mayr, A., Troger, F., Kirchmair, E., Wagner, J.F., Nowosielski, M., Mayer, L., Voelkl, J., Tancevski, I., Meyer, D., Grimm, M., Knoflach, M., Holfeld, J., Gollmann-Tepeköylü, C. (2022) Prevention of Oxidative Damage in Spinal Cord Ischemia Upon Aortic Surgery: First-In-Human Results of Shock Wave Therapy Prove Safety and Feasibility. Journal of the American Heart Association. 11(20):e026076

Schmitner, N., Recheis, C., Thönig, J., Kimmel, R.A. (2021) Differential Responses of Neural Retina Progenitor Populations to Chronic Hyperglycemia. Cells. 10(11):

Casteels, T., Zhang, Y., Frogne, T., Sturtzel, C., Lardeau, C.H., Sen, I., Liu, X., Hong, S., Pauler, F.M., Penz, T., Brandstetter, M., Barbieux, C., Berishvili, E., Heuser, T., Bock, C., Riedel, C.G., Meyer, D., Distel, M., Hecksher-Sørensen, J., Li, J., Kubicek, S. (2021) An inhibitor-mediated beta cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation. Molecular metabolism. 54:101329

Tschaikner, P., Regele, D., Röck, R., Salvenmoser, W., Meyer, D., Bouvier, M., Geley, S., Stefan, E., Aanstad, P. (2021) Feedback Control of the Gpr161-G_αs-PKA axis contributes to basal Hedgehog repression in zebrafish. Development (Cambridge, England). 148(4):

Freudenblum, J., Meyer, D., Kimmel, R.A. (2020) Inducible Mosaic Cell Labeling Provides Insights Into Pancreatic Islet Morphogenesis. Frontiers in cell and developmental biology. 8:586651

Gollmann-Tepeköylü, C., Nägele, F., Graber, M., Pölzl, L., Lobenwein, D., Hirsch, J., An, A., Irschick, R., Röhrs, B., Kremser, C., Hackl, H., Huber, R., Venezia, S., Hercher, D., Fritsch, H., Bonaros, N., Stefanova, N., Tancevski, I., Meyer, D., Grimm, M., Holfeld, J. (2020) Shock waves promote spinal cord repair via TLR3. JCI insight. 5(15):

Ali, Z., Zang, J., Lagali, N., Schmitner, N., Salvenmoser, W., Mukwaya, A., Neuhauss, S.C.F., Jensen, L.D., Kimmel, R.A. (2020) Photoreceptor Degeneration Accompanies Vascular Changes in a Zebrafish Model of Diabetic Retinopathy. Investigative ophthalmology & visual science. 61:43

Fischer, P., Chen, H., Pacho, F., Rieder, D., Kimmel, R.A., Meyer, D. (2019) FoxH1 represses miR-430 during early embryonic development of zebrafish via non-canonical regulation. BMC Biology. 17:61

Emfinger, C.H., Lőrincz, R., Wang, Y., York, N.W., Singareddy, S.S., Ikle, J.M., Tryon, R.C., McClenaghan, C., Shyr, Z.A., Huang, Y., Reissaus, C.A., Meyer, D., Piston, D.W., Hyrc, K., Remedi, M.S., Nichols, C.G. (2019) Beta-cell excitability and excitability-driven diabetes in adult Zebrafish islets. Physiological Reports. 7:e14101

Lorincz, R., Emfinger, C.H., Walcher, A., Giolai, M., Krautgasser, C., Remedi, M.S., Nichols, C.G., Meyer, D. (2018) In vivo monitoring of intracellular Ca²⁺ dynamics in the pancreatic β-cells of zebrafish embryos. Islets. 10(6):221-238

Freudenblum, J., Iglesias, J.A., Hermann, M., Walsen, T., Wilfinger, A., Meyer, D., Kimmel, R.A. (2018) In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis.. Development (Cambridge, England). 145(3)

Facchinello, N., Tarifeño-Saldivia, E., Grisan, E., Schiavone, M., Peron, M., Mongera, A., Ek, O., Schmitner, N., Meyer, D., Peers, B., Tiso, N., Argenton, F. (2017) Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration. Scientific Reports. 7:9605

Schmitner, N., Kohno, K., Meyer, D. (2017) ptf1a⁺ , ela3l^- cells are developmentally maintained progenitors for exocrine regeneration following extreme loss of acinar cells in zebrafish larvae.. Disease models & mechanisms. 10(3):307-321

Li, J., Casteels, T., Frogne, T., Ingvorsen, C., Honoré, C., Courtney, M., Huber, K.V., Schmitner, N., Kimmel, R.A., Romanov, R.A., Sturtzel, C., Lardeau, C.H., Klughammer, J., Farlik, M., Sdelci, S., Vieira, A., Avolio, F., Briand, F., Baburin, I., Májek, P., Pauler, F.M., Penz, T., Stukalov, A., Gridling, M., Parapatics, K., Barbieux, C., Berishvili, E., Spittler, A., Colinge, J., Bennett, K.L., Hering, S., Sulpice, T., Bock, C., Distel, M., Harkany, T., Meyer, D., Superti-Furga, G., Collombat, P., Hecksher-Sørensen, J., Kubicek, S. (2017) Artemisinins Target GABA_A Receptor Signaling and Impair α Cell Identity.. Cell. 168(1-2):86-100.e15

Ott, E., Wendik, B., Srivastava, M., Pacho, F., Töchterle, S., Salvenmoser, W., Meyer, D. (2016) Pronephric tubule morphogenesis in zebrafish depends on Mnx mediated repression of irx1b within the intermediate mesoderm. Developmental Biology. 411(1):101-14

Kimmel, R.A., Meyer, D. (2016) Zebrafish pancreas as a model for development and disease. Methods in cell biology. 134:431-61

Krautgasser, C. (2016) Dysfunction of voltage-gated calcium channel Cav1.2 induces altered endocrine cell formation in Zebrafish embryos. Ph.D. Thesis.

Astone, M., Pizzi, M., Peron, M., Domenichini, A., Guzzardo, V., Töchterle, S., Tiso, N., Rugge, M., Meyer, D., Argenton, F., Vettori, A. (2015) A GFP-Tagged Gross Deletion on Chromosome 1 Causes Malignant Peripheral Nerve Sheath Tumors and Carcinomas in Zebrafish. PLoS One. 10:e0145178

Chen, H., Babino, D., Schoenbichler, S.A., Arkhipova, V., Töchterle, S., Martin, F., Huck, C.W., von Lintig, J., Meyer, D. (2015) Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7. PLoS One. 10:e0143825

Kimmel, R.A., Dobler, S., Schmitner, N., Walsen, T., Freudenblum, J., Meyer, D. (2015) Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment. Scientific Reports. 5:14241

Casari, A., Schiavone, M., Facchinello, N., Vettori, A., Meyer, D., Tiso, N., Moro, E., Argenton, F. (2014) A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development. Developmental Biology. 396(1):81-93

Liu, M., Schmitner, N., Sandrian, M.G., Zabihian, B., Hermann, B., Salvenmoser, W., Meyer, D., and Drexler, W. (2013) In vivo three dimensional dual wavelength photoacoustic tomography imaging of the far red fluorescent protein E2-Crimson expressed in adult zebrafish. Biomedical Optics Express. 4(10):1846-1855

Nuster, R., Schmitner, N., Wurzinger, G., Gratt, S., Salvenmoser, W., Meyer, D., and Paltauf, G. (2013) Hybrid photoacoustic and ultrasound section imaging with optical ultrasound detection. Journal of biophotonics. 6(6-7):549-559

Wilfinger, A., Arkhipova, V., and Meyer, D. (2013) Cell type and tissue specific function of islet genes in zebrafish pancreas development. Developmental Biology. 378(1):25-37

Dumortier, J.G., Martin, S., Meyer, D., Rosa, F.M., and David, N.B. (2012) Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts. Proceedings of the National Academy of Sciences of the United States of America. 109(42):16945-16950

Arkhipova, V., Wendik, B., Devos, N., Ek, O., Peers, B., and Meyer, D. (2012) Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish. Developmental Biology. 365(1):290-302

Voz, M.L., Coppieters, W., Manfroid, I., Baudhuin, A., Von Berg, V., Charlier, C., Meyer, D., Driever, W., Martial, J.A., and Peers, B. (2012) Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Induced Mutation by Whole-Genome Sequencing. PLoS One. 7(4):e34671

Untergasser, G., Martowicz, A., Hermann, M., Töchterle, S., and Meyer, D. (2011) Distinct expression patterns of dickkopf genes during late embryonic development of Danio rerio. Gene expression patterns : GEP. 11(8):491-500

Kimmel, R.A., Onder, L., Wilfinger, A., Ellertsdottir, E., and Meyer, D. (2011) Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish. BMC Biology. 9(1):75

Kimmel, R.A., and Meyer, D. (2010) Chapter 10 - Molecular regulation of pancreas development in zebrafish. Methods in cell biology. 100:261-280

Feldner, J., Reimer, M.M., Schweitzer, J., Wendik, B., Meyer, D., Becker, T., and Becker, C.G. (2007) PlexinA3 restricts spinal exit points and branching of trunk motor nerves in embryonic zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(18):4978-4983

Epting, D., Vorwerk, S., Hageman, A., and Meyer, D. (2007) Expression of rasgef1b in zebrafish. Gene expression patterns : GEP. 7(4):389-395

Flanagan-Steet, H., Fox, M.A., Meyer, D., and Sanes, J.R. (2005) Neuromuscular synapses can form in vivo by incorporation of initially aneural postsynaptic specializations. Development (Cambridge, England). 132(20):4471-4481

Wendik, B., Maier, E., and Meyer, D. (2004) Zebrafish mnx genes in endocrine and exocrine pancreas formation. Developmental Biology. 268(2):372-383

Zecchin, E., Mavropoulos, A., Devos, N., Filippi, A., Tiso, N., Meyer, D., Peers, B., Bortolussi, M., Argenton, F. (2004) Evolutionary conserved role of ptf1a in the specification of exocrine pancreatic fates. Developmental Biology. 268(1):174-184

Deflorian, G., Tiso, N., Ferretti, E., Meyer, D., Blasi, F., Bortolussi, M., and Argenton, F. (2004) Prep1.1 has essential genetic functions in hindbrain development and cranial neural crest cell differentiation. Development (Cambridge, England). 131(3):613-627

Gnügge, L., Meyer, D., and Driever, W. (2004) Pancreas development in zebrafish. The Zebrafish: Cellular and Developmental Biology,2nd Ed. Methods Cell Biol.. 76:531-551

Trinh, L.A., Meyer, D., and Stainier, D.Y. (2003) The Mix family homeodomain gene bonnie and clyde functions with other components of the Nodal signaling pathway to regulate neural patterning in zebrafish. Development (Cambridge, England). 130(20):4989-4998

Yoda, H., Momoi, A., Esguerra, C.V., Meyer, D., Driever, W., Kondoh, H., and Furutani-Seiki, M. (2003) An expression pattern screen for genes involved in the induction of the posterior nervous system of zebrafish. Differentiation; research in biological diversity. 71(2):152-162

Doitsidou, M., Reichman-Fried, M., Stebler, J., Köprunner, M., Dörries, J., Meyer, D., Esguerra, C.V., Leung, T., and Raz, E. (2002) Guidance of primordial germ cell migration by the chemokine SDF-1. Cell. 111(5):647-659

Pogoda, H.M. and Meyer, D. (2002) Zebrafish smad7 is regulated by Smad3 and BMP signals. Developmental Dynamics : an official publication of the American Association of Anatomists. 224(3):334-349

Belting, H.G., Hauptmann, G., Meyer, D., Abdelilah-Seyfried, S., Chitnis, A., Eschbach, C., Söll, I., Thisse, C., Thisse, B., Artinger, K., Lunde, K., and Driever, W. (2001) spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer. Development (Cambridge, England). 128(21):4165-4176

Pogoda, H.M., Solnica-Krezel, L., Driever, W., and Meyer, D. (2000) The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of Nodal signaling required for organizer formation. Current biology : CB. 10(17):1041-1049

Zhang, Q., Yaniv, K., Oberman, F., Wolke, U., Git, A., Fromer, M., Taylor, W.L., Meyer, D., Standart, N., Raz, E., and Yisraeli, J.K. (1999) Vg1 RBP intracellular distribution and evolutionarily conserved expression at multiple stages during development. Mechanisms of Development. 88(1):101-106

Driever, W., Solnica-Krezel, L., Abdelilah, S., Meyer, D., and Stemple, D. (1997) Genetic analysis of pattern formation in the zebrafish neural plate. Cold Spring Harbor symposia on quantitative biology. 62:523-534