ZFIN ID: ZDB-LAB-980602-3
Crosier Lab
PI/Director: Crosier, Kathy
Crosier, Phil
Co-PI / Senior
Researcher:		 Flores, Maria
Horsfield, Jules
Contact Person: Crosier, Phil
Email: ps.crosier@auckland.ac.nz
URL:
Address: Department of Molecular Medicine University of Auckland School of Medicine Private Bag Auckland, 92019 New Zealand
Country: New Zealand
Phone: 64-9-373-7599 ext. 86279
Fax: 64-9-373-7010
Line Designation: nz


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 14 genomic features


STATEMENT OF RESEARCH INTERESTS
Our laboratory works in the areas of hematopoiesis, vasculogenesis and immunity. We have a particular interest in the Runx family of transcription factors and are investigating their roles in developmental processes and disease. A genetic screen looking for modifiers of Runx1 expression has been undertaken and we are continuing to work on a model of RUNX1-ETO leukemia developed in our laboratory. Investigations are also directed at understanding the gut immune system and opening up opportunities to further understanding of inflammatory bowel disorders.


LAB MEMBERS
Astin, Jonathan Post-Doc Hall, Chris Post-Doc Kamei, Makoto Post-Doc
Lam, Enid Graduate Student Storm, Thilo Graduate Student Mahagaonkar, Alhad Fish Facility Staff
Oehlers, Stefan Fish Facility Staff Chien, Annie Technical Staff Fluhler, Wendy Technical Staff
Pullin, Lisa Technical Staff Crawford, Katie Administrative Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Stayner, C., Poole, C.A., McGlashan, S.R., Pilanthananond, M., Brauning, R., Markie, D., Lett, B., Slobbe, L., Chae, A., Johnstone, A.C., Jensen, C.G., McEwan, J.C., Dittmer, K., Parker, K., Wiles, A., Blackburne, W., Leichter, A., Leask, M., Pinnapureddy, A., Jennings, M., Horsfield, J.A., Walker, R.J., Eccles, M.R. (2017) An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations. Scientific Reports. 7:1601
Hasegawa, T., Hall, C.J., Crosier, P.S., Abe, G., Kawakami, K., Kudo, A., Kawakami, A. (2017) Transient inflammatory response mediated by interleukin-1β is required for proper regeneration in zebrafish fin fold. eLIFE. 6
Oehlers, S.H., Flores, M.V., Hall, C.J., Wang, L., Ko, D.C., Crosier, K.E., Crosier, P.S. (2016) A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation. The FEBS journal.
Fehr, A.G., Ruetten, M., Seth-Smith, H.M., Nufer, L., Voegtlin, A., Lehner, A., Greub, G., Crosier, P.S., Neuhauss, S.C., Vaughan, L. (2016) A Zebrafish Model for Chlamydia Infection with the Obligate Intracellular Pathogen Waddlia chondrophila. Frontiers in microbiology. 7:1829
Dalton, J.P., Uy, B., Okuda, K.S., Hall, C.J., Denny, W.A., Crosier, P.S., Swift, S., Wiles, S. (2016) Screening of anti-mycobacterial compounds in a naturally infected zebrafish larvae model. The Journal of antimicrobial chemotherapy. 72(2):421-427
Cronan, M.R., Beerman, R.W., Rosenberg, A.F., Saelens, J.W., Johnson, M.G., Oehlers, S.H., Sisk, D.M., Jurcic Smith, K.L., Medvitz, N.A., Miller, S.E., Trinh, L.A., Fraser, S.E., Madden, J.F., Turner, J., Stout, J.E., Lee, S., Tobin, D.M. (2016) Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection. Immunity. 45:861-876
Astin, J.W., Keerthisinghe, P., Du, L., Sanderson, L.E., Crosier, K.E., Crosier, P.S., Hall, C.J. (2016) Innate immune cells and bacterial infection in zebrafish. Methods in cell biology. 138:31-60
Oehlers, S.H., Cronan, M.R., Beerman, R.W., Johnson, M.G., Huang, J., Kontos, C.D., Stout, J.E., Tobin, D.M. (2016) Infection-induced vascular permeability aids mycobacterial growth. The Journal of infectious diseases. 215(5):813-817
Matty, M.A., Oehlers, S.H., Tobin, D.M. (2016) Live Imaging of Host-Pathogen Interactions in Zebrafish Larvae. Methods in molecular biology (Clifton, N.J.). 1451:207-23
Astin, J.W., Crosier, P.S. (2016) Lymphatics, Cancer and Zebrafish. Advances in experimental medicine and biology. 916:199-218
Jung, H.M., Isogai, S., Kamei, M., Castranova, D., Gore, A.V., Weinstein, B.M. (2016) Imaging blood vessels and lymphatic vessels in the zebrafish. Methods in cell biology. 133:69-103
Castranova, D., Davis, A.E., Lo, B.D., Miller, M.F., Paukstelis, P.J., Swift, M.R., Pham, V.N., Torres-Vázquez, J., Bell, K., Shaw, K.M., Kamei, M., Weinstein, B.M. (2016) Aminoacyl-Transfer RNA Synthetase Deficiency Promotes Angiogenesis via the Unfolded Protein Response Pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 36(4):655-62
Oliver, V.F., van Bysterveldt, K.A., Cadzow, M., Steger, B., Romano, V., Markie, D., Hewitt, A.W., Mackey, D.A., Willoughby, C.E., Sherwin, T., Crosier, P.S., McGhee, C.N., Vincent, A.L. (2016) A COL17A1 Splice-Altering Mutation Is Prevalent in Inherited Recurrent Corneal Erosions. Ophthalmology. 123(4):709-22
Ulrich, F., Carretero-Ortega, J., Menéndez, J., Narvaez, C., Sun, B., Lancaster, E., Pershad, V., Trzaska, S., Véliz, E., Kamei, M., Prendergast, A., Kidd, K.R., Shaw, K.M., Castranova, D.A., Pham, V.N., Lo, B.D., Martin, B.L., Raible, D.W., Weinstein, B.M., Torres-Vazquez, J. (2015) Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development (Cambridge, England). 143(1):147-59
Macdonald, N.P., Zhu, F., Hall, C.J., Reboud, J., Crosier, P.S., Patton, E.E., Wlodkowic, D., Cooper, J.M. (2015) Assessment of biocompatibility of 3D printed photopolymers using zebrafish embryo toxicity assays. Lab on a Chip. 16(2):291-7
Hall, C., Crosier, P., Crosier, K. (2015) Inflammatory cytokines provide both infection-responsive and developmental signals for blood development: Lessons from the zebrafish. Molecular immunology. 69:113-22
Cronan, M.R., Rosenberg, A.F., Oehlers, S.H., Saelens, J.W., Sisk, D.M., Smith, K.L., Lee, S., Tobin, D.M. (2015) CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections. Disease models & mechanisms. 8(12):1643-50
Schuster, K., Leeke, B., Meier, M., Wang, Y., Newman, T., Burgess, S., Horsfield, J.A. (2015) A neural crest origin for cohesinopathy heart defects. Human Molecular Genetics. 24(24):7005-16
Tenor, J.L., Oehlers, S.H., Yang, J.L., Tobin, D.M., Perfect, J.R. (2015) Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion. mBio. 6(5):e01425-15
Wang, L., Oehlers, S.H., Espenschied, S.T., Rawls, J.F., Tobin, D.M., Ko, D.C. (2015) CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation. Genome biology. 16:190
Okuda, K.S., Misa, J.P., Oehlers, S.H., Hall, C.J., Ellett, F., Alasmari, S., Lieschke, G.J., Crosier, K.E., Crosier, P.S., Astin, J.W. (2015) A zebrafish model of inflammatory lymphangiogenesis. Biology Open. 4(10):1270-80
Koltowska, K., Paterson, S., Bower, N.I., Baillie, G.J., Lagendijk, A.K., Astin, J.W., Chen, H., Francois, M., Crosier, P.S., Taft, R.J., Simons, C., Smith, K.A., Hogan, B.M. (2015) mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish. Genes & Development. 29:1618-30
Zhu, F., Hall, C.J., Crosier, P.S., Wlodkowic, D. (2015) Interfacing Lab-on-a-Chip Embryo Technology with High-Definition Imaging Cytometry. Zebrafish. 12(4):315-8
Sanderson, L.E., Chien, A.T., Astin, J.W., Crosier, K.E., Crosier, P.S., Hall, C.J. (2015) An inducible transgene reports activation of macrophages in live zebrafish larvae. Developmental and comparative immunology. 53(1):63-9
Chew, T.S., O'Shea, N.R., Sewell, G.W., Oehlers, S.H., Mulvey, C.M., Crosier, P.S., Godovac-Zimmermann, J., Bloom, S.L., Smith, A.M., Segal, A.W. (2015) Optineurin deficiency contributes to impaired cytokine secretion and neutrophil recruitment in bacteria driven colitis. Disease models & mechanisms. 8(8):817-29
Nicenboim, J., Malkinson, G., Lupo, T., Asaf, L., Sela, Y., Mayseless, O., Gibbs-Bar, L., Senderovich, N., Hashimshony, T., Shin, M., Jerafi-Vider, A., Avraham-Davidi, I., Krupalnik, V., Hofi, R., Almog, G., Astin, J.W., Golani, O., Ben-Dor, S., Crosier, P.S., Herzog, W., Lawson, N.D., Hanna, J.H., Yanai, I., Yaniv, K. (2015) Lymphatic vessels arise from specialized angioblasts within a venous niche. Nature. 522(7554):56-61
Akagi, J., Zhu, F., Skommer, J., Hall, C.J., Crosier, P.S., Cialkowski, M., Wlodkowic, D. (2014) Microfluidic device for a rapid immobilization of Zebrafish larvae in environmental scanning electron microscopy. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 87(3):190-4
Oehlers, S.H., Cronan, M.R., Scott, N.R., Thomas, M.I., Okuda, K.S., Walton, E.M., Beerman, R.W., Crosier, P.S., Tobin, D.M. (2014) Interception of host angiogenic signalling limits mycobacterial growth. Nature. 517(7536):612-5
Hall, C.J., Sanderson, L.E., Crosier, K.E., Crosier, P.S. (2014) Mitochondrial metabolism, reactive oxygen species, and macrophage function-fishing for insights. J. Mol. Med.. 92(11):1119-28
Kartopawiro, J., Bower, N.I., Karnezis, T., Kazenwadel, J., Betterman, K.L., Lesieur, E., Koltowska, K., Astin, J., Crosier, P., Vermeren, S., Achen, M.G., Stacker, S.A., Smith, K.A., Harvey, N.L., François, M., and Hogan, B.M. (2014) Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development. Hum. Mol. Genet.. 23(5):1286-97
Zhu, F., Skommer, J., Huang, Y., Akagi, J., Adams, D., Levin, M., Hall, C.J., Crosier, P.S., Wlodkowic, D. (2014) Fishing on chips: Up-and-coming technological advances in analysis of zebrafish and Xenopus embryos. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 85(11):921-32
Astin, J.W., Jamieson, S.M., Eng, T.C., Flores, M.V., Misa, J.P., Chien, A., Crosier, K.E., Crosier, P.S. (2014) An In Vivo Antilymphatic Screen in Zebrafish Identifies Novel Inhibitors of Mammalian Lymphangiogenesis and Lymphatic-Mediated Metastasis. Molecular cancer therapeutics. 13(10):2450-62
Hall, C.J., Wicker, S.M., Chien, A.T., Tromp, A., Lawrence, L.M., Sun, X., Krissansen, G.W., Crosier, K.E., Crosier, P.S. (2014) Repositioning drugs for inflammatory disease-fishing for new anti-inflammatory agents. Disease models & mechanisms. 7(9):1069-81
Astin, J.W., Haggerty, M.J., Okuda, K.S., Le Guen, L., Misa, J.P., Tromp, A., Hogan, B.M., Crosier, K.E., Crosier, P.S. (2014) Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting. Development (Cambridge, England). 141(13):2680-90
Hall, C.J., Boyle, R.H., Sun, X., Wicker, S.M., Misa, J.P., Krissansen, G.W., Print, C.G., Crosier, K.E., Crosier, P.S. (2014) Epidermal cells help coordinate leukocyte migration during inflammation through fatty acid-fuelled matrix metalloproteinase production. Nature communications. 5:3880
Coxam, B., Sabine, A., Bower, N.I., Smith, K.A., Pichol-Thievend, C., Skoczylas, R., Astin, J.W., Frampton, E., Jaquet, M., Crosier, P.S., Parton, R.G., Harvey, N.L., Petrova, T.V., Schulte-Merker, S., Francois, M., Hogan, B.M. (2014) Pkd1 Regulates Lymphatic Vascular Morphogenesis during Development. Cell Reports. 7:623-33
Akagi, J., Zhu, F., Hall, C.J., Crosier, K.E., Crosier, P.S., Wlodkowic, D. (2014) Integrated chip-based physiometer for automated fish embryo toxicity biotests in pharmaceutical screening and ecotoxicology. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 85(6):537-47
Kline, A.D., Calof, A.L., Schaaf, C.A., Krantz, I.D., Jyonouchi, S., Yokomori, K., Gauze, M., Carrico, C.S., Woodman, J., Gerton, J.L., Vega, H., Levin, A.V., Shirahige, K., Champion, M., Goodban, M.T., O'Connor, J.T., Pipan, M., Horsfield, J., Deardorff, M.A., Ishman, S.L., and Dorsett, D. (2014) Cornelia de Lange syndrome: Further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts. American journal of medical genetics. Part A. 164(6):1384-93
Akagi, J., Hall, C.J., Crosier, K.E., Cooper, J.M., Crosier, P.S., and Wlodkowic, D. (2014) OpenSource lab-on-a-chip physiometer for accelerated zebrafish embryo biotests. Current Protocols Cytometry. 67:Unit 9.44
Marsman, J., O'Neill, A.C., Kao, B.R., Rhodes, J.M., Meier, M., Antony, J., Mönnich, M., and Horsfield, J.A. (2014) Cohesin and CTCF differentially regulate spatiotemporal runx1 expression during zebrafish development. BBA Gene Regulatory Mechanisms. 1839(1):50-61
Hall, C.J., Boyle, R.H., Astin, J.W., Flores, M.V., Oehlers, S.H., Sanderson, L.E., Ellett, F., Lieschke, G.J., Crosier, K.E., and Crosier, P.S. (2013) Immunoresponsive Gene 1 Augments Bactericidal Activity of Macrophage-Lineage Cells by Regulating β-Oxidation-Dependent Mitochondrial ROS Production. Cell Metabolism. 18(2):265-278
Wilson, C.W., Parker, L.H., Hall, C.J., Smyczek, T., Mak, J., Crow, A., Posthuma, G., De Mazière, A., Sagolla, M., Chalouni, C., Vitorino, P., Roose-Girma, M., Warming, S., Klumperman, J., Crosier, P.S., and Ye, W. (2013) Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood.. 122(22):3678-90
Chatterjee, A., Ozaki, Y., Stockwell, P.A., Horsfield, J.A., Morison, I.M., and Nakagawa, S. (2013) Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing. Epigenetics. 8(9):979-89
Wang, K.I., Salcic, Z., Yeh, J., Akagi, J., Zhu, F., Hall, C.J., Crosier, K.E., Crosier, P.S., and Wlodkowic, D. (2013) Toward embedded laboratory automation for smart lab-on-a-chip embryo arrays. Biosensors and Bioelectronics. 48C:188-196
Oehlers, S.H., Flores, M.V., Hall, C.J., Okuda, K.S., Sison, J.O., Crosier, K.E., and Crosier, P.S. (2013) Chemically Induced Intestinal Damage Models in Zebrafish Larvae. Zebrafish. 10(2):184-93
Pase, L., Layton, J.E., Wittmann, C., Ellett, F., Nowell, C.J., Reyes-Aldasoro, C.C., Varma, S., Rogers, K.L., Hall, C.J., Keightley, M.C., Crosier, P.S., Grabher, C., Heath, J.K., Renshaw, S.A., and Lieschke, G.J. (2012) Neutrophil-Delivered Myeloperoxidase Dampens the Hydrogen Peroxide Burst after Tissue Wounding in Zebrafish. Current biology : CB. 22(19):1818-1824
Berman, J., Payne, E., and Hall, C. (2012) The zebrafish as a tool to study hematopoiesis, human blood diseases, and immune function. Advances in hematology. 2012:425345
Yang, C.T., Cambier, C.J., Davis, J.M., Hall, C.J., Crosier, P.S., and Ramakrishnan, L. (2012) Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages. Cell Host & Microbe. 12(3):301-312
Horsfield, J.A., Print, C.G., and Mönnich, M. (2012) Diverse developmental disorders from the one ring: distinct molecular pathways underlie the cohesinopathies. Frontiers in Epigenomics. 3:171
Pan, W., Pham, V.N., Stratman, A.N., Castranova, D., Kamei, M., Kidd, K.R., Lo, B.D., Shaw, K.M., Torres-Vazquez, J., Mikelis, C.M., Gutkind, J.S., Davis, G.E., and Weinstein, B.M. (2012) CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis. Blood.. 120(2):489-498
Oehlers, S.H., Flores, M.V., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2012) Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis. Disease models & mechanisms. 5(4):457-467
Okuda, K.S., Astin, J.W., Misa, J.P., Flores, M.V., Crosier, K.E., and Crosier, P.S. (2012) lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish. Development (Cambridge, England). 139(13):2381-2391
Khoshmanesh, K., Akagi, J., Hall, C.J., Crosier, K.E., Crosier, P.S., Cooper, J.M., and Wlodkowic, D. (2012) New rationale for large metazoan embryo manipulations on chip-based devices. Biomicrofluidics. 6(2):24102-2410214
Akagi, J., Khoshmanesh, K., Evans, B., Hall, C.J., Crosier, K.E., Cooper, J.M., Crosier, P.S., and Wlodkowic, D. (2012) Miniaturized Embryo Array for Automated Trapping, Immobilization and Microperfusion of Zebrafish Embryos. PLoS One. 7(5):e36630
Hall, C.J., Flores, M.V., Oehlers, S.H., Sanderson, L.E., Lam, E.Y., Crosier, K.E., and Crosier, P.S. (2012) Infection-Responsive Expansion of the Hematopoietic Stem and Progenitor Cell Compartment in Zebrafish Is Dependent upon Inducible Nitric Oxide. Cell Stem Cell. 10(2):198-209
Buchanan, C.M., Shih, J.H., Astin, J.W., Rewcastle, G.W., Flanagan, J.U., Crosier, P.S., and Shepherd, P.R. (2011) DMXAA (Vadimezan, ASA404) is a Multi-kinase Inhibitor Targetting VEGF-R2 in Particular. Clinical Science (London). 122(10):449-457
Valdivia, L.E., Young, R.M., Hawkins, T.A., Stickney, H.L., Cavodeassi, F., Schwarz, Q., Pullin, L.M., Villegas, R., Moro, E., Argenton, F., Allende, M.L., and Wilson, S.W. (2011) Lef1-dependent Wnt/β-catenin signalling drives the proliferative engine that maintains tissue homeostasis during lateral line development. Development (Cambridge, England). 138(18):3931-3941
Oehlers, S.H., Flores, M.V., Hall, C.J., Swift, S., Crosier, K.E., and Crosier, P.S. (2011) The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish. Disease models & mechanisms. 4(6):832-41
Mönnich, M., Kuriger, Z., Print, C.G., and Horsfield, J.A. (2011) A zebrafish model of Roberts syndrome reveals that Esco2 depletion interferes with development by disrupting the cell cycle. PLoS One. 6(5):e20051
Crawford, K.C., Flores, M.V., Oehlers, S.H., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2011) Zebrafish heat shock protein a4 genes in the intestinal epithelium are up-regulated during inflammation. Genesis (New York, N.Y. : 2000). 49(12):905-11
Oehlers, S.H., Flores, M.V., Chen, T., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2011) Topographical distribution of antimicrobial genes in the zebrafish intestine. Developmental and comparative immunology. 35(3):385-391
Oehlers, S.H., Flores, M.V., Okuda, K.S., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2011) A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents. Developmental dynamics : an official publication of the American Association of Anatomists. 240(1):288-298
Kamei, M., Isogai, S., Pan, W., and Weinstein, B.M. (2010) Chapter 2 - Imaging blood vessels in the zebrafish. Meth. Cell. Biol.. 100:27-54
Flores, M.V., Crawford, K.C., Pullin, L.M., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2010) Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties. Biochemical and Biophysical Research Communications. 400(1):164-168
Rhodes, J.M., Bentley, F.K., Print, C.G., Dorsett, D., Misulovin, Z., Dickinson, E.J., Crosier, K.E., Crosier, P.S., and Horsfield, J.A. (2010) Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved. Developmental Biology. 344(2):637-649
Lam, E.Y., Hall, C.J., Crosier, P.S., Crosier, K.E., and Flores, M.V. (2010) Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells. Blood.. 116(6):909-914
Flores, M.V., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2010) Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologies. Developmental dynamics : an official publication of the American Association of Anatomists. 239(7):2128-2135
Oehlers, S.H., Flores, M.V., Hall, C.J., O'Toole, R., Swift, S., Crosier, K.E., and Crosier, P.S. (2010) Expression of zebrafish cxcl8 (interleukin-8) and its receptors during development and in response to immune stimulation. Developmental and comparative immunology. 34(3):352-359
Mönnich, M., Banks, S., Eccles, M., Dickinson, E., and Horsfield, J. (2009) Expression of cohesin and condensin genes during zebrafish development supports a non-proliferative role for cohesin. Gene Expression Patterns. 9(8):586-594
Brannon, M.K., Davis, J.M., Mathias, J.R., Hall, C.J., Emerson, J.C., Crosier, P.S., Huttenlocher, A., Ramakrishnan, L., and Moskowitz, S.M. (2009) Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos. Cellular Microbiology. 11(5):755-768
Hall, C., Flores, M.V., Chien, A., Davidson, A., Crosier, K., and Crosier, P. (2009) Transgenic zebrafish reporter lines reveal conserved Toll-like receptor signaling potential in embryonic myeloid leukocytes and adult immune cell lineages. Journal of Leukocyte Biology. 85(5):751-765
Stoletov, K., Fang, L., Choi, S.H., Hartvigsen, K., Hansen, L.F., Hall, C., Pattison, J., Juliano, J., Miller, E.R., Almazan, F., Crosier, P., Witztum, J.L., Klemke, R.L., and Miller, Y.I. (2009) Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish. Circulation research. 104(8):952-960
Liongue, C., Hall, C.J., O'Connell, B.A., Crosier, P., and Ward, A.C. (2009) Zebrafish granulocyte colony-stimulating factor receptor signaling promotes myelopoiesis and myeloid cell migration. Blood.. 113(11):2535-2546
Lam, E.Y., Chau, J.Y., Kalev-Zylinska, M.L., Fountaine, T.M., Mead, R.S., Hall, C.J., Crosier, P.S., Crosier, K.E., and Flores, M.V. (2009) Zebrafish runx1 promoter-EGFP transgenics mark discrete sites of definitive blood progenitors. Blood.. 113(6):1241-1249
Hall, C., Flores, M.V., Crosier, K., and Crosier, P. (2009) Live cell imaging of zebrafish leukocytes. Meth. Mol. Biol.. 546:255-271
Lam, E.Y.N. (2009) Regulation of stem cell devleopment by runx transcription factors. Ph.D. Thesis. :239p
Storm, T. (2009) The intestinal inflammatory response to bacterial challenge with respect to the toll-like receptor signaling pathway in the zebrafish. Master's Thesis. :134p
Hall, C.J., Flores, M.V., Crosier, K.E., and Crosier, P.S. (2008) Live imaging early immune cell ontogeny and function in zebrafish Danio rerio. Journal of Fish Biology. 73(8):1833-1871
Flores, M.V., Hall, C.J., Davidson, A.J., Singh, P.P., Mahagaonkar, A.A., Zon, L.I., Crosier, K.E., and Crosier, P.S. (2008) Intestinal Differentiation in Zebrafish Requires Cdx1b, a Functional Equivalent of Mammalian Cdx2. Gastroenterology. 135(5):1665-1675
Cvejic, A., Hall, C., Bak-Maier, M., Flores, M.V., Crosier, P., Redd, M.J., and Martin, P. (2008) Analysis of WASp function during the wound inflammatory response - live-imaging studies in zebrafish larvae. Journal of Cell Science. 121(Pt 19):3196-3206
Aleström, P., Begemann, G., Carvan, M.J. 3rd, Cheng, K.C., Crosier, K., Crosier, P., Ekker, S., Huttenlocher, A., Kawakami, K., Kelly, G., Korzh, V., Lieschke, G., Mione, M., Neely, M.N., Neuhauss, S., and Trede, N.S. (2008) Views on four key questions about zebrafish research. Zebrafish. 5(1):9-24
Flores, M.V., Lam, E.Y., Crosier, K.E., and Crosier, P.S. (2008) Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish. Nat. Cell Biol.. 10(3):346-352
Buchner, D.A., Su, F., Yamaoka, J.S., Kamei, M., Shavit, J.A., Barthel, L.K., McGee, B., Amigo, J.D., Kim, S., Hanosh, A.W., Jagadeeswaran, P., Goldman, D., Lawson, N.D., Raymond, P.A., Weinstein, B.M., Ginsburg, D., and Lyons, S.E. (2007) pak2a mutations cause cerebral hemorrhage in redhead zebrafish. Proc. Natl. Acad. Sci. USA. 104(35):13996-140001
Horsfield, J.A., Anagnostou, S.H., Hu, J.K., Cho, K.H., Geisler, R., Lieschke, G., Crosier, K.E., and Crosier, P.S. (2007) Cohesin-dependent regulation of Runx genes. Development (Cambridge, England). 134(14):2639-2649
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