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Research
General Information
ZIRC
ZFIN ID: ZDB-LAB-980602-3
Crosier Lab
PI/Director: Crosier, Kathy
Crosier, Phil
Co-PI / Senior
Researcher:
Flores, Maria
Horsfield, Jules
Contact Person: Crosier, Phil
Email: ps.crosier@auckland.ac.nz
URL:
Address: Department of Molecular Medicine University of Auckland School of Medicine Private Bag Auckland, 92019 New Zealand
Country: New Zealand
Phone: 64-9-373-7599 ext. 86279
Fax: 64-9-373-7010
Line Designation: nz


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 14 genomic features


STATEMENT OF RESEARCH INTERESTS
Our laboratory works in the areas of hematopoiesis, vasculogenesis and immunity. We have a particular interest in the Runx family of transcription factors and are investigating their roles in developmental processes and disease. A genetic screen looking for modifiers of Runx1 expression has been undertaken and we are continuing to work on a model of RUNX1-ETO leukemia developed in our laboratory. Investigations are also directed at understanding the gut immune system and opening up opportunities to further understanding of inflammatory bowel disorders.


LAB MEMBERS
Astin, Jonathan Post-Doc Hall, Chris Post-Doc Kamei, Makoto Post-Doc
Lam, Enid Graduate Student Storm, Thilo Graduate Student Mahagaonkar, Alhad Fish Facility Staff
Chien, Annie Technical Staff Fluhler, Wendy Technical Staff Pullin, Lisa Technical Staff
Crawford, Katie Administrative Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Horsfield, J.A. (2019) Packaging development: how chromatin controls transcription in zebrafish embryogenesis. Biochemical Society transactions. 47(2):713-724
Eng, T.C., Chen, W., Okuda, K.S., Misa, J.P., Padberg, Y., Crosier, K.E., Crosier, P.S., Hall, C.J., Schulte-Merker, S., Hogan, B.M., Astin, J.W. (2019) Zebrafish facial lymphatics develop through sequential addition of venous and non-venous progenitors. EMBO reports. 20(5):
Wu, Z., Koh, B., Lawrence, L.M., Kanamala, M., Pool, B., Svirskis, D., Dalbeth, N., Astin, J.W., Crosier, K.E., Crosier, P.S., Hall, C.J. (2019) Liposome-Mediated Drug Delivery in Larval Zebrafish to Manipulate Macrophage Function. Zebrafish. 16(2):171-181
Leask, M., Dowdle, A., Salvesen, H., Topless, R., Fadason, T., Wei, W., Schierding, W., Marsman, J., O'Sullivan, J.M., Merriman, T.R., Horsfield, J.A. (2019) Functional Urate-Associated Genetic Variants Influence Expression of lincRNAs LINC01229 and MAFTRR. Frontiers in genetics. 9:733
Britto, D.D., Wyroba, B., Chen, W., Lockwood, R.A., Tran, K.B., Shepherd, P.R., Hall, C.J., Crosier, K.E., Crosier, P.S., Astin, J.W. (2018) Macrophages enhance Vegfa-driven angiogenesis in an embryonic zebrafish tumour xenograft model. Disease models & mechanisms. 11(12):
Ketharnathan, S., Leask, M., Boocock, J., Phipps-Green, A.J., Antony, J., O'Sullivan, J.M., Merriman, T.R., Horsfield, J.A. (2018) A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression. Human molecular genetics. 27(22):3964-3973
Cukrov, D., Newman, T., Leask, M., Leeke, B., Sarogni, P., Patimo, A., Kline, A.D., Krantz, I.D., Horsfield, J., Musio, A. (2018) Antioxidant treatment ameliorates phenotypic features of SMC1A-mutated Cornelia de Lange syndrome in vitro and in vivo. Human molecular genetics. 27(17):3002-3011
Hall, C.J., Sanderson, L.E., Lawrence, L.M., Pool, B., van der Kroef, M., Ashimbayeva, E., Britto, D., Harper, J.L., Lieschke, G.J., Astin, J.W., Crosier, K.E., Dalbeth, N., Crosier, P.S. (2018) Blocking fatty acid-fueled mROS production within macrophages alleviates acute gouty inflammation. The Journal of Clinical Investigation. 128(5):1752-1771
Eng, T.C.Y., Astin, J.W. (2018) Characterization of Zebrafish Facial Lymphatics. Methods in molecular biology (Clifton, N.J.). 1846:71-83
Lee, S.L.J., Horsfield, J.A., Black, M.A., Rutherford, K., Gemmell, N.J. (2017) Identification of sex differences in zebrafish (Danio rerio) brains during early sexual differentiation and masculinisation using 17α-methyltestoterone. Biology of reproduction. 99(2):446-460
Meier, M., Grant, J., Dowdle, A., Thomas, A., Gerton, J., Collas, P., O'Sullivan, J.M., Horsfield, J.A. (2017) Cohesin facilitates zygotic genome activation in zebrafish. Development (Cambridge, England). 145(1)
Marsman, J., Thomas, A., Osato, M., O'Sullivan, J.M., Horsfield, J.A. (2017) A DNA Contact Map for the Mouse Runx1 Gene Identifies Novel Haematopoietic Enhancers. Scientific Reports. 7:13347
Du, L.Y., Darroch, H., Keerthisinghe, P., Ashimbayeva, E., Astin, J.W., Crosier, K.E., Crosier, P.S., Warman, G., Cheeseman, J., Hall, C.J. (2017) The innate immune cell response to bacterial infection in larval zebrafish is light-regulated. Scientific Reports. 7:12657
Lee, S.L.J., Horsfield, J.A., Black, M.A., Rutherford, K., Fisher, A., Gemmell, N.J. (2017) Histological and transcriptomic effects of 17α-methyltestosterone on zebrafish gonad development. BMC Genomics. 18:557
Stayner, C., Poole, C.A., McGlashan, S.R., Pilanthananond, M., Brauning, R., Markie, D., Lett, B., Slobbe, L., Chae, A., Johnstone, A.C., Jensen, C.G., McEwan, J.C., Dittmer, K., Parker, K., Wiles, A., Blackburne, W., Leichter, A., Leask, M., Pinnapureddy, A., Jennings, M., Horsfield, J.A., Walker, R.J., Eccles, M.R. (2017) An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations. Scientific Reports. 7:1601
Hasegawa, T., Hall, C.J., Crosier, P.S., Abe, G., Kawakami, K., Kudo, A., Kawakami, A. (2017) Transient inflammatory response mediated by interleukin-1β is required for proper regeneration in zebrafish fin fold. eLIFE. 6
Dalton, J.P., Uy, B., Okuda, K.S., Hall, C.J., Denny, W.A., Crosier, P.S., Swift, S., Wiles, S. (2017) Screening of anti-mycobacterial compounds in a naturally infected zebrafish larvae model. The Journal of antimicrobial chemotherapy. 72(2):421-427
Oehlers, S.H., Flores, M.V., Hall, C.J., Wang, L., Ko, D.C., Crosier, K.E., Crosier, P.S. (2017) A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation. The FEBS journal. 284(3):402-413
Astin, J.W., Keerthisinghe, P., Du, L., Sanderson, L.E., Crosier, K.E., Crosier, P.S., Hall, C.J. (2017) Innate immune cells and bacterial infection in zebrafish. Methods in cell biology. 138:31-60
Newman, T., Jhinku, N., Meier, M., Horsfield, J. (2016) Dietary Intake Influences Adult Fertility and Offspring Fitness in Zebrafish. PLoS One. 11:e0166394
Fehr, A.G., Ruetten, M., Seth-Smith, H.M., Nufer, L., Voegtlin, A., Lehner, A., Greub, G., Crosier, P.S., Neuhauss, S.C., Vaughan, L. (2016) A Zebrafish Model for Chlamydia Infection with the Obligate Intracellular Pathogen Waddlia chondrophila.. Frontiers in microbiology. 7:1829
Gu, J., Crosier, P.S., Hall, C.J., Chen, L., Xu, X. (2016) Inflammatory pathway network-based drug repositioning and molecular phenomics. Molecular Biosystems. 12:2777-84
Castranova, D., Davis, A.E., Lo, B.D., Miller, M.F., Paukstelis, P.J., Swift, M.R., Pham, V.N., Torres-Vázquez, J., Bell, K., Shaw, K.M., Kamei, M., Weinstein, B.M. (2016) Aminoacyl-Transfer RNA Synthetase Deficiency Promotes Angiogenesis via the Unfolded Protein Response Pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 36(4):655-62
Oliver, V.F., van Bysterveldt, K.A., Cadzow, M., Steger, B., Romano, V., Markie, D., Hewitt, A.W., Mackey, D.A., Willoughby, C.E., Sherwin, T., Crosier, P.S., McGhee, C.N., Vincent, A.L. (2016) A COL17A1 Splice-Altering Mutation Is Prevalent in Inherited Recurrent Corneal Erosions. Ophthalmology. 123(4):709-22
Macdonald, N.P., Zhu, F., Hall, C.J., Reboud, J., Crosier, P.S., Patton, E.E., Wlodkowic, D., Cooper, J.M. (2016) Assessment of biocompatibility of 3D printed photopolymers using zebrafish embryo toxicity assays. Lab on a Chip. 16(2):291-7
Astin, J.W., Crosier, P.S. (2016) Lymphatics, Cancer and Zebrafish. Advances in experimental medicine and biology. 916:199-218
Hall, C., Crosier, P., Crosier, K. (2016) Inflammatory cytokines provide both infection-responsive and developmental signals for blood development: Lessons from the zebrafish. Molecular immunology. 69:113-22
Jung, H.M., Isogai, S., Kamei, M., Castranova, D., Gore, A.V., Weinstein, B.M. (2016) Imaging blood vessels and lymphatic vessels in the zebrafish. Methods in cell biology. 133:69-103
Ulrich, F., Carretero-Ortega, J., Menéndez, J., Narvaez, C., Sun, B., Lancaster, E., Pershad, V., Trzaska, S., Véliz, E., Kamei, M., Prendergast, A., Kidd, K.R., Shaw, K.M., Castranova, D.A., Pham, V.N., Lo, B.D., Martin, B.L., Raible, D.W., Weinstein, B.M., Torres-Vazquez, J. (2016) Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development (Cambridge, England). 143(1):147-59
Schuster, K., Leeke, B., Meier, M., Wang, Y., Newman, T., Burgess, S., Horsfield, J.A. (2015) A neural crest origin for cohesinopathy heart defects. Human molecular genetics. 24(24):7005-16
Sanderson, L.E., Chien, A.T., Astin, J.W., Crosier, K.E., Crosier, P.S., Hall, C.J. (2015) An inducible transgene reports activation of macrophages in live zebrafish larvae. Developmental and comparative immunology. 53(1):63-9
Okuda, K.S., Misa, J.P., Oehlers, S.H., Hall, C.J., Ellett, F., Alasmari, S., Lieschke, G.J., Crosier, K.E., Crosier, P.S., Astin, J.W. (2015) A zebrafish model of inflammatory lymphangiogenesis. Biology Open. 4(10):1270-80
Chew, T.S., O'Shea, N.R., Sewell, G.W., Oehlers, S.H., Mulvey, C.M., Crosier, P.S., Godovac-Zimmermann, J., Bloom, S.L., Smith, A.M., Segal, A.W. (2015) Optineurin deficiency contributes to impaired cytokine secretion and neutrophil recruitment in bacteria driven colitis. Disease models & mechanisms. 8(8):817-29
Koltowska, K., Paterson, S., Bower, N.I., Baillie, G.J., Lagendijk, A.K., Astin, J.W., Chen, H., Francois, M., Crosier, P.S., Taft, R.J., Simons, C., Smith, K.A., Hogan, B.M. (2015) mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish. Genes & Development. 29:1618-30
Zhu, F., Hall, C.J., Crosier, P.S., Wlodkowic, D. (2015) Interfacing Lab-on-a-Chip Embryo Technology with High-Definition Imaging Cytometry. Zebrafish. 12(4):315-8
Nicenboim, J., Malkinson, G., Lupo, T., Asaf, L., Sela, Y., Mayseless, O., Gibbs-Bar, L., Senderovich, N., Hashimshony, T., Shin, M., Jerafi-Vider, A., Avraham-Davidi, I., Krupalnik, V., Hofi, R., Almog, G., Astin, J.W., Golani, O., Ben-Dor, S., Crosier, P.S., Herzog, W., Lawson, N.D., Hanna, J.H., Yanai, I., Yaniv, K. (2015) Lymphatic vessels arise from specialized angioblasts within a venous niche. Nature. 522(7554):56-61
Akagi, J., Zhu, F., Skommer, J., Hall, C.J., Crosier, P.S., Cialkowski, M., Wlodkowic, D. (2015) Microfluidic device for a rapid immobilization of Zebrafish larvae in environmental scanning electron microscopy. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 87(3):190-4
Oehlers, S.H., Cronan, M.R., Scott, N.R., Thomas, M.I., Okuda, K.S., Walton, E.M., Beerman, R.W., Crosier, P.S., Tobin, D.M. (2015) Interception of host angiogenic signalling limits mycobacterial growth. Nature. 517(7536):612-5
Hall, C.J., Sanderson, L.E., Crosier, K.E., Crosier, P.S. (2014) Mitochondrial metabolism, reactive oxygen species, and macrophage function-fishing for insights. Journal of molecular medicine (Berlin, Germany). 92(11):1119-28
Zhu, F., Skommer, J., Huang, Y., Akagi, J., Adams, D., Levin, M., Hall, C.J., Crosier, P.S., Wlodkowic, D. (2014) Fishing on chips: Up-and-coming technological advances in analysis of zebrafish and Xenopus embryos. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 85(11):921-32
Chatterjee, A., Stockwell, P.A., Horsfield, J.A., Morison, I.M., Nakagawa, S. (2014) Base-resolution DNA methylation landscape of zebrafish brain and liver. Genomics Data. 2:342-4
Astin, J.W., Jamieson, S.M., Eng, T.C., Flores, M.V., Misa, J.P., Chien, A., Crosier, K.E., Crosier, P.S. (2014) An In Vivo Antilymphatic Screen in Zebrafish Identifies Novel Inhibitors of Mammalian Lymphangiogenesis and Lymphatic-Mediated Metastasis. Molecular cancer therapeutics. 13(10):2450-62
Hall, C.J., Wicker, S.M., Chien, A.T., Tromp, A., Lawrence, L.M., Sun, X., Krissansen, G.W., Crosier, K.E., Crosier, P.S. (2014) Repositioning drugs for inflammatory disease-fishing for new anti-inflammatory agents. Disease models & mechanisms. 7(9):1069-81
Astin, J.W., Haggerty, M.J., Okuda, K.S., Le Guen, L., Misa, J.P., Tromp, A., Hogan, B.M., Crosier, K.E., Crosier, P.S. (2014) Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting. Development (Cambridge, England). 141(13):2680-90
Akagi, J., Zhu, F., Hall, C.J., Crosier, K.E., Crosier, P.S., Wlodkowic, D. (2014) Integrated chip-based physiometer for automated fish embryo toxicity biotests in pharmaceutical screening and ecotoxicology. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 85(6):537-47
Kline, A.D., Calof, A.L., Schaaf, C.A., Krantz, I.D., Jyonouchi, S., Yokomori, K., Gauze, M., Carrico, C.S., Woodman, J., Gerton, J.L., Vega, H., Levin, A.V., Shirahige, K., Champion, M., Goodban, M.T., O'Connor, J.T., Pipan, M., Horsfield, J., Deardorff, M.A., Ishman, S.L., and Dorsett, D. (2014) Cornelia de Lange syndrome: Further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts. American journal of medical genetics. Part A. 164(6):1384-93
Hall, C.J., Boyle, R.H., Sun, X., Wicker, S.M., Misa, J.P., Krissansen, G.W., Print, C.G., Crosier, K.E., Crosier, P.S. (2014) Epidermal cells help coordinate leukocyte migration during inflammation through fatty acid-fuelled matrix metalloproteinase production. Nature communications. 5:3880
Coxam, B., Sabine, A., Bower, N.I., Smith, K.A., Pichol-Thievend, C., Skoczylas, R., Astin, J.W., Frampton, E., Jaquet, M., Crosier, P.S., Parton, R.G., Harvey, N.L., Petrova, T.V., Schulte-Merker, S., Francois, M., Hogan, B.M. (2014) Pkd1 Regulates Lymphatic Vascular Morphogenesis during Development. Cell Reports. 7:623-33
Kartopawiro, J., Bower, N.I., Karnezis, T., Kazenwadel, J., Betterman, K.L., Lesieur, E., Koltowska, K., Astin, J., Crosier, P., Vermeren, S., Achen, M.G., Stacker, S.A., Smith, K.A., Harvey, N.L., François, M., and Hogan, B.M. (2014) Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development. Human molecular genetics. 23(5):1286-97
Akagi, J., Hall, C.J., Crosier, K.E., Cooper, J.M., Crosier, P.S., and Wlodkowic, D. (2014) OpenSource lab-on-a-chip physiometer for accelerated zebrafish embryo biotests. Current Protocols Cytometry. 67:Unit 9.44
Marsman, J., O'Neill, A.C., Kao, B.R., Rhodes, J.M., Meier, M., Antony, J., Mönnich, M., and Horsfield, J.A. (2014) Cohesin and CTCF differentially regulate spatiotemporal runx1 expression during zebrafish development. Biochimica et biophysica acta. Gene regulatory mechanisms. 1839(1):50-61
Wilson, C.W., Parker, L.H., Hall, C.J., Smyczek, T., Mak, J., Crow, A., Posthuma, G., De Mazière, A., Sagolla, M., Chalouni, C., Vitorino, P., Roose-Girma, M., Warming, S., Klumperman, J., Crosier, P.S., and Ye, W. (2013) Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood. 122(22):3678-90
Wang, K.I., Salcic, Z., Yeh, J., Akagi, J., Zhu, F., Hall, C.J., Crosier, K.E., Crosier, P.S., and Wlodkowic, D. (2013) Toward embedded laboratory automation for smart lab-on-a-chip embryo arrays. Biosensors & bioelectronics. 48C:188-196
Chatterjee, A., Ozaki, Y., Stockwell, P.A., Horsfield, J.A., Morison, I.M., and Nakagawa, S. (2013) Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing. Epigenetics. 8(9):979-89
Hall, C.J., Boyle, R.H., Astin, J.W., Flores, M.V., Oehlers, S.H., Sanderson, L.E., Ellett, F., Lieschke, G.J., Crosier, K.E., and Crosier, P.S. (2013) Immunoresponsive Gene 1 Augments Bactericidal Activity of Macrophage-Lineage Cells by Regulating β-Oxidation-Dependent Mitochondrial ROS Production. Cell Metabolism. 18(2):265-278
Oehlers, S.H., Flores, M.V., Hall, C.J., Okuda, K.S., Sison, J.O., Crosier, K.E., and Crosier, P.S. (2013) Chemically Induced Intestinal Damage Models in Zebrafish Larvae. Zebrafish. 10(2):184-93
Pase, L., Layton, J.E., Wittmann, C., Ellett, F., Nowell, C.J., Reyes-Aldasoro, C.C., Varma, S., Rogers, K.L., Hall, C.J., Keightley, M.C., Crosier, P.S., Grabher, C., Heath, J.K., Renshaw, S.A., and Lieschke, G.J. (2012) Neutrophil-Delivered Myeloperoxidase Dampens the Hydrogen Peroxide Burst after Tissue Wounding in Zebrafish. Current biology : CB. 22(19):1818-1824
Yang, C.T., Cambier, C.J., Davis, J.M., Hall, C.J., Crosier, P.S., and Ramakrishnan, L. (2012) Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages. Cell Host & Microbe. 12(3):301-312
Horsfield, J.A., Print, C.G., and Mönnich, M. (2012) Diverse developmental disorders from the one ring: distinct molecular pathways underlie the cohesinopathies. Frontiers in Epigenomics. 3:171
Pan, W., Pham, V.N., Stratman, A.N., Castranova, D., Kamei, M., Kidd, K.R., Lo, B.D., Shaw, K.M., Torres-Vazquez, J., Mikelis, C.M., Gutkind, J.S., Davis, G.E., and Weinstein, B.M. (2012) CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis. Blood. 120(2):489-498
Oehlers, S.H., Flores, M.V., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2012) Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis. Disease models & mechanisms. 5(4):457-467
Okuda, K.S., Astin, J.W., Misa, J.P., Flores, M.V., Crosier, K.E., and Crosier, P.S. (2012) lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish. Development (Cambridge, England). 139(13):2381-2391
Khoshmanesh, K., Akagi, J., Hall, C.J., Crosier, K.E., Crosier, P.S., Cooper, J.M., and Wlodkowic, D. (2012) New rationale for large metazoan embryo manipulations on chip-based devices. Biomicrofluidics. 6(2):24102-2410214
Buchanan, C.M., Shih, J.H., Astin, J.W., Rewcastle, G.W., Flanagan, J.U., Crosier, P.S., and Shepherd, P.R. (2012) DMXAA (Vadimezan, ASA404) is a Multi-kinase Inhibitor Targetting VEGF-R2 in Particular. Clinical science (London, England : 1979). 122(10):449-457
Hall, C.J., Flores, M.V., Oehlers, S.H., Sanderson, L.E., Lam, E.Y., Crosier, K.E., and Crosier, P.S. (2012) Infection-Responsive Expansion of the Hematopoietic Stem and Progenitor Cell Compartment in Zebrafish Is Dependent upon Inducible Nitric Oxide. Cell Stem Cell. 10(2):198-209
Akagi, J., Khoshmanesh, K., Evans, B., Hall, C.J., Crosier, K.E., Cooper, J.M., Crosier, P.S., and Wlodkowic, D. (2012) Miniaturized Embryo Array for Automated Trapping, Immobilization and Microperfusion of Zebrafish Embryos. PLoS One. 7(5):e36630
Berman, J., Payne, E., and Hall, C. (2012) The zebrafish as a tool to study hematopoiesis, human blood diseases, and immune function. Advances in hematology. 2012:425345
Crawford, K.C., Flores, M.V., Oehlers, S.H., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2011) Zebrafish heat shock protein a4 genes in the intestinal epithelium are up-regulated during inflammation. Genesis (New York, N.Y. : 2000). 49(12):905-11
Oehlers, S.H., Flores, M.V., Hall, C.J., Swift, S., Crosier, K.E., and Crosier, P.S. (2011) The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish. Disease models & mechanisms. 4(6):832-41
Valdivia, L.E., Young, R.M., Hawkins, T.A., Stickney, H.L., Cavodeassi, F., Schwarz, Q., Pullin, L.M., Villegas, R., Moro, E., Argenton, F., Allende, M.L., and Wilson, S.W. (2011) Lef1-dependent Wnt/β-catenin signalling drives the proliferative engine that maintains tissue homeostasis during lateral line development. Development (Cambridge, England). 138(18):3931-3941
Oehlers, S.H., Flores, M.V., Chen, T., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2011) Topographical distribution of antimicrobial genes in the zebrafish intestine. Developmental and comparative immunology. 35(3):385-391
Mönnich, M., Kuriger, Z., Print, C.G., and Horsfield, J.A. (2011) A zebrafish model of Roberts syndrome reveals that Esco2 depletion interferes with development by disrupting the cell cycle. PLoS One. 6(5):e20051
Oehlers, S.H., Flores, M.V., Okuda, K.S., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2011) A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents. Developmental dynamics : an official publication of the American Association of Anatomists. 240(1):288-298
Flores, M.V., Crawford, K.C., Pullin, L.M., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2010) Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties. Biochemical and Biophysical Research Communications. 400(1):164-168
Rhodes, J.M., Bentley, F.K., Print, C.G., Dorsett, D., Misulovin, Z., Dickinson, E.J., Crosier, K.E., Crosier, P.S., and Horsfield, J.A. (2010) Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved. Developmental Biology. 344(2):637-649
Lam, E.Y., Hall, C.J., Crosier, P.S., Crosier, K.E., and Flores, M.V. (2010) Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells. Blood. 116(6):909-914
Flores, M.V., Hall, C.J., Crosier, K.E., and Crosier, P.S. (2010) Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologies. Developmental dynamics : an official publication of the American Association of Anatomists. 239(7):2128-2135
Oehlers, S.H., Flores, M.V., Hall, C.J., O'Toole, R., Swift, S., Crosier, K.E., and Crosier, P.S. (2010) Expression of zebrafish cxcl8 (interleukin-8) and its receptors during development and in response to immune stimulation. Developmental and comparative immunology. 34(3):352-359
Kamei, M., Isogai, S., Pan, W., and Weinstein, B.M. (2010) Chapter 2 - Imaging blood vessels in the zebrafish. Methods in cell biology. 100:27-54
Mönnich, M., Banks, S., Eccles, M., Dickinson, E., and Horsfield, J. (2009) Expression of cohesin and condensin genes during zebrafish development supports a non-proliferative role for cohesin. Gene expression patterns : GEP. 9(8):586-594
Brannon, M.K., Davis, J.M., Mathias, J.R., Hall, C.J., Emerson, J.C., Crosier, P.S., Huttenlocher, A., Ramakrishnan, L., and Moskowitz, S.M. (2009) Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos. Cellular Microbiology. 11(5):755-768
Hall, C., Flores, M.V., Chien, A., Davidson, A., Crosier, K., and Crosier, P. (2009) Transgenic zebrafish reporter lines reveal conserved Toll-like receptor signaling potential in embryonic myeloid leukocytes and adult immune cell lineages. Journal of Leukocyte Biology. 85(5):751-765
Stoletov, K., Fang, L., Choi, S.H., Hartvigsen, K., Hansen, L.F., Hall, C., Pattison, J., Juliano, J., Miller, E.R., Almazan, F., Crosier, P., Witztum, J.L., Klemke, R.L., and Miller, Y.I. (2009) Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish. Circulation research. 104(8):952-960
Liongue, C., Hall, C.J., O'Connell, B.A., Crosier, P., and Ward, A.C. (2009) Zebrafish granulocyte colony-stimulating factor receptor signaling promotes myelopoiesis and myeloid cell migration. Blood. 113(11):2535-2546
Lam, E.Y., Chau, J.Y., Kalev-Zylinska, M.L., Fountaine, T.M., Mead, R.S., Hall, C.J., Crosier, P.S., Crosier, K.E., and Flores, M.V. (2009) Zebrafish runx1 promoter-EGFP transgenics mark discrete sites of definitive blood progenitors. Blood. 113(6):1241-1249
Hall, C., Flores, M.V., Crosier, K., and Crosier, P. (2009) Live cell imaging of zebrafish leukocytes. Methods in molecular biology (Clifton, N.J.). 546:255-271
Lam, E.Y.N. (2009) Regulation of stem cell devleopment by runx transcription factors. Ph.D. Thesis. :239p
Storm, T. (2009) The intestinal inflammatory response to bacterial challenge with respect to the toll-like receptor signaling pathway in the zebrafish. Master's Thesis. :134p
Hall, C.J., Flores, M.V., Crosier, K.E., and Crosier, P.S. (2008) Live imaging early immune cell ontogeny and function in zebrafish Danio rerio. Journal of Fish Biology. 73(8):1833-1871
Flores, M.V., Hall, C.J., Davidson, A.J., Singh, P.P., Mahagaonkar, A.A., Zon, L.I., Crosier, K.E., and Crosier, P.S. (2008) Intestinal Differentiation in Zebrafish Requires Cdx1b, a Functional Equivalent of Mammalian Cdx2. Gastroenterology. 135(5):1665-1675
Cvejic, A., Hall, C., Bak-Maier, M., Flores, M.V., Crosier, P., Redd, M.J., and Martin, P. (2008) Analysis of WASp function during the wound inflammatory response - live-imaging studies in zebrafish larvae. Journal of Cell Science. 121(Pt 19):3196-3206
Flores, M.V., Lam, E.Y., Crosier, K.E., and Crosier, P.S. (2008) Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish. Nature cell biology. 10(3):346-352
Aleström, P., Begemann, G., Carvan, M.J. 3rd, Cheng, K.C., Crosier, K., Crosier, P., Ekker, S., Huttenlocher, A., Kawakami, K., Kelly, G., Korzh, V., Lieschke, G., Mione, M., Neely, M.N., Neuhauss, S., and Trede, N.S. (2008) Views on four key questions about zebrafish research. Zebrafish. 5(1):9-24
Buchner, D.A., Su, F., Yamaoka, J.S., Kamei, M., Shavit, J.A., Barthel, L.K., McGee, B., Amigo, J.D., Kim, S., Hanosh, A.W., Jagadeeswaran, P., Goldman, D., Lawson, N.D., Raymond, P.A., Weinstein, B.M., Ginsburg, D., and Lyons, S.E. (2007) pak2a mutations cause cerebral hemorrhage in redhead zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 104(35):13996-140001
Horsfield, J.A., Anagnostou, S.H., Hu, J.K., Cho, K.H., Geisler, R., Lieschke, G., Crosier, K.E., and Crosier, P.S. (2007) Cohesin-dependent regulation of Runx genes. Development (Cambridge, England). 134(14):2639-2649
Hall, C., Flores, M.V., Storm, T., Crosier, K., and Crosier, P. (2007) The zebrafish lysozyme C promoter drives myeloid-specific expression in transgenic fish. BMC Developmental Biology. 7(1):42
Flores, M.V., Hall, C., Jury, A., Crosier, K., and Crosier, P. (2007) The zebrafish retinoid-related orphan receptor (ror) gene family. Gene expression patterns : GEP. 7(5):535-543
Crawford, K.C. (2007) Characterisation of duox and hsp110/sse genes in the zebrafish gut mucosa. Master's Thesis. :137p
Hall, C., Flores, M.V., Murison, G., Crosier, K., and Crosier, P. (2006) An essential role for zebrafish Fgfrl1 during gill cartilage development. Mechanisms of Development. 123(12):925-940
Flores, M.V., Lam, E.Y., Crosier, P., and Crosier, K. (2006) A hierarchy of Runx transcription factors modulate the onset of chondrogenesis in craniofacial endochondral bones in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 235(11):3166-3176
Kamei, M., Brian Saunders, W., Bayless, K.J., Dye, L., Davis, G.E., and Weinstein, B.M. (2006) Endothelial tubes assemble from intracellular vacuoles in vivo. Nature. 442(7101):453-456
Shaw, K.M., Castranova, D.A., Pham, V.N., Kamei, M., Kidd, K.R., Lo, B.D., Torres-Vazquez, J., Ruby, A., and Weinstein, B.M. (2006) fused-somites-like mutants exhibit defects in trunk vessel patterning. Developmental dynamics : an official publication of the American Association of Anatomists. 235(7):1753-1760
Pollard, S.M., Parsons, M.J., Kamei, M., Kettleborough, R.N., Thomas, K.A., Pham, V.N., Bae, M.K., Scott, A., Weinstein, B.M., and Stemple, D.L. (2006) Essential and overlapping roles for laminin alpha chains in notochord and blood vessel formation. Developmental Biology. 289(1):64-76
Kamei, M., and Weinstein, B.M. (2005) Long-Term Time-Lapse Fluorescence Imaging of Developing Zebrafish. Zebrafish. 2(2):113-123
Flores, M.V., Tsang, V.W., Hu, W., Kalev-Zylinska, M., Postlethwait, J., Crosier, P., Crosier, K., and Fisher, S. (2004) Duplicate zebrafish runx2 orthologues are expressed in developing skeletal elements. Gene expression patterns : GEP. 4(5):573-581
Cattin, P., and Crosier, P. (2004) A nursery that improves zebrafish fry survival. The Zebrafish: Genetics, Genomics and Informatics, 2nd ed., Methods Cell Biol.. 77:593-598
Kamei, M., Isogai, S., and Weinstein, B.M. (2004) Imaging blood vessels in the zebrafish. The Zebrafish: Cellular and Developmental Biology,2nd Ed. Methods Cell Biol.. 76:51-74
Kamei, M., Kidd, K.R., Torres-Vazquez, J., and Weinstein, B.M. (2004) Making waves in Madison: the 6th International Meeting on Zebrafish Development and Genetics. Zebrafish. 1(2):145-163
Kalev-Zylinska, M.L., Horsfield, J.A., Flores, M.V., Postlethwait, J.H., Chau, J.Y., Cattin, P.M., Vitas, M.R., Crosier, P.S., and Crosier, K.E. (2003) Runx3 is required for hematopoietic development in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 228(3):323-336
Torres-Vazquez, J., Kamei, M., and Weinstein, B.M. (2003) Molecular distinction between arteries and veins. Cell and tissue research. 314(1):43-59
Hall, C.J., Flores, M.V.C., Davidson, A.J., Crosier, K.E., and Crosier, P.S. (2002) Radar is required for the establishment of vascular integrity in the zebrafish. Developmental Biology. 251(1):105-117
Horsfield, J., Ramachandran, A., Reuter, K., LaVallie, E., Collins-Racie, L., Crosier, K., and Crosier, P. (2002) Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development. Mechanisms of Development. 115(1-2):15-26
Kalev-Zylinska, M.L., Horsfield, J.A., Flores, M.V.C., Postlethwait, J.H., Vitas, M.R., Baas, A.M., Crosier, P.S., and Crosier, K.E. (2002) Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis. Development (Cambridge, England). 129(8):2015-2030
Crosier, P.S., Kalev-Zylinska, M.L., Hall, C.J., Flores, M.V.C., Horsfield, J.A., and Crosier, K.E. (2002) Pathways in blood and vessel development revealed through zebrafish genetics. The International journal of developmental biology. 46(4):493-502
Hall, C.J. (2002) Radar/Gdf6a function during zebrafish (Danio rerio) embryogenesis. Ph.D. Thesis. :251p
Crosier, P.S., Bardsley, A., Horsfield, J.A., Krassowska, A.K., Lavallie, E.R., Collins-Racie, L.A., Postlethwait, J.H., Yan, Y.-L., McCoy, J.M., and Crosier, K.E. (2001) In situ hybridization screen in zebrafish for the selection of genes encoding secreted proteins. Developmental dynamics : an official publication of the American Association of Anatomists. 222(4):637-644
Kalev, M.L., Horsfield, J.A., Flores, M.C., Postlethwait, J.H., Vitas, M.R., Baas, A.M., Crosier, P.S., and Crosier, K.E. (2001) Runt family transcription factors are required for zebrafish hematopoiesis, and their function is disrupted by a human RUNX1-CBF2T1 transgene. Blood. 98(11):1892
Davidson, A.J., Postlethwait, J.H., Yan, Y.-L., Beier, D.R., Van Doren, C., Förnzler, D., Celeste, A.J., Crosier, K.E., and Crosier, P.S. (1999) Isolation of zebrafish gdf7 and comparative genetic mapping of genes belonging to the growth/differentiation factor 5, 6, 7 subgroup of the TGF-beta superfamily. Genome research. 9:121-129