The Weinstein laboratory is one of the leading research groups studying vascular development in the zebrafish.

Weinstein lab members developed many of the most commonly used tools and methods for studying vessels in the fish, including a confocal microangiography method, an atlas of the anatomy of the developing zebrafish vasculature, numerous vascular-specific transgenic lines, and methods for high resolution in vivo imaging of zebrafish blood vessels.

The laboratory has also made many important discoveries in the areas of vascular specification, differentiation, and patterning, including a novel pathway specifying arterial identity, a role for neuronal guidance factors in vascular patterning, a mechanism for vascular tube formation in vivo, and identification and characterization of a lymphatic vascular system in the zebrafish.