ZFIN ID: ZDB-LAB-970409-25
Yamasu Lab
PI/Director: Yamasu, Kyo
Contact Person: Yamasu, Kyo
Email: kyamasu@mail.saitama-u.ac.jp
URL: http://devbiol.seitai.saitama-u.ac.jp/
Address: Division of Life Science Graduate School of Science and Engineering Saitama University Shimo-Okubo 255, Sakura-ku Saitama 338-8570 JAPAN
Country: Japan
Phone: 81-48-858-3417
Fax: 81-48-858-3698
Line Designation: sud


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 13 genomic features


STATEMENT OF RESEARCH INTERESTS
1. Transcriptional regulation in zebrafish embryo, with special reference to the positional information along body axes.

2. Molecular mechanism underlying the regionalization of the brain primordium during development.


LAB MEMBERS
Nakayama, Yukiko Graduate Student Ota, Satoshi Graduate Student


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Zaman, T., Fahad, T.M., Rana, M., Hossain, M.S., Mamun, A., Haque, M.A., Sarker, A., Islam, M.S., Haque, M.M.L., Naz, T., Manik, M.I.N., Ali, H., Yamasu, K., Khan, A. (2023) Endosulfan affects embryonic development synergistically under elevated ambient temperature. Environmental science and pollution research international. 30(29):73393-73404
Yuikawa, T., Ikeda, M., Tsuda, S., Saito, S., Yamasu, K. (2021) Involvement of Oct4-type transcription factor Pou5f3 in posterior spinal cord formation in zebrafish embryos. Development, growth & differentiation. 63(6):306-322
Takahashi, K., Ito, Y., Yoshimura, M., Nikaido, M., Yuikawa, T., Kawamura, A., Tsuda, S., Kage, D., Yamasu, K. (2020) A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish. Developmental Biology. 472:1-17
Akama, K., Ebata, K., Maeno, A., Taminato, T., Otosaka, S., Gengyo-Ando, K., Nakai, J., Yamasu, K., Kawamura, A. (2019) Role of somite patterning in the formation of Weberian apparatus and pleural rib in zebrafish. Journal of anatomy. 236(4):622-629
Inomata, C., Yuikawa, T., Nakayama-Sadakiyo, Y., Kobayashi, K., Ikeda, M., Chiba, M., Konishi, C., Ishioka, A., Tsuda, S., Yamasu, K. (2019) Involvement of an Oct4-related PouV gene, pou5f3/pou2, in neurogenesis in the early neural plate of zebrafish embryos. Developmental Biology. 457(1):30-42
Ban, H., Yokota, D., Otosaka, S., Kikuchi, M., Kinoshita, H., Fujino, Y., Yabe, T., Ovara, H., Izuka, A., Akama, K., Yamasu, K., Takada, S., Kawamura, A. (2019) Transcriptional autoregulation of zebrafish tbx6 is required for somite segmentation. Development (Cambridge, England). 146(18):
Fujino, Y., Yamada, K., Sugaya, C., Ooka, Y., Ovara, H., Ban, H., Akama, K., Otosaka, S., Kinoshita, H., Yamasu, K., Mishima, Y., Kawamura, A. (2018) Deadenylation by the CCR4-NOT complex contributes to the turnover of hairy-related mRNAs in the zebrafish segmentation clock. FEBS letters. 592(20):3388-3398
Tsuda, S., Hiyoshi, K., Miyazawa, H., Kinno, R., Yamasu, K. (2018) 4D imaging identifies dynamic migration and the fate of gbx2-expressing cells in the brain primordium of zebrafish. Neuroscience letters. 690:112-119
Okumura, K., Kakinuma, H., Amo, R., Okamoto, H., Yamasu, K., Tsuda, S. (2018) Optical measurement of neuronal activity in the developing cerebellum of zebrafish using voltage-sensitive dye imaging. Neuroreport. 29(16):1349-1354
Kinoshita, H., Ohgane, N., Fujino, Y., Yabe, T., Ovara, H., Yokota, D., Izuka, A., Kage, D., Yamasu, K., Takada, S., Kawamura, A. (2018) Functional roles of the Ripply-mediated suppression of segmentation gene expression at the anterior presomitic mesoderm in zebrafish. Mechanisms of Development. 152:21-31
Miyazawa, H., Okumura, K., Hiyoshi, K., Maruyama, K., Kakinuma, H., Amo, R., Okamoto, H., Yamasu, K., Tsuda, S. (2018) Optical interrogation of neuronal circuitry in zebrafish using genetically encoded voltage indicators. Scientific Reports. 8:6048
Nikaido, M., Izumi, S., Ohnuki, H., Takigawa, Y., Yamasu, K., Hatta, K. (2018) Early development of the enteric nervous system visualized by using a new transgenic zebrafish line harboring a regulatory region for choline acetyltransferase a (chata) gene. Gene expression patterns : GEP. 28:12-21
Kobayashi, K., Khan, A., Ikeda, M., Nakamoto, A., Maekawa, M., Yamasu, K. (2018) In vitro analysis of the transcriptional regulatory mechanism of zebrafish pou5f3. Experimental cell research. 364(1):28-41
Wang, Z., Nakayama, Y., Tsuda, S., Yamasu, K. (2018) The role of gastrulation brain homeobox 2 (gbx2) in the development of the ventral telencephalon in zebrafish embryos. Differentiation; research in biological diversity. 99:28-40
Nakayama, Y., Inomata, C., Yuikawa, T., Tsuda, S., Yamasu, K. (2017) Comprehensive analysis of target genes in zebrafish embryos reveals gbx2 involvement in neurogenesis. Developmental Biology. 430(1):237-248
Ota, S., Taimatsu, K., Yanagi, K., Namiki, T., Ohga, R., Higashijima, S.I., Kawahara, A. (2016) Functional visualization and disruption of targeted genes using CRISPR/Cas9-mediated eGFP reporter integration in zebrafish. Scientific Reports. 6:34991
Taminato, T., Yokota, D., Araki, S., Ovara, H., Yamasu, K., Kawamura, A. (2016) Enhancer activity-based identification of functional enhancers using zebrafish embryos. Genomics. 108(2):102-7
Kawahara, A., Hisano, Y., Ota, S., Taimatsu, K. (2016) Site-Specific Integration of Exogenous Genes Using Genome Editing Technologies in Zebrafish. International Journal of Molecular Sciences. 17(5)
Kawamura, A., Ovara, H., Ooka, Y., Kinoshita, H., Hoshikawa, M., Nakajo, K., Yokota, D., Fujino, Y., Higashijima, S.I., Takada, S., Yamasu, K. (2016) Posterior-anterior gradient of zebrafish hes6 expression in the presomitic mesoderm is established by the combinatorial functions of the downstream enhancer and 3'UTR. Developmental Biology. 409(2):543-54
Ota, S., Kawahara, A. (2016) Detection of Multiple Genome Modifications Induced by the CRISPR/Cas9 System. Methods in molecular biology (Clifton, N.J.). 1451:53-63
Hisano, Y., Inoue, A., Taimatsu, K., Ota, S., Ohga, R., Kotani, H., Muraki, M., Aoki, J., Kawahara, A. (2015) Comprehensive analysis of sphingosine-1-phosphate receptor mutants during zebrafish embryogenesis. Genes to cells : devoted to molecular & cellular mechanisms. 20(8):647-58
Kotani, H., Taimatsu, K., Ohga, R., Ota, S., Kawahara, A. (2015) Efficient Multiple Genome Modifications Induced by the crRNAs, tracrRNA and Cas9 Protein Complex in Zebrafish. PLoS One. 10:e0128319
Hisano, Y., Sakuma, T., Nakade, S., Ohga, R., Ota, S., Okamoto, H., Yamamoto, T., Kawahara, A. (2015) Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish. Scientific Reports. 5:8841
Ota, S., Hisano, Y., Ikawa, Y., Kawahara, A. (2014) Multiple genome modifications by the CRISPR/Cas9 system in zebrafish. Genes to cells : devoted to molecular & cellular mechanisms. 19(7):555-64
Ota, S., and Kawahara, A. (2014) Zebrafish: a model vertebrate suitable for the analysis of human genetic disorders. Congenital anomalies. 54(1):8-11
Hisano, Y., Ota, S., and Kawahara, A. (2014) Genome editing using artificial site-specific nucleases in zebrafish. Development, growth & differentiation. 56(1):26-33
Nakayama, Y., Kikuta, H., Kanai, M., Yoshikawa, K., Kawamura, A., Kobayashi, K., Wang, Z., Khan, A., Kawakami, K., and Yamasu, K. (2013) Gbx2 functions as a transcriptional repressor to regulate the specification and morphogenesis of the mid-hindbrain junction in a dosage- and stage-dependent manner. Mechanisms of Development. 130(11-12):532-52
Hisano, Y., Ota, S., Takada, S., and Kawahara, A. (2013) Functional cooperation of spns2 and fibronectin in cardiac and lower jaw development. Biology Open. 2(8):789-794
Ota, S., Hisano, Y., Muraki, M., Hoshijima, K., Dahlem, T.J., Grunwald, D.J., Okada, Y., and Kawahara, A. (2013) Efficient identification of TALEN-mediated genome modifications using heteroduplex mobility assays. Genes to cells : devoted to molecular & cellular mechanisms. 18(6):450-458
Hisano, Y., Ota, S., Arakawa, K., Muraki, M., Kono, N., Oshita, K., Sakuma, T., Tomita, M., Yamamoto, T., Okada, Y., and Kawahara, A. (2013) Quantitative assay for TALEN activity at endogenous genomic loci. Biology Open. 2(4):363-367
Khan, A., Nakamoto, A., Okamoto, S., Tai, M., Nakayama, Y., Kobayashi, K., Kawamura, A., Takeda, H., and Yamasu, K. (2012) Pou2, a class V POU-type transcription factor in zebrafish, regulates dorsoventral patterning and convergent extension movement at different blastula stages. Mechanisms of Development. 129(9-12):219-235
Khan, A., Nakamoto, A., Tai, M., Saito, S., Nakayama, Y., Kawamura, A., Takeda, H., and Yamasu, K. (2012) Mesendoderm specification depends on the function of Pou2, the class V POU-type transcription factor, during zebrafish embryogenesis. Development, growth & differentiation. 54(7):686-701
Ota, S., Ishitani, S., Shimizu, N., Matsumoto, K., Itoh, M., and Ishitani, T. (2012) NLK positively regulates Wnt/beta-catenin signalling by phosphorylating LEF1 in neural progenitor cells. The EMBO journal. 31(8):1904-1915
Ishioka, A., Jindo, T., Kawanabe, T., Hatta, K., Parvin, M.S., Nikaido, M., Kuroyanagi, Y., Takeda, H., and Yamasu, K. (2011) Retinoic acid-dependent establishment of positional information in the hindbrain was conserved during vertebrate evolution. Developmental Biology. 350(1):154-168
Ota, S., Tonou-Fujimori, N., Nakayama, Y., Ito, Y., Kawamura, A., and Yamasu, K. (2010) FGF receptor gene expression and its regulation by FGF signaling during early zebrafish development. Genesis (New York, N.Y. : 2000). 48(12):707-716
Ota, S., Tonou-Fujimori, N., and Yamasu, K. (2009) The roles of the FGF signal in zebrafish embryos analyzed using constitutive activation and dominant-negative suppression of different FGF receptors. Mechanisms of Development. 126(1-2):1-17
Parvin, M.S., Okuyama, N., Inoue, F., Islam, M.E., Kawakami, A., Takeda, H., and Yamasu, K. (2008) Autoregulatory loop and retinoic acid repression regulate pou2/pou5f1 gene expression in the zebrafish embryonic brain. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(5):1373-1388
Inoue, F., Parvin, M.S., and Yamasu, K. (2008) Transcription of fgf8 is regulated by activating and repressive cis-elements at the midbrain-hindbrain boundary in zebrafish embryos. Developmental Biology. 316(2):471-486
Nikaido, M., Doi, K., Shimizu, T., Hibi, M., Kikuchi, Y., and Yamasu, K. (2007) Initial specification of the epibranchial placode in zebrafish embryos depends on the fibroblast growth factor signal. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(2):564-571
Islam, M.E., Kikuta, H., Inoue, F., Kanai, M., Kawakami, A., Parvin, M.S., Takeda, H., and Yamasu, K. (2006) Three enhancer regions regulate gbx2 gene expression in the isthmic region during zebrafish development. Mechanisms of Development. 123(12):907-924
Inoue, F., Nagayoshi, S., Ota, S., Islam, M.E., Tonou-Fujimori, N., Odaira, Y., Kawakami, K., and Yamasu, K. (2006) Genomic organization, alternative splicing, and multiple regulatory regions of the zebrafish fgf8 gene. Development, growth & differentiation. 48(7):447-462
Kikuta, H., Kanai, M., Ito, Y., and Yamasu, K. (2003) gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain. Developmental Dynamics : an official publication of the American Association of Anatomists. 228(3):433-450
Hirate, Y., Okamoto, H. and Yamasu, K. (2003) Structure of the zebrafish fasciclin I-related extracellular matrix protein (betaig-h3) and its characteristic expression during embryogenesis. Gene expression patterns : GEP. 3(3):331-336
Tonou-Fujimori, N., Takahashi, M., Onodera, H., Kikuta, H., Koshida, S., Takeda, H., and Yamasu, K. (2002) RETRACTED: Expression of the FGF receptor 2 gene (fgfr2) during embryogenesis in the zebrafish Danio rerio. Gene expression patterns : GEP. 2(3-4):183-188
Tonou-Fujimori, N., Takahashi, M., Onodera, H., Kikuta, H., Koshida, S., Takeda, H., and Yamasu, K. (2002) Expression of the FGF receptor 2 gene (fgfr2) during embryogenesis in the zebrafish Danio rerio. Mechanisms of Development. (Suppl.) 119:S173-S178
Hirate, Y., Mieda, M., Harada, T., Yamasu, K., and Okamoto, H. (2001) Identification of ephrin-A3 and novel genes specific to the midbrain-MHB in embryonic zebrafish by ordered differential display. Mechanisms of Development. 107(1-2):83-96
Sawada, A., Fritz, A., Jiang, Y., Yamamoto, A., Yamasu, K., Kuroiwa, A., Saga, Y., and Takeda, H. (2000) Zebrafish Mesp family genes, mesp-a and mesp-b are segmentally expressed in the presomitic mesoderm, and Mesp-b confers the anterior identity to the developing somites. Development (Cambridge, England). 127(8):1691-1702