ZFIN Lab: Evason Lab

ZFIN ID: ZDB-LAB-240423-1

Evason Lab

PI/Director:	Evason, Kimberley
Contact Person:	Evason, Kimberley
Email:	kimevason@gmail.com
URL:	https://uofuhealth.utah.edu/huntsman/labs/evason
Address:	The University of Utah 2000 Circle of Hope HCI 3161 Salt Lake City, UT 84112
Country:	United States
Phone:	801-587-4606
Fax:
Line Designation:	z

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

The Evason lab is focused on liver cancer and liver development.

LAB MEMBERS

Castro, Jessye Graduate Student	Miscik, Natalie Graduate Student	Saxena, Aavrati Graduate Student
VanSant-Webb, Chad Graduate Student	Kalasekar, Sharanya Research Staff	Smith, Richard Research Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Bowman, K.E.R., Ahne, L., O'Brien, L., Vander Mause, E.R., Lu, P., Wallis, B., Evason, K.J., Lim, C.S. (2022) p53-Bad* Fusion Gene Therapy Induces Apoptosis In Vitro and Reduces Zebrafish Tumor Burden in Hepatocellular Carcinoma. Molecular pharmaceutics. 20(1):331-340

Ellis, J.L., Evason, K.J., Zhang, C., Fourman, M.N., Liu, J., Ninov, N., Delous, M., Vanhollebeke, B., Fiddes, I., Otis, J.P., Houvras, Y., Farber, S.A., Xu, X., Lin, X., Stainier, D.Y.R., Yin, C. (2022) A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish. Hepatology communications. 6(11):3083-3097

Kotiyal, S., Fulbright, A., O'Brien, L.K., Evason, K.J. (2020) Quantifying Liver Size in Larval Zebrafish Using Brightfield Microscopy. Journal of visualized experiments : JoVE. (156):

Chaturantabut, S., Shwartz, A., Evason, K.J., Cox, A.G., Labella, K., Schepers, A.G., Yang, S., Aravena, M., Houvras, Y., Mancio-Silva, L., Romano, S., Gorelick, D.A., Cohen, D.E., Zon, L.I., Bhatia, S.N., North, T.E., Goessling, W. (2019) Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. 156(6):1788-1804.e13

So, J., Khaliq, M., Evason, K., Ninov, N., Martin, B.L., Stainier, D.Y.R., Shin, D. (2017) Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity. Hepatology (Baltimore, Md.). 67(6):2352-2366

Cox, A.G., Tsomides, A., Kim, A.J., Saunders, D., Hwang, K.L., Evason, K.J., Heidel, J., Brown, K.K., Yuan, M., Lien, E.C., Lee, B.C., Nissim, S., Dickinson, B., Chhangawala, S., Chang, C.J., Asara, J.M., Houvras, Y., Gladyshev, V.N., Goessling, W. (2016) Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 113(38):E5562-71

Cox, A.G., Hwang, K.L., Brown, K.K., Evason, K.J., Beltz, S., Tsomides, A., O'Connor, K., Galli, G.G., Yimlamai, D., Chhangawala, S., Yuan, M., Lien, E.C., Wucherpfennig, J., Nissim, S., Minami, A., Cohen, D.E., Camargo, F.D., Asara, J.M., Houvras, Y., Stainier, D.Y., Goessling, W. (2016) Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature cell biology. 18(8):886-96

Evason, K.J., Francisco, M.T., Juric, V., Balakrishnan, S., Lopez Pazmino, M.D., Gordan, J.D., Kakar, S., Spitsbergen, J., Goga, A., Stainier, D.Y. (2015) Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish. PLoS Genetics. 11:e1005305

Ghajar, C.M., Peinado, H., Mori, H., Matei, I.R., Evason, K.J., Brazier, H., Almeida, D., Koller, A., Hajjar, K.A., Stainier, D.Y., Chen, E.I., Lyden, D., and Bissell, M.J. (2013) The perivascular niche regulates breast tumour dormancy. Nature cell biology. 15(7):807-817

Yin, C., Evason, K.J., Maher, J.J., and Stainier, D.Y. (2012) The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: Analysis of stellate cell entry into the developing liver. Hepatology (Baltimore, Md.). 56(5):1958-1970

Cheung, I.D., Bagnat, M., Ma, T.P., Datta, A., Evason, K., Moore, J.C., Lawson, N.D., Mostov, K.E., Moens, C.B., and Stainier, D.Y. (2012) Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. Developmental Biology. 361(1):68-78