ZFIN ID: ZDB-LAB-231214-4
Zebrafish Core Facility, University of Bonn
PI/Director: Odermatt, Benjamin
Co-PI / Senior
Researcher:		 Schöpper, Hanna
Contact Person: Odermatt, Benjamin
Email: b.odermatt@uni-bonn.de
URL: https://btc.uni-bonn.de/zebrafish/
Address: Anatomy Building Nussallee 10 53115 Bonn
Country: Germany
Phone: 0049-228-73-9021
Fax:
Line Designation: bn


GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available


STATEMENT OF RESEARCH INTERESTS
As a core facility we offer different services for our users:

Import and rising of new zebrafish lines

Keeping and mating of zebrafish lines on behalf of our users

Injection of zebrafish eggs or embryos

Transplantation of cells into two or three days old zebrafish larvae

Generating of new zebrafish lines

Support on imaging on our fluoreszenz, confocal or two photon microscopes

Direct transfer of fish samples to electron microscopy (in house)


LAB MEMBERS
Lindenberg, Tobias Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Stegmann, J.D., Kalanithy, J.C., Dworschak, G.C., Ishorst, N., Mingardo, E., Lopes, F.M., Ho, Y.M., Grote, P., Lindenberg, T.T., Yilmaz, Ö., Channab, K., Seltzsam, S., Shril, S., Hildebrandt, F., Boschann, F., Heinen, A., Jolly, A., Myers, K., McBride, K., Bekheirnia, M.R., Bekheirnia, N., Scala, M., Morleo, M., Nigro, V., Torella, A., TUDP consortium, Pinelli, M., Capra, V., Accogli, A., Maitz, S., Spano, A., Olson, R.J., Klee, E.W., Lanpher, B.C., Jang, S.S., Chae, J.H., Steinbauer, P., Rieder, D., Janecke, A.R., Vodopiutz, J., Vogel, I., Blechingberg, J., Cohen, J.L., Riley, K., Klee, V., Walsh, L.E., Begemann, M., Elbracht, M., Eggermann, T., Stoppe, A., Stuurman, K., van Slegtenhorst, M., Barakat, T.S., Mulhern, M.S., Sands, T.T., Cytrynbaum, C., Weksberg, R., Isidori, F., Pippucci, T., Severi, G., Montanari, F., Kruer, M.C., Bakhtiari, S., Darvish, H., Reutter, H., Hagelueken, G., Geyer, M., Woolf, A.S., Posey, J.E., Lupski, J.R., Odermatt, B., Hilger, A.C. (2024) Bi-allelic variants in CELSR3 are implicated in central nervous system and urinary tract anomalies. NPJ genomic medicine. 9:1818
Reinhardt, F., Coen, L., Rivandi, M., Franken, A., Setyono, E.S.A., Lindenberg, T., Eberhardt, J., Fehm, T., Niederacher, D., Knopf, F., Neubauer, H. (2023) DanioCTC: Analysis of Circulating Tumor Cells from Metastatic Breast Cancer Patients in Zebrafish Xenografts. Cancers. 15(22):
Kolvenbach, C.M., Dworschak, G.C., Rieke, J.M., Woolf, A.S., Reutter, H., Odermatt, B., Hilger, A.C. (2023) Modelling human lower urinary tract malformations in zebrafish. Molecular and cellular pediatrics. 10:22
Enders, M., Weier, A., Chunder, R., An, Y., Bremm, F., Feigenspan, A., Buettner, C., Ekici, A.B., Mingardo, E., Odermatt, B., Kuerten, S. (2023) Impact of the Voltage-Gated Calcium Channel Antagonist Nimodipine on the Development of Oligodendrocyte Precursor Cells. International Journal of Molecular Sciences. 24(4):
Kolvenbach, C.M., Felger, T., Schierbaum, L., Thiffault, I., Pastinen, T., Szczepańska, M., Zaniew, M., Adamczyk, P., Bayat, A., Yilmaz, Ö., Lindenberg, T.T., Thiele, H., Hildebrandt, F., Hinderhofer, K., Moog, U., Hilger, A.C., Sullivan, B., Bartik, L., Gnyś, P., Grote, P., Odermatt, B., Reutter, H.M., Dworschak, G.C. (2022) X-linked variations in SHROOM4 are implicated in congenital anomalies of the urinary tract and the anorectal, cardiovascular and central nervous systems. Journal of Medical Genetics. 60(6):587-596
Häberlein, F., Mingardo, E., Merten, N., Schulze Köhling, N.K., Reinoß, P., Simon, K., Japp, A., Nagarajan, B., Schrage, R., Pegurier, C., Gillard, M., Monk, K.R., Odermatt, B., Kostenis, E., Gomeza, J. (2022) Humanized zebrafish as a tractable tool for in vivo evaluation of pro-myelinating drugs. Cell chemical biology. 29(10):1541-1555.e7
Harder, A., Nagarajan, B., Odermatt, B., Kubitscheck, U. (2022) Automatic detector synchronization for long-term imaging using confocal light-sheet microscopy. Microscopy research and technique. 86(2):125-136
Wilms, C., Lepka, K., Häberlein, F., Edwards, S., Felsberg, J., Pudelko, L., Lindenberg, T.T., Poschmann, G., Qin, N., Volbracht, K., Prozorovski, T., Meuth, S.G., Kahlert, U.D., Remke, M., Aktas, O., Reifenberger, G., Bräutigam, L., Odermatt, B., Berndt, C. (2021) Glutaredoxin 2 promotes SP-1-dependent CSPG4 transcription and migration of wound healing NG2 glia and glioma cells: Enzymatic Taoism. Redox Biology. 49:102221
Turan, F., Yilmaz, Ö., Schünemann, L., Lindenberg, T.T., Kalanithy, J.C., Harder, A., Ahmadi, S., Duman, T., MacDonald, R.B., Winter, D., Liu, C., Odermatt, B. (2021) Effect of modulating glutamate signaling on myelinating oligodendrocytes and their development-A study in the zebrafish model. Journal of neuroscience research. 99(11):2774-2792
Dworschak, G.C., Punetha, J., Kalanithy, J.C., Mingardo, E., Erdem, H.B., Akdemir, Z.C., Karaca, E., Mitani, T., Marafi, D., Fatih, J.M., Jhangiani, S.N., Hunter, J.V., Dakal, T.C., Dhabhai, B., Dabbagh, O., Alsaif, H.S., Alkuraya, F.S., Maroofian, R., Houlden, H., Efthymiou, S., Dominik, N., Salpietro, V., Sultan, T., Haider, S., Bibi, F., Thiele, H., Hoefele, J., Riedhammer, K.M., Wagner, M., Guella, I., Demos, M., Keren, B., Buratti, J., Charles, P., Nava, C., Héron, D., Heide, S., Valkanas, E., Waddell, L.B., Jones, K.J., Oates, E.C., Cooper, S.T., MacArthur, D., Syrbe, S., Ziegler, A., Platzer, K., Okur, V., Chung, W.K., O'Shea, S.A., Alcalay, R., Fahn, S., Mark, P.R., Guerrini, R., Vetro, A., Hudson, B., Schnur, R.E., Hoganson, G.E., Burton, J.E., McEntagart, M., Lindenberg, T., Yilmaz, Ö., Odermatt, B., Pehlivan, D., Posey, J.E., Lupski, J.R., Reutter, H. (2021) Biallelic and monoallelic variants in PLXNA1 are implicated in a novel neurodevelopmental disorder with variable cerebral and eye anomalies. Genetics in medicine : official journal of the American College of Medical Genetics. 23(9):1715-1725
Rieke, J.M., Zhang, R., Braun, D., Yilmaz, Ö., Japp, A.S., Lopes, F.M., Pleschka, M., Hilger, A.C., Schneider, S., Newman, W.G., Beaman, G.M., Nordenskjöld, A., Ebert, A.K., Promm, M., Rösch, W.H., Stein, R., Hirsch, K., Schäfer, F.M., Schmiedeke, E., Boemers, T.M., Lacher, M., Kluth, D., Gosemann, J.H., Anderberg, M., Barker, G., Holmdahl, G., Läckgren, G., Keene, D., Cervellione, R.M., Giorgio, E., Di Grazia, M., Feitz, W.F.J., Marcelis, C.L.M., Van Rooij, I.A.L.M., Bökenkamp, A., Beckers, G.M.A., Keegan, C.E., Sharma, A., Dakal, T.C., Wittler, L., Grote, P., Zwink, N., Jenetzky, E., Brusco, A., Thiele, H., Ludwig, M., Schweizer, U., Woolf, A.S., Odermatt, B., Reutter, H. (2020) SLC20A1 Is Involved in Urinary Tract and Urorectal Development. Frontiers in cell and developmental biology. 8:567
Nagarajan, B., Harder, A., Japp, A., Häberlein, F., Mingardo, E., Kleinert, H., Yilmaz, Ö., Zoons, A., Rau, B., Christ, A., Kubitscheck, U., Eiberger, B., Sandhoff, R., Eckhardt, M., Hartmann, D., Odermatt, B. (2019) CNS myelin protein 36K regulates oligodendrocyte differentiation through Notch. Glia. 68(3):509-527
Kolvenbach, C.M., Dworschak, G.C., Frese, S., Japp, A.S., Schuster, P., Wenzlitschke, N., Yilmaz, Ö., Lopes, F.M., Pryalukhin, A., Schierbaum, L., van der Zanden, L.F.M., Kause, F., Schneider, R., Taranta-Janusz, K., Szczepańska, M., Pawlaczyk, K., Newman, W.G., Beaman, G.M., Stuart, H.M., Cervellione, R.M., Feitz, W.F.J., van Rooij, I.A.L.M., Schreuder, M.F., Steffens, M., Weber, S., Merz, W.M., Feldkötter, M., Hoppe, B., Thiele, H., Altmüller, J., Berg, C., Kristiansen, G., Ludwig, M., Reutter, H., Woolf, A.S., Hildebrandt, F., Grote, P., Zaniew, M., Odermatt, B., Hilger, A.C. (2019) Rare Variants in BNC2 Are Implicated in Autosomal-Dominant Congenital Lower Urinary-Tract Obstruction. American journal of human genetics. 104:994-1006
Yu, W.Q., El-Danaf, R.N., Okawa, H., Pacholec, J.M., Matti, U., Schwarz, K., Odermatt, B., Dunn, F.A., Lagnado, L., Schmitz, F., Huberman, A.D., Wong, R.O.L. (2018) Synaptic Convergence Patterns onto Retinal Ganglion Cells Are Preserved despite Topographic Variation in Pre- and Postsynaptic Territories. Cell Reports. 25:2017-2026.e3
Engerer, P., Suzuki, S.C., Yoshimatsu, T., Chapouton, P., Obeng, N., Odermatt, B., Williams, P.R., Misgeld, T., Godinho, L. (2017) Uncoupling of neurogenesis and differentiation during retinal development. The EMBO journal. 36(9):1134-1146
Ralser, D.J., Basmanav, F.B., Tafazzoli, A., Wititsuwannakul, J., Delker, S., Danda, S., Thiele, H., Wolf, S., Busch, M., Pulimood, S.A., Altmüller, J., Nürnberg, P., Lacombe, D., Hillen, U., Wenzel, J., Frank, J., Odermatt, B., Betz, R.C. (2017) Mutations in γ-secretase subunit-encoding PSENEN underlie Dowling-Degos disease associated with acne inversa. The Journal of Clinical Investigation. 127(4):1485-1490
Zhang, R., Knapp, M., Suzuki, K., Kajioka, D., Schmidt, J.M., Winkler, J., Yilmaz, Ö., Pleschka, M., Cao, J., Kockum, C.C., Barker, G., Holmdahl, G., Beaman, G., Keene, D., Woolf, A.S., Cervellione, R.M., Cheng, W., Wilkins, S., Gearhart, J.P., Sirchia, F., Di Grazia, M., Ebert, A.K., Rösch, W., Ellinger, J., Jenetzky, E., Zwink, N., Feitz, W.F., Marcelis, C., Schumacher, J., Martinón-Torres, F., Hibberd, M.L., Khor, C.C., Heilmann-Heimbach, S., Barth, S., Boyadjiev, S.A., Brusco, A., Ludwig, M., Newman, W., Nordenskjöld, A., Yamada, G., Odermatt, B., Reutter, H. (2017) ISL1 is a major susceptibility gene for classic bladder exstrophy and a regulator of urinary tract development. Scientific Reports. 7:42170
Pelassa, I., Zhao, C., Pasche, M., Odermatt, B., Lagnado, L. (2014) Synaptic vesicles are "primed" for fast clathrin-mediated endocytosis at the ribbon synapse. Frontiers in molecular neuroscience. 7:91
Baden, T., Nikolaev, A., Esposti, F., Dreosti, E., Odermatt, B., Lagnado, L. (2014) A synaptic mechanism for temporal filtering of visual signals. PLoS Biology. 12:e1001972
Nikolaev, A., Leung, K.M., Odermatt, B., and Lagnado, L. (2013) Synaptic mechanisms of adaptation and sensitization in the retina. Nature Neuroscience. 16(7):934-41
Odermatt, B., Nikolaev, A., and Lagnado, L. (2012) Encoding of luminance and contrast by linear and nonlinear synapses in the retina. Neuron. 73(4):758-773
Hunter, P.R., Nikolaou, N., Odermatt, B., Williams, P.R., Drescher, U., and Meyer, M.P. (2011) Localization of cadm2a and cadm3 proteins during development of the zebrafish nervous system. The Journal of comparative neurology. 519(11):2252-70
Dorostkar, M.M., Dreosti, E., Odermatt, B., and Lagnado, L. (2010) Computational processing of optical measurements of neuronal and synaptic activity in networks. Journal of Neuroscience Methods. 188(1):141-150
Dreosti, E., Odermatt, B., Dorostkar, M.M., and Lagnado, L. (2009) A genetically encoded reporter of synaptic activity in vivo. Nature Methods. 6(12):883-889
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