ZFIN ID: ZDB-LAB-200508-1
Kenmochi Lab
PI/Director: Kenmochi, Naoya
Contact Person: Uechi, Tamayo
Email: kenmochi@med.miyazaki-u.ac.jp
URL: http://www.med.miyazaki-u.ac.jp/home/kenmochi/en
Address: Frontier Science Research Center University of Miyazaki 5200 Kihara, Kiyotake, Miyazaki 889-1692
Country: Japan
Phone: +81-985-85-9084
Fax:
Line Designation: myz


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 1 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Uechi, Tamayo


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Basu, A., Yoshihama, M., Uechi, T., Kenmochi, N. (2020) Prokaryotic ribosomal RNA stimulates zebrafish embryonic innate immune system. BMC research notes. 13:6
Palasin, K., Uechi, T., Yoshihama, M., Srisowanna, N., Choijookhuu, N., Hishikawa, Y., Kenmochi, N., Chotigeat, W. (2019) Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a. Scientific Reports. 9:18130
Uechi, T., Kenmochi, N. (2019) Zebrafish Models of Diamond-Blackfan Anemia: A Tool for Understanding the Disease Pathogenesis and Drug Discovery. Pharmaceuticals (Basel, Switzerland). 12(4)
Toki, T., Yoshida, K., Wang, R., Nakamura, S., Maekawa, T., Goi, K., Katoh, M.C., Mizuno, S., Sugiyama, F., Kanezaki, R., Uechi, T., Nakajima, Y., Sato, Y., Okuno, Y., Sato-Otsubo, A., Shiozawa, Y., Kataoka, K., Shiraishi, Y., Sanada, M., Chiba, K., Tanaka, H., Terui, K., Sato, T., Kamio, T., Sakaguchi, H., Ohga, S., Kuramitsu, M., Hamaguchi, I., Ohara, A., Kanno, H., Miyano, S., Kojima, S., Ishiguro, A., Sugita, K., Kenmochi, N., Takahashi, S., Eto, K., Ogawa, S., Ito, E. (2018) De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome. American journal of human genetics. 103(3):440-447
Kurogi, K., Yoshihama, M., Williams, F.E., Kenmochi, N., Sakakibara, Y., Suiko, M., Liu, M.C. (2018) Identification of zebrafish steroid sulfatase and comparative analysis of the enzymatic properties with human steroid sulfatase. The Journal of steroid biochemistry and molecular biology. 185:110-117
Nagasawa, C., Ogren, A., Kibiryeva, N., Marshall, J., O'Brien, J.E., Kenmochi, N., Bittel, D.C. (2018) The Role of scaRNAs in Adjusting Alternative mRNA Splicing in Heart Development. Journal of cardiovascular development and disease. 5(2)
Chakraborty, A., Uechi, T., Nakajima, Y., Gazda, H.T., O'Donohue, M.F., Gleizes, P.E., Kenmochi, N. (2017) Cross talk between TP53 and c-Myc in the pathophysiology of Diamond-Blackfan anemia: Evidence from RPL11-deficient in vivo and in vitro models. Biochemical and Biophysical Research Communications. 495(2):1839-1845
Kurogi, K., Yoshihama, M., Horton, A., Schiefer, I.T., Krasowski, M.D., Hagey, L.R., Williams, F.E., Sakakibara, Y., Kenmochi, N., Suiko, M., Liu, M.C. (2017) Identification and characterization of 5α-cyprinol-sulfating cytosolic sulfotransferases (Sults) in the Zebrafish (Danio rerio). The Journal of steroid biochemistry and molecular biology. 174:120-127
Ikeda, F., Yoshida, K., Toki, T., Uechi, T., Ishida, S., Nakajima, Y., Sasahara, Y., Okuno, Y., Kanezaki, R., Terui, K., Kamio, T., Kobayashi, A., Fujita, T., Sato-Otsubo, A., Shiraishi, Y., Tanaka, H., Chiba, K., Muramatsu, H., Kanno, H., Ohga, S., Ohara, A., Kojima, S., Kenmochi, N., Miyano, S., Ogawa, S., Ito, E. (2017) Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia.. Haematologica. 102:e93-e96
Patil, P., Kibiryeva, N., Uechi, T., Marshall, J., O'Brien, J.E., Artman, M., Kenmochi, N., Bittel, D.C. (2015) scaRNAs Regulate Splicing and Vertebrate Heart Development. Biochimica et biophysica acta. Molecular basis of disease. 1852(8):1619-29
Wang, R., Yoshida, K., Toki, T., Sawada, T., Uechi, T., Okuno, Y., Sato-Otsubo, A., Kudo, K., Kamimaki, I., Kanezaki, R., Shiraishi, Y., Chiba, K., Tanaka, H., Terui, K., Sato, T., Iribe, Y., Ohga, S., Kuramitsu, M., Hamaguchi, I., Ohara, A., Hara, J., Goi, K., Matsubara, K., Koike, K., Ishiguro, A., Okamoto, Y., Watanabe, K., Kanno, H., Kojima, S., Miyano, S., Kenmochi, N., Ogawa, S., Ito, E. (2015) Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia. British journal of haematology. 168(6):854-64
Patil, P., Uechi, T., Kenmochi, N. (2015) Incomplete splicing of neutrophil-specific genes affects neutrophil development in a zebrafish model of poikiloderma with neutropenia. RNA Biology. 12:426-434
Yadav, G.V., Chakraborty, A., Uechi, T., and Kenmochi, N. (2014) Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish. The international journal of biochemistry & cell biology. 49:1-7
Higa-Nakamine, S., Suzuki, T., Uechi, T., Chakraborty, A., Nakajima, Y., Nakamura, M., Hirano, N., Suzuki, T., and Kenmochi, N. (2012) Loss of ribosomal RNA modification causes developmental defects in zebrafish. Nucleic acids research. 40(1):391-8
Torihara, H., Uechi, T., Chakraborty, A., Shinya, M., Sakai, N., and Kenmochi, N. (2011) Erythropoiesis failure due to RPS19 deficiency is independent of an activated Tp53 response in a zebrafish model of Diamond-Blackfan anaemia. British journal of haematology. 152(5):648-654
Ikeda, M., Andoo, A., Shimono, M., Takamatsu, N., Taki, A., Muta, K., Matsushita, W., Uechi, T., Matsuzaki, T., Kenmochi, N., Takata, K., Sasaki, S., Ito, K., and Ishibashi, K. (2011) The NPC motif of aquaporin-11, unlike the NPA motif of known aquaporins, is essential for full expression of molecular function. The Journal of biological chemistry. 286(5):3342-3350
Higa, S., and Kenmochi, N. (2009) Analysis of RNA modification in zebrafish. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 54(16 Suppl):2092-2097
Chakraborty, A., Uechi, T., Higa, S., Torihara, H., and Kenmochi, N. (2009) Loss of ribosomal protein L11 affects zebrafish embryonic development through a p53-dependent apoptotic response. PLoS One. 4(1):e4152
Uechi, T., Nakajima, Y., Chakraborty, A., Torihara, H., Higa, S., and Kenmochi, N. (2008) Deficiency of ribosomal protein S19 during early embryogenesis leads to reduction of erythrocytes in a zebrafish model of Diamond-Blackfan anemia. Human molecular genetics. 17(20):3204-3211
Uechi, T., Nakajima, Y., Nakao, A., Torihara, H., Chakraborty, A., Inoue, K., and Kenmochi, N. (2006) Ribosomal protein gene knockdown causes developmental defects in zebrafish. PLoS One. 1(1):e37