ZFIN ID: ZDB-LAB-191119-1
de la Pompa Lab
PI/Director: de la Pompa, José Luis
Contact Person: de la Pompa, José Luis
Email: jlpompa@cnic.es
URL: http://www.cnic.es/en/desarrollo/intercelular/index.php
Address: Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, 28029 Madrid
Country: Spain
Phone: +34-91-4531334
Fax: +34-91-4531240
Line Designation: cn


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 7 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Grego Bessa, Joaquín Jacob Post-Doc Luna Zurita, Luis Post-Doc Ferreira Oliveira, Vera Lúcia Research Staff
González Costa, Tamara Research Staff Grivas, Dimitrios Research Staff Macgrogan, Donal Research Staff
Piñeiro Sabarís, Rebeca Research Staff Prados Pinto, Belen Research Staff Salguero Jiménez, Alejandro Research Staff
Siguero Álvarez, Marcos Research Staff Torregrosa Carrión, Rebeca Research Staff Bou Pérez, Vanesa Technical Staff
Galicia Martín, Abel Technical Staff García Espada, Vanessa Technical Staff Lendínez González, Cristina Technical Staff
Méndez Peralta, Lucía Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Torregrosa-Carrión, R., Luna-Zurita, L., García-Marqués, F., D'Amato, G., Piñeiro-Sabarís, R., Bonzón-Kulichenko, E., Vázquez, J., de la Pompa, J.L. (2019) NOTCH activation promotes valve formation by regulating the endocardial secretome. Molecular & cellular proteomics : MCP. 18(9):1782-1795
Andrés-Delgado, L., Ernst, A., Galardi-Castilla, M., Bazaga, D., Peralta, M., Münch, J., González-Rosa, J.M., Marques, I., Tessadori, F., de la Pompa, J.L., Vermot, J., Mercader, N. (2019) Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells. Development (Cambridge, England). 146(13):
MacGrogan, D., Münch, J., de la Pompa, J.L. (2018) Notch and interacting signalling pathways in cardiac development, disease, and regeneration. Nature reviews. Cardiology. 15:685-704
Del Monte-Nieto, G., Ramialison, M., Adam, A.A.S., Wu, B., Aharonov, A., D'Uva, G., Bourke, L.M., Pitulescu, M.E., Chen, H., de la Pompa, J.L., Shou, W., Adams, R.H., Harten, S.K., Tzahor, E., Zhou, B., Harvey, R.P. (2018) Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 557(7705):439-445
Münch, J., Grivas, D., González-Rajal, Á., Torregrosa-Carrión, R., de la Pompa, J.L. (2017) Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart.. Development (Cambridge, England). 144(8):1425-1440
Münch, J., González-Rajal, A., and de la Pompa, J.L. (2013) Notch regulates blastema proliferation and prevents differentiation during adult zebrafish fin regeneration. Development (Cambridge, England). 140(7):1402-1411
Luxan, G., Casanova, J.C., Martinez-Poveda, B., Prados, B., D'Amato, G., Macgrogan, D., Gonzalez-Rajal, A., Dobarro, D., Torroja, C., Martinez, F., Izquierdo-García, J.L., Fernandez-Friera, L., Sabater-Molina, M., Kong, Y.Y., Pizarro, G., Ibañez, B., Medrano, C., García-Pavía, P., Gimeno, J.R., Monserrat, L., Jimenez-Borreguero, L.J., and de la Pompa, J.L. (2013) Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nature medicine. 19(2):193-201
Rodríguez, P., Higueras, M.A., González-Rajal, A., Alfranca, A., Fierro-Fernández, M., García-Fernández, R.A., Ruiz-Hidalgo, M.J., Monsalve, M., Rodríguez-Pascual, F., Redondo, J.M., de la Pompa, J.L., Laborda, J., and Lamas, S. (2012) The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis. Cardiovascular research. 93(2):232-241
Del Monte, G., Grego-Bessa, J., González-Rajal, A., Bolós, V., and De La Pompa, J.L. (2007) Monitoring Notch1 activity in development: Evidence for a feedback regulatory loop. Developmental dynamics : an official publication of the American Association of Anatomists. 236(9):2594-2614
Timmerman, L.A., Grego-Bessa, J., Raya, A., Bertran, E., Perez-Pomares, J.M., Diez, J., Aranda, S., Palomo, S., McCormick, F., Izpisúa Belmonte, J.C., and De La Pompa, J.L. (2004) Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes & Development. 18(1):99-115