ZFIN Lab: Minchin Lab

ZFIN ID: ZDB-LAB-170316-2

Minchin Lab

PI/Director:	Minchin, James
Contact Person:	Minchin, James
Email:	james.minchin@ed.ac.uk
URL:	http://minchinlab.org
Address:	BHF Centre for Cardiovascular Science University of Edinburgh The Queen's Medical Research Institute 47 Little France Crescent Edinburgh Scotland, UK EH16 4TJ
Country:	United Kingdom
Phone:	+44 (0)131 242 7930
Fax:
Line Designation:	ed

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Tandon, Panna Post-Doc

Wafer, Rebecca Graduate Student

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Loh, N.Y., Minchin, J.E.N., Pinnick, K.E., Verma, M., Todorčević, M., Denton, N., Moustafa, J.E., Kemp, J.P., Gregson, C.L., Evans, D.M., Neville, M.J., Small, K.S., McCarthy, M.I., Mahajan, A., Rawls, J.F., Karpe, F., Christodoulides, C. (2020) RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro. Nature communications. 11:2797

Elemans, L.M.H., Cervera, I.P., Riley, S.E., Wafer, R., Fong, R., Tandon, P., Minchin, J.E.N. (2019) Quantitative analyses of adiposity dynamics in zebrafish. Adipocyte. 8:330-338

van der Klaauw, A.A., Croizier, S., Mendes de Oliveira, E., Stadler, L.K.J., Park, S., Kong, Y., Banton, M.C., Tandon, P., Hendricks, A.E., Keogh, J.M., Riley, S.E., Papadia, S., Henning, E., Bounds, R., Bochukova, E.G., Mistry, V., O'Rahilly, S., Simerly, R.B., INTERVAL, UK10K Consortium, Minchin, J.E.N., Barroso, I., Jones, E.Y., Bouret, S.G., Farooqi, I.S. (2019) Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance. Cell. 176(4):729-742.e18

Minchin, J.E.N., Scahill, C.M., Staudt, N., Busch-Nentwich, E.M., Rawls, J.F. (2018) Deep phenotyping in zebrafish reveals genetic and diet-induced adiposity changes that may inform disease risk. Journal of Lipid Research. 59(8):1536-1545

Minchin, J.E.N., Rawls, J.F. (2017) Elucidating the role of plexin D1 in body fat distribution and susceptibility to metabolic disease using a zebrafish model system. Adipocyte. 6(4):277-283

Minchin, J.E., Rawls, J.F. (2017) A classification system for zebrafish adipose tissues. Disease models & mechanisms. 10(6):797-809

Wafer, R., Tandon, P., Minchin, J.E.N. (2017) The Role of Peroxisome Proliferator-Activated Receptor Gamma (PPARG) in Adipogenesis: Applying Knowledge from the Fish Aquaculture Industry to Biomedical Research.. Frontiers in endocrinology. 8:102

Minchin, J.E., Rawls, J.F. (2017) In vivo imaging and quantification of regional adiposity in zebrafish. Methods in cell biology. 138:3-27

Minchin, J.E., Dahlman, I., Harvey, C.J., Mejhert, N., Singh, M.K., Epstein, J.A., Arner, P., Torres-Vazquez, J., Rawls, J.F. (2015) Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue. Proceedings of the National Academy of Sciences of the United States of America. 112(14):4363-8

Minchin, J.E., Williams, V.C., Hinits, Y., Low, S., Tandon, P., Fan, C.M., Rawls, J.F., and Hughes, S.M. (2013) Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion. Development (Cambridge, England). 140(14):2972-2984

McMenamin, S.K., Minchin, J.E., Gordon, T.N., Rawls, J.F., and Parichy, D.M. (2013) Dwarfism and Increased Adiposity in the gh1 Mutant Zebrafish vizzini. Endocrinology. 154(4):1476-87

Minchin, J.E., and Rawls, J.F. (2011) In vivo Analysis of White Adipose Tissue in Zebrafish. Methods in cell biology. 105:63-86

Minchin, J.E., and Hughes, S.M. (2008) Sequential actions of Pax3 and Pax7 drive xanthophore development in zebrafish neural crest. Developmental Biology. 317(2):508-522

Hammond, C.L., Hinits, Y., Osborn, D.P., Minchin, J.E., Tettamanti, G., and Hughes, S.M. (2007) Signals and myogenic regulatory factors restrict pax3 and pax7 expression to dermomyotome-like tissue in zebrafish. Developmental Biology. 302(2):504-521