ZFIN ID: ZDB-LAB-170210-5
Xu Wang Lab
PI/Director: Wang, Xu
Contact Person: Wang, Xu
Email: wangxu2013@fudan.edu.cn
URL:
Address: Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education Department of Biochemistry and Molecular Biology School of Basic Medical Sciences Fudan University Mailbox 238, No.138 Yixueyuan Road, Shanghai, China 200032
Country: China
Phone: 86-021-54237092
Fax:
Line Designation: fdu


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 16 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Yang, Q., Wu, F., Mi, Y., Wang, F., Cai, K., Yang, X., Zhang, R., Liu, L., Zhang, Y., Wang, Y., Wang, X., Xu, M., Gui, Y., Li, Q. (2020) Aberrant expression of miR-29b-3p influences heart development and cardiomyocyte proliferation by targeting NOTCH2. Cell Proliferation. 53(3):e12764
Yao, Y., Wang, L., Wang, X. (2020) Modeling of Solid-Tumor Microenvironment in Zebrafish (Danio Rerio) Larvae. Advances in experimental medicine and biology. 1219:413-428
Liu, L., Fei, F., Zhang, R., Wu, F., Yang, Q., Wang, F., Sun, S., Zhao, H., Li, Q., Wang, L., Wang, Y., Gui, Y., Wang, X. (2019) Combinatorial genetic replenishments in myocardial and outflow tract tissues restore heart function in tnnt2 mutant zebrafish. Biology Open. 8(12):
Fei, F., Wang, L., Sun, S., Lv, K., Yao, Y., Wang, J., Yu, M., Wang, X. (2019) Transgenic Strategies to Generate Heterogeneous Hepatic Cancer Models in Zebrafish. Journal of molecular cell biology. 11(11):1021-1023
Xia, W., Hu, J., Ma, J., Huang, J., Wang, X., Jiang, N., Zhang, J., Ma, Z., Ma, D. (2019) Novel TRRAP mutation causes autosomal dominant non-syndromic hearing loss. Clinical genetics. 96(4):300-308
Wang, L., Chen, H., Fei, F., He, X., Sun, S., Lv, K., Yu, B., Long, J., Wang, X. (2019) Patient-derived Heterogeneous Xenograft Model of Pancreatic Cancer Using Zebrafish Larvae as Hosts for Comparative Drug Assessment. Journal of visualized experiments : JoVE. (146):
Wang, F., Yang, Q., Wu, F., Zhang, Y., Sun, S., Wang, X., Gui, Y., Li, Q. (2019) Identification of a 42-bp heart-specific enhancer of the notch1b gene in zebrafish embryos. Developmental dynamics : an official publication of the American Association of Anatomists. 248(6):426-436
Yang, Q., Yan, C., Wang, X., Gong, Z. (2019) Leptin induces muscle wasting in kras-driven hepatocellular carcinoma (HCC) model in zebrafish. Disease models & mechanisms. 12(2):
Lv, K., Fei, F., Wang, X. (2019) A hint from zebrafish models of hepatic tumorigenesis: Targeting stearoyl-CoA desaturase. Oncotarget. 10:924-925
Zhang, R., He, J., Wang, X., Pan, W., Cao, Y., Zu, Y., Jiang, Q., Du, J., Zhong, T.P. (2018) Report of the Fifth Zebrafish Research Conference of China. Zebrafish. 16(1):128-134
Yao, Y., Sun, S., Wang, J., Fei, F., Dong, Z., Ke, A.W., He, R., Wang, L., Zhang, L., Ji, M.B., Li, Q., Yu, M., Shi, G.M., Fan, J., Gong, Z., Wang, X. (2018) Canonical Wnt signaling remodels lipid metabolism in zebrafish hepatocytes following Ras oncogenic insult. Cancer research. 78(19):5548-5560
Xia, W., Hu, J., Liu, F., Ma, J., Sun, S., Zhang, J., Jin, K., Huang, J., Jiang, N., Wang, X., Li, W., Ma, Z., Ma, D. (2017) New role of LRP5, associated with non-syndromic autosomal recessive hereditary hearing loss. Human Mutation. 38(10):1421-1431
Yao, Y., Sun, S., Fei, F., Wang, J., Wang, Y., Zhang, R., Wu, J., Liu, L., Liu, X., Cui, Z., Li, Q., Yu, M., Dang, Y., Wang, X. (2017) Screening in larval zebrafish reveals tissue-specific distributions of fifteen fluorescent compounds. Disease models & mechanisms. 10(9):1155-1164
Zhou, S.R., Guo, L., Wang, X., Liu, Y., Peng, W.Q., Liu, Y., Wei, X.B., Dou, X., Ding, M., Lei, Q.Y., Qian, S.W., Li, X., Tang, Q.Q. (2017) Acetylation of Cavin-1 Promotes Lipolysis in White Adipose Tissue. Molecular and cellular biology. 37(16):e00058-17
Zhang, R., Liu, L., Yao, Y., Fei, F., Wang, F., Yang, Q., Gui, Y., Wang, X. (2017) High Resolution Imaging of DNA Methylation Dynamics using a Zebrafish Reporter. Scientific Reports. 7:5430
Fei, F., Sun, S.Y., Yao, Y.X., Wang, X. (2017) [Generation and phenotype analysis of zebrafish mutations of obesity-related genes lepr and mc4r]. Sheng li xue bao : [Acta physiologica Sinica]. 69:61-69
Ma, Z., Xia, W., Liu, F., Ma, J., Sun, S., Zhang, J., Jiang, N., Wang, X., Hu, J., Ma, D. (2017) SLC44A4 Mutation Causes Autosomal Dominant Hereditary Postlingual Non-syndromic Mid-frequency Hearing loss. Human molecular genetics. 26(2):383-394
Jiang, L., Yin, M., Xu, J., Jia, M., Sun, S., Wang, X., Zhang, J., Meng, D. (2017) The Transcription Factor Bach1 Suppresses the Developmental Angiogenesis of Zebrafish. Oxidative medicine and cellular longevity. 2017:2143875
Wu, J., Yang, Y., Sun, C., Sun, S., Li, Q., Yao, Y., Fei, F., Lu, L., Chang, Z., Zhang, W., Wang, X., Luo, F. (2017) Disruption of the gaa Gene in Zebrafish Fails to Generate the Phenotype of Classical Pompe Disease. DNA and cell biology. 36:10-17
He, Y., Cai, C., Sun, S., Wang, X., Li, W., Li, H. (2016) Effect of JNK inhibitor SP600125 on hair cell regeneration in zebrafish (Danio rerio) larvae. Oncotarget. 7(32):51640-51650
Liu, F., Xia, W., Hu, J., Wang, Y., Yang, F., Sun, S., Zhang, J., Jiang, N., Wang, H., Tian, W., Wang, X., Ma, D. (2015) Solute Carrier Family 26 Member a2 (slc26a2) Regulates Otic Development and Hair Cell Survival in Zebrafish. PLoS One. 10:e0136832
Guo, M., Wei, H., Hu, J., Sun, S., Long, J., Wang, X. (2015) U0126 inhibits pancreatic cancer progression via the KRAS signaling pathway in a zebrafish xenotransplantation model. Oncology reports. 34(2):699-706
Liu, F., Yang, F., Wen, D., Xia, W., Hao, L., Hu, J., Zong, J., Shen, X., Ma, J., Jiang, N., Sun, S., Zhang, J., Wang, H., Wang, X., Ma, Z., Ma, D. (2015) Grhl1 deficiency affects inner ear development in zebrafish. The International journal of developmental biology. 59(10-11-12):417-423
Shen, X., Liu, F., Wang, Y., Wang, H., Ma, J., Xia, W., Zhang, J., Jiang, N., Sun, S., Wang, X., Ma, D. (2015) Down-regulation of msrb3 and destruction of normal auditory system development through hair cell apoptosis in zebrafish. The International journal of developmental biology. 59:195-203
Sang, Q., Zhang, J., Feng, R., Wang, X., Li, Q., Zhao, X., Xing, Q., Chen, W., Du, J., Sun, S., Chai, R., Jin, L., He, L., Li, H., Wang, L. (2014) Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium, and hearing ability in zebrafish: Implications for a role in the recessive hearing impairment DFNB42. Human molecular genetics. 23(23):6201-11
Wang, X., Kopinke, D., Lin, J., McPherson, A.D., Duncan, R.N., Otsuna, H., Moro, E., Hoshijima, K., Grunwald, D.J., Argenton, F., Chien, C.B., Murtaugh, L.C., and Dorsky, R.I. (2012) Wnt signaling regulates postembryonic hypothalamic progenitor differentiation. Developmental Cell. 23(3):624-636
Lin, J., Wang, X., and Dorsky, R.I. (2011) Progenitor expansion in apc mutants is mediated by Jak/Stat signaling. BMC Developmental Biology. 11(1):73
Gribble, S.L., Kim, H.S., Bonner, J., Wang, X., and Dorsky, R.I. (2009) Tcf3 inhibits spinal cord neurogenesis by regulating sox4a expression. Development (Cambridge, England). 136(5):781-789
Wang, X., Lee, J.E., and Dorsky, R.I. (2009) Identification of wnt-responsive cells in the zebrafish hypothalamus. Zebrafish. 6(1):49-58
Bonkowsky, J.L., Wang, X., Fujimoto, E., Lee, J.E., Chien, C.B., and Dorsky, R.I. (2008) Domain-specific regulation of foxP2 CNS expression by lef1. BMC Developmental Biology. 8:103