ZFIN ID: ZDB-LAB-170210-2
Ruilin Zhang Lab
PI/Director: Zhang, Ruilin
Contact Person: Zhang, Ruilin
Email: zhangruilin@fudan.edu.cn
URL:
Address: Fudan University School of Life Sciences 2005 Songhu Road, Yangpu District, Shanghai 200438, CHINA
Country: China
Phone: 86-21-51630677
Fax: 86-21-51630677
Line Designation: fdu


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 1 genomic features


STATEMENT OF RESEARCH INTERESTS
Use zebrafish as model organism to study cardiovascular development and disease, regenerative medicine, signal transduction, cell fate determination and differentiation.


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Li, X., Lu, Q., Peng, Y., Geng, F., Shao, X., Zhou, H., Cao, Y., Zhang, R. (2020) Primary cilia mediate Klf2-dependant Notch activation in regenerating heart. Protein & cell. 11(6):433-445
Gálvez-Santisteban, M., Chen, D., Zhang, R., Serrano, R., Nguyen, C., Zhao, L., Nerb, L., Masutani, E.M., Vermot, J., Burns, C.G., Burns, C.E., Del Álamo, J.C., Chi, N.C. (2019) Hemodynamic-mediated endocardial signaling controls in vivo myocardial reprogramming. eLIFE. 8:
Chang, Y., Geng, F., Hu, Y., Ding, Y., Zhang, R. (2019) Zebrafish cysteine and glycine-rich protein 3 is essential for mechanical stability in skeletal muscles. Biochemical and Biophysical Research Communications. 511(3):604-611
Zhang, R., He, J., Wang, X., Pan, W., Cao, Y., Zu, Y., Jiang, Q., Du, J., Zhong, T.P. (2018) Report of the Fifth Zebrafish Research Conference of China. Zebrafish. 16(1):128-134
Yang, D., Zheng, X., Chen, S., Wang, Z., Xu, W., Tan, J., Hu, T., Hou, M., Wang, W., Gu, Z., Wang, Q., Zhang, R., Zhang, Y., Liu, Q. (2018) Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish. Nature communications. 9:3052
Cao, X., Li, C., Xiao, S., Tang, Y., Huang, J., Zhao, S., Li, X., Li, J., Zhang, R., Yu, W. (2017) Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage. Proceedings of the National Academy of Sciences of the United States of America. 114(4):687-692
Han, P., Bloomekatz, J., Ren, J., Zhang, R., Grinstein, J.D., Zhao, L., Burns, C.G., Burns, C.E., Anderson, R.M., Chi, N.C. (2016) Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis. Nature. 534:700-4
Dickover, M., Hegarty, J.M., Ly, K., Lopez, D., Yang, H., Zhang, R., Tedeschi, N., Hsiai, T.K., Chi, N.C. (2014) The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. Developmental Biology. 389:182-91
Zhang, R., Han, P., Yang, H., Ouyang, K., Lee, D., Lin, Y.F., Ocorr, K., Kang, G., Chen, J., Stainier, D.Y., Yelon, D., and Chi, N.C. (2013) In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature. 498(7455):497-501
Dickover, M.S., Zhang, R., Han, P., and Chi, N.C. (2013) Zebrafish cardiac injury and regeneration models: a noninvasive and invasive in vivo model of cardiac regeneration. Methods in molecular biology (Clifton, N.J.). 1037:463-473
Zhang, R., Yang, J., Zhu, J., and Xu, X. (2009) Depletion of zebrafish Tcap leads to muscular dystrophy via disrupting sarcomere-membrane interaction, not sarcomere assembly. Human molecular genetics. 18(21):4130-4140
Sun, X., Hoage, T., Bai, P., Ding, Y., Chen, Z., Zhang, R., Huang, W., Jahangir, A., Paw, B., Li, Y.G., and Xu, X. (2009) Cardiac hypertrophy involves both myocyte hypertrophy and hyperplasia in anemic zebrafish. PLoS One. 4(8):e6596
Huang, W., Zhang, R., and Xu, X. (2009) Myofibrillogenesis in the Developing Zebrafish Heart: A Functional Study of tnnt2. Developmental Biology. 331(2):237-249
Zhang, R., and Xu, X. (2009) Transient and transgenic analysis of the zebrafish ventricular myosin heavy chain (vmhc) promoter: An inhibitory mechanism of ventricle-specific gene expression. Developmental dynamics : an official publication of the American Association of Anatomists. 238(6):1564-1573
Zhang, R. (2009) Molecular genetics of zebrafish Tcap : a causative gene for muscular dystrophy and cardiomyopathy. Ph.D. Thesis. :173p
Sun, X., Zhang, R., Lin, X., and Xu, X. (2008) Wnt3a Regulates the Development of Cardiac Neural Crest Cells by Modulating Expression of Cysteine-Rich Intestinal Protein 2 in Rhombomere 6. Circulation research. 102(7):831-839