ZFIN Lab: Jiu-Lin Du Lab

ZFIN ID: ZDB-LAB-151217-1

Jiu-Lin Du Lab

PI/Director:	Du, Jiu Lin
Contact Person:	Ji-Wen, Bu
Email:	jwbu@ion.ac.cn
URL:
Address:	Institute of Neuroscience, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China
Country:	China
Phone:	86-21-54920706
Fax:	86-21-54921735
Line Designation:	ion

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 28 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Peng, Xiao-Lan Post-Doc	Zhang, He-Fei Post-Doc	Bai-Bing, Zhang Graduate Student
Chang-Mei, Zhang Graduate Student	Chen, Min-Jia Graduate Student	Chen, Yin Graduate Student
Hua-Xing, Zi Graduate Student	Li, Fu-Lin Graduate Student	Li, Hong-Yu Graduate Student
Ting-Ting, Liu Graduate Student	Wei-Yu, Chen Graduate Student	Xie, Jin-Ze Graduate Student
Yan, Yong Graduate Student	Yu-Fan, Wang Graduate Student	Shi, Yi-Song Technical Staff
Ji-Wen, Bu Administrative Staff	Chun-Feng, Shang	Rong-Wei, Zhang

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Du, X.F., Li, F.N., Peng, X.L., Xu, B., Zhang, Y., Li, G., Liu, T., Li, Y., Wang, H., Yan, J., Du, J.L. (2023) Circadian regulation of developmental synaptogenesis via the hypocretinergic system. Nature communications. 14:31953195

Wu, Z., He, K., Chen, Y., Li, H., Pan, S., Li, B., Liu, T., Xi, F., Deng, F., Wang, H., Du, J., Jing, M., Li, Y. (2021) A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo. Neuron. 110(5):770-782.e5

Zhang, H., Wang Haifang, H., Shen, X., Jia, X., Yu, S., Qiu, X., Wang, Y., Du, J., Yan, J., He, J. (2021) The landscape of regulatory genes in brain-wide neuronal phenotypes of a vertebrate brain. eLIFE. 10:

Xu, D., Wang, B., Xu, B., Yin, C., Ning, L., Li, X., Du, J., Wang, Y. (2021) Midazolam Exposure Impedes Oligodendrocyte Development via the Translocator Protein and Impairs Myelination in Larval Zebrafish. Molecular neurobiology. 59(1):93-106

Jiang, W., Liu, C., Deng, M., Wang, F., Ren, X., Fan, Y., Du, J., Wang, Y. (2020) H₂S promotes developmental brain angiogenesis via the NOS/NO pathway in zebrafish. Stroke and vascular neurology. 6(2):244-251

Gu, S., Li, J., Li, S., Cao, J., Bu, J., Ren, Y., Du, W., Chen, Z., Xu, C., Wang, M., Jiang, L., Huang, C., Du, J. (2020) Efficient replacement of long DNA fragments via non-homologous end joining at non-coding regions. Journal of molecular cell biology. 13(1):75-77

Liu, T.T., Du, X.F., Zhang, B.B., Zi, H.X., Yan, Y., Yin, J.A., Hou, H., Gu, S.Y., Chen, Q., Du, J.L. (2020) Piezo1-Mediated Ca²⁺ Activities Regulate Brain Vascular Pathfinding during Development. Neuron. 108(1):180-192.e5

Li, J., Li, H.Y., Gu, S.Y., Zi, H.X., Jiang, L., Du, J.L. (2019) One-step generation of zebrafish carrying a conditional knockout-knockin visible switch via CRISPR/Cas9-mediated intron targeting. Science China. Life sciences. 63(1):59-67

Wang, R., Zhang, H., Du, J., Xu, J. (2019) Heat resilience in embryonic zebrafish revealed by an in vivo stress granule reporter. Journal of Cell Science. 132(20):

Zhang, R.W., Du, W.J., Prober, D.A., Du, J.L. (2019) Müller Glial Cells Participate in Retinal Waves via Glutamate Transporters and AMPA Receptors. Cell Reports. 27:2871-2880.e2

Feng, J., Zhang, C., Lischinsky, J.E., Jing, M., Zhou, J., Wang, H., Zhang, Y., Dong, A., Wu, Z., Wu, H., Chen, W., Zhang, P., Zou, J., Hires, S.A., Zhu, J.J., Cui, G., Lin, D., Du, J., Li, Y. (2019) A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine. Neuron. 102(4):745-761.e8

Jin, W., Dai, Y., Li, F., Zhu, L., Huang, Z., Liu, W., Li, J., Zhang, M., Du, J., Zhang, W., Wen, Z. (2019) Dysregulation of Microglial Function Contributes to Neuronal Impairment in Mcoln1a-Deficient Zebrafish. iScience. 13:391-401

Chen, W.Y., Peng, X.L., Deng, Q.S., Chen, M.J., Du, J.L., Zhang, B.B. (2019) Role of Olfactorily Responsive Neurons in the Right Dorsal Habenula - Ventral Interpeduncular Nucleus Pathway in Food-Seeking Behaviors of Larval Zebrafish. Neuroscience. 404:259-267

Zhang, R., He, J., Wang, X., Pan, W., Cao, Y., Zu, Y., Jiang, Q., Du, J., Zhong, T.P. (2018) Report of the Fifth Zebrafish Research Conference of China. Zebrafish. 16(1):128-134

Jiao, Z.F., Shang, C.F., Wang, Y.F., Yang, Z., Yang, C., Li, F.N., Xie, J.Z., Pan, J.W., Fu, L., Du, J.L. (2018) All-optical imaging and manipulation of whole-brain neuronal activities in behaving larval zebrafish. Biomedical Optics Express. 9:6154-6169

Du, X.F., Xu, B., Zhang, Y., Chen, M.J., Du, J.L. (2018) A transgenic zebrafish model for in vivo long-term imaging of retinotectal synaptogenesis. Scientific Reports. 8:14077

Du, W.J., Zhang, R.W., Li, J., Zhang, B.B., Peng, X.L., Cao, S., Yuan, J., Yuan, C.D., Yu, T., Du, J.L. (2018) The Locus Coeruleus Modulates Intravenous General Anesthesia of Zebrafish via a Cooperative Mechanism. Cell Reports. 24:3146-3155.e3

Sun, F., Zeng, J., Jing, M., Zhou, J., Feng, J., Owen, S.F., Luo, Y., Li, F., Wang, H., Yamaguchi, T., Yong, Z., Gao, Y., Peng, W., Wang, L., Zhang, S., Du, J., Lin, D., Xu, M., Kreitzer, A.C., Cui, G., Li, Y. (2018) A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice. Cell. 174:481-496.e19

Zhang, Y., Xu, B., Chen, Q., Yan, Y., Du, J., Du, X. (2018) Apoptosis of Endothelial Cells Contributes to Brain Vessel Pruning of Zebrafish During Development. Frontiers in molecular neuroscience. 11:222

Tao, R., Shi, M., Zou, Y., Cheng, D., Wang, Q., Liu, R., Wang, A., Zhu, J., Deng, L., Hu, H., Chen, X., Du, J., Zhu, W., Zhao, Y., Yang, Y. (2018) Multicoloured fluorescent indicators for live-cell and in vivo imaging of inorganic mercury dynamics. Free radical biology & medicine. 121:26-37

Zhang, B.B., Du, J.L. (2017) [The structure and function of habenula]. Sheng li xue bao : [Acta physiologica Sinica]. 69:623-636

Cong, L., Wang, Z., Chai, Y., Hang, W., Shang, C., Yang, W., Bai, L., Du, J., Wang, K., Wen, Q. (2017) Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (Danio rerio).. eLIFE. 6

Xu, D.J., Wang, B., Zhao, X., Zheng, Y., Du, J.L., Wang, Y.W. (2017) General anesthetics protects against cardiac arrest-induced brain injury by inhibiting calcium wave propagation in zebrafish. Molecular brain. 10:44

Xu, B., Zhang, Y., Du, X.F., Li, J., Zi, H.X., Bu, J.W., Yan, Y., Han, H., Du, J.L. (2017) Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity. Cell Research. 27(7):882-897

Zhang, B.B., Yao, Y.Y., Zhang, H.F., Kawakami, K., Du, J.L. (2017) Left Habenula Mediates Light-Preference Behavior in Zebrafish via an Asymmetrical Visual Pathway. Neuron. 93(4):914-928.e4

Zhang, R.W., Li, X.Q., Kawakami, K., Du, J.L. (2016) Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors. Nature communications. 7:12650

Wang, M.S., Zhang, R.W., Su, L.Y., Li, Y., Peng, M.S., Liu, H.Q., Zeng, L., Irwin, D.M., Du, J.L., Yao, Y.G., Wu, D.D., Zhang, Y.P. (2016) Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication. Cell Research. 26:556-73

Yao, Y., Li, X., Zhang, B., Yin, C., Liu, Y., Chen, W., Zeng, S., Du, J. (2016) Visual Cue-Discriminative Dopaminergic Control of Visuomotor Transformation and Behavior Selection. Neuron. 89(3):598-612

Li, Y., Du, X., Pei, G., Du, J., Zhao, J. (2016) β-Arrestin1 Regulates Morphology and Dynamics of Microglia in Zebrafish in Vivo. The European journal of neuroscience. 43(2):131-8

Zhang, R.W., Du, J.L. (2016) In Vivo Whole-Cell Patch-Clamp Recording in the Zebrafish Brain. Methods in molecular biology (Clifton, N.J.). 1451:281-91

Shang, C.F., Li, X.Q., Yin, C., Liu, B., Wang, Y.F., Zhou, Z., Du, J.L. (2015) Amperometric Monitoring of Sensory-Evoked Dopamine Release in Awake Larval Zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:15291-4

Li, J., Zhang, B.B., Ren, Y.G., Gu, S.Y., Xiang, Y.H., Huang, C., Du, J.L. (2015) Intron targeting-mediated and endogenous gene integrity-maintaining knockin in zebrafish using the CRISPR/Cas9 system. Cell Research. 25(5):634-7

Li, Y., Li, G., Görling, B., Luy, B., Du, J., Yan, J. (2015) Integrative Analysis of Circadian Transcriptome and Metabolic Network Reveals the Role of De Novo Purine Synthesis in Circadian Control of Cell Cycle. PLoS Computational Biology. 11:e1004086

Sang, Q., Zhang, J., Feng, R., Wang, X., Li, Q., Zhao, X., Xing, Q., Chen, W., Du, J., Sun, S., Chai, R., Jin, L., He, L., Li, H., Wang, L. (2014) Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium, and hearing ability in zebrafish: Implications for a role in the recessive hearing impairment DFNB42. Human molecular genetics. 23(23):6201-11

Liu, J., Liu, Y., Bu, W., Bu, J., Sun, Y., Du, J., Shi, J. (2014) Ultrasensitive Nanosensors Based on Upconversion Nanoparticles for Selective Hypoxia Imaging in Vivo Upon Near-Infrared Excitation. Journal of the American Chemical Society. 136(27):9701-9

Li, H., Yue, R., Wei, B., Gao, G., Du, J., Pei, G. (2014) Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. The EMBO journal. 33(12):1383-96

Li, Y., Du, X.F., and Du, J.L. (2013) Resting microglia respond to and regulate neuronal activity in vivo. Communicative & integrative biology. 6(4):e24493

Zhang, R.W., Zhang, S.Y., and Du, J.L. (2013) KCC2-dependent subcellular E_Cl difference of ON-OFF retinal ganglion cells in larval zebrafish. Frontiers in neural circuits. 7:103

Li, X.Q., and Du, J.L. (2013) Visual system and prey capture behavior of larval zebrafish. Yi chuan = Hereditas. 35(4):468-476

Liu, Y., Xu, X.H., Chen, Q., Wang, T., Deng, C.Y., Song, B.L., Du, J.L., and Luo, Z.G. (2013) Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development. Nature communications. 4:2005

Li, Y., Li, G., Wang, H., Du, J., and Yan, J. (2013) Analysis of a gene regulatory cascade mediating circadian rhythm in zebrafish. PLoS Computational Biology. 9(2):e1002940

Li, Y., Du, X.F., Liu, C.S., Wen, Z.L., and Du, J.L. (2012) Reciprocal Regulation between Resting Microglial Dynamics and Neuronal Activity In Vivo. Developmental Cell. 23(6):1189-1202

Cai, G., Zhu, J., Shen, C., Cui, Y., Du, J., and Chen, X. (2012) The Effects of Cobalt on the Development, Oxidative Stress, and Apoptosis in Zebrafish Embryos. Biological trace element research. 150(1-3):200-207

Mu, Y., Li, X.Q., Zhang, B., and Du, J.L. (2012) Visual Input Modulates Audiomotor Function via Hypothalamic Dopaminergic Neurons through a Cooperative Mechanism. Neuron. 75(4):688-699

Wei, H.P., Yao, Y.Y., Zhang, R.W., Zhao, X.F., and Du, J.L. (2012) Activity-induced long-term potentiation of excitatory synapses in developing zebrafish retina in vivo. Neuron. 75(3):479-489

Li, Y., Huang, W., Huang, S., Du, J., and Huang, C. (2012) Screening of anti-cancer agent using zebrafish: Comparison with the MTT assay. Biochemical and Biophysical Research Communications. 422(1):85-90

Yue, R., Li, H., Liu, H., Li, Y., Wei, B., Gao, G., Jin, Y., Liu, T., Wei, L., Du, J., and Pei, G. (2012) Thrombin Receptor Regulates Hematopoiesis and Endothelial-to-Hematopoietic Transition. Developmental Cell. 22(5):1092-1100

Chen, Q., Jiang, L., Li, C., Hu, D., Bu, J.W., Cai, D., and Du, J.L. (2012) Haemodynamics-driven developmental pruning of brain vasculature in zebrafish. PLoS Biology. 10(8):e1001374

Han, Y., Mu, Y., Li, X., Xu, P., Tong, J., Liu, Z., Ma, T., Zeng, G., Yang, S., Du, J., and Meng, A. (2011) Grhl2 deficiency impairs otic development and hearing ability in a zebrafish model of the progressive dominant hearing loss DFNA28. Human molecular genetics. 20(16):3213-26

Xu, D.J., Bu, J.W., Gu, S.Y., Xia, Y.M., Du, J.L., and Wang, Y.W. (2011) Celecoxib Impairs Heart Development via Inhibiting Cyclooxygenase-2 Activity in Zebrafish Embryos. Anesthesiology. 114(2):391-400

Feng, Y., Yan, T., Zheng, J., Ge, X., Mu, Y., Zhang, Y., Wu, D., Du, J.L., and Zhai, Q. (2010) Overexpression of Wld(s) or Nmnat2 in mauthner cells by single-cell electroporation delays axon degeneration in live zebrafish. Journal of neuroscience research. 88(15):3319-3327

Zhang, R.W., Wei, H.P., Xia, Y.M., and Du, J.L. (2010) Development of light response and GABAergic excitation-to-inhibition switch in zebrafish retinal ganglion cells. The Journal of physiology. 588(Pt 14):2557-2569

Yu, P.C., Gu, S.Y., Bu, J.W., and Du, J.L. (2010) TRPC1 Is Essential for In Vivo Angiogenesis in Zebrafish. Circulation research. 106(7):1221-1232

Huang, C., Gu, S., Yu, P., Yu, F., Feng, C., Gao, N., and Du, J. (2010) Deficiency of smarcal1 causes cell cycle arrest and developmental abnormalities in zebrafish. Developmental Biology. 339(1):89-100