ZFIN ID: ZDB-LAB-151008-3
White Lab
PI/Director: White, Richard
Contact Person: White, Richard
Email: whiter@mskcc.org
URL: http://www.mskcc.org/research-areas/labs/richard-white
Address: Memorial Sloan Kettering Cancer Center Weill Cornell Medical College 1275 York Avenue, Box 424 New York, N.Y. 10075
Country: United States
Phone: 646-888-3415
Fax: 646-422-0231
Line Designation: mk


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 4 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Kim, I.S., Heilmann, S., Kansler, E.R., Zhang, Y., Zimmer, M., Ratnakumar, K., Bowman, R.L., Simon-Vermot, T., Fennell, M., Garippa, R., Lu, L., Lee, W., Hollmann, T., Xavier, J.B., White, R.M. (2017) Microenvironment-derived factors driving metastatic plasticity in melanoma. Nature communications. 8:14343
Kansler, E.R., Verma, A., Langdon, E.M., Simon-Vermot, T., Yin, A., Lee, W., Attiyeh, M., Elemento, O., White, R.M. (2017) Melanoma genome evolution across species. BMC Genomics. 18:136
White, R.M. (2016) Genomic Approaches to Zebrafish Cancer. Advances in experimental medicine and biology. 916:125-45
Wojciechowska, S., van Rooijen, E., Ceol, C., Patton, E.E., White, R.M. (2016) Generation and analysis of zebrafish melanoma models. Methods in cell biology. 134:531-49
Tan, J.L., Fogley, R.D., Flynn, R.A., Ablain, J., Yang, S., Saint-André, V., Fan, Z.P., Do, B.T., Laga, A.C., Fujinaga, K., Santoriello, C., Greer, C.B., Kim, Y.J., Clohessy, J.G., Bothmer, A., Pandell, N., Avagyan, S., Brogie, J.E., van Rooijen, E., Hagedorn, E.J., Shyh-Chang, N., White, R.M., Price, D.H., Pandolfi, P.P., Peterlin, B.M., Zhou, Y., Kim, T.H., Asara, J.M., Chang, H.Y., Young, R.A., Zon, L.I. (2016) Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62:34-46
Brocal, I., White, R.J., Dooley, C.M., Carruthers, S.N., Clark, R., Hall, A., Busch-Nentwich, E.M., Stemple, D.L., Kettleborough, R.N. (2016) Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening in zebrafish. BMC Genomics. 17:259
Heilmann, S., Ratnakumar, K., Langdon, E., Kansler, E., Kim, I., Campbell, N.R., Perry, E., McMahon, A., Kaufman, C., van Rooijen, E., Lee, W., Iacobuzio-Donahue, C., Hynes, R., Zon, L., Xavier, J., White, R.M. (2015) A quantitative system for studying metastasis using transparent zebrafish. Cancer research. 75(20):4272-82
White, R.M. (2015) Cross-species oncogenomics using zebrafish models of cancer. Current opinion in genetics & development. 30:73-9
Yen, J., White, R.M., Stemple, D.L. (2013) Zebrafish models of cancer: progress and future challenges. Current opinion in genetics & development. 24C:38-45
Paik, E.J., Mahony, S., White, R.M., Price, E.N., Dibiase, A., Dorjsuren, B., Mosimann, C., Davidson, A.J., Gifford, D., and Zon, L.I. (2013) A cdx4-sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem Cell Reports. 1(5):425-436
White, R., Rose, K., and Zon, L. (2013) Zebrafish cancer: the state of the art and the path forward. Nature reviews. Cancer. 3(9):624-636
Harvey, S.A., Sealy, I., Kettleborough, R., Fenyes, F., White, R., Stemple, D., and Smith, J.C. (2013) Identification of the zebrafish maternal and paternal transcriptomes. Development (Cambridge, England). 140(13):2703-2710
Tamplin, O.J., White, R.M., Jing, L., Kaufman, C.K., Lacadie, S.A., Li, P., Taylor, A.M., and Zon, L.I. (2012) Small molecule screening in zebrafish: swimming in potential drug therapies. Wiley Interdisciplinary Reviews: Developmental Biology. 1(3):459-468
Zhang, L., Alt, C., Li, P., White, R.M., Zon, L.I., Wei, X., and Lin, C.P. (2011) An optical platform for cell tracking in adult zebrafish. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 81(2):176-182
Taylor, A.M., Humphries, J.M., White, R.M., Murphey, R.D., Burns, C.E., and Zon, L.I. (2011) Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation. Experimental hematology. 40(3):228-237
White, R.M., Cech, J., Ratanasirintrawoot, S., Lin, C.Y., Rahl, P.B., Burke, C.J., Langdon, E., Tomlinson, M.L., Mosher, J., Kaufman, C., Chen, F., Long, H.K., Kramer, M., Datta, S., Neuberg, D., Granter, S., Young, R.A., Morrison, .S, Wheeler, G.N., and Zon, L.I. (2011) DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature. 471(7339):518-522
Jiang, N., Weinstein, J.A., Penland, L., White, R.A., Fisher, D.S., and Quake, S.R. (2011) Determinism and stochasticity during maturation of the zebrafish antibody repertoire. Proc. Natl. Acad. Sci. USA. 108(13):5348-53
Li, P., White, R.M., and Zon, L.I. (2011) Transplantation in zebrafish. Meth. Cell. Biol.. 105:403-417
Feng, H., Stachura, D.L., White, R.M., Gutierrez, A., Zhang, L., Sanda, T., Jette, C.A., Testa, J.R., Neuberg, D.S., Langenau, D.M., Kutok, J.L., Zon, L.I., Traver, D., Fleming, M.D., Kanki, J.P., and Look, A.T. (2010) T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell. 18(4):353-366
Pugach, E.K., Li, P., White, R., and Zon, L. (2009) Retro-orbital injection in adult zebrafish. Journal of visualized experiments : JoVE. (34)
Dovey, M., White, R.M., and Zon, L.I. (2009) Oncogenic NRAS Cooperates with p53 Loss to Generate Melanoma in Zebrafish. Zebrafish. 6(4):397-404
Weinstein, J.A., Jiang, N., White, R.A. 3rd, Fisher, D.S., and Quake, S.R. (2009) High-throughput sequencing of the zebrafish antibody repertoire. Science (New York, N.Y.). 324(5928):807-810
Kaufman, C.K., White, R.M., and Zon, L. (2009) Chemical genetic screening in the zebrafish embryo. Nature Protocols. 4(10):1422-1432
Ceol, C.J., Houvras, Y., White, R.M., and Zon, L.I. (2008) Melanoma biology and the promise of zebrafish. Zebrafish. 5(4):247-255
Sessa, A.K., White, R., Houvras, Y., Burke, C., Pugach, E., Baker, B., Gilbert, R., Look, A.T., and Zon, L.I. (2008) The effect of a depth gradient on the mating behavior, oviposition site preference, and embryo production in the zebrafish, Danio rerio. Zebrafish. 5(4):335-339
White, R.M., and Zon, L.I. (2008) Melanocytes in Development, Regeneration, and Cancer. Cell Stem Cell. 3(3):242-252
White, R.M., Sessa, A., Burke, C., Bowman, T., LeBlanc, J., Ceol, C., Bourque, C., Dovey, M., Goessling, W., Burns, C.E., and Zon, L.I. (2008) Mechanism unknown: prostaglandin E2 may improve HSC therapies. Cell Stem Cell. 2(2):183-189
White, R.M., Sessa, A., Burke, C., Bowman, T., LeBlanc, J., Ceol, C. Bourque, C., Dovey, M., Goessling, W., Burns, C.E., and Zon, L.I. (2008) Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis. Cell Stem Cell. 2(2):183-189