ZFIN ID: ZDB-LAB-131204-1
Peng Huang Lab
PI/Director: Huang, Peng
Contact Person: Huang, Peng
Email: huangp@ucalgary.ca
URL: http://people.ucalgary.ca/~huangp/index.html
Address: Department of Biochemistry and Molecular Biology University of Calgary Health Sciences Centre, Rm 2209 3330 Hospital Drive N.W. Calgary, Alberta, Canada T2N 4N1
Country: Canada
Phone: 403-220-3388 (lab)
Fax:
Line Designation: ca


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 7 genomic features


STATEMENT OF RESEARCH INTERESTS
We are interested in understanding 1) how cell signaling pathways regulate progenitor cell differentiation and 2) how tissue integrity is maintained.


LAB MEMBERS
Jacobs, Craig Graduate Student Ma, Roger Graduate Student Kocha, Katrinka Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Jacobs, C.T., Huang, P. (2019) Notch signalling maintains Hedgehog responsiveness via a Gli-dependent mechanism during spinal cord patterning in zebrafish. eLIFE. 8:
Sharma, P., Ruel, T.D., Kocha, K.M., Liao, S., Huang, P. (2019) Single cell dynamics of embryonic muscle progenitor cells in zebrafish. Development (Cambridge, England). 146(14):
Ma, R.C., Jacobs, C.T., Sharma, P., Kocha, K.M., Huang, P. (2018) Stereotypic generation of axial tenocytes from bipartite sclerotome domains in zebrafish. PLoS Genetics. 14:e1007775
Bremer, K., Kocha, K.M., Snider, T., Moyes, C.D. (2016) Sensing and responding to energetic stress: The role of the AMPK-PGC1α-NRF1 axis in control of mitochondrial biogenesis in fish. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 199:4-12
Hanwell, D., Hutchinson, S.A., Collymore, C., Bruce, A.E., Louis, R., Ghalami, A., Allison, W.T., Ekker, M., Eames, B.F., Childs, S., Kurrasch, D.M., Gerlai, R., Thiele, T., Scott, I., Ciruna, B., Dowling, J.J., McFarlane, S., Huang, P., Wen, X.Y., Akimenko, M.A., Waskiewicz, A.J., Drapeau, P., Babiuk, L.A., Dragon, D., Smida, A., Buret, A.G., O'Grady, E., Wilson, J., Sowden-Plunkett, L., Tropepe, V. (2016) Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus. Zebrafish. 13 Suppl 1:S153-63
Hudish, L.I., Galati, D.F., Ravanelli, A.M., Pearson, C.G., Huang, P., Appel, B. (2016) miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling. Development (Cambridge, England). 143(13):2292-304
Kocha, K.M., Reilly, K., Porplycia, D.S., McDonald, J., Snider, T., Moyes, C.D. (2015) Evolution of the oxygen sensitivity of cytochrome c oxidase subunit 4. American journal of physiology. Regulatory, integrative and comparative physiology. 308(4):R305-20
Gagnon, J.A., Valen, E., Thyme, S.B., Huang, P., Ahkmetova, L., Pauli, A., Montague, T.G., Zimmerman, S., Richter, C., Schier, A.F. (2014) Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs. PLoS One. 9:e98186
Sittaramane, V., Pan, X., Glasco, D.M., Huang, P., Gurung, S., Bock, A., Li, S., Wang, H., Kawakami, K., Matise, M.P., and Chandrasekhar, A. (2013) The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function. Developmental Biology. 382(2):400-412
Xiong, F., Tentner, A.R., Huang, P., Gelas, A., Mosaliganti, K.R., Souhait, L., Rannou, N., Swinburne, I.A., Obholzer, N.D., Cowgill, P.D., Schier, A.F., and Megason, S.G. (2013) Specified neural progenitors sort to form sharp domains after noisy shh signaling. Cell. 153(3):550-561
Stooke-Vaughan, G.A., Huang, P., Hammond, K.L., Schier, A.F., and Whitfield, T.T. (2012) The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle. Development (Cambridge, England). 139(10):1777-1787
Huang, P., Xiong, F., Megason, S.G., and Schier, A.F. (2012) Attenuation of notch and hedgehog signaling is required for fate specification in the spinal cord. PLoS Genetics. 8(6):e1002762
Duggan, A.T., Kocha, K.M., Monk, C.T., Bremer, K., and Moyes, C.D. (2011) Coordination of cytochrome c oxidase gene expression in the remodelling of skeletal muscle. The Journal of experimental biology. 214(11):1880-1887
Huang, P., and Schier, A.F. (2009) Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development (Cambridge, England). 136(18):3089-3098
Mao, J., McGlinn, E., Huang, P., Tabin, C.J., and McMahon, A.P. (2009) Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb. Developmental Cell. 16(4):600-606