ZFIN Lab: Hitchcock Lab

ZFIN ID: ZDB-LAB-130415-1

Hitchcock Lab

PI/Director:	Hitchcock, Peter
Contact Person:	Nagashima, Mikiko
Email:	mikiko@umich.edu
URL:
Address:	7434 Brehm Tower 1000 Wall Street Ann Arbor, MI 48105
Country:	United States
Phone:	734.763.8170
Fax:	734.936.7231
Line Designation:	mi

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 9 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Nagashima, Mikiko Research Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Lyu, P., Iribarne, M., Serjanov, D., Zhai, Y., Hoang, T., Campbell, L.J., Boyd, P., Palazzo, I., Nagashima, M., Silva, N.J., Hitchcock, P.F., Qian, J., Hyde, D.R., Blackshaw, S. (2023) Common and divergent gene regulatory networks control injury-induced and developmental neurogenesis in zebrafish retina. Nature communications. 14:84778477

Magner, E., Sandoval-Sanchez, P., Kramer, A.C., Thummel, R., Hitchcock, P.F., Taylor, S.M. (2022) Disruption of miR-18a Alters Proliferation, Photoreceptor Replacement Kinetics, Inflammatory Signaling, and Microglia/Macrophage Numbers During Retinal Regeneration in Zebrafish. Molecular neurobiology. 59(5):2910-2931

Kapuria, S., Bai, H., Fierros, J., Huang, Y., Ma, F., Yoshida, T., Aguayo, A., Kok, F., Wiens, K.M., Yip, J.K., McCain, M.L., Pellegrini, M., Nagashima, M., Hitchcock, P.F., Mochizuki, N., Lawson, N.D., Harrison, M.M.R., Lien, C.L. (2022) Heterogeneous pdgfrβ+ cells regulate coronary vessel development and revascularization during heart regeneration. Development (Cambridge, England). 149(4):

Nagashima, M., Hitchcock, P.F. (2021) Inflammation Regulates the Multi-Step Process of Retinal Regeneration in Zebrafish. Cells. 10(4):

Nagashima, M., Hitchcock, P.F. (2020) Whole-mount Immunohistochemistry of Adult Zebrafish Retina for Advanced Imaging. Bio-protocol. 10:e3848

Nunley, H., Nagashima, M., Martin, K., Lorenzo Gonzalez, A., Suzuki, S.C., Norton, D.A., Wong, R.O.L., Raymond, P.A., Lubensky, D.K. (2020) Defect patterns on the curved surface of fish retinae suggest a mechanism of cone mosaic formation. PLoS Computational Biology. 16:e1008437

Ang, N.B., Saera-Vila, A., Walsh, C., Hitchcock, P.F., Kahana, A., Thummel, R., Nagashima, M. (2020) Midkine-a functions as a universal regulator of proliferation during epimorphic regeneration in adult zebrafish. PLoS One. 15:e0232308

Lahne, M., Nagashima, M., Hyde, D.R., Hitchcock, P.F. (2020) Reprogramming Müller Glia to Regenerate Retinal Neurons. Annual review of vision science. 6:171-193

Silva, N.J., Nagashima, M., Li, J., Kakuk-Atkins, L., Ashrafzadeh, M., Hyde, D.R., Hitchcock, P.F. (2020) Inflammation and matrix metalloproteinase 9 (Mmp-9) regulate photoreceptor regeneration in adult zebrafish. Glia. 68(7):1445-1465

Nagashima, M., D'Cruz, T.S., Danku, A.E., Hesse, D., Sifuentes, C., Raymond, P.A., Hitchcock, P.F. (2019) Midkine-a is required for cell cycle progression of Müller glia glia during neuronal regeneration in the vertebrate retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 40(6):1232-1247

Taylor, S.M., Giuffre, E., Moseley, P., Hitchcock, P.F. (2019) The microRNA, miR-18a, regulates NeuroD and photoreceptor differentiation in the retina of the zebrafish. Developmental Neurobiology. 79(2):202-219

Fu, J., Nagashima, M., Guo, C., Raymond, P.A., Wei, X. (2018) Novel Animal Model of Crumbs-Dependent Progressive Retinal Degeneration That Targets Specific Cone Subtypes. Investigative ophthalmology & visual science. 59:505-518

Nagashima, M., Hadidjojo, J., Barthel, L.K., Lubensky, D.K., Raymond, P.A. (2017) Anisotropic Müller glial scaffolding supports a multiplex lattice mosaic of photoreceptors in zebrafish retina. Neural Development. 12:20

Walsh, C.E., Hitchcock, P.F. (2017) Progranulin regulates neurogenesis in the developing vertebrate retina. Developmental Neurobiology. 77(9):1114-1129

Taylor, S.M., Alvarez-Delfin, K., Saade, C.J., Thomas, J.L., Thummel, R., Fadool, J.M., Hitchcock, P.F. (2015) The bHLH Transcription Factor NeuroD Governs Photoreceptor Genesis and Regeneration Through Delta-Notch Signaling. Investigative ophthalmology & visual science. 56:7496-7515

Gramage, E., D'Cruz, T., Taylor, S., Thummel, R., Hitchcock, P.F. (2015) Midkine-a Protein Localization in the Developing and Adult Retina of the Zebrafish and Its Function During Photoreceptor Regeneration. PLoS One. 10:e0121789

Ogai, K., Kuwana, A., Hisano, S., Nagashima, M., Koriyama, Y., Sugitani, K., Mawatari, K., Nakashima, H., Kato, S. (2014) Upregulation of Leukemia Inhibitory Factor (LIF) during the Early Stage of Optic Nerve Regeneration in Zebrafish. PLoS One. 9:e106010

Gramage, E., Li, J., and Hitchcock, P. (2014) The expression and function of midkine in the vertebrate retina. British journal of pharmacology. 171(4):913-923

Raymond, P.A., Colvin, S.M., Jabeen, Z., Nagashima, M., Barthel, L.K., Hadidjojo, J., Popova, L., Pejaver, V.R., and Lubensky, D.K. (2014) Patterning the cone mosaic array in zebrafish retina requires specification of ultraviolet-sensitive cones. PLoS One. 9(1):e85325

Nagashima, M., Barthel, L.K., and Raymond, P.A. (2013) A self-renewing division of zebrafish Muller glial cells generates neuronal progenitors that require N-cadherin to regenerate retinal neurons. Development (Cambridge, England). 140(22):4510-4521

Huang, T., Cui, J., Li, L., Hitchcock, P.F., and Li, Y. (2012) The role of microglia in the neurogenesis of zebrafish retina. Biochemical and Biophysical Research Communications. 421(2):214-220

Fujikawa, C., Nagashima, M., Mawatari, K., and Kato, S. (2012) HSP70 Gene Expression in the Zebrafish Retina After Optic Nerve Injury: A Comparative Study Under Heat Shock Stresses. Advances in experimental medicine and biology. 723:663-668

Nagashima, M., Fujikawa, C., Mawatari, K., Mori, Y., and Kato, S. (2011) HSP70, the earliest-induced gene in the zebrafish retina during optic nerve regeneration: Its role in cell survival. Neurochemistry international. 58(8):888-895

Craig, S.E., Thummel, R., Ahmed, H., Vasta, G.R., Hyde, D., and Hitchcock, P.F. (2010) The Zebrafish Galectin Drgal1-L2 Is Expressed by Proliferating Müller Glia and Photoreceptor Progenitors and Regulates the Regeneration of Rod Photoreceptors. Investigative ophthalmology & visual science. 51(6):3244-3252

Nagashima, M., Saito, J., Mawatari, K., Mori, Y., Matsukawa, T., Koriyama, Y., and Kato, S. (2010) A hypoplastic retinal lamination in the purpurin knock down embryo in zebrafish. Advances in experimental medicine and biology. 664:517-524

Nagashima, M., Mawatari, K., Tanaka, M., Higashi, T., Saito, H., Muramoto, K., Matsukawa, T., Koriyama, Y., Sugitani, K., and Kato, S. (2009) Purpurin is a key molecule for cell differentiation during the early development of zebrafish retina. Brain research. 1302:54-63

Ochocinska, M.J., and Hitchcock, P.F. (2009) NeuroD regulates proliferation of photoreceptor progenitors in the retina of the zebrafish. Mechanisms of Development. 126(3-4):128-141

Kaneda, M., Nagashima, M., Nunome, T., Muramatsu, T., Yamada, Y., Kubo, M., Muramoto, K., Matsukawa, T., Koriyama, Y., Sugitani, K., Vachkov, I.H., Mawatari, K., and Kato, S. (2008) Changes of phospho-growth-associated protein 43 (phospho-GAP43) in the zebrafish retina after optic nerve injury: A long-term observation. Neuroscience research. 61(3):281-288

Tanaka, M., Murayama, D., Nagashima, M., Higashi, T., Mawatari, K., Matsukawa, T., and Kato, S. (2007) Purpurin expression in the zebrafish retina during early development and after optic nerve lesion in adults. Brain research. 1153(1):34-42

Ochocinska, M.J., and Hitchcock, P.F. (2007) Dynamic expression of the basic helix-loop-helix transcription factor neuroD in the rod and cone photoreceptor lineages in the retina of the embryonic and larval zebrafish. The Journal of comparative neurology. 501(1):1-12

Hitchcock, P.F., and Raymond, P.A. (2004) The Teleost Retina as a Model for Developmental and Regeneration Biology. Zebrafish. 1(3):257-271