ZFIN ID: ZDB-LAB-120613-1
Betsholtz Lab
PI/Director: Betsholtz, Christer
Contact Person: Ando, Koji
Email: kando.nieve12@gmail.com
URL: http://www.igp.uu.se/research/vascular-biology/christer-betsholtz/
Address: Rudbeck Laboratory, 751 85 Uppsala
Country: Sweden
Phone: +46 (0) 18 471 4816
Fax:
Line Designation: uu


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 2 genomic features


STATEMENT OF RESEARCH INTERESTS
Angiogenesis and vascular permeability regulation
Endothelial cells and pericytes
Blood-brain barrier
Kidney glomerulus development, function and disease
Podocytes, their gene expression and transcriptional regulation


LAB MEMBERS
Ebarasi, Lwaki Post-Doc Gaengel, Konstantin Post-Doc Raschperger, Elisabeth Post-Doc
Ando, Koji


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Wang, G., Muhl, L., Padberg, Y., Dupont, L., Peterson-Maduro, J., Stehling, M., le Noble, F., Colige, A., Betsholtz, C., Schulte-Merker, S., van Impel, A. (2020) Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis. Nature communications. 11:2724
Ando, K., Wang, W., Peng, D., Chiba, A., Lagendijk, A., Barske, L., Crump, J.G., Stainier, D.Y.R., Lendahl, U., Koltowska, K., Hogan, B.M., Fukuhara, S., Mochizuki, N., Betsholtz, C. (2019) Peri-arterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling. Development (Cambridge, England). 146(2):
Kotini, M.P., Mäe, M.A., Belting, H.G., Betsholtz, C., Affolter, M. (2018) Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour. Vascular Pharmacology. 112:8-16
Perisic, L., Rodriguez, P.Q., Hultenby, K., Sun, Y., Lal, M., Betsholtz, C., Uhlén, M., Wernerson, A., Hedin, U., Pikkarainen, T., Tryggvason, K., Patrakka, J. (2015) Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin. PLoS One. 10:e0122067
Kok, F.O., Shin, M., Ni, C., Gupta, A., Grosse, A.S., van Impel, A., Kirchmaier, B.C., Peterson-Maduro, J., Kourkoulis, G., Male, I., DeSantis, D.F., Sheppard-Tindell, S., Ebarasi, L., Betsholtz, C., Schulte-Merker, S., Wolfe, S.A., Lawson, N.D. (2015) Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish. Developmental Cell. 32(1):97-108
Ebarasi, L., Ashraf, S., Bierzynska, A., Gee, H.Y., McCarthy, H.J., Lovric, S., Sadowski, C.E., Pabst, W., Vega-Warner, V., Fang, H., Koziell, A., Simpson, M.A., Dursun, I., Serdaroglu, E., Levy, S., Saleem, M.A., Hildebrandt, F., Majumdar, A. (2015) Defects of CRB2 Cause Steroid-Resistant Nephrotic Syndrome. American journal of human genetics. 96(1):153-61
He, B., Ebarasi, L., Zhao, Z., Guo, J., Ojala, J.R., Hultenby, K., De Val, S., Betsholtz, C., Tryggvason, K. (2014) Lmx1b and FoxC Combinatorially Regulate Podocin Expression in Podocytes. Journal of the American Society of Nephrology : JASN. 25(12):2764-77
Haas, U., Raschperger, E., Hamberg, M., Samuelsson, B., Tryggvason, K., and Haeggström, J.Z. (2011) Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development. Proceedings of the National Academy of Sciences of the United States of America. 108(51):20479-84
Nishibori, Y., Katayama, K., Parikka, M., Oddsson, A., Nukui, M., Hultenby, K., Wernerson, A., He, B., Ebarasi, L., Raschperger, E., Norlin, J., Uhlén, M., Patrakka, J., Betsholtz, C., and Tryggvason, K. (2011) Glcci1 Deficiency Leads to Proteinuria. Journal of the American Society of Nephrology : JASN. 22(11):2037-46
He, B., Ebarasi, L., Hultenby, K., Tryggvason, K., and Betsholtz, C. (2011) Podocin-Green Fluorescence Protein Allows Visualization and Functional Analysis of Podocytes. Journal of the American Society of Nephrology : JASN. 22(6):1019-1023
Raschperger, E., Neve, E.P., Wernerson, A., Hultenby, K., Pettersson, R.F., and Majumdar, A. (2008) The coxsackie and adenovirus receptor (CAR) is required for renal epithelial differentiation within the zebrafish pronephros. Developmental Biology. 313(1):455-464