ZFIN ID: ZDB-LAB-110302-2
Wenqing Lab
PI/Director: Zhang, Wenqing
Contact Person: Liu, Wei
Email: wweiweiliu@163.com
URL:
Address: 7 floor, life science building, Southern Medical University,1838North Guangzhou Avenue, Baiyun District, Guangzhou, China.
Country: China
Phone: +86 020 6164 7050
Fax: +86 020 6164 7050
Line Designation: sm


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show first 50 of 54 genomic features


STATEMENT OF RESEARCH INTERESTS
Research interests: hematopoietic development, disease modeling and drug screening.


LAB MEMBERS
Chi, Yali Graduate Student Fang, Xiao Graduate Student Huang, Zhibin Graduate Student
Liu, Wei Graduate Student Wang, Kun Graduate Student Xiong, Xiaojie Graduate Student
Xu, Mengchang Graduate Student Zhang, Zili Graduate Student Zhao, Lingfeng Graduate Student
Ma, Ning Research Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Liu, J., Liao, G., Tu, H., Huang, Y., Peng, T., Xu, Y., Chen, X., Huang, Z., Zhang, Y., Meng, X., Zou, F. (2019) A protective role of autophagy in Pb-induced developmental neurotoxicity in zebrafish. Chemosphere. 235:1050-1058
Gan, L., Zheng, Y., Deng, L., Sun, P., Ye, J., Wei, X., Liu, F., Yu, L., Ye, W., Fan, C., Liu, J., Zhang, W. (2019) Diterpenoid Lactones with Anti-Inflammatory Effects from the Aerial Parts of Andrographis paniculata. Molecules. 24(15)
Xu, M., Ye, Y., Ye, Z., Xu, S., Liu, W., Xu, J., Zhang, Y., Liu, Q., Huang, Z., Zhang, W. (2019) Human BCR/ABL1 induces chronic myeloid leukemia-like disease in zebrafish. Haematologica. 105(3):674-686
Wang, T., Yan, B., Lou, L., Lin, X., Yu, T., Wu, S., Lu, Q., Liu, W., Huang, Z., Zhang, M., Zhang, W., Wen, Z. (2019) Nlrc3-like is required for microglia maintenance in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 46(6):291-299
Wang, L., Gao, S., Wang, H., Xue, C., Liu, X., Yuan, H., Wang, Z., Chen, S., Chen, Z., de Thé, H., Zhang, Y., Zhang, W., Zhu, J., Zhou, J. (2019) Interferon regulatory factor 2 binding protein 2b regulates neutrophil versus macrophage fate during zebrafish definitive myelopoiesis. Haematologica. 105(2):325-337
Zhang, A., Wu, M., Tan, J., Yu, N., Xu, M., Yu, X., Liu, W., Zhang, Y. (2019) Establishment of a zebrafish hematological disease model induced by 1,4-benzoquinone. Disease models & mechanisms. 12(3):
Jin, W., Dai, Y., Li, F., Zhu, L., Huang, Z., Liu, W., Li, J., Zhang, M., Du, J., Zhang, W., Wen, Z. (2019) Dysregulation of Microglial Function Contributes to Neuronal Impairment in Mcoln1a-Deficient Zebrafish. iScience. 13:391-401
Chi, Y., Huang, Z., Chen, Q., Xiong, X., Chen, K., Xu, J., Zhang, Y., Zhang, W. (2018) Loss of runx1 function results in B cell immunodeficiency but not T cell in adult zebrafish.. Open Biology. 8(7):
Lian, J., Chen, J., Wang, K., Zhao, L., Meng, P., Yang, L., Wei, J., Ma, N., Xu, J., Zhang, W., Zhang, Y. (2018) Alas1 is essential for neutrophil maturation in zebrafish. Haematologica. 103(11):1785-1795
He, S., Chen, J., Jiang, Y., Wu, Y., Zhu, L., Jin, W., Zhao, C., Yu, T., Wang, T., Wu, S., Lin, X., Qu, J.Y., Wen, Z., Zhang, W., Xu, J. (2018) Adult zebrafish Langerhans cells arise from hematopoietic stem/progenitor cells. eLIFE. 7
Zhang, Z., Liu, W., Zhao, L., Huang, Z., Chen, X., Ma, N., Xu, J., Zhang, W., Zhang, Y. (2017) Rb1 promotes T cell maturation from premature apoptosis by inhibiting E2F1. Development (Cambridge, England). 145(1)
Tu, H., Peng, T., Liu, J., Chen, X., Fan, C., Huang, Z., Zhang, Y., Zou, F., Meng, X. (2017) Role of neurexin2a in lead-induced locomotor defect in developing zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 194:167-175
Lin, H., Zhou, Z., Zhong, W., Huang, P., Ma, N., Zhang, Y., Zhou, C., Lai, Y., Huang, S., An, H., Sun, X., Gao, L., Lv, Z. (2017) Naringenin inhibits alcoholic injury by improving lipid metabolism and reducing apoptosis in zebrafish larvae. Oncology reports. 38(5):2877-2884
Yang, L., Zhou, X., Huang, W., Fang, Q., Hu, J., Yu, L., Ma, N., Zhang, W. (2017) Protective Effect of Phillyrin on Lethal LPS-Induced Neutrophil Inflammation in Zebrafish. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 43:2074-2087
Di, Q., Lin, Q., Huang, Z., Chi, Y., Chen, X., Zhang, W., Zhang, Y. (2017) Zebrafish nephrosin helps host defence against Escherichia coli infection.. Open Biology. 7(8)
Tu, H., Fan, C., Chen, X., Liu, J., Wang, B., Huang, Z., Zhang, Y., Meng, X., Zou, F. (2017) Effects of cadmium, manganese and lead on locomotor activity and neurexin2a expression in zebrafish. Environmental toxicology and chemistry. 36(8):2147-2154
Li, R., Liao, G., Yin, G., Wang, B., Yan, M., Lin, X., Zhang, W., Chen, X., Du, S., Yuan, Y. (2017) Ionizing Radiation Blocks Hair Cell Regeneration in Zebrafish Lateral Line Neuromasts by Preventing Wnt Signaling. Molecular neurobiology. 55(2):1639-1651
Deng, M., Zhang, Y., Quan, X., Na, C., Chen, S., Liu, W., Han, S., Masunaga, S. (2017) Acute toxicity reduction and toxicity identification in pigment-contaminated wastewater during anaerobic-anoxic-oxic (A/A/O) treatment process. Chemosphere. 168:1285-1292
Wu, Y., Su, G., Tang, S., Liu, W., Ma, Z., Zheng, X., Liu, H., Yu, H. (2017) The combination of in silico and in vivo approaches for the investigation of disrupting effects of tris (2-chloroethyl) phosphate (TCEP) toward core receptors of zebrafish. Chemosphere. 168:122-130
Xiong, F., Ji, Z., Liu, Y., Zhang, Y., Hu, L., Yang, Q., Qiu, Q., Zhao, L., Chen, D., Tian, Z., Shang, X., Zhang, L., Wei, X., Liu, C., Yu, Q., Zhang, M., Cheng, J., Xiong, J., Li, D., Wu, X., Yuan, H., Zhang, W., Xu, X. (2017) Mutation in SSUH2 Causes Autosomal Dominant Dentin Dysplasia Type I. Human Mutation. 38(1):95-104
Zhou, Z., Zhong, W., Lin, H., Huang, P., Ma, N., Zhang, Y., Zhou, C., Lai, Y., Huang, S., Huang, S., Gao, L., Lv, Z. (2017) Hesperidin Protects against Acute Alcoholic Injury through Improving Lipid Metabolism and Cell Damage in Zebrafish Larvae. Evidence-based complementary and alternative medicine : eCAM. 2017:7282653
Dai, Y., Zhu, L., Huang, Z., Zhou, M., Jin, W., Liu, W., Xu, M., Yu, T., Zhang, Y., Wen, Z., Liao, W., Zhang, W. (2016) Cebpα is essential for the embryonic myeloid progenitor and neutrophil maintenance in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 43(10):593-600
Liu, W., Song, H., Li, A., Du, X., Liu, Y., He, Y., Zhang, Q., Qi, J. (2016) Functional characterization of the Japanese flounder (Paralichthys olivaceus) Sox2 gene promoter. Fish physiology and biochemistry. 42(5):1275-85
Yang, Q., Chen, D., Xiong, F., Chen, D., Liu, C., Liu, Y., Yu, Q., Xiong, J., Liu, J., Li, K., Zhao, L., Ye, Y., Zhou, H., Hu, L., Tian, Z., Shang, X., Zhang, L., Wei, X., Zhou, W., Li, D., Zhang, W., Xu, X. (2016) A splicing mutation in VPS4B causes dentin dysplasia I. Journal of Medical Genetics. 53(9):624-33
Jin, H., Huang, Z., Chi, Y., Wu, M., Zhou, R., Zhao, L., Xu, J., Zhen, F., Lan, Y., Li, L., Zhang, W., Wen, Z., Zhang, Y. (2016) cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish. Blood. 128(3):415-26
Zhang, C., Zhang, W., Lu, Y., Yan, X., Yan, X., Zhu, X., Liu, W., Yang, Y., Zhou, T. (2016) NudC regulates actin dynamics and ciliogenesis by stabilizing cofilin 1. Cell Research. 26(2):239-53
Zheng, X.C., Liu, L., Dai, W.C., Wang, K.Y., Chen, X.H., Zhao, L.F., Huang, Z.B., Hou, J.L. (2016) [Establishment of a diet-induced obesity model in zebrafish larvae]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 36:20-5
Guo, P., Huang, Z., Tao, T., Chen, X., Zhang, W., Zhang, Y., Lin, C. (2015) Zebrafish as a model for studying the developmental neurotoxicity of propofol. Journal of applied toxicology : JAT. 35(12):1511-9
Hao, K., Li, Y., Feng, J., Zhang, W., Zhang, Y., Ma, N., Zeng, Q., Pang, H., Wang, C., Xiao, L., He, X. (2015) Ozone promotes regeneration by regulating the inflammatory response in zebrafish. International Immunopharmacology. 28(1):369-75
Shi, X., He, B.L., Ma, A.C., Guo, Y., Chi, Y., Man, C.H., Zhang, W., Zhang, Y., Wen, Z., Cheng, T., Leung, A.Y. (2015) Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish. Blood. 125(19):2974-84
Wang, K., Fang, X., Ma, N., Lin, Q., Huang, Z., Liu, W., Xu, M., Chen, X., Zhang, W., Zhang, Y. (2015) Myeloperoxidase-deficient Zebrafish show an Augmented Inflammatory Response to Challenge with Candida albicans. Fish & shellfish immunology. 44(1):109-16
Liu, X., Wang, W., Samarsky, D., Liu, L., Xu, Q., Zhang, W., Zhu, G., Wu, P., Zuo, X., Deng, H., Zhang, J., Wu, Z., Chen, X., Zhao, L., Qiu, Z., Zhang, Z., Zeng, Q., Yang, W., Zhang, B., Ji, A. (2014) Tumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA. Nucleic acids research. 42(18):11805-17
Wang, J.H., Zhao, L.F., Lin, P., Su, X.R., Chen, S.J., Huang, L.Q., Wang, H.F., Zhang, H., Hu, Z.F., Yao, K.T., Huang, Z.X. (2014) GenCLiP 2.0: a web server for functional clustering of genes and construction of molecular networks based on free terms. Bioinformatics (Oxford, England). 30(17):2534-6
Wang, K., Huang, Z., Zhao, L., Liu, W., Chen, X., Meng, P., Lin, Q., Chi, Y., Xu, M., Ma, N., Zhang, Y., and Zhang, W. (2012) Large-scale forward genetic screening analysis of development of hematopoiesis in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 39(9):473-480
Yan, G., Liu, W., Dai, Z.X., Wang, K., Liu, J., Zhao, L.F., Huang, Z.B., Chen, X.H., Ma, N., Meng, P., Xu, M.C., Wen, Z.L., and Zhang, W.Q. (2011) Study of a new zebrafish mutant defective in primitive myelopoiesis. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 31(5):755-760
Du, L., Xu, J., Li, X., Ma, N., Liu, Y., Peng, J., Osato, M., Zhang, W., and Wen, Z. (2011) Rumba and Haus3 are essential factors for the maintenance of hematopoietic stem/progenitor cells during zebrafish hematopoiesis. Development (Cambridge, England). 138(4):619-629
Ma, N., Huang, Z., Chen, X., He, F., Wang, K., Liu, W., Zhao, L., Xu, X., Liao, W., Ruan, H., Luo, S., and Zhang, W. (2011) Characterization of a Weak Allele of Zebrafish cloche Mutant. PLoS One. 6(11):e27540
Ma, N., Huo, Z.J., Yan, G., Huang, H.H., Luo, S.Q., and Zhang, W.Q. (2010) Positional cloning of a novel allele of zebrafish cloche mutant. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 30(3):458-462