ZFIN ID: ZDB-LAB-110119-1
Alsina Lab
PI/Director: Alsina, Berta
Contact Person: Sas, Miquel
Email: miquel.sas@upf.edu
URL: http://www.upf.edu/devbiol/projectes/Alsina_lab.html
Address: Laboratory of Developmental Biology Universitat Pompeu Fabra-PRBB Dr. Aiguader 88, 08003 Barcelona, Spain
Country: Spain
Phone: +34 933160817
Fax:
Line Designation: pfu


GENOMIC FEATURES ORIGINATING FROM THIS LABNo data available


STATEMENT OF RESEARCH INTERESTS
Neurogenesis and patterning mechanisms in the inner ear, sensory gene cis- regulatory elements.


LAB MEMBERS
Moreno, Alex Robert Post-Doc Radosevic, Marija Graduate Student Linares, Marta Technical Staff
Sas, Miquel Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Hoijman, E., Fargas, L., Blader, P., Alsina, B. (2017) Pioneer neurog1 expressing cells ingress into the otic epithelium and instruct neuronal specification. eLIFE. 6
Alsina, B., Whitfield, T.T. (2016) Sculpting the labyrinth: morphogenesis of the developing inner ear. Seminars in Cell & Developmental Biology.
Rubbini, D., Robert-Moreno, À., Hoijman, E., Alsina, B. (2015) Retinoic Acid Signaling Mediates Hair Cell Regeneration by Repressing p27kip and sox2 in Supporting Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:15752-66
Hoijman, E., Rubbini, D., Colombelli, J., Alsina, B. (2015) Mitotic cell rounding and epithelial thinning regulate lumen growth and shape. Nature communications. 6:7355
Iturbide, A., Pascual-Reguant, L., Fargas, L., Cebrià, J.P., Alsina, B., García de Herreros, A., Peiró, S. (2015) LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation. Molecular Cell. 58(5):755-66
Radosevic, M., Fargas, L., Alsina, B. (2014) The Role of her4 in Inner Ear Development and Its Relationship with Proneural Genes and Notch Signalling. PLoS One. 9:e109860
Mora, N., Almudi, I., Alsina, B., Corominas, M., and Serras, F. (2013) The Beta-amyloid protein precursor like (Appl) is a Ras1/MAPK regulated gene required for axonal targeting in Drosophila photoreceptor neurons. The Journal of cell biology. 126(1):53-59
Radosevic, M., Robert-Moreno, A., Coolen, M., Bally-Cuif, L., and Alsina, B. (2011) Her9 represses neurogenic fate downstream of Tbx1 and retinoic acid signaling in the inner ear. Development (Cambridge, England). 138(3):397-408
Robert-Moreno, A., Naranjo, S., de la Calle-Mustienes, E., Gomez-Skarmeta, J.L., and Alsina, B. (2010) Characterization of new otic enhancers of the pou3f4 gene reveal distinct signaling pathway regulation and spatio-temporal patterns. PLoS One. 5(12):e15907
Naranjo, S., Voesenek, K., de la Calle-Mustienes, E., Robert-Moreno, A., Kokotas, H., Grigoriadou, M., Economides, J., Van Camp, G., Hilgert, N., Moreno, F., Alsina, B., Petersen, M.B., Kremer, H., and Gómez-Skarmeta, J.L. (2010) Multiple enhancers located in a 1-Mb region upstream of POU3F4 promote expression during inner ear development and may be required for hearing. Human genetics. 128(4):411-419
Abello, G., and Alsina, B. (2007) Establishment of a proneural field in the inner ear. The International journal of developmental biology. 51(6-7):483-493
Aragon, F., Vazquez-Echeverria, C., Ulloa, E., Reber, M., Cereghini, S., Alsina, B., Giraldez, F., and Pujades, C. (2005) vHnf1 regulates specification of caudal rhombomere identity in the chick hindbrain. Developmental dynamics : an official publication of the American Association of Anatomists. 234(3):567-576