ZFIN ID: ZDB-LAB-101214-2
Bryson-Richardson Lab
PI/Director: Bryson-Richardson, Robert
Contact Person: Bryson-Richardson, Robert
Email: robert.bryson-richardson@monash.edu
URL: http://www.myopathyresearch.org
Address: School of Biological Sciences Monash University Victoria 3800 Australia
Country: Australia
Phone: (+61) 3 99024629
Fax:
Line Designation: mo


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 6 genomic features


STATEMENT OF RESEARCH INTERESTS
The Bryson-Richardson lab is interested in understanding the process of cardiac and skeletal muscle formation and the diseases that result from disruption of this process. We utilise the advantages of the zebrafish model system to understand the mechanism by which the complex architecture of the muscle is patterned and how disruption of these processes result in disease.

The research of the lab is focused on three main areas:
Myopathy research - genetic causes, pathological mechanisms, and potential therapies for muscle disease

Cardiac development - the role of blood flow in heart development and congenital heart disease

3D and 4D imaging - developing research tools and resources for the research community


LAB MEMBERS
Sztal, Tamar Esther Post-Doc Ruparelia, Avnika Graduate Student Vaz, Raquel Graduate Student
Zhao, Mo Graduate Student Johnston, Caitlin Research Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Vaz, R., Lindstrand, A. (2017) ankdd1b expression pattern in early stages of zebrafish development. ZFIN Direct Data Submission.
O'Grady, G.L., Best, H.A., Sztal, T.E., Schartner, V., Sanjuan-Vazquez, M., Donkervoort, S., Abath Neto, O., Sutton, R.B., Ilkovski, B., Romero, N.B., Stojkovic, T., Dastgir, J., Waddell, L.B., Boland, A., Hu, Y., Williams, C., Ruparelia, A.A., Maisonobe, T., Peduto, A.J., Reddel, S.W., Lek, M., Tukiainen, T., Cummings, B.B., Joshi, H., Nectoux, J., Brammah, S., Deleuze, J.F., Ing, V.O., Ramm, G., Ardicli, D., Nowak, K.J., Talim, B., Topaloglu, H., Laing, N.G., North, K.N., MacArthur, D.G., Friant, S., Clarke, N.F., Bryson-Richardson, R.J., Bönnemann, C.G., Laporte, J., Cooper, S.T. (2016) Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization. American journal of human genetics. 99(5):1086-1105
Leber, Y., Ruparelia, A.A., Kirfel, G., van der Ven, P.F., Hoffmann, B., Merkel, R., Bryson-Richardson, R.J., Fürst, D.O. (2016) Filamin C is a highly dynamic protein associated with fast repair of myofibrillar microdamage. Human Molecular Genetics. 25(13):2776-2788
Ruparelia, A.A., Oorschot, V., Ramm, G., Bryson-Richardson, R.J. (2016) FLNC myofibrillar myopathy results from impaired autophagy and protein insufficiency. Human Molecular Genetics. 25(11):2131-2142
Giousoh, A., Vaz, R., Bryson-Richardson, R.J., Whisstock, J.C., Verkade, H., Bird, P.I. (2015) Bone morphogenetic protein/retinoic acid inducible neural-specific protein (brinp) expression during Danio rerio development. Gene Expression Patterns. 18(1-2):37-43
Sztal, T.E., Zhao, M., Williams, C., Oorschot, V., Parslow, A.C., Giousoh, A., Yuen, M., Hall, T.E., Costin, A., Ramm, G., Bird, P.I., Busch-Nentwich, E.M., Stemple, D.L., Currie, P.D., Cooper, S.T., Laing, N.G., Nowak, K.J., Bryson-Richardson, R.J. (2015) Zebrafish models for nemaline myopathy reveal a spectrum of nemaline bodies contributing to reduced muscle function. Acta Neuropathologica. 130(3):389-406
Pelliccia, D., Vaz, R., Svalbe, I., Morgan, K.S., Marathe, S., Xiao, X., Assoufid, L., Anderson, R.A., Topczewski, J., Bryson-Richardson, R.J. (2015) Comparison of different numerical treatments for x-ray phase tomography of soft tissue from differential phase projections. Physics in Medicine and Biology. 60:3065-3080
Ruparelia, A.A., Oorschot, V., Vaz, R., Ramm, G., Bryson-Richardson, R.J. (2014) Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency. Acta Neuropathologica. 128(6):821-33
Oorschot, V.M., Sztal, T.E., Bryson-Richardson, R.J., Ramm, G. (2014) Immuno correlative light and electron microscopy on tokuyasu cryosections. Methods in cell biology. 124:241-58
Jamison, R.A., Samarage, C.R., Bryson-Richardson, R.J., and Fouras, A. (2013) In Vivo Wall Shear Measurements within the Developing Zebrafish Heart. PLoS One. 8(10):e75722
Ravenscroft, G., Miyatake, S., Lehtokari, V.L., Todd, E.J., Vornanen, P., Yau, K.S., Hayashi, Y.K., Miyake, N., Tsurusaki, Y., Doi, H., Saitsu, H., Osaka, H., Yamashita, S., Ohya, T., Sakamoto, Y., Koshimizu, E., Imamura, S., Yamashita, M., Ogata, K., Shiina, M., Bryson-Richardson, R.J., Vaz, R., Ceyhan, O., Brownstein, C.A., Swanson, L.C., Monnot, S., Romero, N.B., Amthor, H., Kresoje, N., Sivadorai, P., Kiraly-Borri, C., Haliloglu, G., Talim, B., Orhan, D., Kale, G., Charles, A.K., Fabian, V.A., Davis, M.R., Lammens, M., Sewry, C.A., Manzur, A., Muntoni, F., Clarke, N.F., North, K.N., Bertini, E., Nevo, Y., Willichowski, E., Silberg, I.E., Topaloglu, H., Beggs, A.H., Allcock, R.J., Nishino, I., Wallgren-Pettersson, C., Matsumoto, N., and Laing, N.G. (2013) Mutations in KLHL40 Are a Frequent Cause of Severe Autosomal-Recessive Nemaline Myopathy. American journal of human genetics. 93(1):6-18
Sztal, T.E., Sonntag, C., Hall, T.E., and Currie, P.D. (2012) Epistatic dissection of laminin-receptor interactions in dystrophic zebrafish muscle. Hum. Mol. Genet.. 21(21):4718-4731
Nguyen-Chi, M.E., Bryson-Richardson, R., Sonntag, C., Hall, T.E., Gibson, A., Sztal, T., Chua, W., Schilling, T.F., and Currie, P.D. (2012) Morphogenesis and Cell Fate Determination within the Adaxial Cell Equivalence Group of the Zebrafish Myotome. PLoS Genetics. 8(10):e1003014
Ruparelia, A.A., Zhao, M., Currie, P.D., and Bryson-Richardson, R.J. (2012) Characterization and Investigation of zebrafish models of Filamin related myofibrillar myopathy. Hum. Mol. Genet.. 21(18):4073-4083
Goldshmit, Y., Matteo, R., Sztal, T., Ellett, F., Frisca, F., Moreno, K., Crombie, D., Lieschke, G.J., Currie, P.D., Sabbadini, R.A., and Pebay, A. (2012) Blockage of Lysophosphatidic Acid Signaling Improves Spinal Cord Injury Outcomes. The American journal of pathology. 181(3):978-992
Berger, J., Sztal, T., and Currie, P.D. (2012) Quantification of birefringence readily measures the level of muscle damage in zebrafish. Biochemical and Biophysical Research Communications. 423(4):785-788
Goldshmit, Y., Sztal, T.E., Jusuf, P.R., Hall, T.E., Nguyen-Chi, M., and Currie, P.D. (2012) Fgf-dependent glial cell bridges facilitate spinal cord regeneration in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(22):7477-7492
Jamison, R.A., Fouras, A., and Bryson-Richardson, R.J. (2012) Cardiac-phase filtering in intracardiac particle image velocimetry. Journal of Biomedical Optics. 17(3):036007
Tao, S., Witte, M., Bryson-Richardson, R.J., Currie, P.D., Hogan, B.M., and Schulte-Merker, S. (2011) Zebrafish prox1b Mutants Develop a Lymphatic Vasculature, and prox1b Does Not Specifically Mark Lymphatic Endothelial Cells. PLoS One. 6(12):e28934
Sztal, T., Berger, S., Currie, P.D., and Hall, T.E. (2011) Characterization of the laminin gene family and evolution in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 240(2):422-431
Jacoby, A.S., Busch-Nentwich, E., Bryson-Richardson, R.J., Hall, T.E., Berger, J., Berger, S., Sonntag, C., Sachs, C., Geisler, R., Stemple, D.L., and Currie, P.D. (2009) The zebrafish dystrophic mutant softy maintains muscle fibre viability despite basement membrane rupture and muscle detachment. Development (Cambridge, England). 136(19):3367-3376
Bryson-Richardson, R.J., Berger, S., Schilling, T.F., Hall, T.E., Cole, N.J., Gibson, A.J., Sharpe, J., and Currie, P.D. (2007) FishNet: an online database of zebrafish anatomy. BMC Biology. 5(1):34
Hall, T.E., Bryson-Richardson, R.J., Berger, S., Jacoby, A.S., Cole, N.J., Hollway, G.E., Berger, J., and Currie, P.D. (2007) The zebrafish candyfloss mutant implicates extracellular matrix adhesion failure in laminin {alpha}2-deficient congenital muscular dystrophy. Proc. Natl. Acad. Sci. USA. 104(17):7092-7097
Nousch, M., Reed, V., Bryson-Richardson, R.J., Currie, P.D., and Preiss, T. (2007) The eIF4G-homolog p97 can activate translation independent of caspase cleavage. RNA (New York, N.Y.). 13(3):374-384
Hollway, G.E., Bryson-Richardson, R.J., Berger, S., Cole, N.J., Hall, T.E., and Currie, P.D. (2007) Whole-somite rotation generates muscle progenitor cell compartments in the developing zebrafish embryo. Developmental Cell. 12(2):207-219
Bryson-Richardson, R.J., Daggett, D.F., Cortes, F., Neyt, C., Keenan, D.G., and Currie, P.D. (2005) Myosin heavy chain expression in zebrafish and slow muscle composition. Developmental dynamics : an official publication of the American Association of Anatomists. 233(3):1018-1022
Bryson-Richardson, RJ., and Currie, P.D. (2004) Optical projection tomography for spatio-temporal analysis in the zebrafish. The Zebrafish: Cellular and Developmental Biology,2nd Ed. Methods Cell Biol.. 76:37-50
Haines, L., Neyt, C., Gautier, P., Keenan, D.G., Bryson-Richardson, R.J., Hollway, G.E., Cole, N.J., Currie, P.D. (2004) Met and Hgf signaling controls hypaxial muscle and lateral line development in the zebrafish. Development (Cambridge, England). 131(19):4857-4869
Daggett, D.F., Boyd, C.A,. Gautier, P., Bryson-Richardson, R.J., Thisse, C., Thisse, B., Amacher, S.L., and Currie, P.D. (2004) Developmentally restricted actin-regulatory molecules control morphogenetic cell movements in the zebrafish gastrula. Current biology : CB. 14(18):632-638
Bassett, D.I., Bryson-Richardson, R.J., Daggett, D.F., Gautier, P., Kennan, D.G., and Currie, P.D. (2003) Dystrophin is required for the formation of stable muscle attachments in the zebrafish embryo. Development (Cambridge, England). 130(23):5851-5860
Cortés, F., Daggett, D., Bryson-Richardson, R.J., Neyt, C., Maule, J., Gautier, P., Hollway, G.E., Keenan, D., and Currie, P.D. (2003) Cadherin-mediated differential cell adhesion controls slow muscle cell migration in the developing zebrafish myotome. Developmental Cell. 5(6):865-876
Logan, D.W., Bryson-Richardson, R.J., Taylor, M.S., Currie, P., and Jackson, I.J. (2003) Sequence characterization of teleost fish melanocortin receptors. Annals of the New York Academy of Sciences. 994:319-330
Logan, D.W., Bryson-Richardson, R.J., Pagan, K.E., Taylor, M.S., Currie, P.D., and Jackson, I.J. (2003) The structure and evolution of the melanocortin and MCH receptors in fish and mammals. Genomics. 81(2):184-191
Logan, D.W., Bryson-Richardson, R.J., Taylor, M.S., and Jackson, I.J. (2002) Characterization of melanocortin receptor genes in teleost fish. Pigm. Cell Res.. 15(9):41