ZFIN ID: ZDB-LAB-100614-1
Sakaguchi Lab
PI/Director: Sakaguchi, Takuya
Contact Person: Sakaguchi, Takuya
Email: sakagut2@ccf.org
URL:
Address: 9500 Euclid Ave. NE30 Cleveland, OH 44195
Country: United States
Phone: 216-445-9280
Fax: 216-636-5454
Line Designation: lri


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 4 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Nussbaum, Justin M. Post-Doc Schaub, Madeline Research Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
DeRossi, C., Bambino, K., Morrison, J., Sakarin, I., Villacorta-Martin, C., Zhang, C., Ellis, J.L., Fiel, M.I., Ybanez, M., Lee, Y.A., Huang, K.L., Yin, C., Sakaguchi, T.F., Friedman, S.L., Villanueva, A., Chu, J. (2019) Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans. Hepatology (Baltimore, Md.). 70(6):2107-2122
Posner, M., Murray, K.L., McDonald, M.S., Eighinger, H., Andrew, B., Drossman, A., Haley, Z., Nussbaum, J., David, L.L., Lampi, K.J. (2017) The zebrafish as a model system for analyzing mammalian and native α-crystallin promoter function.. PeerJ. 5:e4093
Dimri, M., Bilogan, C., Pierce, L.X., Naegele, G., Vasanji, A., Gibson, I., McClendon, A., Tae, K., Sakaguchi, T.F. (2017) Three-dimensional structural analysis reveals a Cdk5-mediated kinase cascade regulating hepatic biliary network branching in zebrafish. Development (Cambridge, England). 144:2595-2605
Davuluri, G., Song, P., Liu, Z., Wald, D., Sakaguchi, T.F., Green, M.R., Devireddy, L. (2016) Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy. Proceedings of the National Academy of Sciences of the United States of America. 113(11):E1460-9
Posner, M., Skiba, J., Brown, M., Liang, J.O., Nussbaum, J., and Prior, H. (2013) Loss of the small heat shock protein alphaA-crystallin does not lead to detectable defects in early zebrafish lens development. Experimental Eye Research. 116:227-33
Nussbaum, J.M., Liu, L.J., Hasan, S.A., Schaub, M., McClendon, A., Stainier, D.Y., and Sakaguchi, T.F. (2013) Homeostatic generation of reactive oxygen species protects the zebrafish liver from steatosis. Hepatology (Baltimore, Md.). 58(4):1326-1338
Schaub, M., Nussbaum, J., Verkade, H., Ober, E.A., Stainier, D.Y., and Sakaguchi, T.F. (2012) Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. Developmental Biology. 363(1):128-137
Sakaguchi, T.F., Sadler, K.C., Crosnier, C., and Stainier, D.Y. (2008) Endothelial Signals Modulate Hepatocyte Apicobasal Polarization in Zebrafish. Current biology : CB. 18(20):1565-1571
Sakaguchi, T., Kikuchi, Y., Kuroiwa, A., Takeda, H., and Stainier, D.Y. (2006) The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish. Development (Cambridge, England). 133(20):4063-4072
Kawamura, A., Koshida, S., Hijikata, H., Sakaguchi, T., Kondoh, H., and Takada, S. (2005) Zebrafish Hairy/Enhancer of split protein links FGF signaling to cyclic gene expression in the periodic segmentation of somites. Genes & Development. 19(10):1156-1161
Takeuchi, M., Nakabayashi, J., Sakaguchi, T., Yamamoto, T.S., Takahashi, H., Takeda, H., and Ueno, N. (2003) The prickle-related gene in vertebrates is essential for gastrulation cell movements. Current biology : CB. 13(8):674-679
Sakaguchi, T., Mizuno, T., and Takeda, H. (2002) Formation and patterning roles of the yolk syncytial layer. Results and problems in cell differentiation. 40:1-14
Sakaguchi, T., Kuroiwa, A., and Takeda, H. (2001) A novel sox gene, 226D7, acts downstream of Nodal signaling to specify endoderm precursors in zebrafish. Mechanisms of Development. 107(1-2):25-38
Sakaguchi, T., Kuroiwa, A., and Takeda, H. (2001) Expression of zebrafish btg-b, an anti-proliferative cofactor, during early embryogenesis. Mechanisms of Development. 104(1-2):113-115