ZFIN ID: ZDB-LAB-080804-1
Bagnat Lab
PI/Director: Bagnat, Michel
Contact Person: Bagnat, Michel
Email: m.bagnat@cellbio.duke.edu
URL: http://www.cellbio.duke.edu/Faculty/Research/Bagnat.html
Address: 333B Nanaline Duke Bldg., Box 3709, Duke University Medical Center, Durham, NC 27710
Country: United States
Phone: 919-681-9268
Fax: 919-684-5481
Line Designation: pd


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show first 50 of 65 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Levic, D.S., Ryan, S., Marjoram, L., Honeycutt, J., Bagwell, J., Bagnat, M. (2020) Distinct roles for luminal acidification in apical protein sorting and trafficking in zebrafish. The Journal of cell biology. 219(4):
Bagwell, J., Norman, J., Ellis, K.L., Peskin, B., Hwang, J., Ge, X., Nguyen, S., McMenamin, S.K., Stainier, D.Y., Bagnat, M. (2020) Notochord vacuoles absorb compressive bone growth during zebrafish spine formation. eLIFE. 9:
Ye, L., Mueller, O., Bagwell, J., Bagnat, M., Liddle, R.A., Rawls, J.F. (2019) High fat diet induces microbiota-dependent silencing of enteroendocrine cells. eLIFE. 8:
Park, J., Levic, D.S., Sumigray, K.D., Bagwell, J., Eroglu, O., Block, C.L., Eroglu, C., Barry, R., Lickwar, C.R., Rawls, J.F., Watts, S.A., Lechler, T., Bagnat, M. (2019) Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut. Developmental Cell. 51(1):7-20.e6
Norman, J., Sorrell, E.L., Hu, Y., Siripurapu, V., Garcia, J., Bagwell, J., Charbonneau, P., Lubkin, S.R., Bagnat, M. (2018) Tissue self-organization underlies morphogenesis of the notochord. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 373(1759):
Wopat, S., Bagwell, J., Sumigray, K.D., Dickson, A.L., Huitema, L.F.A., Poss, K.D., Schulte-Merker, S., Bagnat, M. (2018) Spine Patterning Is Guided by Segmentation of the Notochord Sheath. Cell Reports. 22:2026-2038
Goudarzi, M., Tarbashevich, K., Mildner, K., Begemann, I., Garcia, J., Paksa, A., Reichman-Fried, M., Mahabaleshwar, H., Blaser, H., Hartwig, J., Zeuschner, D., Galic, M., Bagnat, M., Betz, T., Raz, E. (2017) Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations. Developmental Cell. 43(5):577-587.e5
van der Vaart, M., Svoboda, O., Weijts, B.G., Espín-Palazón, R., Sapp, V., Pietri, T., Bagnat, M., Muotri, A.R., Traver, D. (2017) Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation.. Disease models & mechanisms. 10(12):1439-1451
Garcia, J., Bagwell, J., Njaine, B., Norman, J., Levic, D.S., Wopat, S., Miller, S.E., Liu, X., Locasale, J.W., Stainier, D.Y.R., Bagnat, M. (2017) Sheath Cell Invasion and Trans-differentiation Repair Mechanical Damage Caused by Loss of Caveolae in the Zebrafish Notochord. Current biology : CB. 27(13):1982-1989.e3
Smith, C.J., Wheeler, M.A., Marjoram, L., Bagnat, M., Deppmann, C.D., Kucenas, S. (2017) TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone. PLoS Genetics. 13:e1006712
Cao, J., Navis, A., Cox, B.D., Dickson, A.L., Gemberling, M., Karra, R., Bagnat, M., Poss, K.D. (2016) Single epicardial cell transcriptome sequencing identifies Caveolin-1 as an essential factor in zebrafish heart regeneration. Development (Cambridge, England). 143(2):232-43
Navis, A., Bagnat, M. (2015) Loss of cftr function leads to pancreatic destruction in larval zebrafish. Developmental Biology. 399(2):237-48
Marjoram, L., Alvers, A., Deerhake, M.E., Bagwell, J., Mankiewicz, J., Cocchiaro, J.L., Beerman, R.W., Willer, J., Sumigray, K.D., Katsanis, N., Tobin, D.M., Rawls, J.F., Goll, M.G., Bagnat, M. (2015) Epigenetic control of intestinal barrier function and inflammation in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 112(9):2770-5
Rodríguez-Fraticelli, A.E., Bagwell, J., Bosch-Fortea, M., Boncompain, G., Reglero-Real, N., García-León, M.J., Andrés, G., Toribio, M.L., Alonso, M.A., Millán, J., Perez, F., Bagnat, M., Martín-Belmonte, F. (2015) Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs. Nature cell biology. 17(3):241-50
Alvers, A.L., Ryan, S., Scherz, P.J., Huisken, J., and Bagnat, M. (2014) Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling. Development (Cambridge, England). 141(5):1110-1119
Gray, R.S., Wilm, T.P., Smith, J., Bagnat, M., Dale, R.M., Topczewski, J., Johnson, S.L., and Solnica-Krezel, L. (2014) Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations. Developmental Biology. 386(1):72-85
Ryan, S., Willer, J., Marjoram, L., Bagwell, J., Mankiewicz, J., Leshchiner, I., Goessling, W., Bagnat, M., and Katsanis, N. (2013) Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish. Development (Cambridge, England). 140(21):4445-4451
Ellis, K., Hoffman, B.D., and Bagnat, M. (2013) The vacuole within: How cellular organization dictates notochord function. Bioarchitecture. 3(3):64-68
Navis, A., Marjoram, L., and Bagnat, M. (2013) Cftr controls lumen expansion and function of Kupffer's vesicle in zebrafish. Development (Cambridge, England). 140(8):1703-1712
Ellis, K., Bagwell, J., and Bagnat, M. (2013) Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis. The Journal of cell biology. 200(5):667-679
Cheung, I.D., Bagnat, M., Ma, T.P., Datta, A., Evason, K., Moore, J.C., Lawson, N.D., Mostov, K.E., Moens, C.B., and Stainier, D.Y. (2012) Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. Developmental Biology. 361(1):68-78
Kanther, M., Sun, X., Mühlbauer, M., Mackey, L.C., Flynn, E.J., Bagnat, M., Jobin, C., and Rawls, J.F. (2011) Microbial colonization induces dynamic temporal and spatial patterns of NF-kappaB activation in the zebrafish digestive tract. Gastroenterology. 141(1):197-207
Bagnat, M., Navis, A., Herbstreith, S., Brand-Arzamendi, K., Curado, S., Gabriel, S., Mostov, K., Huisken, J., and Stainier, D.Y. (2010) Cse1l Is a Negative Regulator of CFTR-Dependent Fluid Secretion. Current biology : CB. 20(20):1840-1845
Bagnat, M., Cheung, I.D., Mostov, K.E., and Stainier, D.Y. (2007) Genetic control of single lumen formation in the zebrafish gut. Nature cell biology. 9(8):954-960