ZFIN ID: ZDB-LAB-070910-1
Englert Lab
PI/Director: Englert, Christoph
Contact Person: Perner, Birgit
Email: perner@fli-leibniz.de
URL: http://www.fli-leibniz.de/groups/englert_en.php
Address: Molecular Genetics Leibniz Institute for Age Research - Fritz Lipmann Institute (FLI) Beutenbergstrasse 11 07745 Jena Germany
Country: Germany
Phone: +49 3641 656041
Fax: +49 3641 656040
Line Designation: li


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 20 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Bollig, Frank Post-Doc Perner, Birgit Post-Doc Reichardt, Claudia Graduate Student


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Sanz-Morejón, A., García-Redondo, A.B., Reuter, H., Marques, I.J., Bates, T., Galardi-Castilla, M., Große, A., Manig, S., Langa, X., Ernst, A., Piragyte, I., Botos, M.A., González-Rosa, J.M., Ruiz-Ortega, M., Briones, A.M., Salaices, M., Englert, C., Mercader, N. (2019) Wilms Tumor 1b Expression Defines a Pro-regenerative Macrophage Subtype and Is Required for Organ Regeneration in the Zebrafish. Cell Reports. 28:1296-1306.e6
Große, A., Perner, B., Naumann, U., Englert, C. (2019) Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis. Developmental dynamics : an official publication of the American Association of Anatomists. 248(9):866-881
Kindermann, B., Valkova, C., Krämer, A., Perner, B., Engelmann, C., Behrendt, L., Kritsch, D., Jungnickel, B., Kehlenbach, R.H., Oswald, F., Englert, C., Kaether, C. (2019) The nuclear pore proteins Nup88/214 and T-ALL-associated NUP214 fusion proteins regulate Notch signaling. The Journal of biological chemistry. 294(31):11741-11750
Lopez-Baez, J.C., Simpson, D.J., LLeras Forero, L., Zeng, Z., Brunsdon, H., Salzano, A., Brombin, A., Wyatt, C., Rybski, W., Huitema, L.F.A., Dale, R.M., Kawakami, K., Englert, C., Chandra, T., Schulte-Merker, S., Hastie, N.D., Patton, E.E. (2018) Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair.. eLIFE. 7
Aramillo Irizar, P., Schäuble, S., Esser, D., Groth, M., Frahm, C., Priebe, S., Baumgart, M., Hartmann, N., Marthandan, S., Menzel, U., Müller, J., Schmidt, S., Ast, V., Caliebe, A., König, R., Krawczak, M., Ristow, M., Schuster, S., Cellerino, A., Diekmann, S., Englert, C., Hemmerich, P., Sühnel, J., Guthke, R., Witte, O.W., Platzer, M., Ruppin, E., Kaleta, C. (2018) Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly. Nature communications. 9:327
Perner, B., Schnerwitzki, D., Graf, M., Englert, C. (2016) Analysis of Zebrafish Kidney Development with Time-lapse Imaging Using a Dissecting Microscope Equipped for Optical Sectioning. Journal of visualized experiments : JoVE. (110):e53921
Baumgart, M., Priebe, S., Groth, M., Hartmann, N., Menzel, U., Pandolfini, L., Koch, P., Felder, M., Ristow, M., Englert, C., Guthke, R., Platzer, M., Cellerino, A. (2016) Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan. Cell systems. 2:122-132
Bates, T.J., Naumann, U., Englert, C. (2016) Fluorescence-Activated Cell Sorting (FACS) Protocol for Podocyte Isolation in Adult Zebrafish. Methods in molecular biology (Clifton, N.J.). 1467:133-6
Perner, B., Bates, T.J., Naumann, U., Englert, C. (2016) Function and Regulation of the Wilms' Tumor Suppressor 1 (WT1) Gene in Fish. Methods in molecular biology (Clifton, N.J.). 1467:119-28
Perner, B., Englert, C. (2016) Immunofluorescence Staining of Wt1 on Sections of Zebrafish Embryos and Larvae. Methods in molecular biology (Clifton, N.J.). 1467:129-32
Mansfeld, J., Urban, N., Priebe, S., Groth, M., Frahm, C., Hartmann, N., Gebauer, J., Ravichandran, M., Dommaschk, A., Schmeisser, S., Kuhlow, D., Monajembashi, S., Bremer-Streck, S., Hemmerich, P., Kiehntopf, M., Zamboni, N., Englert, C., Guthke, R., Kaleta, C., Platzer, M., Sühnel, J., Witte, O.W., Zarse, K., Ristow, M. (2015) Branched-chain amino acid catabolism is a conserved regulator of physiological ageing. Nature communications. 6:10043
Dong, L., Pietsch, S., Tan, Z., Perner, B., Sierig, R., Kruspe, D., Groth, M., Witzgall, R., Gröne, H., Platzer, M., Englert, C. (2015) Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance. Journal of the American Society of Nephrology : JASN. 26(9):2118-28
Schnerwitzki, D., Perner, B., Hoppe, B., Pietsch, S., Mehringer, R., Hänel, F., Englert, C. (2014) Alternative splicing of Wilms tumor suppressor 1 (Wt1) exon 4 results in protein isoforms with different functions. Developmental Biology. 393(1):24-32
Burghardt, T., Kastner, J., Suleiman, H., Rivera-Milla, E., Stepanova, N., Lottaz, C., Kubitza, M., Böger, C.A., Schmidt, S., Gorski, M., de Vries, U., Schmidt, H., Hertting, I., Kopp, J., Rascle, A., Moser, M., Heid, I.M., Warth, R., Spang, R., Wegener, J., Mierke, C.T., Englert, C., and Witzgall, R. (2013) LMX1B is Essential for the Maintenance of Differentiated Podocytes in Adult Kidneys. Journal of the American Society of Nephrology : JASN. 24(11):1830-48
Krämer, A., Mentrup, T., Kleizen, B., Rivera-Milla, E., Reichenbach, D., Enzensperger, C., Nohl, R., Täuscher, E., Görls, H., Ploubidou, A., Englert, C., Werz, O., Arndt, H.D., and Kaether, C. (2013) Small molecules intercept Notch signaling and the early secretory pathway. Nature Chemical Biology. 9(11):731-738
Kirsch, T., Kaufeld, J., Korstanje, R., Hentschel, D.M., Staggs, L., Bollig, F., Beese, M., Schroder, P., Boehme, L., Haller, H., and Schiffer, M. (2013) Knockdown of the Hypertension-Associated Gene NOSTRIN Alters Glomerular Barrier Function in Zebrafish (Danio rerio). Hypertension (Dallas, Tex. : 1979). 62(4):726-30
Petzold, A., Reichwald, K., Groth, M., Taudien, S., Hartmann, N., Priebe, S., Shagin, D., Englert, C., and Platzer, M. (2013) The transcript catalogue of the short-lived fish Nothobranchius furzeri provides insights into age-dependent changes of mRNA levels. BMC Genomics. 14:185
Schuler, S., Hauptmann, J., Perner, B., Kessels, M.M., Englert, C., and Qualmann, B. (2013) Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2 domain-based actin nucleator Cobl. Journal of Cell Science. 126(1):196-208
Stengel, R., Rivera-Milla, E., Sahoo, N., Ebert, C., Bollig, F., Heinemann, S.H., Schonherr, R., and Englert, C. (2012) Kcnh1 voltage-gated potassium channels are essential for early zebrafish development. The Journal of biological chemistry. 287(42):35565-35575
Müller, T., Rumpel, E., Hradetzky, S., Bollig, F., Wegner, H., Blumenthal, A., Greinacher, A., Endlich, K., and Endlich, N. (2011) Non-muscle myosin IIA is required for the development of the zebrafish glomerulus. Kidney International. 80(10):1055-63
Diep, C.Q., Ma, D., Deo, R.C., Holm, T.M., Naylor, R.W., Arora, N., Wingert, R.A., Bollig, F., Djordjevic, G., Lichman, B., Zhu, H., Ikenaga, T., Ono, F., Englert, C., Cowan, C.A., Hukriede, N.A., Handin, R.I., and Davidson, A.J. (2011) Identification of adult nephron progenitors capable of kidney regeneration in zebrafish. Nature. 470(7332):95-100
Landgraf, K., Bollig, F., Trowe, M.O., Besenbeck, B., Ebert, C., Kruspe, D., Kispert, A., Hänel, F., and Englert, C. (2010) Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development. Molecular and cellular biology. 30(24):5764-5775
Zhou, W., Boucher, R.C., Bollig, F., Englert, C., and Hildebrandt, F. (2010) Characterization of Mesonephric Development and Regeneration Using Transgenic Zebrafish. American journal of physiology. Renal physiology. 299(5):F1040-F1047
Ashworth, S., Teng, B., Kaufeld, J., Miller, E., Tossidou, I., Englert, C., Bollig, F., Staggs, L., Roberts, I.S., Park, J.K., Haller, H., and Schiffer, M. (2010) Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans. PLoS One. 5(9):e12626
Miloslavina, A., Ebert, C., Tietze, D., Ohlenschläger, O., Englert, C., Görlach, M., and Imhof, D. (2010) An unusual peptide from Conus villepinii: synthesis, solutiuon structure, and cardioactivity. Peptides. 31(7):1292-1300
Kim, M.S., Yoon, S.K., Bollig, F., Kitagaki, J., Hur, W., Whye, N.J., Wu, Y.P., Rivera, M.N., Park, J.Y., Kim, H.S., Malik, K., Bell, D.W., Englert, C., Perantoni, A.O., and Lee, S.B. (2010) A novel Wilms Tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway. The Journal of biological chemistry. 285(19):14585-14593
Bollig, F., Perner, B., Besenbeck, B., Köthe, S., Ebert, C., Taudien, S., and Englert, C. (2009) A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros. Development (Cambridge, England). 136(17):2883-2892
Skouloudaki, K., Puetz, M., Simons, M., Courbard, J.R., Boehlke, C., Hartleben, B., Engel, C., Moeller, M.J., Englert, C., Bollig, F., Schäfer, T., Ramachandran, H., Mlodzik, M., Huber, T.B., Kuehn, E.W., Kim, E., Kramer-Zucker, A., and Walz, G. (2009) Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. Proceedings of the National Academy of Sciences of the United States of America. 106(21):8579-8584
Reichwald, K., Lauber, C., Nanda, I., Kirschner, J., Hartmann, N., Schories, S., Gausmann, U., Taudien, S., Schilhabel, M.B., Szafranski, K., Glockner, G., Schmid, M., Cellerino, A., Schartl, M., Englert, C., and Platzer, M. (2009) High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research. Genome biology. 10(2):R16
Perner, B., Englert, C., and Bollig, F. (2007) The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros. Developmental Biology. 309(1):87-96
Bollig, F., Mehringer, R., Perner, B., Hartung, C., Schafer, M., Schartl, M., Volff, J.N., Winkler, C., and Englert, C. (2006) Identification and comparative expression analysis of a second wt1 gene in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 235(2):554-561