ZFIN ID: ZDB-LAB-070315-1
McDermott Lab
PI/Director: McDermott Jr., Brian M.
Contact Person: McDermott Jr., Brian M.
Email: bmm30@case.edu
URL:
Address: Case Western Reserve University Department of Otolaryngology 1100 Euclid Ave Wearn/452 Cleveland, Ohio 44106
Country: United States
Phone: 216-844-6119
Fax:
Line Designation: cwr


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 10 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Bai, Haimeng (Steven) Graduate Student Davis, Robin Woods Graduate Student Gupta, Nilay Graduate Student
Pollock, Lana Graduate Student Sun, Shenyu (Shawn) Graduate Student Wang, Shengxuan (Kelsi) Graduate Student
Zhu, Shaoyuan (Sara) Graduate Student Zongwei, Cheng (Kevin) Graduate Student Fernando, Carol Research Staff
Ko, Bona


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Gopal, S.R., Lee, Y.T., Stepanyan, R., McDermott, B.M., Alagramam, K.N. (2019) Unconventional secretory pathway activation restores hair cell mechanotransduction in an USH3A model. Proceedings of the National Academy of Sciences of the United States of America. 116(22):11000-11009
Pollock, L.M., Xie, J., Bell, B.A., Anand-Apte, B. (2018) Retinoic acid signaling is essential for maintenance of the blood-retinal barrier. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(10):5674-5684
Chou, S.W., Chen, Z., Zhu, S., Davis, R.W., Hu, J., Liu, L., Fernando, C.A., Kindig, K., Brown, W.C., Stepanyan, R., McDermott, B.M. (2017) A molecular basis for water motion detection by the mechanosensory lateral line of zebrafish. Nature communications. 8:2234
Vargo, J.W., Walker, S.N., Gopal, S.R., Deshmukh, A.R., McDermott, B.M., Alagramam, K.N., Stepanyan, R. (2017) Inhibition of Mitochondrial Division Attenuates Cisplatin-Induced Toxicity in the Neuromast Hair Cells. Frontiers in Cellular Neuroscience. 11:393
Chen, Z., Chou, S.W., McDermott, B.M. (2017) Ribeye protein is intrinsically dynamic but is stabilized in the context of the ribbon synapse. The Journal of physiology. 596(3):409-421
Pollock, L.M., Gupta, N., Chen, X., Luna, E.J., McDermott, B.M. (2016) Supervillin Is a Component of the Hair Cell's Cuticular Plate and the Head Plates of Organ of Corti Supporting Cells. PLoS One. 11:e0158349
Hwang, P., Chou, S.W., Chen, Z., McDermott, B.M. (2015) The Stereociliary Paracrystal Is a Dynamic Cytoskeletal Scaffold In Vivo. Cell Reports. 13(7):1287-94
Gopal, S.R., Chen, D.H., Chou, S.W., Zang, J., Neuhauss, S.C., Stepanyan, R., McDermott, B.M., Alagramam, K.N. (2015) Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:10188-201
Antonellis, P.J., Pollock, L.M., Chou, S.W., Hassan, A., Geng, R., Chen, X., Fuchs, E., Alagramam, K.N., Auer, M., and McDermott, B.M. (2014) ACF7 is a hair-bundle antecedent, positioned to integrate cuticular plate actin and somatic tubulin. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(1):305-312
Balow, S.A., Pierce, L.X., Zentner, G.E., Conrad, P.A., Davis, S., Sabaawy, H.E., McDermott, B.M., and Scacheri, P.C. (2013) Knockdown of fbxl10/kdm2bb rescues chd7 morphant phenotype in a zebrafish model of CHARGE syndrome. Developmental Biology. 382(1):57-69
Santos-Cortez, R.L., Lee, K., Azeem, Z., Antonellis, P.J., Pollock, L.M., Khan, S., Irfanullah, I., Andrade-Elizondo, P.B., Chiu, I., Adams, M.D., Basit, S., Smith, J.D., Nickerson, D.A., McDermott, B.M., Ahmad, W., and Leal, S.M. (2013) Mutations in KARS, Encoding Lysyl-tRNA Synthetase, Cause Autosomal-Recessive Nonsyndromic Hearing Impairment DFNB89. American journal of human genetics. 93(1):132-40
Werdich, A.A., Brzezinski, A., Jeyaraj, D., Ficker, E., Wan, X., McDermott, B.M., Sabeh, M.K., MacRae, C.A., and Rosenbaum, D.S. (2012) The zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart. Progress in Biophysics and Molecular Biology. 110(2-3):154-165
West, M.C., and McDermott, B.M. Jr. (2011) Ribeye a-mCherry fusion protein: A novel tool for labeling synaptic ribbons of the hair cell. Journal of Neuroscience Methods. 197(2):274-8
Chou, S.W., Hwang, P., Gomez, G., Fernando, C.A., West, M.C., Pollock, L.M., Lin-Jones, J., Burnside, B., and McDermott, B.M. (2011) Fascin 2b Is a Component of Stereocilia that Lengthens Actin-Based Protrusions. PLoS One. 6(4):e14807
Fernando, C.A., Conrad, P.A., Bartels, C.F., Marques, T., To, M., Balow, S.A., Nakamura, Y., and Warman, M.L. (2010) Temporal and spatial expression of CCN genes in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 239(6):1755-1767
McDermott, B.M., Asai, Y., Baucom, J.M., Jani, S.D., Castellanos, Y., Gomez, G., McClintock, J.M., and Hudspeth, A.J. (2010) Transgenic Labeling of Hair Cells in the Zebrafish Acousticolateralis System. Gene expression patterns : GEP. 10(2-3):113-118
Nakamura, Y., Cui, Y., Fernando, C., Kutz, W.E., and Warman, M.L. (2009) Normal growth and development in mice over-expressing the CCN family member WISP3. Journal of cell communication and signaling. 3(2):105-113
Prober, D.A., Zimmerman, S., Myers, B.R., McDermott, B.M. Jr, Kim, S.H., Caron, S., Rihel, J., Solnica-Krezel, L., Julius, D., Hudspeth, A.J., and Schier, A.F. (2008) Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(40):10102-10110
McDermott, B.M., Baucom, J.M., and Hudspeth, A.J. (2007) Analysis and functional evaluation of the hair-cell transcriptome. Proceedings of the National Academy of Sciences of the United States of America. 104(28):11820-11825