ZFIN ID: ZDB-LAB-050429-1
Mably Lab
PI/Director: Mably, John
Contact Person: Mably, John
Email: MABLY@CVRC.MGH.HARVARD.EDU
URL: http://www.massgeneral.org/cvrc/crvc/mably.html
Address: MGH-East 149 13th Street CVRC, M149-4100A Charlestown MA 02129 USA
Country: United States
Phone: 617-724-8729
Fax: 617-726-5806
Line Designation: chb


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 2 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Doherty, Amy Fish Facility Staff Stone, Eric Fish Facility Staff Chuang, Lesley Technical Staff
Ser, Jennifer Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Kawasaki, J., Aegerter, S., Fevurly, R.D., Mammoto, A., Mammoto, T., Sahin, M., Mably, J.D., Fishman, S.J., Chan, J. (2014) RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity. J. Clin. Invest.. 124(6):2774-84
Sah, R., Mesirca, P., Van den Boogert, M., Rosen, J., Mably, J., Mangoni, M.E., and Clapham, D.E. (2013) Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity. Proceedings of the National Academy of Sciences of the United States of America. 110(3):E3037-E3046
Rosen, J.N., Sogah, V.M., Ye, L.Y., and Mably, J.D. (2013) Ccm2-like is required for cardiovascular development as a novel component of the Heg-CCM pathway. Developmental Biology. 376(1):74-85
Maragh, S., Miller, R.A., Bessling, S.L., McGaughey, D.M., Wessels, M.W., de Graaf, B., Stone, E.A., Bertoli-Avella, A.M., Gearhart, J.D., Fisher, S., and McCallion, A.S. (2011) Identification of RNA binding motif proteins essential for cardiovascular development. BMC Developmental Biology. 11(1):62
Castranova, D., Lawton, A., Lawrence, C., Baumann, D.P., Best, J., Coscolla, J., Doherty, A., Ramos, J., Hakkesteeg, J., Wang, C., Wilson, C., Malley, J., and Weinstein, B.M. (2011) The Effect of Stocking Densities on Reproductive Performance in Laboratory Zebrafish (Danio rerio). Zebrafish. 8(3):141-6
Chan, J., and Mably, J.D. (2011) Dissection of cardiovascular development and disease pathways in zebrafish. Progress in molecular biology and translational science. 100:111-153
Sogah, V.M., Serluca, F.C., Fishman, M.C., Yelon, D.L., MacRae, C.A., and Mably, J.D. (2010) Distinct troponin C isoform requirements in cardiac and skeletal muscle. Developmental dynamics : an official publication of the American Association of Anatomists. 239(11):3115-3123
Shin, J.T., Pomerantsev, E.V., Mably, J.D., and MacRae, C.A. (2010) High-resolution cardiovascular function confirms functional orthology of myocardial contractility pathways in zebrafish. Physiological Genomics. 42(2):300-309
Gauthier, J., Champagne, N., Lafrenière, R.G., Xiong, L., Spiegelman, D., Brustein, E., Lapointe, M., Peng, H., Côté, M., Noreau, A., Hamdan, F.F., Addington, A.M., Rapoport, J.L., Delisi, L.E., Krebs, M.O., Joober, R., Fathalli, F., Mouaffak, F., Haghighi, A.P., Néri, C., Dubé, M.P., Samuels, M.E., Marineau, C., Stone, E.A., Awadalla, P., Barker, P.A., Carbonetto, S., Drapeau, P., Rouleau, G.A. and the S2D Team. (2010) De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 107(17):7863-7868
Milan, D.J., Kim, A.M., Winterfield, J.R., Jones, I.L., Pfeufer, A., Sanna, S., Arking, D.E., Amsterdam, A.H., Sabeh, K.M., Mably, J.D., Rosenbaum, D.S., Peterson, R.T., Chakravarti, A., Kääb, S., Roden, D.M., and MacRae, C.A. (2009) Drug-Sensitized Zebrafish Screen Identifies Multiple Genes, Including GINS3, as Regulators of Myocardial Repolarization. Circulation. 120(7):553-559
Rosen, J.N., Sweeney, M.F., and Mably, J.D. (2009) Microinjection of zebrafish embryos to analyze gene function. Journal of visualized experiments : JoVE. (25)
Xiong, J.W., Yu, Q., Zhang, J., and Mably, J.D. (2008) An Acyltransferase Controls the Generation of Hematopoietic and Endothelial Lineages in Zebrafish. Circulation research. 102(9):1057-1064
Mably, J.D., Chuang, L.P., Serluca, F.C., Mohideen, M.A., Chen, J.N., and Fishman, M.C. (2006) santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish. Development (Cambridge, England). 133(16):3139-3146
Kashuk, C.S., Stone, E.A., Grice, E.A., Portnoy, M.E., Green, E.D., Sidow, A., Chakravarti, A., and McCallion, A.S. (2005) Phenotype-genotype correlation in Hirschsprung disease is illuminated by comparative analysis of the RET protein sequence. Proceedings of the National Academy of Sciences of the United States of America. 102(25):8949-8954
Mably, J.D., Mohideen, M.A.P.K., Burns, C.G., Chen, J.-N., and Fishman, M.C. (2003) heart of glass regulates the concentric growth of the heart in zebrafish. Current biology : CB. 13(24):2138-2147
Peterson, R.T., Mably, J.D., Chen, J.-N., and Fishman, M.C. (2001) Convergence of distinct pathways to heart patterning reveals by the small molecule concentramide and the mutation heart-and-soul. Current biology : CB. 11:1481-1491
Serluca, F.C., Sidow, A., Mably, J.D., and Fishman, MC. (2001) Partitioning of tissue expression accompanies multiple duplications of the Na+/K+ ATPase alpha subunit gene. Genome research. 11(10):1625-1631
Chan, J., Mably, J.D., Serluca, F.C., Chen, J.-N., Goldstein, N.B., Thomas, M.C., Cleary, J.A., Brennan, C., Fishman, M.C., and Roberts, T.M. (2001) Morphogenesis of prechordal plate and notochord requires intact Eph/Ephrin B signaling. Developmental Biology. 234(2):470-482
Chen, J.-N., van Bebber, F., Goldstein, A.M., Serluca, F.C., Jackson, D., Childs, S., Serbedzija, G., Warren, K.S., Mably, J.D., Lindahl, P., Mayer, A., Haffter, P., and Fishman, M.C. (2001) Genetic steps to organ laterality in zebrafish. Comparative and functional genomics. 2(2):60-68
Ton, C., Hwang, D.M., Dempsey, A.A., Tang, H.C., Yoon, J., Lim, M., Mably, J.D., Fishman, M.C., and Liew, C.C. (2000) Identification, characterization, and mapping of expressed sequence tags from an embryonic zebrafish heart cDNA library. Genome research. 10(12):1915-1927
Ton, C., Hwang, D.M., Dempsey, A.A., Cukeman, E., Francisco-Pabalan, O.L., Wei, W., Lee, S.Y., Mably, J.D., Fishman, M.C., and Liew, C.C. (2000) Identification, characterization and mapping of expressed sequence tags from zebrafish heart cDNA libraries. Circulation. 102(18):687