Research
General Information
ZIRC
ZFIN ID: ZDB-LAB-050107-1
Gamse Lab
PI/Director: Gamse, Josh
Contact Person: Gamse, Josh
Email: josh.gamse@vanderbilt.edu
URL: http://www.vanderbilt.edu/gamselab
Address: Department of Biological Sciences Vanderbilt University VU Station B, Box 35-1634 Nashville, TN 37235-1634 USA
Phone: 615-936-5574
Fax: 615-343-0651
Line Designation: vu


GENOMIC FEATURES ORIGINATING FROM THIS LAB

STATEMENT OF RESEARCH INTERESTS
Formation of left-right asymmetry in the brain, particularly in the epithalamus (pineal, parapineal, habenular nuclei)


LAB MEMBERS
Wu, Shu-Yu (Simon) Post-Doc Clanton, Joshua Graduate Student Dean, Benjamin Graduate Student
Doll, Caleb Graduate Student Khuansuwan, Sataree Graduate Student Taylor, Robert Graduate Student
Booton, Erin Technical Staff Guan, Qiang Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Lu, P.N., Lund, C., Khuansuwan, S., Schumann, A., Harney-Tolo, M., Gamse, J.T., and Liang, J.O. (2013) Failure in closure of the anterior neural tube causes left isomerization of the zebrafish epithalamus Dev. Biol.374(2):333-344.
Clanton, J.A., Hope, K.D., and Gamse, J.T. (2013) Fgf signaling governs cell fate in the zebrafish pineal complex Development140(2):323-332.
Wu, S.Y., Shin, J., Sepich, D.S., and Solnica-Krezel, L. (2012) Chemokine GPCR Signaling Inhibits beta-Catenin during Zebrafish Axis Formation PLoS Biol.10(10):e1001403.
Doll, C.A., Burkart, J.T., Hope, K.D., Halpern, M.E., and Gamse, J.T. (2011) Subnuclear development of the zebrafish habenular nuclei requires ER translocon function Dev. Biol.360(1):44-57.
de Borsetti, N.H., Dean, B.J., Bain, E.J., Clanton, J.A., Taylor, R.W., and Gamse, J.T. (2011) Light and melatonin schedule neuronal differentiation in the habenular nuclei Dev. Biol.358(1):251-61.
Taylor, R.W., Qi, J.Y., Talaga, A.K., Ma, T.P., Pan, L., Bartholomew, C.R., Klionsky, D.J., Moens, C.B., and Gamse, J.T. (2011) Asymmetric inhibition of ulk2 causes left-right differences in habenular neuropil formation J. Neurosci.31(27):9869-9878.
Clanton, J.A., Shestopalov, I., Chen, J., and Gamse, J.T. (2011) Lineage labeling of zebrafish cells with laser uncagable fluorescein dextran J. Vis. Exp.50:2672.
Taylor, R.W., Hsieh, Y.W., Gamse, J.T., and Chuang, C.F. (2010) Making a difference together: reciprocal interactions in C. elegans and zebrafish asymmetric neural development Development137(5):681-691.
Snelson, C.D., and Gamse, J.T. (2009) Building an asymmetric brain: Development of the zebrafish epithalamus Semin. Cell Dev. Biol.20(4):491-497.
Alvarez-Delfin, K., Morris, A.C., Snelson, C.D., Gamse, J.T., Gupta, T., Marlow, F.L., Mullins, M.C., Burgess, H.A., Granato, M., and Fadool, J.M. (2009) Tbx2b is required for ultraviolet photoreceptor cell specification during zebrafish retinal development Proc. Natl. Acad. Sci. USA106(6):2023-2028.
Snelson, C.D., Burkart, J.T., and Gamse, J.T. (2008) Formation of the asymmetric pineal complex in zebrafish requires two independently acting transcription factors Dev. Dyn.237(12):3538-3544.
Snelson, C.D., Santhakumar, K., Halpern, M.E., and Gamse, J.T. (2008) Tbx2b is required for the development of the parapineal organ Development135(9):1693-1702.
Kuan, Y.S., Gamse, J.T., Schreiber, A.M., and Halpern, M.E. (2007) Selective asymmetry in a conserved forebrain to midbrain projection J. Exp. Zoolog. B Mol. Dev. Evol.308(5):669-678.
Pineda, R.H., Svoboda, K.R., Wright, M.A., Taylor, A.D., Novak, A.E., Gamse, J.T., Eisen, J.S., and Ribera, A.B. (2006) Knockdown of Nav1.6a Na+ channels affects zebrafish motoneuron development Development133(19):3827-3836.
Gamse, J.T., Kuan, Y.S., Macurak, M., Brosamle, C., Thisse, B., Thisse, C., and Halpern, M.E. (2005) Directional asymmetry of the zebrafish epithalamus guides dorsoventral innervation of the midbrain target Development132(21):4869-4881.
Halpern, M.E., Liang, J.O., and Gamse, J.T. (2003) Leaning to the left: laterality in the zebrafish forebrain Trends Neurosci.26(6):308-313.
Gamse, J.T., Thisse, C., Thisse, B., and Halpern, M.E. (2003) The parapineal mediates left-right asymmetry in the zebrafish diencephalon Development130:1059-1068.
Gamse, J.T., Shen, Y.-C., Thisse, C., Thisse, B., Raymond, P.A., Halpern, M.E., and Liang, J.O. (2002) Otx5 regulates genes that show circadian expression in the zebrafish pineal complex Nat. Genet.30(1):117-121.
Grinblat, Y., Gamse, J., Patel, M., and Sive, H. (1998) Determination of the zebrafish forebrain: induction and patterning Development125:4403-4416.