ZFIN ID: ZDB-LAB-010202-1
Sagerström Lab
PI/Director: Sagerström, Charles
Contact Person: Sagerström, Charles
Email: charles.sagerstrom@cuanschutz.edu
URL:
Address: Department of Pediatrics Research 1 South; Room 12105 University of Colorado Medical School Mail Stop 8108 12801 E. 17th Avenue Aurora, CO 80045
Country: United States
Phone: 3037249760
Fax:
Line Designation: um


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 28 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Etheridge, Letitiah Research Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Stanney, W., Ladam, F., Donaldson, I.J., Parsons, T.J., Maehr, R., Bobola, N., Sagerström, C.G. (2019) Combinatorial action of NF-Y and TALE at embryonic enhancers defines distinct gene expression programs during zygotic genome activation in zebrafish. Developmental Biology. 459(2):161-180
Yildiz, O., Downes, G.B., Sagerström, C.G. (2019) Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain. Neural Development. 14:5
Ghosh, P., Maurer, J.M., Sagerström, C.G. (2018) Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish. Neural Development. 13:13
Ladam, F., Stanney, W., Donaldson, I.J., Yildiz, O., Bobola, N., Sagerström, C.G. (2018) TALE factors use two distinct functional modes to control an essential zebrafish gene expression program. eLIFE. 7
Maurer, J.M., Sagerström, C.G. (2018) A parental requirement for dual-specificity phosphatase 6 in zebrafish. BMC Developmental Biology. 18:6
Ghosh, P., Sagerström, C.G. (2018) Developing roles for Hox proteins in hindbrain gene regulatory networks. The International journal of developmental biology. 62:767-774
Zannino, D.A., Sagerström, C.G. (2015) An emerging role for prdm family genes in dorsoventral patterning of the vertebrate nervous system. Neural Development. 10:24
Amin, S., Donaldson, I.J., Zannino, D.A., Hensman, J., Rattray, M., Losa, M., Spitz, F., Ladam, F., Sagerström, C., Bobola, N. (2015) Hoxa2 selectively enhances Meis binding to change a branchial arch ground state. Developmental Cell. 32:265-77
Zannino, D.A., Downes, G.B., Sagerström, C.G. (2014) prdm12b specifies the p1 progenitor domain and reveals a role for V1 interneurons in swim movements. Developmental Biology. 390:247-60
Weicksel, S.E., Gupta, A., Zannino, D.A., Wolfe, S.A., Sagerström, C.G. (2014) Targeted germ line disruptions reveal general and species-specific roles for paralog group 1 hox genes in zebrafish. BMC Developmental Biology. 14:25
Choe, S.K., Ladam, F., and Sagerström, C.G. (2014) TALE factors poise promoters for activation by Hox proteins. Developmental Cell. 28(2):203-211
Ladam, F., Sagerström, C.G. (2014) Functional analysis of hox genes in zebrafish. Methods in molecular biology (Clifton, N.J.). 1196:133-44
Ladam, F., Sagerström, C.G. (2014) Hox regulation of transcription: more complex(es). Developmental dynamics : an official publication of the American Association of Anatomists. 243:4-15
Weicksel, S.E., Xu, J., and Sagerström, C.G. (2013) Dynamic Nucleosome Organization at hox Promoters during Zebrafish Embryogenesis. PLoS One. 8(5):e63175
Choe, S.K., Nakamura, M., Ladam, F., Etheridge, L., and Sagerström, C.G. (2012) A Gal4/UAS system for conditional transgene expression in rhombomere 4 of the zebrafish hindbrain. Developmental dynamics : an official publication of the American Association of Anatomists. 241(6):1125-1132
Zannino, D.A., Sagerström, C.C., and Appel, B. (2012) Olig2-expressing hindbrain cells are required for migrating facial motor neurons. Developmental dynamics : an official publication of the American Association of Anatomists. 241(2):315-326
Choe, S.K., Zhang, X., Hirsch, N., Straubhaar, J., and Sagerström, C.G. (2011) A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center. Developmental Biology. 358(2):356-67
Mallappa, C., Nasipak, B.T., Etheridge, L., Androphy, E.J., Jones, S.N., Sagerström, C.G., Ohkawa, Y., and Imbalzano, A.N. (2010) Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function. Molecular and cellular biology. 30(13):3176-3186
Alexa, K., Choe, S.K., Hirsch, N., Etheridge, L., Laver, E., and Sagerström, C.G. (2009) Maternal and zygotic aldh1a2 activity is required for pancreas development in zebrafish. PLoS One. 4(12):e8261
Choe, S.K., Lu, P., Nakamura, M., Lee, J., and Sagerström, C.G. (2009) Meis cofactors control HDAC and CBP accessibility at Hox-regulated promoters during zebrafish embryogenesis. Developmental Cell. 17(4):561-567
Nakamura, M., Choe, S.K., Runko, A.P., Gardner, P.D., and Sagerström, C.G. (2008) Nlz1/Znf703 acts as a repressor of transcription. BMC Developmental Biology. 8:108
Choe, S.K., Hirsch, N., Zhang, X., and Sagerström, C.G. (2008) hnf1b genes in zebrafish hindbrain development. Zebrafish. 5(3):179-187
diIorio, P., Alexa, K., Choe, S.K., Etheridge, L., and Sagerström, C.G. (2007) TALE-Family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm. Developmental Biology. 304(1):221-231
Choe, S.K., and Sagerström, C.G. (2005) Variable Meis-dependence among paralog group-1 Hox proteins. Biochemical and Biophysical Research Communications. 331(4):1384-1391
Sagerström, C.G., Gammill, L.S., Veale, R., and Sive, H. (2005) Specification of the enveloping layer and lack of autoneuralization in zebrafish embryonic explants. Developmental dynamics : an official publication of the American Association of Anatomists. 232(1):85-97
Nakamura, M., Runko, A.P., Sagerström, C.G. (2004) A novel subfamily of zinc finger genes involved in embryonic development. Journal of cellular biochemistry. 93:887-95
Choe, S.K., and Sagerström, C.G. (2004) Paralog group 1 hox genes regulate rhombomere 5/6 expression of vhnf1, a repressor of rostral hindbrain fates, in a meis-dependent manner. Developmental Biology. 271(2):350-361
Runko, A.P. and Sagerström, C.G. (2004) Isolation of nlz2 and characterization of essential domains in Nlz-family proteins. The Journal of biological chemistry. 279(12):11917-11925
Roy, N.M., and Sagerström, C.G. (2004) An early Fgf signal required for gene expression in the zebrafish hindbrain primordium. Dev. Brain Res.. 148(1):27-42
Runko, A.P. and Sagerström, C.G. (2003) Nlz belongs to a family of zinc-finger-containing repressors and controls segmental gene expression in the zebrafish hindbrain. Developmental Biology. 262(2):254-267
Lane, M.E., Runko, A.P., Roy, N.M., and Sagerström, C.G. (2002) RETRACTED: Dynamic expression and regulation by Fgf8 and Pou2 of the zebrafish LIM-only gene, lmo4. Gene expression patterns : GEP. 2(3-4):207-211
Lane, M.E., Runko, A.P., Roy, N.M., and Sagerström, C.G. (2002) Dynamic expression and regulation by Fgf8 and Pou2 of the zebrafish LIM-only gene, lmo4. Mechanisms of Development. (Suppl.) 119:S185-S189
Etheridge, L., diIorio, P. and Sagerström, C.G. (2002) A zebrafish unc-45 related gene expressed during muscle development. Developmental dynamics : an official publication of the American Association of Anatomists. 224(4):457-460
Choe, S.K., Vlachakis, N., and Sagerström (2002) Meis proteins are essential for hindbrain development in the zebrafish. Developmental Biology. 247(2):495
Runko, A.P., and Sagerström, C.G. (2002) Roles of the nlz zinc finger protein in zebrafish development. Developmental Biology. 247(2):494-495
Choe, S.K., Vlachakis, N., and Sagerström, C.G. (2002) Meis family proteins are required for hindbrain development in the zebrafish. Development (Cambridge, England). 129(3):585-595
Sagerström, C.G., Kao, B.A., Lane, M.E., and Sive, H. (2001) Isolation and characterization of posteriorly restricted genes in the zebrafish gastrula. Developmental dynamics : an official publication of the American Association of Anatomists. 220(4):402-408
Vlachakis, N., Choe, S.K., and Sagerström, C.G. (2001) Meis3 synergizes with Pbx4 and Hoxb1b in promoting hindbrain fates in the zebrafish. Development (Cambridge, England). 128(8):1299-1312
Vlachakis, N., Ellstrom, D.R., and Sagerström, C.G. (2000) A novel Pbx family member expressed during early zebrafish embryogenesis forms trimeric complexes with Meis3 and Hoxb1b. Developmental dynamics : an official publication of the American Association of Anatomists. 217(1):109-119
Grinblat, Y., Lane, M.E., Sagerström, C., and Sive, H. (1999) Analysis of zebrafish development using explant culture assays. In The Zebrafish: Biology. H.W. Detrich, L.I. Zon, and M. Westerfield, eds. Methods Cell Biol.. 59:127-156
Sagerström, C.G., Grinblat, Y., and Sive, H. (1996) Anteroposterior patterning in the zebrafish, Danio rerio: an explant assay reveals inductive and suppressive cell interactions. Development (Cambridge, England). 122:1873-1883