header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-LAB-001018-2
Amacher Lab
PI/Director: Amacher, Sharon
Contact Person: Amacher, Sharon
Email: amacher.6@osu.edu
URL: http://molgen.osu.edu/amacher
Address: The Ohio State University 125 Rightmire Hall 1060 Carmack Road Columbus, OH 43210
Country: United States
Phone: (614) 688-1338
Fax:
Line Designation: oz


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 15 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Berberoglu, Michael Post-Doc Gallagher, Thomas Post-Doc Maxwell, Adrienne Post-Doc
Talbot, Jared Post-Doc Tietz, Kiel Graduate Student Wachholder, Kimberly Graduate Student
Leist, Rachel Fish Facility Staff Derr, Nicolas Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS x
Hao, L.T., Duy, P.Q., An, M., Talbot, J., Iyer, C.C., Wolman, M., Beattie, C.E. (2017) HuD and the Survival Motor Neuron protein interact in motoneurons and are essential for motoneuron development, function and mRNA regulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(48):11559-11571
Stainier, D.Y.R., Raz, E., Lawson, N.D., Ekker, S.C., Burdine, R.D., Eisen, J.S., Ingham, P.W., Schulte-Merker, S., Yelon, D., Weinstein, B.M., Mullins, M.C., Wilson, S.W., Ramakrishnan, L., Amacher, S.L., Neuhauss, S.C.F., Meng, A., Mochizuki, N., Panula, P., Moens, C.B. (2017) Guidelines for morpholino use in zebrafish. PLoS Genetics. 13:e1007000
Morrow, Z.T., Maxwell, A.M., Hoshijima, K., Talbot, J.C., Grunwald, D.J., Amacher, S.L. (2017) tbx6l and tbx16 are redundantly required for posterior paraxial mesoderm formation during zebrafish embryogenesis. Developmental dynamics : an official publication of the American Association of Anatomists. 246(10):759-769
Gallagher, T.L., Tietz, K.T., Morrow, Z.T., McCammon, J.M., Goldrich, M.L., Derr, N.L., Amacher, S.L. (2017) Pnrc2 regulates 3'UTR-mediated decay of segmentation clock-associated transcripts during zebrafish segmentation. Developmental Biology. 429(1):225-239
Duy, P.Q., Berberoglu, M.A., Beattie, C.E., Hall, C.W. (2017) Cellular responses to recurrent pentylenetetrazole-induced seizures in the adult zebrafish brain. Neuroscience. 349:118-127
Berberoglu, M.A., Gallagher, T.L., Morrow, Z.T., Talbot, J.C., Hromowyk, K.J., Tenente, I.M., Langenau, D.M., Amacher, S.L. (2017) Satellite-like cells contribute to pax7-dependent skeletal muscle repair in adult zebrafish. Developmental Biology. 424(2):162-180
Li, M., Hromowyk, K.J., Amacher, S.L., Currie, P.D. (2017) Muscular dystrophy modeling in zebrafish. Methods in cell biology. 138:347-380
Miguel, J.C., Maxwell, A.A., Hsieh, J.J., Harnisch, L.C., Al Alam, D., Polk, D.B., Lien, C.L., Watson, A.J., Frey, M.R. (2017) Epidermal growth factor suppresses intestinal epithelial cell shedding via a MAPK dependent pathway. Journal of Cell Science. 130(1):90-96
Nissim, S., Weeksb, O., Talbot, J.C., Hedgepeth, J.W., Wucherpfennig, J., Schatzman-Bone, S., Swinburne, I., Cortes, M., Alexa, K., Megason, S., North, T.E., Amacher, S.L., Goessling, W. (2016) Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development. Developmental Biology. 418(1):108-23
Talbot, J.C., Nichols, J.T., Yan, Y.L., Leonard, I.F., BreMiller, R.A., Amacher, S.L., Postlethwait, J.H., Kimmel, C.B. (2016) Pharyngeal morphogenesis requires fras1-itga8- dependent epithelial-mesenchymal interaction. Developmental Biology. 416(1):136-48
Martin, B.L., Gallagher, T.L., Rastogi, N., Davis, J.P., Beattie, C.E., Amacher, S.L., Janssen, P.M. (2015) In vivo assessment of contractile strength distinguishes differential gene function in skeletal muscle of zebrafish larvae. Journal of applied physiology (Bethesda, Md. : 1985). 119(7):799-806
Shih, N.P., François, P., Delaune, E.A., Amacher, S.L. (2015) Dynamics of the slowing segmentation clock reveal alternating two-segment periodicity. Development (Cambridge, England). 142:1785-93
Talbot, J.C., Amacher, S.L. (2014) A Streamlined CRISPR Pipeline to Reliably Generate Zebrafish Frameshifting Alleles. Zebrafish. 11:583-585
Berberoglu, M.A., Dong, Z., Li, G., Zheng, J., Trejo Martinez, L.d.e.l. .C., Peng, J., Wagle, M., Reichholf, B., Petritsch, C., Li, H., Pleasure, S.J., Guo, S. (2014) Heterogeneously Expressed fezf2 Patterns Gradient Notch Activity in Balancing the Quiescence, Proliferation, and Differentiation of Adult Neural Stem Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:13911-23
Seredick, S., Hutchinson, S.A., Van Ryswyk, L., Talbot, J.C., Eisen, J.S. (2014) Lhx3 and Lhx4 suppress Kolmer-Agduhr interneuron characteristics within zebrafish axial motoneurons. Development (Cambridge, England). 141(20):3900-9
Schötz, E.M., Lanio, M., Talbot, J.A., and Manning, M.L. (2013) Glassy dynamics in three-dimensional embryonic tissues. Journal of the Royal Society, Interface. 10(89):20130726
MacDonald, R.B., Pollack, J.N., Debiais-Thibaud, M., Heude, E., Talbot, J.C., and Ekker, M. (2013) The ascl1a and dlx genes have a regulatory role in the development of GABAergic interneurons in the zebrafish diencephalon. Developmental Biology. 381(1):276-85
Fior, R., Maxwell, A.A., Ma, T.P., Vezzaro, A., Moens, C.B., Amacher, S.L., Lewis, J., and Saúde, L. (2012) The differentiation and movement of presomitic mesoderm progenitor cells are controlled by Mesogenin 1. Development (Cambridge, England). 139(24):4656-4665
Delaune, E.A., François, P., Shih, N.P., and Amacher, S.L. (2012) Single-cell-resolution imaging of the impact of notch signaling and mitosis on segmentation clock dynamics. Developmental Cell. 23(5):995-1005
Talbot, J.C., Walker, M.B., Carney, T.J., Huycke, T.R., Yan, Y.L., Bremiller, R.A., Gai, L., Delaurier, A., Postlethwait, J.H., Hammerschmidt, M., and Kimmel, C.B. (2012) fras1 shapes endodermal pouch 1 and stabilizes zebrafish pharyngeal skeletal development. Development (Cambridge, England). 139(15):2804-2813
Parra, M.K., Gallagher, T.L., Amacher, S.L., Mohandas, N., and Conboy, J.G. (2012) Deep intron elements mediate nested splicing events at consecutive AG-dinucleotides to regulate alternative 3' splice site choice in vertebrate 4.1 genes. Molecular and cellular biology. 32(11):2044-2053
Dehnert, K.W., Baskin, J.M., Laughlin, S.T., Beahm, B.J., Naidu, N.N., Amacher, S.L., and Bertozzi, C.R. (2012) Imaging the Sialome during Zebrafish Development with Copper-Free Click Chemistry. Chembiochem : a European journal of chemical biology. 13(3):353-357
Gallagher, T.L., Arribere, J.A., Geurts, P.A., Exner, C.R., McDonald, K.L., Dill, K.K., Marr, H.L., Adkar, S.S., Garnett, A.T., Amacher, S.L., and Conboy, J.G. (2011) Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions. Developmental Biology. 359(2):251-61
Dehnert, K.W., Beahm, B.J., Huynh, T.T., Baskin, J.M., Laughlin, S.T., Wang, W., Wu, P., Amacher, S.L., and Bertozzi, C.R. (2011) Metabolic Labeling of Fucosylated Glycans in Developing Zebrafish. ACS Chemical Biology. 6(6):547-52
Davis, E.E., Zhang, Q., Liu, Q., Diplas, B.H., Davey, L.M., Hartley, J., Stoetzel, C., Szymanska, K., Ramaswami, G., Logan, C.V., Muzny, D.M., Young, A.C., Wheeler, D.A., Cruz, P., Morgan, M., Lewis, L.R., Cherukuri, P., Maskeri, B., Hansen, N.F., Mullikin, J.C., Blakesley, R.W., Bouffard, G.G., NISC Comparative Sequencing Program, Gyapay, G., Rieger, S., Tönshoff, B., Kern, I., Soliman, N.A., Neuhaus, T.J., Swoboda, K.J., Kayserili, H., Gallagher, T.E., Lewis, R.A., Bergmann, C., Otto, E.A., Saunier, S., Scambler, P.J., Beales, P.L., Gleeson, J.G., Maher, E.R., Attié-Bitach, T., Dollfus, H., Johnson, C.A., Green, E.D., Gibbs, R.A., Hildebrandt, F., Pierce, E.A., Katsanis, N. (2011) TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum. Nature Genetics. 43(3):189-196
McCammon, J.M., Doyon, Y., and Amacher, S.L. (2011) Inducing High Rates of Targeted Mutagenesis in Zebrafish Using Zinc Finger Nucleases (ZFNs). Methods in molecular biology (Clifton, N.J.). 770:505-527
Macdonald, R.B., Debiais-Thibaud, M., Talbot, J.C., and Ekker, M. (2010) The relationship between dlx and gad1 expression indicates highly conserved genetic pathways in the zebrafish forebrain. Developmental dynamics : an official publication of the American Association of Anatomists. 239(8):2298-2306
Talbot, J.C., Johnson, S.L., and Kimmel, C.B. (2010) hand2 and Dlx genes specify dorsal, intermediate and ventral domains within zebrafish pharyngeal arches. Development (Cambridge, England). 137(15):2507-2517
Baskin, J.M., Dehnert, K.W., Laughlin, S.T., Amacher, S.L., and Bertozzi, C.R. (2010) Visualizing enveloping layer glycans during zebrafish early embryogenesis. Proc. Natl. Acad. Sci. USA. 107(23):10360-10365
McCammon, J.M., and Amacher, S.L. (2010) Using zinc finger nucleases for efficient and heritable gene disruption in zebrafish. Methods in molecular biology (Clifton, N.J.). 649:281-298
Garnett, A.T., Han, T.M., Gilchrist, M.J., Smith, J.C., Eisen, M.B., Wardle, F.C., and Amacher, S.L. (2009) Identification of direct T-box target genes in the developing zebrafish mesoderm. Development (Cambridge, England). 136(5):749-760
Amacher, S.L. (2008) Emerging gene knockout technology in zebrafish: zinc-finger nucleases. Briefings in functional genomics & proteomics. 7(6):460-464
Doyon, Y., McCammon, J.M., Miller, J.C., Faraji, F., Ngo, C., Katibah, G.E., Amora, R., Hocking, T.D., Zhang, L., Rebar, E.J., Gregory, P.D., Urnov, F.D., and Amacher, S.L. (2008) Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases. Nat. Biotechnol.. 26(6):702-708
Laughlin, S.T., Baskin, J.M., Amacher, S.L., and Bertozzi, C.R. (2008) In vivo imaging of membrane-associated glycans in developing zebrafish. Science (New York, N.Y.). 320(5876):664-667
Ouyang, M., Garnett, A.T., Han, T.M., Hama, K., Lee, A., Deng, Y., Lee, N., Liu, H.Y., Amacher, S.L., Farber, S.A., and Ho, S.Y. (2008) A web based resource characterizing the zebrafish developmental profile of over 16,000 transcripts. Gene expression patterns : GEP. 8(3):171-180
Daggett, D.F., Domingo, C.R., Currie, P.D., and Amacher, S.L. (2007) Control of morphogenetic cell movements in the early zebrafish myotome. Developmental Biology. 309(2):169-179
Walker, M.B., Miller, C.T., Talbot, J.C., Stock, D.W., and Kimmel, C.B. (2006) Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning. Developmental Biology. 295(1):194-205
Dill, K.K., and Amacher, S.L. (2005) tortuga refines Notch pathway gene expression in the zebrafish presomitic mesoderm at the post-transcriptional level. Developmental Biology. 287(2):225-236
Henry, C.A., McNulty, I.M., Durst, W.A., Munchel, S.E., and Amacher, S.L. (2005) Interactions between muscle fibers and segment boundaries in zebrafish. Developmental Biology. 287(2):346-360
Henry, C.A., and Amacher, S.L. (2004) Zebrafish slow muscle cell migration induces a wave of fast muscle morphogenesis. Developmental Cell. 7(6):917-923
Daggett, D.F., Boyd, C.A,. Gautier, P., Bryson-Richardson, R.J., Thisse, C., Thisse, B., Amacher, S.L., and Currie, P.D. (2004) Developmentally restricted actin-regulatory molecules control morphogenetic cell movements in the zebrafish gastrula. Current biology : CB. 14(18):632-638
Henry, C.A., Urban, M.K., Dill, K.K., Merlie, J.P., Page, M.F., Kimmel, C.B., and Amacher, S.L. (2002) Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to refine alternating somite boundaries. Development (Cambridge, England). 129(15):3693-3704
Amacher, S.L., Draper, B.W., Summers, B.R., and Kimmel, C.B. (2002) The zebrafish T-box genes no tail and spadetail are required for development of trunk and tail mesoderm and medial floor plate. Development (Cambridge, England). 129(14):3311-3323
Brennan, C., Amacher, S.L., and Currie, P.D. (2002) Somitogenesis. Results and problems in cell differentiation. 40:271-297
Gray, M., Moens, C.B., Amacher, S.L., Eisen, J.S., and Beattie, C.E. (2001) Zebrafish deadly seven functions in neurogenesis. Developmental Biology. 237(2):306-323
Amacher, S.L. (1999) Transcriptional regulation during zebrafish embryogenesis. Current opinion in genetics & development. 9(5):548-552
Griffin, K.J.P., Amacher, S.L., Kimmel, C.B., and Kimelman, D. (1998) Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes. Development (Cambridge, England). 125:3379-3388
Yamamoto, A., Amacher, S.L., Kim, S.-H., Geissert, D., Kimmel, C.B., and De Robertis, E.M. (1998) Zebrafish paraxial protocadherin is a downstream target of spadetail involved in morphogenesis of gastrula mesoderm. Development (Cambridge, England). 125:3389-3397
Amacher, S.L. and Kimmel, C.B. (1998) Promoting notochord fate and repressing muscle development in zebrafish axial mesoderm. Development (Cambridge, England). 125:1397-1406
Amacher, S.L. and Kimmel, C.B. (1998) Does vertebrate segmentation utilize pair-rules?. Developmental Biology. 198:201
Halpern, M.E., Hatta, K., Amacher, S.L., Talbot, W.S., Yan, Y.-L., Thisse, B., Thisse, C., Postlethwait, J.H., and Kimmel, C.B. (1997) Genetic interactions in zebrafish midline development. Developmental Biology. 187(2):154-170
Fisher, S., Amacher, S.L., and Halpern, M.E. (1997) Loss of cerebum function ventralizes the zebrafish embryo. Development (Cambridge, England). 124(7):1301-1311
Devoto, S.H., Melancon, E., Amacher, S.L., Eisen, J.S., and Westerfield, M. (1996) Influence of axial mesoderm on the development of slow muscle precursors. Developmental Biology. 175(2):386