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Fig. 4 Effect of motion type on recanalization time. 3 nL of tPA-functionalized µwheels containing ~8.4 pg of tPA were infused into 3 dpf zebrafish larvae following injury causing completely occlusive thrombi. Under switchback (n = 8), flipping (n = 10), or rolling (n = 11) modes of movement all recanalized within 30 min, while µwheels under corkscrew (n = 11) movement recanalized within 15 min (**P < 0.01 by Mantel-Cox log-rank testing). Bars represent median recanalization time.
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