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Fig. 1 Islet area. Tg(insulin::GFP) zebrafish embryos were imaged and measured at 96 hpf following exposure to 50 nM tris(4-chlorophenyl)methanol (TCPMOH), 50 nM tris(4-chlorophenyl)methane (TCPM), or 0.01% DMSO. Asterisks * designate statistically significant changes from controls (p < .05). n = 25–29 embryos per treatment group. (a) Mean islet area of embryos exposed to 50 nM TCPMOH and 50 nM TCPM were reduced by 20.8% and 6.8%, respectively, compared to controls. (b) The incidence of hypermorphic or hypomorphic islets was not statistically significant.
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