ZFIN Image: Sigloch et al., 2023, Fig. 1.

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Figure Caption

Fig. 1.

Notch-dependent and -independent her gene expression. (A-R′) her6, her9, her4 (her4.1-4.5 cluster probe), her15 (her15.1 and her15.2 cluster probe), her8a and her8.2 expression (WISH). 48 hpf WT sibling controls (mib1^+/+ or mib1^+/ta52b) (A-F) and mib1^ta52b mutants (A′-F′). (G-L′) Heat shock overexpression of NICD compared with heat-shocked WT siblings at 72 hpf. (M-R′) Notch inhibition by LY-411575 (64 to 72 hpf) in 72 hpf larvae and DMSO controls. Sagittal optical sections at midline (lateral views, single DIC image planes, anterior at left, dorsal at top). pth, prethalamus; rh, rhombencephalon; tec, tectum opticum; tel, telencephalon; th, thalamus. Scale bar: 100 µm.

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