IMAGE

Figure 1

ID
ZDB-IMAGE-230221-4
Source
Figures for van der Plas et al., 2023
Image
Figure Caption

Figure 1

cRBMs construct Hidden Units by grouping neurons into assemblies.

(A) The neural activity of zebrafish larvae was imaged using light-sheet microscopy (left), which resulted in brain-scale, single-cell resolution data sets (middle, microscopy image of a single plane shown for fish #1). Calcium activity ΔF/F was deconvolved to binarized spike traces for each segmented cell (right, example neuron). (B) cRBM sparsely connects neurons (left) to Hidden Units (HUs, right). The neurons that connect to a given HU (and thus belong to the associated assembly), are depicted by the corresponding color labeling (right panel). Data sets typically consist of N104 neurons and M102 HUs. The activity of 500 randomly chosen example neurons (raster plot, left) and HUs 99, 26, 115 (activity traces, right) of the same time excerpt is shown. HU activity is continuous and is determined by transforming the neural activity of its assembly. (C) The neural assemblies of an example data set (fish #3) are shown by coloring each neuron according to its strongest-connecting HU. 7 assemblies are highlighted (starting rostrally at the green forebrain assembly, going clockwise: HU 177, 187, 7, 156, 124, 64, 178), by showing their neurons with a connection |w|0.1. See Figure 3 for more anatomical details of assemblies. R: Right, L: Left, Ro: Rostral, C: Caudal.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife