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Figure 6.
(A) hBuChE recovery after preincubation of compound 3f diluted to 1× or 0.1 × IC50, compared to donepezil (done.) and rivastigmine (riva.) diluted, and undiluted inhibition. (B) hBuChE recovery of donepezil, rivastigmine and 3f diluted to 0.1 × IC50, were monitored with time at room temperature for 240 min. Data were expressed as the mean ± SD by three independent experiments.
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Full text @ J Enzyme Inhib Med Chem