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Fig. 4 Lanosterol reverses the loss of transparency of isolated porcine lens ex vivo. (A) Schematic of soaking assays. The isolated porcine lenses were treated with Jao-Liu (JL) solution for two days followed by incubation with vehicle β-CD and lanosterol (LS) in β-CD solution for eight days. The clarity of lenses was determined every two days. The detail baseline and treatment data are summarized in Supplementary Table S7. (B.) Gray-scale quantification of porcine lenses. The results are expressed as means ± standard deviation. Detailed gray scales and sample number are summarized in Supplementary Tables S8 and S9. *P < 0.05, independent t-test.